Larry Liang Wang, MD, PhD

Research in Progress: RNA expression profile in bone and soft tissue; Undifferentiated neuroblastoma: biology and morphology and; Pediatric liver diseases .

• Comparative Clinicopathologic and Genomic Analysis of Hepatocellular Neoplasm, Not Otherwise Specified, and Hepatoblastoma Mod Pathol. 2024 Feb; 37(2):100385. . View in PubMed
• Pediatric Sertoli-Leydig Cell Tumors of the Ovary: An Integrated Study of Clinicopathological Features, Pan-cancer-Targeted Next-generation Sequencing and Chromosomal Microarray Analysis From a Single Institution Am J Surg Pathol. 2024 Feb 01; 48(2):194-203. . View in PubMed
• FGFR1 gene fusions in a subset of pediatric mesenchymal tumors: Expanding the genetic spectrum of tumors sharing histologic overlap with infantile fibrosarcoma and “NTRK-rearranged” spindle cell neoplasms Genes Chromosomes Cancer. 2023 11; 62(11):641-647. . View in PubMed
• An Integrative Morphologic and Molecular Approach for Diagnosis and Subclassification of Rhabdomyosarcoma Arch Pathol Lab Med. 2022 08 01; 146(8):953-959. . View in PubMed
• Independent Assessment of the Children’s Hepatic Tumors International Collaboration Risk Stratification for Hepatoblastoma and the Association of Tumor Histological Characteristics With Prognosis JAMA Netw Open. 2022 02 01; 5(2):e2148013. . View in PubMed
• Primary Knee Intra-articular Synovial Sarcoma in Pediatric and Adolescent Patients Pediatr Dev Pathol. 2021 Mar-Apr; 24(2):159-163. . View in PubMed
• Custom Pediatric Oncology Next-Generation Sequencing Panel Identifies Somatic Mosaicism in Archival Tissue and Enhances Targeted Clinical Care Pediatr Neurol. 2021 01; 114:55-59. . View in PubMed
• Clinicopathologic Characteristics of Late Acute Antibody-mediated Rejection in Pediatric Liver Transplantation Transplantation. 2021 09 01; 105(9):2045-2053. . View in PubMed
• Histopathologic features of alveolar capillary dysplasia with misalignment of pulmonary veins with atypical clinical presentation Cardiovasc Pathol. 2021 Jan – Feb; 50:107289. . View in PubMed
• Phox2b Immunohistochemical Staining in Detecting Enteric Neural Crest Cells in Hirschsprung Disease Pediatr Dev Pathol. 2021 Jan-Feb; 24(1):19-26. . View in PubMed
• Initiation of immunotherapy with activated natural killer cells and anti-GD2 antibody dinutuximab prior to resection of primary neuroblastoma prolongs survival in mice J Immunother Cancer. 2020 12; 8(2). . View in PubMed
• Mesenchymal folliculin is required for alveolar development: implications for cystic lung disease in Birt-Hogg-Dubé syndrome Thorax. 2020 06; 75(6):486-493. . View in PubMed
• The Clinical Management and Outcomes of Pelvic Neuroblastic Tumors J Surg Res. 2020 05; 249:8-12. . View in PubMed
• Activated Natural Killer Cells in Combination with Anti-GD2 Antibody Dinutuximab Improve Survival of Mice after Surgical Resection of Primary Neuroblastoma Clin Cancer Res. 2019 01 01; 25(1):325-333. . View in PubMed
• Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation Sci Rep. 2019 03 28; 9(1):5296. . View in PubMed
• The Use of Fetal Bronchoscopy in the Diagnosis and Management of a Suspected Obstructive Lung Mass AJP Rep. 2018 Jul; 8(3):e195-e200. . View in PubMed
• MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children’s oncology group Oncotarget. 2018 Jan 19; 9(5):6416-6432. . View in PubMed
• Inflammation, Active Fibroplasia, and End-stage Fibrosis in 172 Biliary Atresia Remnants Correlate Poorly With Age at Kasai Portoenterostomy, Visceral Heterotaxy, and Outcome Am J Surg Pathol. 2018 12; 42(12):1625-1635. . View in PubMed
• Hepatocellular malignant neoplasm, NOS: a clinicopathological study of 11 cases from a single institution Histopathology. 2017 Nov; 71(5):813-822. . View in PubMed
• Melanotic Neuroectodermal Tumor of Infancy Presenting With Fast-Growing Scrotal Swelling: A Case Report and Literature Review Pediatr Dev Pathol. 2017 Sep-Oct; 20(5):411-415. . View in PubMed
• TGFßR1 Blockade with Galunisertib (LY2157299) Enhances Anti-Neuroblastoma Activity of the Anti-GD2 Antibody Dinutuximab (ch1418) with Natural Killer Cells. Clin Cancer Res. 2017 Feb 01; 23(3):804-813. . View in PubMed
• Abdominal Actinomycosis in Children: A Case Report and Literature Review Pediatr Infect Dis J. 2017 03; 36(3):e76-e79. . View in PubMed
• Biological roles and potential applications of immune cell-derived extracellular vesicles J Extracell Vesicles. 2017; 6(1):1400370. . View in PubMed
• Glypican 3 as a Serum Marker for Hepatoblastoma Sci Rep. 2017 04 05; 7:45932. . View in PubMed
• The diagnostic and prognostic value of SALL4 in hepatoblastoma Histopathology. 2016 Nov; 69(5):822-830. . View in PubMed
