{"id":482,"date":"2015-10-08T15:56:00","date_gmt":"2015-10-08T22:56:00","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/hear-and-now-restoring-sound-perception-after-hearing-loss\/"},"modified":"2023-11-26T08:16:48","modified_gmt":"2023-11-26T16:16:48","slug":"hear-and-now-restoring-sound-perception-after-hearing-loss","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/hear-and-now-restoring-sound-perception-after-hearing-loss\/","title":{"rendered":"Hear, and Now: Restoring Sound Perception After Hearing Loss"},"content":{"rendered":"\n \n \n\n\n\n\n\n\n\n
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\n\n \n Press Release<\/span>\n\n\n\n<\/div>\n \n \n
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Hear, and Now: Restoring Sound Perception After Hearing Loss<\/h1>\n\n\n<\/div>\n \n \n
\n \n October 08, 2015<\/span>\n <\/div>\n \n \n
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A cochlear implant means Shane Lundie can now hear his mother\u2019s voice. Photo by Steve Cohn<\/figcaption>\n <\/figure>\n \n \n \n\n<\/div>\n \n\n <\/div><\/div>\n\r\n\r\n\n\n \n \n\n\n\n\n\n\n\n
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The Caruso family was caught up in a movie at home earlier this year when daughter Gianna, 15, made the announcement that would change her father\u2019s life.
\n\u201cDad and Mom, I hear the rain.\u201d
\nRick Caruso \u201980 smiled. \u201cYeah, it\u2019s raining,\u201d he said, turning his attention back to the movie.
\n\u201cNo, Dad,\u201d said the teen. \u201cI hear the rain.\u201d
\nHer words clicked. Born with inner-ear hearing loss, Gianna had just done what was once impossible for her. Rick and Tina Caruso realized that their daughter could hear even the faint tapping of raindrops, thanks to a recently implanted hearing device.
\nSuch life-changing leaps happen daily within the USC Tina and Rick Caruso Department of Otolaryngology \u2013 Head and Neck Surgery, renowned for its innovative treatments and research addressing hearing loss in children and adults.
\nKeck Medicine of USC physicians\u2019 efforts to break the sound barrier are gaining added momentum from a transformative $25 million gift from the Caruso family. Their gift in June endowed and named not only the USC Caruso Department, but also the USC Caruso Family Center for Childhood Communication, a treatment center affiliated with Children\u2019s Hospital Los Angeles.
\n\u201cThis is a very personal mission for us,\u201d says Caruso, a USC Trustee who graduated with honors from the USC Marshall School of Business.
\nFor physician John K. Niparko, the support bolsters what he calls a \u201ctalented, dedicated team\u201d in the department.
\n\u201cThe fact that we have partners like the Caruso family is beyond expectation and quite humbling\u2014it inspires us all the more,\u201d says Niparko, chair of the USC Caruso Department and the Leon J. Tiber and David S. Alpert Chair in Medicine at the Keck School of Medicine of USC.
\nTwo years ago, working in tandem with audiologist Kristina Rousso, Niparko introduced Gianna to a new, in-the-ear device, which sits deep in both of her ear canals. When it was activated, Gianna began to cry. It was the first time she\u2019d heard her parents\u2019 voices clearly. \u201cIt was a great day\u2014one of the most amazing days in our lives,\u201d Gianna\u2019s father says.
\nThat experience motivated the Carusos to ask an important question, he says: \u201cWhat more could we do to help kids who don\u2019t have the ability to get this kind of medical support or technology?\u201d
\nThe need is there. About one in 1,000 children has profound hearing loss at birth, and by 5 years, that increases to one in 500. The impact can be dramatic. \u201cEarly sound exposure is absolutely essential for a child\u2019s development in so many dimensions,\u201d Niparko says. \u201cWe have an opportunity to engage the brain circuits of the developing child in the first few years\u2014circuits highly dedicated to language learning.\u201d
\nNiparko is a leading authority on implantable technologies and principal investigator on a 14-year National Institutes of Health (NIH)-funded study on cochlear implants. He\u2019s also passionate about music and art\u2014both of which are, \u201cat their core, about communication,\u201d he says.
\nAndy and Jennifer Garcia of Long Beach, California, wanted to help their daughter Amanda access that world after she was born with mild to moderate hearing loss caused by a virus. At first, Amanda did well with a single hearing aid. Then, a serious ear infection left her deaf in one ear. As Amanda\u2019s hearing deteriorated, so did her speech and her self-confidence, recalls her mother. The family turned to Niparko for help, and at age 9, Amanda received a cochlear implant. The moment it switched on, \u201cher eyes got big!\u201d Jennifer Garcia says.
