{"id":61,"date":"2023-08-02T22:52:55","date_gmt":"2023-08-02T22:52:55","guid":{"rendered":"https:\/\/keck.usc.edu\/ophthalmology\/?page_id=61"},"modified":"2026-07-14T21:13:28","modified_gmt":"2026-07-14T21:13:28","slug":"sponsored-research","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/ophthalmology\/research\/sponsored-research\/","title":{"rendered":"Sponsored Research"},"content":{"rendered":"\n\n\n\n\n  \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"\/ophthalmology\/\"  aria-label=\"\/ophthalmology\/\">Department of Ophthalmology<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n      <h1>Sponsored Research<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/keckmedicine.org\/eye\"\n  target=\"_blank\"  >\n        Are you a patient?\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                                  In This Section\n                                <svg class=\"menu\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\"\n                  y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#000\" d=\"M4,23h3v3H4V23z M4,16h3v3H4V16z M10,23\n                  h21v3H10V23z M10,16h21v3H10V16z M10,9h21v3H10V9z M4,9h3v3H4V9z\"\/>\n                <\/svg>\n\n                <svg class=\"close\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\"\n                  viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <polygon fill=\"#000\" fill-rule=\"evenodd\" clip-rule=\"evenodd\" points=\"26,10.4 24.6,9 17.5,16.1 10.4,9 9,10.4 16.1,17.5\n                  9,24.6 10.4,26 17.5,18.9 24.6,26 26,24.6 18.9,17.5 \"\/>\n                <\/svg>\n              <\/button>\n\n              <nav\n  class=\"mc--menu mc--\"\n  >\n  <ul class=\"m--menu m--\">\n    \n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-home menu-item-24 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a 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href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/clinical-trials\/\" >Clinical Trials<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-74\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/publications\/\" >Publications<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-76\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/funding-opportunities\/\" >Funding Opportunities<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-73\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/laboratories\/\" >Laboratories<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-20 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class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-168\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/cornea-external-disease-fellowship\/\" >Cornea, External Diseases &amp; Refractive Surgery<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-169\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/glaucoma-fellowship\/\" >Glaucoma Fellowship<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-170\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/neuro-ophthalmology\/\" >Neuro-Ophthalmology<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-172\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/pediatric-ophthalmology-and-strabismus\/\" >Pediatric Ophthalmology and Strabismus<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-173\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/vitreoretinal-surgery\/\" >Vitreoretinal Surgery<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-174\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/current-fellows\/\" >Current Fellows<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-19\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/patient-care\/\" >Patient Care<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-96 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/faculty\/\" >Faculty<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Faculty\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-695\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/affiliated-faculty\/\" >Affiliated Faculty<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-87\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/support\/\" >Support<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-89\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/contact\/\" >Contact<\/a>\n  \n  \n<\/li>\n\n    \n      <\/ul><!-- m--menu -->\n<\/nav>\n\n            <\/div>\n                  <\/div>\n        <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Our sponsored research portfolio reflects the breadth of vision science at the USC Roski Eye Institute. Active grants are funded by the National Institutes of Health, the National Science Foundation, the California Institute for Regenerative Medicine, and private foundations including Research to Prevent Blindness, the Glaucoma Research Foundation, and the BrightFocus Foundation.