Florence M Hofman, PhD
Florence M Hofman, PhD
Professor of Pathology
HMR 2011 Zonal Ave Health Sciences Campus Los Angeles
Dr. Hofman's field of expertise is angiogenesis and the blood-brain-barrier in human primary brain tumors and metastatic breast cancer to the brain. Her approach is to functionally characterize the tumor-associated brain endothelial cells because these cells are the target for anti-vascular therapy in cancer. Her laboratory uses both in vitro and in vivo systems to determine the mechanism(s) of chemoresistance. Once it is understood why these cells are resistant to standard of care drugs, they will identify agents which specifically disrupt the tumor vasculature, resulting in eliminating tumor growth.

NEO212: sub-cytotoxic doses capable of inhibiting glioma stem cell invasion Oncoscience. 2018 May; 5(5-6):148-149. . View in PubMed

Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model J Neurosurg. 2018 Mar; 128(3):695-700. . View in PubMed

NEO212 Inhibits Migration and Invasion of Glioma Stem Cells Mol Cancer Ther. 2018 Mar; 17(3):625-637. . View in PubMed

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram Int J Mol Sci. 2018 Jan 17; 19(1). . View in PubMed

A perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells Cancer Lett. 2017 08 01; 400:161-174. . View in PubMed

Monoamine oxidase A (MAO A) inhibitors decrease glioma progression Oncotarget. 2016 Mar 22; 7(12):13842-53. . View in PubMed

A novel drug conjugate, NEO212, targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells Cancer Lett. 2016 Feb 28; 371(2):240-50. . View in PubMed

Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90a) to Survive a Hostile Hypoxic Environment Sci Rep. 2016 Feb 05; 6:20605. . View in PubMed

Tumor vasculature and glioma stem cells: Contributions to glioma progression Cancer Lett. 2016 10 01; 380(2):545-51. . View in PubMed

Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and a6ß1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties Front Cell Neurosci. 2016; 10:284. . View in PubMed

Nanoparticle biointerfacing by platelet membrane cloaking Nature. 2015 Oct 01; 526(7571):118-21. . View in PubMed

Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo J Biomed Sci. 2015 Aug 19; 22:71. . View in PubMed

First clinical results of a personalized immunotherapeutic vaccine against recurrent, incompletely resected, treatment-resistant glioblastoma multiforme (GBM) tumors, based on combined allo- and auto-immune tumor reactivity Vaccine. 2015 May 28; 33(23):2690-6. . View in PubMed

A novel temozolomide analog, NEO212, with enhanced activity against MGMT-positive melanoma in vitro and in vivo Cancer Lett. 2015 Mar 28; 358(2):144-151. . View in PubMed

Quinoline-based antimalarial drugs: a novel class of autophagy inhibitors Neurosurg Focus. 2015 Mar; 38(3):E12. . View in PubMed

Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals Neurosurg Focus. 2015 Mar; 38(3):E8. . View in PubMed

Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model Hum Gene Ther. 2015 Feb; 26(2):82-93. . View in PubMed

Use of ERC-1671 Vaccine in a Patient with Recurrent Glioblastoma Multiforme after Progression during Bevacizumab Therapy: First Published Report Perm J. 2015; 19(2):41-6. . View in PubMed

Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy Neurosurg Focus. 2014 Dec; 37(6):E12. . View in PubMed

NEO212, temozolomide conjugated to perillyl alcohol, is a novel drug for effective treatment of a broad range of temozolomide-resistant gliomas Mol Cancer Ther. 2014 Aug; 13(8):2004-17. . View in PubMed

Argonaute-2 promotes miR-18a entry in human brain endothelial cells J Am Heart Assoc. 2014 May 16; 3(3):e000968. . View in PubMed

A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo Mol Cancer Ther. 2014 May; 13(5):1181-93. . View in PubMed