• Refractory Kaposiform Hemangioendothelioma Associated with the Chromosomal Translocation t(13;16)(q14;p133). Pediatr Dev Pathol. 2016 Sep/Oct; 19(5):417-420. . View in PubMed
• Orthotopic liver transplant for multifocal lymphangioendotheliomatosis with thrombocytopenia Pediatr Transplant. 2016 May; 20(3):456-9. . View in PubMed
• Key Histopathologic Features of Liver Biopsies That Distinguish Biliary Atresia From Other Causes of Infantile Cholestasis and Their Correlation With Outcome: A Multicenter Study Am J Surg Pathol. 2016 12; 40(12):1601-1615. . View in PubMed
• Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization Am J Pathol. 2016 12; 186(12):3261-3272. . View in PubMed
• Hepatocellular carcinoma associated with tight-junction protein 2 deficiency Hepatology. 2015 Dec; 62(6):1914-6. . View in PubMed
• Quantification of glypican 3, ß-catenin and claudin-1 protein expression in hepatoblastoma and paediatric hepatocellular carcinoma by colour deconvolution Histopathology. 2015 Dec; 67(6):905-13. . View in PubMed
• Imaging Lymphoid Cell Death In Vivo During Polymicrobial Sepsis Crit Care Med. 2015 Nov; 43(11):2303-12. . View in PubMed
• Insulin-like Growth Factor 2 Gene Expression Molecularly Differentiates Pleuropulmonary Blastoma and Embryonal Rhabdomyosarcoma J Pediatr Hematol Oncol. 2015 Aug; 37(6):e356-60. . View in PubMed
• Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome J Clin Immunol. 2015 Jul; 35(5):435-8. . View in PubMed
• Is INI1-retained small cell undifferentiated histology in hepatoblastoma unfavorable? Hum Pathol. 2015 Apr; 46(4):620-4.. View in PubMed
• Age-dependent prognostic effect by Mitosis-Karyorrhexis Index in neuroblastoma: a report from the Children’s Oncology Group Pediatr Dev Pathol. 2014 Nov-Dec; 17(6):441-9. . View in PubMed
• Synchronous HIV/AIDS-related Epstein-Barr Virus-associated smooth muscle tumors in a 20-year-old female Pediatr Infect Dis J. 2014 Oct; 33(10):1055-6. . View in PubMed
• Percutaneous liver biopsy: pathologic diagnosis and complications in children J Pediatr Gastroenterol Nutr. 2013 Nov; 57(5):644-8. . View in PubMed
• Teratoid hepatoblastoma with abundant cholangioblastic component in a child with full trisomy 13 Pediatr Dev Pathol. 2013 Nov-Dec; 16(6):438-41. . View in PubMed
• Neuroblastoma of undifferentiated subtype, prognostic significance of prominent nucleolar formation, and MYC/MYCN protein expression: a report from the Children’s Oncology Group Cancer. 2013 Oct 15; 119(20):3718-26. . View in PubMed
• Inflammatory myofibroblastic tumors in childhood Pediatr Hematol Oncol. 2013 Oct; 30(7):640-5. . View in PubMed
• Simultaneous colonic adenocarcinoma and medulloblastoma in a 12-year-old with biallelic deletions in PMS2 J Pediatr. 2013 Aug; 163(2):601-3. . View in PubMed
• Subcutaneous Panniculitis-like T-cell lymphoma in two pediatric patients: an HIV-positive adolescent and a 4-month-old infant Fetal Pediatr Pathol. 2013 Jun; 32(3):175-83. . View in PubMed
• Peripheral neuroblastic tumors with genotype-phenotype discordance: a report from the Children’s Oncology Group and the International Neuroblastoma Pathology Committee Pediatr Blood Cancer. 2013 Mar; 60(3):363-70. . View in PubMed
• Tumor necrosis predicts survival following neo-adjuvant chemotherapy for hepatoblastoma Pediatr Blood Cancer. 2012 Sep; 59(3):493-8. . View in PubMed
• Pleuropulmonary blastoma: a single-institution experience J Pediatr Hematol Oncol. 2012 Jul; 34(5):e182-5. . View in PubMed
• Role of interleukin-10 in the pathogenesis of necrotizing enterocolitis Am J Surg. 2012 Apr; 203(4):428-35. . View in PubMed
• [Pathology of peripheral neuroblastic tumors] Zhonghua Bing Li Xue Za Zhi. 2012 Apr; 41(4):283-8. . View in PubMed
• P-glycoprotein induction by breast milk attenuates intestinal inflammation in experimental necrotizing enterocolitis Lab Invest. 2011 Nov; 91(11):1668-79. . View in PubMed
• Recruitment of dendritic cells is responsible for intestinal epithelial damage in the pathogenesis of necrotizing enterocolitis by Cronobacter sakazakii J Immunol. 2011 Jun 15; 186(12):7067-79. . View in PubMed
• Effects of neoadjuvant chemotherapy on hepatoblastoma: a morphologic and immunohistochemical study Am J Surg Pathol. 2010 Mar; 34(3):287-99. . View in PubMed
• Primary gastric tumors of infancy and childhood: 54-year experience at a single institution J Pediatr Surg. 2008 Aug; 43(8):1487-93. . View in PubMed

• Mascarenhas, Leo
• Warburton, David
• Lenz, Heinz-Josef
• Minoo, Parviz
• Asgharzadeh, Shahab
• Crandall, Edward
• Chi, Yueh-Yun
• Pawel, Bruce
• McMahon, Andrew
• Matsuo, Koji
• Biegel, Jaclyn
• Krailo, Mark
• Barkauskas, Donald
• Zhou, Shengmei