{"id":5974,"date":"2020-08-07T03:37:12","date_gmt":"2020-08-07T10:37:12","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/two-new-studies-explore-how-pollution-affects-the-brain\/"},"modified":"2024-02-12T11:00:41","modified_gmt":"2024-02-12T19:00:41","slug":"two-new-studies-explore-how-pollution-affects-the-brain","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/two-new-studies-explore-how-pollution-affects-the-brain\/","title":{"rendered":"Two new studies explore how pollution affects the brain"},"content":{"rendered":"\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--article-hero \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--article-hero\"\n    \n      >\n\n    \n  <div class=\"text-container\">\n              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <span>Campus News<\/span>\n\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--page-title\">\n\n    \n      <h1>Two new studies explore how pollution affects the brain<\/h1>\n\n\n<\/div>\n    \n    \n          <div class=\"meta\">\n        \n                  <span class=\"date\">August 07, 2020<\/span>\n              <\/div>\n    \n              \n<div class=\"f--field f--embed\">\n\n    \n  <div class=\"heateor_sss_sharing_container heateor_sss_horizontal_sharing\" data-heateor-ss-offset=\"0\" data-heateor-sss-href='https:\/\/keck.usc.edu\/news\/two-new-studies-explore-how-pollution-affects-the-brain\/'><div class=\"heateor_sss_sharing_ul\"><a aria-label=\"Facebook\" class=\"heateor_sss_facebook\" href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Ftwo-new-studies-explore-how-pollution-affects-the-brain%2F\" title=\"Facebook\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg\" 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11.903 5 10.826c0-1.08.382-1.993 1.146-2.738L8.128 6.12C8.873 5.372 9.785 5 10.864 5c1.087 0 2.004.382 2.75 1.146l2.777 2.79c.75.747 1.12 1.66 1.12 2.737 0 1.105-.392 2.045-1.183 2.817l1.186 1.186c.774-.79 1.708-1.186 2.805-1.186 1.078 0 1.995.377 2.75 1.132l2.804 2.804c.754.755 1.13 1.672 1.13 2.75z\"\/><\/svg><\/span><\/a><\/div><div class=\"heateorSssClear\"><\/div><\/div>\n\n\n<\/div>\n        \n  <\/div>\n\n          \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/air-pollution-children-web-768x432.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/air-pollution-children-web-1280x720.jpg 1280w,https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2024\/02\/air-pollution-children-web-768x432.jpg 768w\"          data-sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"          class=\"lazyload\"\n        \n                alt=\"smog graphic\"\n\n        \n                \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n  \n\n  <\/div><\/div>\n\r\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>USC researchers are investigating the impact of fine particle pollution on child brain growth and in older women who aren\u2019t eating enough fish.<\/p>\n<figure class=\"wp-block-image size-large\"><figcaption>Fine particle pollution can alter a child\u2019s brain. (Illustration\/iStock)<\/figcaption><\/figure>\n<p>A pair of recently published USC studies add to our growing understanding of how fine particle pollution \u2014 the tiny, inhalable pollutants from cars and power plants \u2014 impacts our brains.<\/p>\n<p>The first study, published in&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0160412020318882\" target=\"_blank\" rel=\"noreferrer noopener\">Environment International<\/a>, found that these fine particles \u2014 known as PM2.5 \u2014 may alter the size of a child\u2019s developing brain, which may ultimately increase the risk for cognitive and emotional problems later in adolescence.<\/p>\n<p>\u201cAt this young age, the neurons in children\u2019s brains are expanding and pruning at an incredible rate. As your brain develops, it wants to create efficient pathways,\u201d said lead author&nbsp;<a href=\"https:\/\/keck.usc.edu\/faculty-search\/megan-m-herting\/\" target=\"_blank\" rel=\"noreferrer noopener\">Megan Herting<\/a>, an assistant professor at the Keck School of Medicine of USC. \u201cIf these pathways are altered by PM2.5 exposure, and different parts of the brain are maturing and making connections at different rates, that might set you up for individual differences later on.\u201d<\/p>\n<p>USC, located in what the&nbsp;<a href=\"http:\/\/www.stateoftheair.org\/city-rankings\/most-polluted-cities.html\" target=\"_blank\" rel=\"noreferrer noopener\">American Lung Association<\/a>&nbsp;frequently cites as the most polluted city in the nation, is home to a robust air pollution research program. Findings from its studies have led to changes in state and federal guidelines to improve air quality standards. One of its cornerstones is the USC&nbsp;<a href=\"https:\/\/healthstudy.usc.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">Children\u2019s Health Study<\/a>, one of the largest and most detailed studies of the long-term effects of air pollution.