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <h2>View by Research Specialty:<\/h2>\n<p><a href=\"#Center\">Center Core for Vision Research<\/a><br \/>\n<a href=\"#ClinSci\">Clinician-Scientist Training Grant<\/a><br \/>\n<a href=\"#Cornea\">Cornea\/Ocular Surface<\/a><br \/>\n<a href=\"#Epid\">Epidemiology<\/a><br \/>\n<a href=\"#Glaucoma\">Glaucoma<\/a><br \/>\n<a href=\"#Neuro\">Neuro-Ophthalmology<\/a><br \/>\n<a href=\"#Ocular\">Ocular Oncology<\/a><br \/>\n<a href=\"#Ped\">Pediatric<\/a><br \/>\n<a href=\"#Retina\">Retina<\/a><br \/>\n<a href=\"#Uveitis\">Uveitis<\/a><br \/>\n<a href=\"#Visual\">Visual Processing<\/a><br \/>\n<a href=\"#Other\">Other<\/a><\/p>\n<h3 id=\"ClinSci\">Center Core for Vision Research<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Center Core for Vision Research<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Mahnaz Shahidi, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 id=\"Cornea\">Clinician-Scientist Training Grant<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">USC Roski Eye K12 Clinician-Vision Scientist Training Program (USC Roski Eye K12)<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Mark Humayun, MD, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Cornea\/Ocular Surface<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Role of Cathepsin S in Dry Eye Associated Neuropathic Pain<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Maria Edman, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Protein-polymer Nanomedicine for Sjogren&#8217;s Syndrome<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Sarah Hamm-Alvarez, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Microtubule-Based Transport in Lacrimal Gland Function<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Sarah Hamm-Alvarez, PhD<\/td>\n<\/tr>\n<tr>\n<td id=\"Epid\" style=\"width: 33.3333%;\">Enhanced Preservation of Donor Corneas<\/td>\n<td style=\"width: 33.3333%;\">OneLegacy Foundation<\/td>\n<td style=\"width: 33.3333%;\">J. Martin Heur, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Reversibly Adhesive Hydrogel for Temporary Treatment of Traumatic Open Globe Injury in Austere Environments<\/td>\n<td style=\"width: 33.3333%;\">DoD<\/td>\n<td style=\"width: 33.3333%;\">John Whalen, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Epidemiology<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td id=\"Glaucoma\" style=\"width: 33.3333%;\">Intrauterine exposure to tobacco smoke, DNA methylation, and vision disorders in preschool children<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Xuejuan Jiang, PhD<\/td>\n<\/tr>\n<tr>\n<td id=\"LowVision\" style=\"width: 33.3333%;\">Integrative Analysis of Genetic and Epigenetic Variation in Maternal Smoking&#8217;s Effect on Child&#8217;s Eye<\/td>\n<td style=\"width: 33.3333%;\">Tobacco-Related Disease Research Program<\/td>\n<td style=\"width: 33.3333%;\">Xuejuan Jiang, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Glaucoma<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Chemically Reprogrammed Retinal Ganglion Cell Therapy to Treat Glaucomatous Neuropathy<\/td>\n<td style=\"width: 33.3333%;\">Glaucoma Research Foundation<\/td>\n<td style=\"width: 33.3333%;\">Biraj Mahato, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure Disease<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Benjamin Xu, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td id=\"Neuro\" style=\"width: 33.3333%;\">Treatment Patterns and Clinical Outcomes in Newly-Diagnosed Cases of Angle Closure With and Without Glaucoma: A Cross-sectional and Longitudinal Analysis<\/td>\n<td style=\"width: 33.3333%;\">American Glaucoma Society<\/td>\n<td style=\"width: 33.3333%;\">Benjamin Xu, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">High-resolution Elastographic Assessment of the Optic Nerve Head<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Qifa Zhou, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Neuro-Ophthalmology<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">In vivo Application of Electrical Fields Directs Retinal Ganglion Cell Axon Regeneration<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Kimberly Gokoffski, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Wearable Early Intervention Electric Stimulation for Optic Nerve Regeneration<\/td>\n<td style=\"width: 33.3333%;\">DoD<\/td>\n<td style=\"width: 33.3333%;\">Kimberly Gokoffski, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">GCR: Reprogramming Biological Neural Networks