{"id":4520,"date":"2022-01-20T11:54:29","date_gmt":"2022-01-20T19:54:29","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/stevens-ini-receives-private-funding-for-much-needed-bipolar-disorder-research\/"},"modified":"2023-11-19T12:50:49","modified_gmt":"2023-11-19T20:50:49","slug":"stevens-ini-receives-private-funding-for-much-needed-bipolar-disorder-research","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/stevens-ini-receives-private-funding-for-much-needed-bipolar-disorder-research\/","title":{"rendered":"Stevens INI receives private funding for much-needed bipolar disorder research"},"content":{"rendered":"\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--article-hero \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--article-hero\"\n    \n      >\n\n    \n  <div class=\"text-container\">\n              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <span>Press Release<\/span>\n\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--page-title\">\n\n    \n  <h1>Stevens INI receives private funding for much-needed bipolar disorder research<\/h1>\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--description\">\n\n    \n  <p>This serious mental health disorder comes with dramatic and sometimes unpredictable shifts in mood, energy and activity levels.<\/p>\n\n\n\n<\/div>\n    \n          <div class=\"meta\">\n                  <span class=\"author\">Sidney Taiko Sheehan<\/span>\n        \n                  <span class=\"date\">January 20, 2022<\/span>\n              <\/div>\n    \n              \n<div class=\"f--field f--embed\">\n\n    \n  <div class=\"heateor_sss_sharing_container heateor_sss_horizontal_sharing\" data-heateor-ss-offset=\"0\" data-heateor-sss-href='https:\/\/keck.usc.edu\/news\/stevens-ini-receives-private-funding-for-much-needed-bipolar-disorder-research\/'><div class=\"heateor_sss_sharing_ul\"><a aria-label=\"Facebook\" class=\"heateor_sss_facebook\" 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data-src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/ENIGMA-768x432.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/ENIGMA-1920x1080.jpg 1920w,https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/ENIGMA-1280x720.jpg 1280w,https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/ENIGMA-768x432.jpg 768w\"          data-sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from institutions across the globe. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from thousands of subjects. Photo credit: USC Stevens INI.\"\n        \n                                      \/>\n\n    \n          <figcaption>The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from institutions across the globe. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from thousands of subjects. Photo credit: USC Stevens INI.<\/figcaption>\n    <\/figure>\n    \n  \n  \n\n<\/div>\n  \n\n  <\/div><\/div>\n\r\n\r\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Bipolar disorder is a chronically underfunded and understudied mental health condition that affects 2.3 million Americans, and nearly 45 million people worldwide. This serious mental health disorder comes with dramatic and sometimes unpredictable shifts in mood, energy and activity levels. Bipolar disorder is characterized by disruptive recurrences of mania and depression that may last for weeks, months or even years. In addition to the immeasurable personal impact, the economic burden of bipolar disorder is estimated to be approximately $200 billion annually in the U.S. alone.<\/p>\n<figure id=\"attachment_124956\" aria-describedby=\"caption-attachment-124956\" style=\"width: 261px\" class=\"wp-caption alignright\"><a href=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Chris-Ching.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-124956 size-medium\" src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Chris-Ching-261x300.png\" alt=\"Christopher R. K. Ching, PhD\" width=\"261\" height=\"300\" \/><\/a><figcaption id=\"caption-attachment-124956\" class=\"wp-caption-text\">Christopher R. K. Ching, PhD<\/figcaption><\/figure>\n<p>In 2012, The ENIGMA Bipolar Disorder Working Group formed a large collaborative neuroimaging study to advance our understanding of the brain mechanisms underlying bipolar disorder. Christopher R. K. Ching, PhD, a postdoctoral fellow and <a href=\"https:\/\/researchtraining.nih.gov\/programs\/training-grants\/t32\">NIH T32 training grant<\/a> recipient with the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (<a href=\"https:\/\/ini.usc.edu\/\">USC INI<\/a>) at the Keck School of Medicine of USC, serves as co-chair of this effort, an expanding international team of 150 leading researchers from 20 countries and 55 research institutions, including a growing sample of over 12,000 research subjects.<\/p>\n<p>\u201cA critical barrier to improving diagnosis and treatment outcomes for individuals with bipolar disorder is a limited understanding of how commonly prescribed medications influence brain structure and function. A better grasp of how common treatments influence the brain could help us understand why particular treatments are helpful for some and not others,\u201d says Ching. \u201cThe goal of this project is to use our large-scale collaborative research network and advanced analysis techniques to map the complex relationship between bipolar disorder, common medications and other clinical factors. This could identify potential brain signatures that predict treatment response, illness progression and ultimately help improve patient outcomes.\u201d<\/p>\n<p>\u201cAnother key goal of our work will be to actively engage patients, caregivers, clinicians and other stakeholders to disseminate our scientific goals and research findings. By improving our collective understanding of how medications for bipolar disorder work in the brain, we hope to better align our research with the goals of patients, leading to better treatment and care for those with mental illness,\u201d says Ching\u2019s research advisor, <a href=\"https:\/\/keck.usc.edu\/faculty-search\/paul-m-thompson\/\">Paul M. Thompson<\/a>, associate director of the USC INI.<\/p>\n<p>This past spring, the <a href=\"https:\/\/milkeninstitute.org\/\">Milken Institute<\/a> and the Baszucki Brain Research Fund launched a dedicated grant program aimed at advancing therapeutic discovery for bipolar disorder. The Fund selected Thompson and Ching\u2019s promising work and will provide $200,000 over the course of one year. Another USC INI postdoctoral researcher and NIH T32 training grant recipient, Leila Nabulsi, PhD, is also heavily involved in the work.<\/p>\n<p>\u201cIt\u2019s important to note that an NIH T32 training grant allowed me the unique opportunity to continue the foundational work I conducted during my graduate training, and today I continue to lead large-scale, international neuroimaging efforts. The T32 was instrumental in preparing me for where I am now. It\u2019s so encouraging to get training grant support that then puts you in the position to find more dedicated funding like the Baszucki Brain Research Fund, so you have even more resources to innovate in your work.\u201d<\/p>\n<p>INI Director <a href=\"https:\/\/keck.usc.edu\/faculty-search\/arthur-w-toga\/\">Arthur Toga<\/a>, principal investigator of the T32 that supported Ching, is pleased to see how the pipeline of experiential learning and training is leading to successful funding for early career investigators. \u201cOne of my top priorities is to ensure that all members of the INI, be they graduate students or postdocs or faculty members, have the support and resources to grow and develop their work. I\u2019m excited to see what the team can accomplish with this new award.\u201d<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":156,"featured_media":4521,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[56,169,20],"class_list":["post-4520","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-featured","tag-latest","tag-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Stevens INI receives private funding for much-needed bipolar disorder research<\/title>\n<meta name=\"robots\" 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