<\/p>\n<p>Herting\u2019s team used MRI scans from nearly 11,000 children aged 9 and 10 from 21 cities across the United States and matched each scan with yearly pollution data for each child\u2019s residence. This is the first study of its kind to show that, even at relatively low levels, current PM2.5 exposure may be an important environmental factor that influences patterns of brain development in American children.<\/p>\n<p>When they compared highly exposed kids with those who had less exposure to PM2.5, they saw differences. For example, areas associated with emotion were larger in highly exposed kids, while other areas associated with cognitive functioning were smaller.<\/p>\n<p>Herting plans to follow the progress of the children, who are part of the&nbsp;<a href=\"https:\/\/abcdstudy.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">ABCD Study<\/a>, the largest long-term study of brain health and child development in the United States.<\/p>\n<h2>Eating fish could help protect women\u2019s brains against fine particle pollution<\/h2>\n<p>The second study, published in&nbsp;<a href=\"https:\/\/n.neurology.org\/content\/early\/2020\/07\/15\/WNL.0000000000010074.abstract\" target=\"_blank\" rel=\"noreferrer noopener\">Neurology<\/a>, found that omega-3 fatty acids from consuming fish may protect against PM 2.5-associated brain shrinkage in older women.<\/p>\n<p><a href=\"https:\/\/news.usc.edu\/163089\/air-pollution-brain-changes-alzheimers-memory-usc-study\/\">Previous USC research<\/a>&nbsp;showed that women in their 70s and 80s who were exposed to higher levels of air pollution experienced greater declines in memory and more Alzheimer\u2019s-like brain atrophy than their counterparts who breathed cleaner air.<\/p>\n<p>For this study, researchers looked at the brain MRIs of 1,315 women aged 65 to 80 and blood test results to determine levels of healthy omega-3 fatty acids in their blood.<\/p>\n<p>\u201cWe found that women with higher blood levels of omega-3s had larger volumes of white matter in their brains. Women living in locations with higher PM2.5 tended to have smaller white matter in their brains, but such damage that may be caused by PM2.5 was greatly reduced in women with high blood levels of omega-3 fatty acids,\u201d said corresponding author&nbsp;<a href=\"https:\/\/keck.usc.edu\/faculty-search\/jiu-chiuan-chen\/\" target=\"_blank\" rel=\"noreferrer noopener\">Jiu-Chiuan Chen<\/a>, an associate professor at the Keck School of Medicine of USC.<\/p>\n<p>The brain\u2019s white matter, in contrast to gray matter, makes up most of the volume of the brain. It is the vast, intertwining system of neural connections that unites different regions of the brain that perform various mental operations. White matter loss may be an early marker of Alzheimer\u2019s disease.<\/p>\n<p>&#8211; By\u00a0<a href=\"https:\/\/news.usc.edu\/author\/leigh-hopper\/\">Leigh Hopper<\/a><\/p>\n<hr class=\"wp-block-separator\"\/>\n<p><em><strong>About the Environment International study<\/strong>: In addition to Herting, other authors of the study include Dora Cserbik, Jiu-Chiuan Chen, Rob McConnell, Elizabeth R. Sowell, Daniel A. Hackman, all of USC; Kiros Berhane of Mailman School of Public Health of Columbia University; Eric Kan of Children\u2019s Hospital Los Angeles; Joel Schwartz of Harvard T.H. Chan School of Public Health; and Chun C. Fan of UC San Diego.<\/em><\/p>\n<p><em>The study was supported with grants from the National Institute of Environmental Health Sciences (P30ES007048-23S1, 3P30ES000002-55S1, P01ES022845), the Environmental Protection Agency (RD 83587201, RD 83544101) and the Rose Hills Foundation.&nbsp;The larger ABCD study is also supported by the National Institutes of Health (U01DA041048, U01DA050989, U01DA051016, U01DA041022, U01DA051018, U01DA051037, U01DA050987, U01DA041174, U01DA041106, U01DA041117, U01DA041028, U01DA041134, U01DA050988, U01DA051039, U01DA041156, U01DA041025, U01DA041120, U01DA051038, U01DA041148, U01DA041093, U01DA041089, U24DA041123 and U24DA041147).<\/em><\/p>\n<p><em><strong>About the Neurology study<\/strong>: In addition to Chen, other authors of the study include Xinhui Wang and Helena Chui of Keck; Cheng Chen and Ka He of Columbia University; Pengcheng Xun of Indiana University; Joel Kaufman of the University of Washington; Kathleen Hayden and Mark Espeland of Wake Forest School of Medicine; Eric Whitsel, Marc Serre and William Vizuete of University of North Carolina Chapel Hill; Tonya Orchard of Ohio State University; and William Harris of the University of South Dakota.<\/em><\/p>\n<p><em>The study was supported with grants from the National Institutes of Health (R01AG033078, RF1AG054068 and RF1AG056111) and the National Institute of Environmental Health Sciences (R01ES025888).<\/em><\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  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