Clinical Research 2017-09-14T16:04:57+00:00

Clinical Research


Advancing the musculoskeletal field using multidisciplinary, evidence-based research

The Department of Orthopaedic Surgery continues to pioneer major advances in the care and treatment of musculoskeletal injuries and disorders.

Adult Joint/Total Joint Arthroplasty

Jay Lieberman, MD, focuses his clinical research on improving outcomes after total joint arthroplasty. He uses large administrative databases to analyze total hip and knee arthroplasty patients and patients with osteonecrosis of the hip. His latest research projects relate to enhancing venous thromboembolism prophylaxis after total joint replacement, assessing the cost effectiveness of preoperative management of total knee arthroplasty and unicondylar knee arthroplasty patients. Lieberman is a pioneer in the development of regional gene therapy strategy to enhance bone repair for complex fractures and revision total joint arthroplasty patients.

Lawrence Dorr, MD, focuses his research on the use of computer navigation to improve the accuracy of component placement in total joint arthroplasty. He is also evaluating the anatomic variants in hip anatomy that influence the development of osteoarthritis and investigating the influence of the spine and pelvis position on wear in total joint replacement. Dr. Dorr is assessing virtual reality modeling of the skeleton to evaluate the influence of motion on hip replacement to determine the optimal position for the implants.


Alidad Ghiassi, MD and Milan Stevanovic, MD are conducting anatomic studies in wrist fractures to assess the optimum modes of stabilization of distal radius and scaphoid fractures. They are also investigating the utility of ultrasound in percutaneous trigger digit release and working to improve modes of rehabilitation for patients suffering wrist fractures.

Hip and Knee

Donald B. Longjohn, MD, conducts clinical and biomechanical studies involving hip and knee replacement implants and techniques. His current work also includes a study regarding the use of biologic agents to prevent bone loss around hip replacement.

Sports Medicine

Reza Omid, MD, works to improve treatment options for shoulder and elbow disorders. He is currently developing techniques using a new tendon transfer to aid patients with irreparable rotator cuff tears. He is also exploring the effects of tendon transfers on the reverse total shoulder arthroplasty stability.

The research of James Tibone, MD, includes evaluating the anatomic factors that influence shoulder instability and rotator cuff tears. A recent project measured vitamin D levels in student athletes.

Dr. C. Thomas Vangsness is participating in a clinical trial to assess the potential of stem cells to induce cartilage repair.

Clinical Research Facilities

The department’s faculty, fellows, residents and students have access to a broad and diverse patient population throughout Los Angeles County. We conduct a variety of clinical research projects in tandem with patient care at five primary facilities:

  • Keck Hospital of USC
  • Children’s Hospital Los Angeles
  • Kaiser-Permanente Baldwin Park
  • Los Angeles County+USC Medical Center
  • Rancho Los Amigos National Rehabilitation Center

The department also has basic science research lab space in the Hoffman Medical Research Building on the USC Health Sciences Campus.