{"id":5691,"date":"2024-02-05T12:08:35","date_gmt":"2024-02-05T20:08:35","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/?p=5691"},"modified":"2024-02-05T12:31:39","modified_gmt":"2024-02-05T20:31:39","slug":"usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/","title":{"rendered":"USC researchers uncover biological circuit that protects plants from extreme conditions"},"content":{"rendered":"\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--article-hero \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--article-hero\"\n    \n      >\n\n    \n  <div class=\"text-container\">\n              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <span>Press Release<\/span>\n\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--page-title\">\n\n    \n  <h1>USC researchers uncover biological circuit that protects plants from extreme conditions<\/h1>\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--description\">\n\n    \n  <p>A new study shows that plants use their circadian clocks to regulate responses to changes in water and salinity, offering a new avenue for creating drought-resistant crops.<\/p>\n\n\n\n<\/div>\n    \n          <div class=\"meta\">\n                  <span class=\"author\">Zara Abrams<\/span>\n        \n                  <span class=\"date\">February 05, 2024<\/span>\n              <\/div>\n    \n              \n<div class=\"f--field f--embed\">\n\n    \n  <div class=\"heateor_sss_sharing_container heateor_sss_horizontal_sharing\" data-heateor-ss-offset=\"0\" data-heateor-sss-href='https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/'><div class=\"heateor_sss_sharing_ul\"><a aria-label=\"Facebook\" class=\"heateor_sss_facebook\" href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fusc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions%2F\" title=\"Facebook\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg\" style=\"background-color:#0765FE;width:32px;height:32px;display:inline-block;opacity:1;float:left;font-size:32px;box-shadow:none;display:inline-block;font-size:16px;padding:0 4px;vertical-align:middle;background-repeat:repeat;overflow:hidden;padding:0;cursor:pointer;box-sizing:content-box\"><svg style=\"display:block;\" focusable=\"false\" aria-hidden=\"true\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 32 32\"><path fill=\"#fff\" d=\"M28 16c0-6.627-5.373-12-12-12S4 9.373 4 16c0 5.628 3.875 10.35 9.101 11.647v-7.98h-2.474V16H13.1v-1.58c0-4.085 1.849-5.978 5.859-5.978.76 0 2.072.15 2.608.298v3.325c-.283-.03-.775-.045-1.386-.045-1.967 0-2.728.745-2.728 2.683V16h3.92l-.673 3.667h-3.247v8.245C23.395 27.195 28 22.135 28 16Z\"><\/path><\/svg><\/span><\/a><a aria-label=\"X\" class=\"heateor_sss_button_x\" href=\"https:\/\/twitter.com\/intent\/tweet?text=USC%20researchers%20uncover%20biological%20circuit%20that%20protects%20plants%20from%20extreme%20conditions&#038;url=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fusc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions%2F\" title=\"X\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg heateor_sss_s__default heateor_sss_s_x\" style=\"background-color:#2a2a2a;width:32px;height:32px;display:inline-block;opacity:1;float:left;font-size:32px;box-shadow:none;display:inline-block;font-size:16px;padding:0 4px;vertical-align:middle;background-repeat:repeat;overflow:hidden;padding:0;cursor:pointer;box-sizing:content-box\"><svg width=\"100%\" height=\"100%\" style=\"display:block;\" focusable=\"false\" aria-hidden=\"true\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 32 32\"><path fill=\"#fff\" d=\"M21.751 7h3.067l-6.7 7.658L26 25.078h-6.172l-4.833-6.32-5.531 6.32h-3.07l7.167-8.19L6 7h6.328l4.37 5.777L21.75 7Zm-1.076 16.242h1.7L11.404 8.74H9.58l11.094 14.503Z\"><\/path><\/svg><\/span><\/a><a aria-label=\"Linkedin\" class=\"heateor_sss_button_linkedin\" href=\"https:\/\/www.linkedin.com\/sharing\/share-offsite\/?url=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fusc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions%2F\" title=\"Linkedin\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg heateor_sss_s__default heateor_sss_s_linkedin\" style=\"background-color:#0077b5;width:32px;height:32px;display:inline-block;opacity:1;float:left;font-size:32px;box-shadow:none;display:inline-block;font-size:16px;padding:0 