A systematic review of inhaled intranasal therapy for central nervous system neoplasms: an emerging therapeutic option J Neurooncol. 2014 Feb; 116(3):437-46. . View in PubMed

Sequential administration of carbon nanotubes and near-infrared radiation for the treatment of gliomas Front Oncol. 2014; 4:180. . View in PubMed

MicroRNA-18a improves human cerebral arteriovenous malformation endothelial cell function Stroke. 2014 Jan; 45(1):293-7. . View in PubMed

ImmunohistochemistryCurr Protoc Immunol. 2013 Nov 18; 103:Unit 21. 4. . View in PubMed

Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I PLoS One. 2013; 8(6):e65695. . View in PubMed

Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent Cancer Lett. 2012 Dec 30; 326(2):143-54. . View in PubMed

Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors Cancer Lett. 2012 Dec 01; 325(1):63-71. . View in PubMed

Perillyl alcohol for the treatment of temozolomide-resistant gliomas Mol Cancer Ther. 2012 Nov; 11(11):2462-72. . View in PubMed

Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation Oncoimmunology. 2012 May 01; 1(3):298-305. . View in PubMed

Exploring the Therapeutic Efficacy of Glioma Vaccines Based on Allo- and Syngeneic Antigens and Distinct Immunological Costimulation Activators J Clin Cell Immunol. 2012; Suppl 5:004. . View in PubMed

Noscapine inhibits tumor growth in TMZ-resistant gliomas Cancer Lett. 2011 Dec 22; 312(2):245-52. . View in PubMed

Thrombospondin-1 modulates the angiogenic phenotype of human cerebral arteriovenous malformation endothelial cells Neurosurgery. 2011 May; 68(5):1342-53; discussion 1353. . View in PubMed

A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis Cancer Res. 2011 Apr 15; 71(8):2848-57. . View in PubMed

Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models Cancer Lett. 2011 Mar 28; 302(2):100-8. . View in PubMed

Effective conversion of irinotecan to SN-38 after intratumoral drug delivery to an intracranial murine glioma model in vivoLaboratory investigation. J Neurosurg. 2011 Mar; 114(3):689-94. . View in PubMed

Preclinical development of novel anti-glioma drugs targeting the endoplasmic reticulum stress response Curr Pharm Des. 2011; 17(23):2428-38. . View in PubMed

Immunotherapy of malignant gliomas using autologous and allogeneic tissue cells Anticancer Agents Med Chem. 2010 Jul; 10(6):462-70. . View in PubMed

Antiangiogenic activities of 2,5-dimethyl-celecoxib on the tumor vasculature Mol Cancer Ther. 2010 Mar; 9(3):631-41. . View in PubMed

Glioma-associated endothelial cells are chemoresistant to temozolomide J Neurooncol. 2009 Oct; 95(1):13-22. . View in PubMed

Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress Cancer Lett. 2009 Sep 08; 282(1):87-97. . View in PubMed

Optic neuritis in different strains of mice by a recombinant HSV-1 expressing murine interleukin-2 Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3275-82. . View in PubMed

Aberrant angiogenic characteristics of human brain arteriovenous malformation endothelial cells Neurosurgery. 2009 Jan; 64(1):139-46; discussion 146-8. . View in PubMed

Increased survivin expression confers chemoresistance to tumor-associated endothelial cells Am J Pathol. 2008 Aug; 173(2):575-85. . View in PubMed

Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells Mol Cancer Res. 2008 Aug; 6(8):1268-75. . View in PubMed

Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs Expert Opin Investig Drugs. 2008 Feb; 17(2):197-208. . View in PubMed

Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib Cancer Res. 2008 Feb 01; 68(3):843-51. . View in PubMed

Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development Cancer Res. 2008 Jan 15; 68(2):498-505. . View in PubMed

The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas Cancer Res. 2007 Oct 15; 67(20):9809-16. . View in PubMed