with Field-Based Engineered Systems<\/td>\n<td style=\"width: 33.3333%;\">NSF<\/td>\n<td style=\"width: 33.3333%;\">Gianluca Lazzi, PhD, MBA; Kimberly Gokoffski, MD, PhD; Mark Humayun, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Electric Fields Collaborate with Cdc42 to Direct Optic Nerve Regeneration<\/td>\n<td style=\"width: 33.3333%;\">BrightFocus Foundation<\/td>\n<td style=\"width: 33.3333%;\">Kimberly Gokoffski, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Directing Axon Growth with Biphasic Electrical Stimulation<\/td>\n<td style=\"width: 33.3333%;\">Baxter Foundation<\/td>\n<td style=\"width: 33.3333%;\">Kimberly Gokoffski, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Biomechanical mapping of the optic nerve head and peripapillary sclera using high frequency ultrasonic elastography<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Qifa Zhou, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Ocular Oncology<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Development of a Surrogate Liquid Biopsy from the Aqueous Humor in Retinoblastoma Eyes<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NCI<\/td>\n<td style=\"width: 33.3333%;\">Jesse Berry, MD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Harnessing the Power of Data to Save Lives: Building the Retinoblastoma Data Commons<\/td>\n<td style=\"width: 33.3333%;\">Children\u2019s Cancer Research Fund<\/td>\n<td style=\"width: 33.3333%;\">Jesse Berry, MD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Molecular characterization of retinoblastoma in vivo using the aqueous humor liquid biopsy<\/td>\n<td style=\"width: 33.3333%;\">Children\u2019s Oncology Group<\/td>\n<td style=\"width: 33.3333%;\">Jesse Berry, MD<\/td>\n<\/tr>\n<tr>\n<td id=\"Ped\" style=\"width: 33.3333%;\">Sensitive detection of minimal residual intraocular disease by analysis of cell-free DNA tumor fraction in the aqueous humor of eyes with retinoblastoma: a step towards precision medicine<\/td>\n<td style=\"width: 33.3333%;\">Wright Foundation<\/td>\n<td style=\"width: 33.3333%;\">Jesse Berry, MD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Successive responses to oncogenic aberrations in retinoblastoma genesis<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NCI<\/td>\n<td style=\"width: 33.3333%;\">David Cobrinik, MD, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Pediatric<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\">Project<\/td>\n<td style=\"width: 33.3333%;\">Sponsor<\/td>\n<td style=\"width: 33.3333%;\">Principal Investigator<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Validating a machine learning model of eye tracking in children with cortical visual impairment (CVI)<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NCI<\/td>\n<td style=\"width: 33.3333%;\">Melinda Chang, MD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Eye tracking and Teller acuity for visual assessment in children with cortical visual impairment (CVI)<\/td>\n<td style=\"width: 33.3333%;\">Blind Children\u2019s Center<\/td>\n<td style=\"width: 33.3333%;\">Jesse Berry, MD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Retina<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\"><strong>Project<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Sponsor<\/strong><\/td>\n<td style=\"width: 33.3333%;\"><strong>Principal Investigator<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Predictive Medicine Inherited Retinal Dystrophy Gene Correction Program<\/td>\n<td style=\"width: 33.3333%;\">Knights Templar Eye Foundation<\/td>\n<td style=\"width: 33.3333%;\">David Cobrinik, MD, PhD; Aaron Nagiel, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">EFRI CEE: Engineered Retinal Epigenomics<\/td>\n<td style=\"width: 33.3333%;\">NSF<\/td>\n<td style=\"width: 33.3333%;\">Mark Humayun, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">PRPE-SF, polarized hESC-derived RPE Soluble Factors, as a Therapy for Early Stage Dry Age-related Macular Degeneration<\/td>\n<td style=\"width: 33.3333%;\">CIRM<\/td>\n<td style=\"width: 33.3333%;\">Mark Humayun, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Chemically reprogrammed M\u00fcller cell derived retinal ganglion cells to study and treat optic nerve hypoplasia<\/td>\n<td style=\"width: 33.3333%;\">Knights Templar Eye Foundation<\/td>\n<td style=\"width: 33.3333%;\">Biraj Mahato, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Role of non-canonical Wnt signaling in the developing human photoreceptor-bipolar cell synapse<\/td>\n<td style=\"width: 33.3333%;\">Research to Prevent Blindness<\/td>\n<td style=\"width: 33.3333%;\">Aaron Nagiel, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Imaging