4px;vertical-align:middle;background-repeat:repeat;overflow:hidden;padding:0;cursor:pointer;box-sizing:content-box\"><svg style=\"display:block;\" focusable=\"false\" aria-hidden=\"true\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 32 32\"><path d=\"M6.227 12.61h4.19v13.48h-4.19V12.61zm2.095-6.7a2.43 2.43 0 0 1 0 4.86c-1.344 0-2.428-1.09-2.428-2.43s1.084-2.43 2.428-2.43m4.72 6.7h4.02v1.84h.058c.56-1.058 1.927-2.176 3.965-2.176 4.238 0 5.02 2.792 5.02 6.42v7.395h-4.183v-6.56c0-1.564-.03-3.574-2.178-3.574-2.18 0-2.514 1.7-2.514 3.46v6.668h-4.187V12.61z\" fill=\"#fff\"><\/path><\/svg><\/span><\/a><a aria-label=\"Whatsapp\" class=\"heateor_sss_whatsapp\" href=\"https:\/\/api.whatsapp.com\/send?text=USC%20researchers%20uncover%20biological%20circuit%20that%20protects%20plants%20from%20extreme%20conditions%20https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fusc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions%2F\" title=\"Whatsapp\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg\" style=\"background-color:#55eb4c;width:32px;height:32px;display:inline-block;opacity:1;float:left;font-size:32px;box-shadow:none;display:inline-block;font-size:16px;padding:0 4px;vertical-align:middle;background-repeat:repeat;overflow:hidden;padding:0;cursor:pointer;box-sizing:content-box\"><svg style=\"display:block;\" focusable=\"false\" aria-hidden=\"true\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"100%\" height=\"100%\" viewBox=\"-6 -5 40 40\"><path class=\"heateor_sss_svg_stroke heateor_sss_no_fill\" stroke=\"#fff\" stroke-width=\"2\" fill=\"none\" d=\"M 11.579798566743314 24.396926207859085 A 10 10 0 1 0 6.808479557110079 20.73576436351046\"><\/path><path d=\"M 7 19 l -1 6 l 6 -1\" class=\"heateor_sss_no_fill heateor_sss_svg_stroke\" stroke=\"#fff\" stroke-width=\"2\" fill=\"none\"><\/path><path d=\"M 10 10 q -1 8 8 11 c 5 -1 0 -6 -1 -3 q -4 -3 -5 -5 c 4 -2 -1 -5 -1 -4\" fill=\"#fff\"><\/path><\/svg><\/span><\/a><a aria-label=\"Telegram\" class=\"heateor_sss_button_telegram\" href=\"https:\/\/telegram.me\/share\/url?url=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fusc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions%2F&#038;text=USC%20researchers%20uncover%20biological%20circuit%20that%20protects%20plants%20from%20extreme%20conditions\" title=\"Telegram\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg heateor_sss_s__default heateor_sss_s_telegram\" style=\"background-color:#3da5f1;width:32px;height:32px;display:inline-block;opacity:1;float:left;font-size:32px;box-shadow:none;display:inline-block;font-size:16px;padding:0 4px;vertical-align:middle;background-repeat:repeat;overflow:hidden;padding:0;cursor:pointer;box-sizing:content-box\"><svg style=\"display:block;\" focusable=\"false\" aria-hidden=\"true\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 32 32\"><path fill=\"#fff\" d=\"M25.515 6.896L6.027 14.41c-1.33.534-1.322 1.276-.243 1.606l5 1.56 1.72 5.66c.226.625.115.873.77.873.506 0 .73-.235 1.012-.51l2.43-2.363 5.056 3.734c.93.514 1.602.25 1.834-.863l3.32-15.638c.338-1.363-.52-1.98-1.41-1.577z\"><\/path><\/svg><\/span><\/a><a aria-label=\"PrintFriendly\" class=\"heateor_sss_button_printfriendly\" href=\"https:\/\/www.printfriendly.com\/print?url=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fusc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions%2F&#038;partner=a2a\" title=\"PrintFriendly\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg heateor_sss_s__default heateor_sss_s_printfriendly\" style=\"background-color:#61d1d5;width:32px;height:32px;display:inline-block;opacity:1;float:left;font-size:32px;box-shadow:none;display:inline-block;font-size:16px;padding:0 4px;vertical-align:middle;background-repeat:repeat;overflow:hidden;padding:0;cursor:pointer;box-sizing:content-box\"><svg style=\"display:block;\" focusable=\"false\" aria-hidden=\"true\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 32 32\"><g stroke=\"#fff\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-miterlimit=\"10\"><path fill=\"none\" d=\"M22.562 19.588v4.373H9.438v-4.37h13.124zm-13.124 1.53H6.375c-.483 0-.875-.313-.875-.7v-7.35c0-.387.392-.7.875-.7h19.25c.482 0 .875.313.875.7v7.35c0 .387-.393.7-.876.7h-3.062\"><\/path><path fill=\"#fff\" d=\"M22.562 12.32V8.04H9.436v4.28\"><\/path><\/g><\/svg><\/span><\/a><a aria-label=\"Copy