\nThe cochlear implant differs from a hearing aid\u2014essentially an amplifier\u2014by bypassing the damaged cochlea, part of the inner ear with nerve endings essential for hearing, to directly stimulate the auditory nerve. With training, children learn to recognize the sounds of language. For many, that work takes place at the USC Caruso Family Center, where audiologists, speech-language pathologists and education experts from Keck School of Medicine and Children\u2019s Hospital Los Angeles care for some 5,000 children and young people annually. Expect that number to expand, especially as interactions between the USC Caruso Family Center and its partner on the same campus\u2014John Tracy Clinic\u2014continue to grow.
\nThe Lundie family went through the journey with their son Shane, who was born profoundly deaf. When he was about a year old, Shane underwent a successful cochlear implant procedure, allowing him to hear sound for the first time. But the journey didn\u2019t end there. The Lundies worked closely with the USC Caruso Family Center for Childhood Communication to ensure that he continued developing his hearing and communication skills.
\nAt the USC Caruso Family Center, families like the Lundies and Garcias first enter a sound booth equipped with state-of-the-art audiometers that focus on frequencies in the speech range. Young children use puzzle pieces to signal when a sound registers. Even babies can be evaluated: When they turn their heads at a sound, they\u2019re rewarded with the sight of a toy bear playing the drums. Speech-language pathologists also use play-based activities to assess a child\u2019s language skills. Just five months after hearing sound for the first time, Shane was able to say a new word: \u201cMama.\u201d It was, as his mother Kelly puts it, the \u201cbest Christmas gift ever.\u201d
\n\u201cWe want each child to have the richest possible language experience,\u201d says pediatric audiologist Margaret Winter. To that end, the USC Caruso Family Center has also developed its own literacy-training program\u2014\u201cCome Read With Me\u201d\u2014for families who speak English as their second language. Children, teachers and parents participate. Analysis shows major gains in children\u2019s reading and writing years after training. Following this summer\u2019s program, one mother noted that her daughter \u201cnow prefers books over Barbies,\u201d Niparko says.
\nOther research explores new technologies. For children missing an auditory nerve\u2014necessary to transmit sound from inner ear to brain\u2014the answer may lie in what\u2019s called an auditory brainstem implant, or ABI. The FDA approved a Phase I clinical trial for ABI in children under 5 years old through the Keck School of Medicine, working with the House Clinic.
\nIn the five-year clinical trial\u2014the only one in the U.S. to gain NIH funding\u2014House Clinic and Children\u2019s Hospital Los Angeles surgeons will implant ABI devices in as many as 10 children, who will be monitored for three years. With the first procedure in 2014, it\u2019s too soon to tell how well the ABI may help children develop speech over time. \u201cThat\u2019s a question we all hope to answer,\u201d says Keck Medicine audiologist Laurie Eisenberg, study co-leader.
\nOver the course of her career, Eisenberg has seen the field of assistive devices flourish. \u201cForty years ago, no one could have predicted where we are today,\u201d she says.
\nOthers in the department turn to human biology to target hearing loss. In his quest to understand the embryonic development of the inner ear, USC researcher Takahiro Ohyama recently identified a key molecular sequence that may someday open up avenues for gene therapy.
\nAnd scientist Neil Segil studies cellular reprogramming to try to regenerate hair cells, delicate structures in the inner ear that are critical for hearing.
\nSome animal species, including birds, frogs and fish, can regenerate damaged or lost hearing by growing new hair cells. Mammals can\u2019t. But Segil\u2019s team was the first to show that what are called supporting cells\u2014neighbors to hair cells\u2014could be reprogrammed in mammals to generate hair cells at an early stage of life. Now Segil, a professor of research, is tapping into stem cell techniques developed at the Keck School of Medicine that trigger skin cells to turn into other types of cells. Preliminary data suggest that hair cells develop directly from a type of skin-related stem cell, Segil says. It\u2019s early, but he\u2019s cautiously excited about the possibilities.
\nToday Gianna, Amanda, Shane and others like them are beneficiaries of decades of advances in hearing research. Gianna can now hear her coaches when she competes in her equestrian events, and she wants to volunteer at the USC Caruso Family Center. Amanda, 10, felt confident enough to talk to her Girl Scout troop about her cochlear implant. Two-year-old Shane loves to dance to the radio. And he\u2019s catching words \u201ceven at a whisper\u2014mind-boggling!\u201d says his mother. Every time Shane hears a new sound, he points to his ear and says another word Mom loves to hear.
\n\u201cOn.\u201d
\nBy Candace Pearson<\/p>\n\n\n\n<\/div>\n <\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":168,"featured_media":483,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[56,16],"class_list":["post-482","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-featured","tag-otolaryngology"],"acf":[],"yoast_head":"\nHear, and Now: Restoring Sound Perception After Hearing Loss<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/keck.usc.edu\/news\/hear-and-now-restoring-sound-perception-after-hearing-loss\/\" \/>\n<meta property=\"og:locale\" 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