{"id":62,"date":"2023-08-02T22:55:15","date_gmt":"2023-08-02T22:55:15","guid":{"rendered":"https:\/\/keck.usc.edu\/ophthalmology\/?page_id=62"},"modified":"2026-02-20T19:50:58","modified_gmt":"2026-02-20T19:50:58","slug":"clinical-trials","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/ophthalmology\/research\/clinical-trials\/","title":{"rendered":"Clinical Trials"},"content":{"rendered":"\n\n\n\n\n  \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"\/ophthalmology\/\"  aria-label=\"Read more about Department of Ophthalmology\">Department of Ophthalmology<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n  <h1>Clinical Trials<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"http:\/\/keckmedicine.org\/eye\"\n  target=\"_blank\"  aria-label=\"Read&#x20;more&#x20;about&#x20;Are&#x20;you&#x20;a&#x20;patient&#x3F;\">\n        Are you a patient?\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                                  In This Section\n                                <svg class=\"menu\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\"\n                  y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#000\" d=\"M4,23h3v3H4V23z M4,16h3v3H4V16z M10,23\n                  h21v3H10V23z M10,16h21v3H10V16z M10,9h21v3H10V9z M4,9h3v3H4V9z\"\/>\n                <\/svg>\n\n                <svg class=\"close\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\"\n                  viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <polygon fill=\"#000\" fill-rule=\"evenodd\" clip-rule=\"evenodd\" points=\"26,10.4 24.6,9 17.5,16.1 10.4,9 9,10.4 16.1,17.5\n                  9,24.6 10.4,26 17.5,18.9 24.6,26 26,24.6 18.9,17.5 \"\/>\n                <\/svg>\n              <\/button>\n\n              <nav\n  class=\"mc--menu mc--\"\n  >\n  <ul class=\"m--menu m--\">\n    \n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-home menu-item-24 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/\" >Ophthalmology<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Ophthalmology\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-411\">\n      <a 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6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-71\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/sponsored-research\/\" >Sponsored Research<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-263\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/center-core-for-vision-research\/\" >Center Core for Vision Research<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-72\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/clinical-trials\/\" >Clinical Trials<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-74\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/publications\/\" >Publications<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-76\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/funding-opportunities\/\" >Funding Opportunities<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-73\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/research\/laboratories\/\" >Laboratories<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-20 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/\" >Training &amp; Education<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Training &amp; Education\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-22 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/residency-program\/\" >Residency Program<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Residency Program\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-97\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/residency-program\/application-process\/\" >Application Process<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-98\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/residency-program\/current-residents\/\" >Current Residents<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-99\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/residency-program\/curriculum\/\" >Curriculum<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-100\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/residency-program\/faq\/\" >FAQ<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-84\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/residency-program\/leadership\/\" >Residency Leadership<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n                      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-21 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/\" >Fellowship Program<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Fellowship Program\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-168\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/cornea-external-disease-fellowship\/\" >Cornea, External Diseases &amp; Refractive Surgery<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-169\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/glaucoma-fellowship\/\" >Glaucoma Fellowship<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-170\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/neuro-ophthalmology\/\" >Neuro-Ophthalmology<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-172\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/pediatric-ophthalmology-and-strabismus\/\" >Pediatric Ophthalmology and