Link\" class=\"heateor_sss_button_copy_link\" title=\"Copy Link\" rel=\"noopener\" href=\"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/\" onclick=\"event.preventDefault()\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg heateor_sss_s__default heateor_sss_s_copy_link\" style=\"background-color:#ffc112;width:32px;height:32px;display:inline-block;opacity:1;float:left;font-size:32px;box-shadow:none;display:inline-block;font-size:16px;padding:0 4px;vertical-align:middle;background-repeat:repeat;overflow:hidden;padding:0;cursor:pointer;box-sizing:content-box\"><svg style=\"display:block;\" focusable=\"false\" aria-hidden=\"true\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"100%\" height=\"100%\" viewBox=\"-4 -4 40 40\"><path fill=\"#fff\" d=\"M24.412 21.177c0-.36-.126-.665-.377-.917l-2.804-2.804a1.235 1.235 0 0 0-.913-.378c-.377 0-.7.144-.97.43.026.028.11.11.255.25.144.14.24.236.29.29s.117.14.2.256c.087.117.146.232.177.344.03.112.046.236.046.37 0 .36-.126.666-.377.918a1.25 1.25 0 0 1-.918.377 1.4 1.4 0 0 1-.373-.047 1.062 1.062 0 0 1-.345-.175 2.268 2.268 0 0 1-.256-.2 6.815 6.815 0 0 1-.29-.29c-.14-.142-.223-.23-.25-.254-.297.28-.445.607-.445.984 0 .36.126.664.377.916l2.778 2.79c.243.243.548.364.917.364.36 0 .665-.118.917-.35l1.982-1.97c.252-.25.378-.55.378-.9zm-9.477-9.504c0-.36-.126-.665-.377-.917l-2.777-2.79a1.235 1.235 0 0 0-.913-.378c-.35 0-.656.12-.917.364L7.967 9.92c-.254.252-.38.553-.38.903 0 .36.126.665.38.917l2.802 2.804c.242.243.547.364.916.364.377 0 .7-.14.97-.418-.026-.027-.11-.11-.255-.25s-.24-.235-.29-.29a2.675 2.675 0 0 1-.2-.255 1.052 1.052 0 0 1-.176-.344 1.396 1.396 0 0 1-.047-.37c0-.36.126-.662.377-.914.252-.252.557-.377.917-.377.136 0 .26.015.37.046.114.03.23.09.346.175.117.085.202.153.256.2.054.05.15.148.29.29.14.146.222.23.25.258.294-.278.442-.606.442-.983zM27 21.177c0 1.078-.382 1.99-1.146 2.736l-1.982 1.968c-.745.75-1.658 1.12-2.736 1.12-1.087 0-2.004-.38-2.75-1.143l-2.777-2.79c-.75-.747-1.12-1.66-1.12-2.737 0-1.106.392-2.046 1.183-2.818l-1.186-1.185c-.774.79-1.708 1.186-2.805 1.186-1.078 0-1.995-.376-2.75-1.13l-2.803-2.81C5.377 12.82 5 11.903 5 10.826c0-1.08.382-1.993 1.146-2.738L8.128 6.12C8.873 5.372 9.785 5 10.864 5c1.087 0 2.004.382 2.75 1.146l2.777 2.79c.75.747 1.12 1.66 1.12 2.737 0 1.105-.392 2.045-1.183 2.817l1.186 1.186c.774-.79 1.708-1.186 2.805-1.186 1.078 0 1.995.377 2.75 1.132l2.804 2.804c.754.755 1.13 1.672 1.13 2.75z\"\/><\/svg><\/span><\/a><\/div><div class=\"heateorSssClear\"><\/div><\/div>\n\n\n<\/div>\n        \n  <\/div>\n\n          \n<div class=\"f--field f--image\">\n\n    \n    \n    \n        <figure>\n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy-768x432.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy-768x432.jpg 768w\"          data-sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Bioluminescent image of Arabidopsis seedlings expressing circadian clock reporter genes in response to water stress. Tong Liang, PhD\/ Kay laboratory, USC\"\n        \n                                      \/>\n\n    \n          <figcaption><p>Bioluminescent image of Arabidopsis seedlings expressing circadian clock reporter genes in response to water stress. Tong Liang, PhD\/ Kay laboratory, USC<\/p>\n<\/figcaption>\n    <\/figure>\n    \n  \n  \n\n<\/div>\n  \n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Climate change is already harming agricultural yields and may one day <a href=\"https:\/\/www.epa.gov\/climateimpacts\/climate-change-impacts-agriculture-and-food-supply\">pose a significant threat<\/a> to the world\u2019s food supply. Engineering more resilient crops, including those able to thrive in the face of drought or high soil salinity levels, is an increasingly urgent need.<\/p>\n<p>A new study from the <a href=\"https:\/\/keck.usc.edu\/\">Keck School of Medicine of USC<\/a>, funded by the National Institutes of Health, reveals details about how plants regulate their responses to stress that may prove crucial to those efforts. Researchers found that plants use their circadian clocks to respond to changes in external water and salt levels throughout the day. That same circuitry\u2014an elegant feedback loop controlled by a protein known as ABF3\u2014also helps plants adapt to extreme conditions such as drought. The results were just published in the journal Proceedings of the National Academy of Sciences.