{"id":508,"date":"2015-10-23T08:56:08","date_gmt":"2015-10-23T15:56:08","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/grant-to-fund-tissue-regeneration-center\/"},"modified":"2023-11-19T12:07:55","modified_gmt":"2023-11-19T20:07:55","slug":"grant-to-fund-tissue-regeneration-center","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/grant-to-fund-tissue-regeneration-center\/","title":{"rendered":"Grant to fund tissue regeneration center"},"content":{"rendered":"\n \n \n\n\n\n\n\n\n\n
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\n\n \n Press Release<\/span>\n\n\n\n<\/div>\n \n \n
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Grant to fund tissue regeneration center<\/h1>\n\n\n<\/div>\n \n \n
\n John Hobbs<\/span>\n \n October 23, 2015<\/span>\n <\/div>\n \n \n
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Yang Chai, DDS, PhD<\/figcaption>\n <\/figure>\n \n \n \n\n<\/div>\n \n\n <\/div><\/div>\n\r\n\r\n\n\n \n \n\n\n\n\n\n\n\n
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Tissue regeneration is getting a boost from a $2 million grant divided among 10 research centers and universities, including the Herman Ostrow School of Dentistry of USC.
\nThe National Institute for Dental and Craniofacial Research has directed the research community to devise interdisciplinary groups to help bring to market safe and effective clinical strategies for dental, oral and craniofacial tissue regeneration.
\n\u201cThis is really about engineering a product,\u201d said Yang Chai, DDS, PhD, associate dean of research at the Herman Ostrow School of Dentistry of USC. \u201cIt\u2019s not only about being able to understand what stem cells can do, but also how you deliver the stem cells for patient care.\u201d
\nChai will serve as the principal investigator of USC\u2019s interdisciplinary consortium \u2014 called the Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration (C-DOCTOR) \u2014 which has enlisted nearly 30 individuals from USC Viterbi School of Engineering, Keck School of Medicine of USC<\/a>, Children\u2019s Hospital Los Angeles and USC School of Pharmacy.
\nThe first task will be to identify areas in which tissue regeneration could improve patient outcomes and have immediate impact. For this endeavor, Chai has enlisted representatives from endodontics, oral surgery, periodontics and prosthodontics to make product suggestions based on their own clinical practices.
\nAn example is developing an effective strategy to use a 3-D printed, dissolvable scaffold to help organize stem cells for repair of damaged jaw bone.
\n\u201cBone deficiency is a very common problem that patients face when they need an implant or when they have periodontal disease, traumatic injury or birth defect,\u201d Chai said. \u201cInstead of stealing bone from other parts of the body, we\u2019re going to be able to use stem cells to regenerate their own bone.\u201d
\nIn addition to the clinical team, the interdisciplinary group will feature a pre-clinical team whose role is to develop experimental protocols and sound statistical methods to test potential therapies as well as a regulatory team that will interface with the Food and Drug Administration and provide guidance regarding intellectual property protection.
\nThe grant money will be awarded in phases, with Phase One awards lasting a year and supporting the development of an overall vision, road map, organizational structure and operational procedure.
\nEach of the 10 grantees will then have to compete for a Phase Two award, which will provide additional funding for three to four years.<\/p>\n\n\n\n<\/div>\n <\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":118,"featured_media":509,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[17],"class_list":["post-508","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-stem-cell"],"acf":[],"yoast_head":"\nGrant to fund tissue regeneration center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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