of Retinal Oxygenation and Metabolism<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Mahnaz Shahidi, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Imaging of Retinal Oxygen Metabolism in Diabetic Retinopathy<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Mahnaz Shahidi, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Two-photon Imaging of Oxygen and Blood Flow in Retinal and Cerebral Vasculature<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NINDS<\/td>\n<td style=\"width: 33.3333%;\">Mahnaz Shahidi, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Restoring Sight to the Blind: Neural Imaging with Retinal Prostheses<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Noelle Stiles, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">VRC: A Stem Cell-Based Treatment Strategy for Laser-Induced Permanent Retinal Damages<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Biju Thomas, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Integration and Functionality of Retinal Organoid Transplants<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Biju Thomas, PhD<\/td>\n<\/tr>\n<tr>\n<td id=\"Uveitis\" style=\"width: 33.3333%;\">Single particle analysis of extracellular vesicles in the Aqueous Humor of Retinoblastoma Eyes: Moving towards an Integrated Liquid Biopsy<\/td>\n<td style=\"width: 33.3333%;\">Knights Templar Eye Foundation<\/td>\n<td style=\"width: 33.3333%;\">Liya Xu, PhD<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Non-invasive Ultrasound Stimulated Retinal Prosthesis<\/td>\n<td style=\"width: 33.3333%;\">NIH\/NEI<\/td>\n<td style=\"width: 33.3333%;\">Qifa Zhou, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Uveitis<\/h3>\n<section tabindex=\"0\">\n<div class=\"table-2\">\n<table width=\"100%\">\n<thead>\n<tr>\n<th id=\"Visual\"><strong>PROJECT <\/strong><\/th>\n<th><strong>SPONSOR <\/strong><\/th>\n<th><strong>PRINCIPAL INVESTIGATOR <\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Health Disparities in the Development, Persistence, and Progression of Uveitis and Ocular Inflammation in the United States<\/td>\n<td>NIH\/NEI<\/td>\n<td>Brian Toy, MD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/section>\n<h3>Visual Processing<\/h3>\n<section tabindex=\"0\">\n<div class=\"table-2\">\n<table width=\"100%\">\n<thead>\n<tr>\n<th><strong>PROJECT <\/strong><\/th>\n<th><strong>SPONSOR <\/strong><\/th>\n<th><strong>PRINCIPAL INVESTIGATOR <\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td id=\"Other\">Analyses of Retinal Circuits after Rod Rescue in a Mouse Model of Human Blindness<\/td>\n<td>NIH\/NEI<\/td>\n<td>Jeannie Chen, PhD (Physiology and Neuroscience)<\/td>\n<\/tr>\n<tr>\n<td>Development and Maintenance of the Human Photoreceptor-Bipolar Cell Synapse<\/td>\n<td>NIH\/NEI<\/td>\n<td>Aaron Nagiel, MD, PhD<\/td>\n<\/tr>\n<tr>\n<td>Processing and transformation of visual signals in the superior colliculus<\/td>\n<td>NIH\/NEI<\/td>\n<td>Huizhong Tao, PhD (Physiology and Neuroscience)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/section>\n<h3>Other<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\">Project<\/td>\n<td style=\"width: 33.3333%;\">Sponsor<\/td>\n<td style=\"width: 33.3333%;\">Principal Investigator<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Development of a novel tear-based biomarker assay for diagnosis of Parkinson&#8217;s disease using RT-QuIC<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Sarah Hamm-Alvarez, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">The Cost Effectiveness and Value of Treating Combat Ocular Trauma<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">DoD<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Mark Humayun, MD, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">ENIGMA World Aging Center<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Identifying brain networks to predict treatment resistance and post-surgical outcome: An ENIGMA-Epilepsy initiative<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NINDS<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">ENIGMA Bipolar Initiative: A Global Study of Imaging Genomics &amp; Clinical Outcomes<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIHMS<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Redefine Trans-Neuropsychiatric Disorder Brain Patterns through Big-Data and Machine Learning<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIHMS<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease Biobanks<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">ENIGMA Parkinson\u2019s Initiative: A Global Initiative for Parkinson\u2019s Disease<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NINDS<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">ENIGMA-SD: Understanding Sex Differences in Global Mental Health through ENIGMA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIHMS<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">FiberNET: Deep learning to evaluate brain tract integrity worldwide and in AD<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Human Newborn Energy Homeostasis Brain Networks And Infant Adiposity<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIDDK<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Laboratory of Neuro Imaging Resource (LONIR)<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIBIB<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Paul Thompson, PhD; Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Alzheimer Disease Research Center<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Vascular Contributions to Dementia and Genetic Risk Factors for Alzheimer&#8217;s Disease<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Health and Aging Brain among Latino Elders (HABLE-AT(N)) Study<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Neurocognitive Aging &amp; Analytics Research Education (NAARE)<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Training for the Multiscale and Multimodal Analysis of Biomarkers in Alzheimer&#8217;s Disease<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NINDS<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Data Archive for the Brain Initiative (DABI)<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIHMS<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Health Disparities in Alzheimer&#8217;s Disease and Mild Cognitive Impairment among Mexican Americans<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Alzheimer&#8217;s Disease Sequencing Project Phenotype Harmonization Consortium<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Effects of physical activity on brain function and network connectivity in MCI<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NIA<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Arthur Toga, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">Large aperture and wideband modular ultrasound arrays for the diagnosis of liver cancer<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NCI<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Qifa Zhou, PhD<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px; width: 33.3333%;\">High Resolution Ultrasound in Interventional Radiology<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">NIH\/NCI<\/td>\n<td style=\"height: 24px; width: 33.3333%;\">Qifa Zhou, PhD<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<section tabindex=\"0\">\n<div class=\"table-2\"><\/div>\n<\/section>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n    \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--featured-block white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          Learn More\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p><span style=\"font-weight: 400;\">For an overview of our five research focus areas, visit the Research main page. For individual PI laboratory descriptions, visit Research Laboratories.<\/span><\/p>\n\n\n\n<\/div>\n      \n              <div class=\"links-container\">\n                          \n<div class=\"f--field f--link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/\"\n    >\n    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"20\" height=\"12\" viewBox=\"0 0 20 12\"><polygon points=\"14 0 20 6 19 7 19 7 19 7 14 12 13 10.9 16.9 7 0 7 0 5 17 5 13 1 14 0\" fill-rule=\"evenodd\" stroke-width=\"0\"\/><\/svg>    Research\n    <\/a>\n\n\n<\/div>\n                          \n<div class=\"f--field f--link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/laboratories\/\"\n    >\n    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"20\" height=\"12\" viewBox=\"0 0 20 12\"><polygon points=\"14 0 20 6 19 7 19 7 19 7 14 12 13 10.9 16.9 7 0 7 0 5 17 5 13 1 14 0\" fill-rule=\"evenodd\" stroke-width=\"0\"\/><\/svg>    Research Laboratories\n    <\/a>\n\n\n<\/div>\n                  <\/div>\n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/ophthalmology\/wp-content\/uploads\/sites\/6\/2026\/06\/KSOM_square.png\"\n          data-srcset=\"https:\/\/keck.usc.edu\/ophthalmology\/wp-content\/uploads\/sites\/6\/2026\/06\/KSOM_square.png 768w\"          data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"The Keck School Quad\"\n        \n                \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":12,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-61","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - 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