<\/p>\n<p>\u201cThe bottom line is plants are stuck in place. They can\u2019t run around and grab a drink of water. They can\u2019t move into the shade when they want to or away from soil that has excess salt. Because of that, they\u2019ve evolved to use their circadian clocks to exquisitely measure and adapt to their environment,\u201d said the study\u2019s senior author, <a href=\"https:\/\/keck.usc.edu\/faculty-search\/steve-kay\/\">Steve A. Kay, PhD<\/a>, University and Provost Professor of Neurology, Biomedical Engineering and Quantitative Computational Biology at the Keck School of Medicine and Director of the <a href=\"https:\/\/michelson.usc.edu\/\">USC Michelson Center for Convergent Bioscience<\/a>.<\/p>\n<p><iframe loading=\"lazy\" title=\"The Interplay between the Circadian Clock and Abiotic Stress Responses Mediated by ABF3 and CCA1\/LHY\" width=\"500\" height=\"375\" src=\"https:\/\/www.youtube.com\/embed\/Ezjx7FgxXCg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p><em>A timelapse image of the plants glowing on and off with a 24h circadian rhythm. Researchers use luciferase to measure clock-regulated gene expression directly in the live plants. Tong Liang, PhD\/ Kay laboratory, USC<\/em><\/p>\n<p>The findings build on a long line of research from <a href=\"https:\/\/kaylab.usc.edu\/\">Kay\u2019s lab<\/a> on the role of circadian clock proteins in both plants and <a href=\"https:\/\/keck.usc.edu\/news\/study-shows-how-liver-cancer-hijacks-circadian-clock-machinery-inside-cells\/\">animals<\/a>. Clock proteins, which regulate biological changes over the course of the day, may provide a shrewd solution to an ongoing challenge in crop engineering. Creating drought-resistant plants is difficult, because plants respond to stress by slowing their own growth and development\u2014an overblown stress response means an underperforming plant.<\/p>\n<p>\u201cThere\u2019s a delicate balance between boosting a plant\u2019s stress tolerance while maximizing its growth and yield,\u201d Kay said. \u201cSolving this challenge is made all the more urgent by climate change.\u201d<\/p>\n<p><strong>Finding the feedback loop<\/strong><\/p>\n<p>Previous plant biology research showed that clock proteins regulate about 90% of genes in plants and are central to their responses to temperature, light intensity and day length, including seasonal changes that determine when they flower. But one big outstanding question was whether and how clock proteins control the way plants handle changing water and soil salinity levels.<\/p>\n<p>To explore the link, Kay and his team studied Arabidopsis, a plant commonly used in research because it is small, has a rapid life cycle, a relatively simple genome and shares common traits and genes with many agricultural crops. They created a library of all of the more than 2000 Arabidopsis transcription factors, which are proteins that control the way genes are expressed under different circumstances. Transcription factors can provide key insights about regulation of biological processes. The researchers then built a data analysis pipeline to analyze each transcription factor and search for associations.<\/p>\n<p>\u201cWe got a really big surprise: that many of the genes the clock was regulating were associated with drought responses,\u201d Kay said, particularly those controlling the hormone abscisic acid, a type of stress hormone that plants produce when water levels are very high or very low.<\/p>\n<p>The analysis revealed that abscisic acid levels are controlled by clock proteins as well as the transcription factor ABF3 in what Kay calls a \u201chomeostatic feedback loop.\u201d Over the course of a day, clock proteins regulate ABF3 to help plants respond to changing water levels, then ABF3 feeds information back to clock proteins to keep the stress response in check. That same loop helps plants adapt when conditions become extreme, for instance during a drought. Genetic data also revealed a similar process for handling changes in soil salinity levels.<\/p>\n<p>\u201cWhat\u2019s really special about this circuit is that it allows the plant to respond to external stress while keeping its stress response under control, so that it can continue to grow and develop,\u201d Kay said.