Reduced survivin expression and tumor cell survival during chronic hypoxia and further cytotoxic enhancement by the cyclooxygenase-2 inhibitor celecoxib J Biomed Sci. 2007 Sep; 14(5):647-62. . View in PubMed

Both virus and tumor necrosis factor alpha are critical for endothelium damage in a mouse model of dengue virus-induced hemorrhage J Virol. 2007 Jun; 81(11):5518-26. . View in PubMed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion J Leukoc Biol. 2007 May; 81(5):1205-12. . View in PubMed

Glioma-associated endothelial cells show evidence of replicative senescence Exp Cell Res. 2007 Apr 01; 313(6):1192-202. . View in PubMed

Irinotecan: a potential new chemotherapeutic agent for atypical or malignant meningiomas J Neurosurg. 2007 Mar; 106(3):455-62. . View in PubMed

Multiple signaling pathways are involved in endothelin-1-induced brain endothelial cell migration Am J Physiol Cell Physiol. 2006 Jul; 291(1):C155-64. . View in PubMed

Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo Mol Cancer. 2006 May 18; 5:19. . View in PubMed

Characteristics of tumor-associated endothelial cells derived from glioblastoma multiforme Neurosurg Focus. 2006 Apr 15; 20(4):E22. . View in PubMed

Fibroblast growth factor-2-retargeted adenoviral vector for selective transduction of primary glioblastoma multiforme endothelial cells Neurosurg Focus. 2006 Apr 15; 20(4):E26. . View in PubMed

Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin Neurosurg Focus. 2006 Apr 15; 20(4):E20. . View in PubMed

Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib Blood. 2005 Dec 15; 106(13):4330-8. . View in PubMed

Interleukin-8 differentially regulates migration of tumor-associated and normal human brain endothelial cells Cancer Res. 2005 Nov 15; 65(22):10347-54. . View in PubMed

Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease Nat Med. 2005 Sep; 11(9):959-65. . View in PubMed

Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo Cancer Biol Ther. 2005 May; 4(5):571-82. . View in PubMed

CD8+-dependent CNS demyelination following ocular infection of mice with a recombinant HSV-1 expressing murine IL-2 Exp Neurol. 2005 May; 193(1):1-18. . View in PubMed

T cell expansion is regulated by activated Gr-1+ splenocytes Cell Immunol. 2005 May; 235(1):39-45. . View in PubMed

Functional and phenotypic differences between glioblastoma multiforme-derived and normal human brain endothelial cells J Neurosurg. 2005 Apr; 102(4):699-705. . View in PubMed

Involvement of CD8+ T-cells in exacerbation of corneal scarring in mice Curr Eye Res. 2004 Aug-Sep; 29(2-3):145-51. . View in PubMed

Extra-cellular superoxide promotes T cell expansion through inactivation of nitric oxide J Neuroimmunol. 2004 Aug; 153(1-2):183-9. . View in PubMed

Tissue expression of inducible nitric oxide synthase requires IFN-gamma production by infiltrating splenic T cells: more evidence for immunosuppression by nitric oxide J Neuroimmunol. 2003 Dec; 145(1-2):86-90. . View in PubMed

A simple method for isolation and characterization of mouse brain microvascular endothelial cells J Neurosci Methods. 2003 Nov 30; 130(1):53-63. . View in PubMed

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain Nat Med. 2003 Jul; 9(7):907-13. . View in PubMed

Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium Am J Physiol Cell Physiol. 2002 Sep; 283(3):C895-904. . View in PubMed

ImmunohistochemistryCurr Protoc Immunol. 2002 Aug; Chapter 21:Unit 21. 4. . View in PubMed

The type IV phosphodiesterase inhibitor rolipram induces expression of the cell cycle inhibitors p21(Cip1) and p27(Kip1), resulting in growth inhibition, increased differentiation, and subsequent apoptosis of malignant A-172 glioma cells Cancer Biol Ther. 2002 May-Jun; 1(3):268-76. . View in PubMed