Strabismus<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-173\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/vitreoretinal-surgery\/\" >Vitreoretinal Surgery<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-174\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/training-education\/fellowship-program\/current-fellows\/\" >Current Fellows<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-19\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/patient-care\/\" >Patient Care<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-96\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/faculty\/\" >Faculty<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-87\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/support-2\/\" >Support<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-89\">\n      <a href=\"https:\/\/keck.usc.edu\/ophthalmology\/contact-2\/\" >Contact<\/a>\n  \n  \n<\/li>\n\n    \n      <\/ul><!-- m--menu -->\n<\/nav>\n\n            <\/div>\n                  <\/div>\n        <\/div>\n\n\n  <\/div><\/div>\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--spacer \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--spacer\"\n    \n      >\n\n    \n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Here at the USC Roski Eye Institute, we offer patients the opportunity to participate in clinical trials and research. Please see our active clinical trials below. Contact our clinical research coordinators for opportunities that may be suitable for you.<\/p>\n<div class=\"table-2\">\n<table style=\"height: 503px; width: 100%;\" width=\"100%\">\n<thead>\n<tr style=\"height: 47px;\">\n<th style=\"height: 47px; width: 12.78%;\" align=\"left\">Protocol<\/th>\n<th style=\"height: 47px; width: 38.6832%;\" align=\"left\">Study Title<\/th>\n<th style=\"width: 22.5202%; text-align: left; height: 47px;\">Principal Investigator<\/th>\n<th style=\"height: 47px; width: 24.699%;\" align=\"left\">Link to Clinical Trials<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"height: 143px;\">\n<td style=\"height: 143px; width: 12.78%;\" align=\"left\">NAC Attack<\/td>\n<td style=\"height: 143px; width: 38.6832%;\" align=\"left\">A Phase-3, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients with Retinitis Pigmentosa<\/td>\n<td style=\"width: 22.5202%; height: 143px;\">Dr. Hossein Ameri<\/td>\n<td style=\"height: 143px; width: 24.699%;\" align=\"left\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05537220?lat=34.0223519&amp;lng=-118.285117&amp;locStr=University%20of%20Southern%20California,%20Los%20Angeles,%20CA&amp;distance=50&amp;cond=Retinitis%20Pigmentosa&amp;rank=1\" target=\"_blank\" rel=\"noopener\">Study Details | NAC Attack | ClinicalTrials.gov<\/a><\/td>\n<\/tr>\n<tr style=\"height: 143px;\">\n<td style=\"width: 12.78%; height: 143px;\" width=\"124\">PHOENIX<\/td>\n<td style=\"width: 38.6832%; height: 143px;\" width=\"358\">Phase 3, Multicenter, RandOmized, Double-masked, PlacEbo-CoNtrolled Study of TInlarebant to EXplore Safety and Efficacy in the Treatment of Geographic Atrophy<\/td>\n<td style=\"width: 22.5202%; height: 143px;\" width=\"251\">Dr. Hossein Ameri<\/td>\n<td style=\"width: 24.699%; height: 143px;\" width=\"323\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05949593?cond=Geographic%20Atrophy&amp;term=belite&amp;rank=1\" target=\"_blank\" rel=\"noopener\">Study Details | Phoenix | ClinicalTrials.gov<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 12.78%;\">OCU400<\/td>\n<td style=\"width: 38.6832%;\">A phase 3, multi-center, randomized study to assess the efficacy and safety of subretinal<br \/>\nOCU400 gene therapy compared to untreated control for the treatment of Retinitis Pigmentosa<\/td>\n<td style=\"width: 22.5202%;\">Dr. Hossein Ameri<\/td>\n<td style=\"width: 24.699%;\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06388200?cond=Retinitis%20Pigmentosa&amp;rank=10\" target=\"_blank\" rel=\"noopener\">Study Details | OCU400 | ClinicalTrials.gov\u00a0<\/a><\/td>\n<\/tr>\n<tr style=\"height: 170px;\">\n<td style=\"width: 12.78%; height: 170px;\" width=\"124\">Clarity<\/td>\n<td style=\"width: 38.6832%; height: 170px;\" width=\"358\">A Phase 3 Randomized, Double-Masked, Placebo-Controlled Study to Investigate the Safety and Efficacy of Oral Brepocitinib in Adults with Active, Non-Infectious Intermediate-, Posterior-,<br \/>\nand Panuveitis<\/td>\n<td style=\"width: 22.5202%; height: 170px;\" width=\"251\">Dr. Brian Toy<\/td>\n<td style=\"width: 24.699%; height: 170px;\" width=\"323\"><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06431373\" target=\"_blank\" rel=\"noopener\">Study Details | Clarity | ClinicalTrials.gov\u00a0<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h3>Contact Information:<\/h3>\n<p><strong>Research Coordinator<\/strong>: Mariana Edwards<br \/>\nP: (323) 442-6490<br \/>\nE: <a href=\"mailto:mariana.edwards@med.usc.edu\">mariana.edwards@med.usc.edu<\/a><\/p>\n<p><strong>Research Coordinator<\/strong>: Kimberly Rodriguez<br \/>\nP: (323) 865-6824<br \/>\nE: <a href=\"mailto:Kimberly.Rodriguez2@med.usc.edu\">Kimberly.Rodriguez2@med.usc.edu<\/a><\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":12,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-62","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - 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