<\/p>\n<p><strong>Engineering better crops<\/strong><\/p>\n<p>The findings point to two new approaches that may help boost crop resilience. For one, agricultural breeders can search and select for naturally occurring genetic diversity in the circadian ABF3 circuit that gives plants a slight edge in responding to water and salinity stress. Even a small increase in resilience could substantially improve crop yield on a large scale.<\/p>\n<p>Kay and his colleagues also plan to explore a genetic modification approach, using CRISPR to engineer genes that promote ABF3 in order to design highly drought-resistant plants.<\/p>\n<p>\u201cThis could be a significant breakthrough in thinking about how to modulate crop plants to be more drought resistant,\u201d Kay said.<\/p>\n<p><strong>About this research<\/strong><\/p>\n<p>In addition to Kay, the study&#8217;s other authors are Tong Liang, Shi Yu, Yuanzhong Pan and Jiarui Wang from the Department of Neurology, Keck School of Medicine, University of Southern California.<\/p>\n<p>This work is supported by National Institute of General Medical Sciences of the National Institutes of Health [R37 GM067837].<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":128,"featured_media":5696,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[234,20],"class_list":["post-5691","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-department-of-neurology","tag-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>USC researchers uncover biological circuit that protects plants from extreme conditions<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"USC researchers uncover biological circuit that protects plants from extreme conditions\" \/>\n<meta property=\"og:url\" content=\"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/\" \/>\n<meta property=\"og:site_name\" content=\"Newsroom\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/KECKschoolUSC\/\" \/>\n<meta property=\"article:published_time\" content=\"2024-02-05T20:08:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-02-05T20:31:39+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"912\" \/>\n\t<meta property=\"og:image:height\" content=\"513\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Laura LeBlanc\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@KeckSchool_USC\" \/>\n<meta name=\"twitter:site\" content=\"@KeckSchool_USC\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/\"},\"author\":{\"name\":\"Laura LeBlanc\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#\\\/schema\\\/person\\\/cedc1eb148768537246d92d51056275e\"},\"headline\":\"USC researchers uncover biological circuit that protects plants from extreme conditions\",\"datePublished\":\"2024-02-05T20:08:35+00:00\",\"dateModified\":\"2024-02-05T20:31:39+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/\"},\"wordCount\":11,\"publisher\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/wp-content\\\/uploads\\\/sites\\\/68\\\/2024\\\/02\\\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg\",\"keywords\":[\"Department of Neurology\",\"Research\"],\"articleSection\":[\"Press Release\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/\",\"name\":\"USC researchers uncover biological circuit that protects plants from extreme conditions\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/wp-content\\\/uploads\\\/sites\\\/68\\\/2024\\\/02\\\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg\",\"datePublished\":\"2024-02-05T20:08:35+00:00\",\"dateModified\":\"2024-02-05T20:31:39+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/#primaryimage\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/wp-content\\\/uploads\\\/sites\\\/68\\\/2024\\\/02\\\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg\",\"contentUrl\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/wp-content\\\/uploads\\\/sites\\\/68\\\/2024\\\/02\\\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg\",\"width\":912,\"height\":513,\"caption\":\"Bioluminescent image of Arabidopsis seedlings expressing circadian clock reporter genes in response to water stress. Tong Liang, PhD\\\/ Kay laboratory, USC\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"USC researchers uncover biological circuit that protects plants from extreme