Cell cycle phase-specific survival of CD95 ligand-challenged Jurkat cells: upregulation of heat-shock response Cell Immunol. 2001 Jul 10; 211(1):21-9. . View in PubMed

Endothelin-1 and monocyte chemoattractant protein-1 modulation in ischemia and human brain-derived endothelial cell cultures J Neuroimmunol. 2001 May 01; 116(1):62-73. . View in PubMed

Antigen presentation to Th1 but not Th2 cells by macrophages results in nitric oxide production and inhibition of T cell proliferation: interferon-gamma is essential but insufficient Cell Immunol. 2000 Dec 15; 206(2):125-35. . View in PubMed

Corneal macrophage infiltrates following ocular herpes simplex virus type 1 challenge vary in BALB/c mice vaccinated with different vaccines Vaccine. 2000 Dec 08; 19(9-10):1266-73. . View in PubMed

Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice J Immunol. 2000 May 15; 164(10):5177-83. . View in PubMed

Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript Science. 2000 Feb 25; 287(5457):1500-3. . View in PubMed

Endothelin-1-induced interleukin-8 production in human brain-derived endothelial cells is mediated by the protein kinase C and protein tyrosine kinase pathways Blood. 1999 Aug 15; 94(4):1291-9. . View in PubMed

Endothelin-1 enhances plasminogen activator inhibitor-1 production by human brain endothelial cells via protein kinase C-dependent pathway Arterioscler Thromb Vasc Biol. 1999 Jul; 19(7):1768-75. . View in PubMed

Specific and nonspecific immune stimulation of MHC-II-deficient mice results in chronic HSV-1 infection of the trigeminal ganglia following ocular challenge Virology. 1999 Jun 05; 258(2):208-16. . View in PubMed

Vaccination with different HSV-1 glycoproteins induces different patterns of ocular cytokine responses following HSV-1 challenge of vaccinated mice Vaccine. 1999 Jun 04; 17(20-21):2576-82. . View in PubMed

Nicotine increases plasminogen activator inhibitor-1 production by human brain endothelial cells via protein kinase C-associated pathway Stroke. 1999 Mar; 30(3):651-5. . View in PubMed

HIV-1 tat protein induces the production of interleukin-8 by human brain-derived endothelial cells J Neuroimmunol. 1999 Feb 01; 94(1-2):28-39. . View in PubMed

The role of neutralizing antibody and T-helper subtypes in protection and pathogenesis of vaccinated mice following ocular HSV-1 challenge Immunology. 1998 Nov; 95(3):352-9. . View in PubMed

Endothelin-1 induces production of the neutrophil chemotactic factor interleukin-8 by human brain-derived endothelial cells Blood. 1998 Nov 01; 92(9):3064-72. . View in PubMed

Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas Lab Invest. 1998 Feb; 78(2):165-74. . View in PubMed

Circulating antibody against tumor necrosis factor-alpha protects rat brain from reperfusion injury J Cereb Blood Flow Metab. 1998 Jan; 18(1):52-8. . View in PubMed

Extensive peroxynitrite activity during progressive stages of central nervous system inflammation J Neuroimmunol. 1997 Jul; 77(1):1-7. . View in PubMed

Soluble TNF-alpha receptors are constitutively shed and downregulate adhesion molecule expression in malignant gliomas J Neuropathol Exp Neurol. 1997 May; 56(5):541-50. . View in PubMed

TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells J Neuroimmunol. 1997 Mar; 73(1-2):155-61. . View in PubMed

Soluble tumor necrosis factor receptors are present in human vitreous and shed by retinal pigment epithelial cells Exp Eye Res. 1996 Sep; 63(3):311-7. . View in PubMed

Absence of a prominent Th2 cytokine response in human tuberculosis Infect Immun. 1996 Apr; 64(4):1351-6. . View in PubMed