conditions\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#website\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/\",\"name\":\"Newsroom\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#organization\",\"name\":\"Keck School of Medicine of USC\",\"alternateName\":\"Keck School of Medicine\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/wp-content\\\/uploads\\\/sites\\\/68\\\/2023\\\/11\\\/keck-school-of-medicine-logo-696-square.jpg\",\"contentUrl\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/wp-content\\\/uploads\\\/sites\\\/68\\\/2023\\\/11\\\/keck-school-of-medicine-logo-696-square.jpg\",\"width\":696,\"height\":696,\"caption\":\"Keck School of Medicine of USC\"},\"image\":{\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/KECKschoolUSC\\\/\",\"https:\\\/\\\/x.com\\\/KeckSchool_USC\",\"https:\\\/\\\/www.linkedin.com\\\/school\\\/keckschoolusc\\\/\",\"https:\\\/\\\/www.instagram.com\\\/KeckSchoolUSC\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCpL1E1W5ZTfkc5iihwLSFEA\",\"https:\\\/\\\/www.tiktok.com\\\/@keckschoolusc\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/#\\\/schema\\\/person\\\/cedc1eb148768537246d92d51056275e\",\"name\":\"Laura LeBlanc\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b356795bf86b2e398b4f627159f4e89a3ba3cc9e1899eeedcbc9b7b410a2f041?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b356795bf86b2e398b4f627159f4e89a3ba3cc9e1899eeedcbc9b7b410a2f041?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b356795bf86b2e398b4f627159f4e89a3ba3cc9e1899eeedcbc9b7b410a2f041?s=96&d=mm&r=g\",\"caption\":\"Laura LeBlanc\"},\"url\":\"https:\\\/\\\/keck.usc.edu\\\/news\\\/author\\\/laura_leblanc\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"USC researchers uncover biological circuit that protects plants from extreme conditions","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/","og_locale":"en_US","og_type":"article","og_title":"USC researchers uncover biological circuit that protects plants from extreme conditions","og_url":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/","og_site_name":"Newsroom","article_publisher":"https:\/\/www.facebook.com\/KECKschoolUSC\/","article_published_time":"2024-02-05T20:08:35+00:00","article_modified_time":"2024-02-05T20:31:39+00:00","og_image":[{"width":912,"height":513,"url":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg","type":"image\/jpeg"}],"author":"Laura LeBlanc","twitter_card":"summary_large_image","twitter_creator":"@KeckSchool_USC","twitter_site":"@KeckSchool_USC","twitter_misc":{"Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/#article","isPartOf":{"@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/"},"author":{"name":"Laura LeBlanc","@id":"https:\/\/keck.usc.edu\/news\/#\/schema\/person\/cedc1eb148768537246d92d51056275e"},"headline":"USC researchers uncover biological circuit that protects plants from extreme conditions","datePublished":"2024-02-05T20:08:35+00:00","dateModified":"2024-02-05T20:31:39+00:00","mainEntityOfPage":{"@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/"},"wordCount":11,"publisher":{"@id":"https:\/\/keck.usc.edu\/news\/#organization"},"image":{"@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/#primaryimage"},"thumbnailUrl":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg","keywords":["Department of Neurology","Research"],"articleSection":["Press Release"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/","url":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/","name":"USC researchers uncover biological circuit that protects plants from extreme conditions","isPartOf":{"@id":"https:\/\/keck.usc.edu\/news\/#website"},"primaryImageOfPage":{"@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/#primaryimage"},"image":{"@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/#primaryimage"},"thumbnailUrl":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg","datePublished":"2024-02-05T20:08:35+00:00","dateModified":"2024-02-05T20:31:39+00:00","breadcrumb":{"@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/#primaryimage","url":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg","contentUrl":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy.jpg","width":912,"height":513,"caption":"Bioluminescent image of Arabidopsis seedlings expressing circadian clock reporter genes in response to water stress. Tong Liang, PhD\/ Kay laboratory, USC"},{"@type":"BreadcrumbList","@id":"https:\/\/keck.usc.edu\/news\/usc-researchers-uncover-biological-circuit-that-protects-plants-from-extreme-conditions\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/keck.usc.edu\/news\/"},{"@type":"ListItem","position":2,"name":"USC researchers uncover biological circuit that protects plants from extreme conditions"}]},{"@type":"WebSite","@id":"https:\/\/keck.usc.edu\/news\/#website","url":"https:\/\/keck.usc.edu\/news\/","name":"Newsroom","description":"","publisher":{"@id":"https:\/\/keck.usc.edu\/news\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/keck.usc.edu\/news\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/keck.usc.edu\/news\/#organization","name":"Keck School of Medicine of USC","alternateName":"Keck School of Medicine","url":"https:\/\/keck.usc.edu\/news\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/keck.usc.edu\/news\/#\/schema\/logo\/image\/","url":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/keck-school-of-medicine-logo-696-square.jpg","contentUrl":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/keck-school-of-medicine-logo-696-square.jpg","width":696,"height":696,"caption":"Keck School of Medicine of USC"},"image":{"@id":"https:\/\/keck.usc.edu\/news\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/KECKschoolUSC\/","https:\/\/x.com\/KeckSchool_USC","https:\/\/www.linkedin.com\/school\/keckschoolusc\/","https:\/\/www.instagram.com\/KeckSchoolUSC\/","https:\/\/www.youtube.com\/channel\/UCpL1E1W5ZTfkc5iihwLSFEA","https:\/\/www.tiktok.com\/@keckschoolusc"]},{"@type":"Person","@id":"https:\/\/keck.usc.edu\/news\/#\/schema\/person\/cedc1eb148768537246d92d51056275e","name":"Laura LeBlanc","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/b356795bf86b2e398b4f627159f4e89a3ba3cc9e1899eeedcbc9b7b410a2f041?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/b356795bf86b2e398b4f627159f4e89a3ba3cc9e1899eeedcbc9b7b410a2f041?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/b356795bf86b2e398b4f627159f4e89a3ba3cc9e1899eeedcbc9b7b410a2f041?s=96&d=mm&r=g","caption":"Laura LeBlanc"},"url":"https:\/\/keck.usc.edu\/news\/author\/laura_leblanc\/"}]}},"author_meta":{"display_name":"Laura LeBlanc","author_link":"https:\/\/keck.usc.edu\/news\/author\/laura_leblanc\/"},"featured_img":"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/Kay-Arabidopsis-Seelings-luminescence-copy-300x169.jpg","coauthors":[],"tax_additional":{"categories":{"linked":["<a href=\"https:\/\/keck.usc.edu\/news\/category\/press-release\/\" class=\"advgb-post-tax-term\">Press Release<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Press Release<\/span>"]},"tags":{"linked":["<a href=\"https:\/\/keck.usc.edu\/news\/category\/press-release\/\" class=\"advgb-post-tax-term\">Department of Neurology<\/a>","<a href=\"https:\/\/keck.usc.edu\/news\/category\/press-release\/\" class=\"advgb-post-tax-term\">Research<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">Department of Neurology<\/span>","<span class=\"advgb-post-tax-term\">Research<\/span>"]}},"comment_count":"0","relative_dates":{"created":"Posted 2 years ago","modified":"Updated 2 years ago"},"absolute_dates":{"created":"Posted on February 5, 2024","modified":"Updated on February 5, 2024"},"absolute_dates_time":{"created":"Posted on February 5, 2024 12:08 pm","modified":"Updated on February 5, 2024 12:31 pm"},"featured_img_caption":"Bioluminescent image of Arabidopsis seedlings expressing circadian clock reporter genes in response to water stress. Tong Liang, PhD\/ Kay laboratory, USC","series_order":"","_links":{"self":[{"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/posts\/5691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/users\/128"}],"replies":[{"embeddable":true,"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/comments?post=5691"}],"version-history":[{"count":0,"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/posts\/5691\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/media\/5696"}],"wp:attachment":[{"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/media?parent=5691"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/categories?post=5691"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/keck.usc.edu\/news\/wp-json\/wp\/v2\/tags?post=5691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}