Induction of intercellular adhesion molecule-1 by tumor necrosis factor-alpha through the 55-kDa receptor is dependent on protein kinase C in human retinal pigment epithelial cells Invest Ophthalmol Vis Sci. 1996 Mar; 37(4):597-606. . View in PubMed

Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Dec 15; 10(5):511-21. . View in PubMed

Tumor necrosis factor expression during mouse hepatitis virus-induced demyelinating encephalomyelitis J Virol. 1995 Sep; 69(9):5898-903. . View in PubMed

SV40-immortalized and primary cultured human retinal pigment epithelial cells share similar patterns of cytokine-receptor expression and cytokine responsiveness Curr Eye Res. 1995 Jun; 14(6):495-503. . View in PubMed

Local expression of tumor necrosis factor alpha and interleukin-2 correlates with protection against corneal scarring after ocular challenge of vaccinated mice with herpes simplex virus type 1 J Virol. 1995 Jan; 69(1):334-40. . View in PubMed

Cytokine expression in radiation-induced delayed cerebral injury Neurosurgery. 1994 Nov; 35(5):822-9; discussion 829-30. . View in PubMed

Exogenous tat protein activates central nervous system-derived endothelial cells J Neuroimmunol. 1994 Oct; 54(1-2):19-28. . View in PubMed

Recombination between feline exogenous and endogenous retroviral sequences generates tropism for cerebral endothelial cells Am J Pathol. 1994 Feb; 144(2):348-58. . View in PubMed

Hypothesis for autoantigen presentation and T cell activation Adv Exp Med Biol. 1994; 350:651-4. . View in PubMed

Exogenous tat protein activates human endothelial cells Blood. 1993 Nov 01; 82(9):2774-80. . View in PubMed

Differential effects of tumor necrosis factor-alpha on proliferation, cell surface antigen expression, and cytokine interactions in malignant gliomas Neurosurgery. 1993 Jan; 32(1):85-94. . View in PubMed

Early activation of splenic macrophages by tumor necrosis factor alpha is important in determining the outcome of experimental histoplasmosis in mice Infect Immun. 1992 Oct; 60(10):4230-8. . View in PubMed

Cytokines and immunoregulatory molecules in malignant glial neoplasms J Neurosurg. 1992 Aug; 77(2):265-73. . View in PubMed

Tumor necrosis factor-alpha in the retina in acquired immune deficiency syndrome Invest Ophthalmol Vis Sci. 1992 May; 33(6):1829-35. . View in PubMed

Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10PL mice. Proc Natl Acad Sci U S A. 1992 Jan 15; 89(2):574-8. . View in PubMed

Regional distribution of thrombomodulin in human brain Brain Res. 1991 Aug 09; 556(1):1-5. . View in PubMed

Class II antigen expression by lacrimal epithelial cellsAn updated working hypothesis for antigen presentation by epithelial cells. Invest Ophthalmol Vis Sci. 1991 Jul; 32(8):2302-10. . View in PubMed

Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis Clin Immunol Immunopathol. 1991 Mar; 58(3):331-42. . View in PubMed

Differential CD3/T cell antigen receptor-mediated IL-2 production in jurkat T cellsDissociation of IL-2 response from total inositol phosphate and calcium responses. J Immunol. 1990 Aug 15; 145(4):1078-87. . View in PubMed

Cytokine interactions in the central nervous system Reg Immunol. 1990-1991; 3(5):268-78. . View in PubMed

Tumor necrosis factor identified in multiple sclerosis brain J Exp Med. 1989 Aug 01; 170(2):607-12. . View in PubMed

Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions Nature. 1989 Jun 15; 339(6225):544-8. . View in PubMed

IL-4 regulates differentiation and proliferation of human precursor B cells J Immunol. 1988 Aug 15; 141(4):1185-90. . View in PubMed

In situ identification of activated Ta1+ T lymphocytes in human leprosy skin lesions Int J Lepr Other Mycobact Dis. 1987 Sep; 55(3):494-8. . View in PubMed

Immunohistology of persistent generalized lymphadenopathyEvidence for progressive lymph node abnormalities in some patients. Am J Clin Pathol. 1987 Jul; 88(1):10-9. . View in PubMed

The differentiation antigens of macrophages in human fetal liver Clin Immunol Immunopathol. 1986 Nov; 41(2):184-92. . View in PubMed

Distribution of cells bearing the Tac antigen during ontogeny of human lymphoid tissue J Immunol. 1985 Jun; 134(6):3751-5. . View in PubMed

B- and T-lymphocytes in Hodgkin's diseaseAn immunohistochemical study utilizing heterologous and monoclonal antibodies. Cancer. 1985 Feb 15; 55(4):728-37. . View in PubMed

In situ localization of T lymphocytes in disseminated coccidioidomycosis J Infect Dis. 1985 Feb; 151(2):314-9. . View in PubMed

Demonstration in situ of subsets of T-lymphocytes in sarcoidosis Am J Dermatopathol. 1984 Oct; 6(5):423-7. . View in PubMed

Heterogeneity of macrophage populations in human lymphoid tissue and peripheral blood Cell Immunol. 1984 Oct 01; 88(1):61-74. . View in PubMed

Ontogeny of B cell markers in the human fetal liver J Immunol. 1984 Sep; 133(3):1197-201. . View in PubMed

Mononuclear lymphoid populations infiltrating the microenvironment of primary CNS tumorsCharacterization of cell subsets with monoclonal antibodies. J Neurosurg. 1984 Jun; 60(6):1138-47. . View in PubMed

HLA-DR (Ia)-positive dendritic-like cells in human fetal nonlymphoid tissues Transplantation. 1984 Jun; 37(6):590-4. . View in PubMed

In situ identification of cells in human leprosy granulomas with monoclonal antibodies to interleukin 2 and its receptor J Immunol. 1984 Jun; 132(6):3085-90. . View in PubMed

Altered distribution of B and T lymphocytes in lymph-nodes from homosexual men with Kaposi's sarcoma Lancet. 1983 Oct 01; 2(8353):768-71. . View in PubMed

Analysis of B-cell antigens in normal reactive lymphoid tissue using four B-cell monoclonal antibodies Blood. 1983 Oct; 62(4):775-83. . View in PubMed

T-lymphocyte subsets in lymph nodes from homosexual men JAMA. 1983 Sep 09; 250(10):1302-5. . View in PubMed

Immunoperoxidase techniques applied to dermatopathology J Cutan Pathol. 1983 Jun; 10(3):145-63. . View in PubMed

Kaposi's sarcoma in homosexual men: an immunohistochemical study J Am Acad Dermatol. 1983 May; 8(5):620-7. . View in PubMed

Demonstration of a subpopulation of Ia+ T-helper cells in mycosis fungoides and the Sézary syndrome Am J Dermatopathol. 1983 Apr; 5(2):135-43. . View in PubMed

In situ demonstration of T lymphocyte subsets in granulomatous inflammation: leprosy, rhinoscleroma and sarcoidosis Clin Exp Immunol. 1983 Mar; 51(3):430-8. . View in PubMed

T lymphocyte subsets in the skin lesions of patients with leprosy J Am Acad Dermatol. 1983 Feb; 8(2):182-9. . View in PubMed

In situ characterization of T lymphocyte subsets in leprosy granulomas Int J Lepr Other Mycobact Dis. 1982 Sep; 50(3):361-2. . View in PubMed

Cytoplasmic as opposed to surface Ia antigens expressed on human peripheral blood lymphocytes and monocytes Clin Exp Immunol. 1982 Aug; 49(2):355-63. . View in PubMed

Expression of HLA-DR antigens in human fetal pancreas tissue Diabetes. 1982 Aug; 31 Suppl 4:23-9. . View in PubMed

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