CBG Faculty

Anna H Wu

Anna H Wu

Professor of Preventive Medicine
Preventive Medicine
NOR 4443 1441 Eastlake Avenue Health Sciences Campus Los Angeles

Association between ambient air pollution and breast cancer risk: The multiethnic cohort study Int J Cancer. 2020 02 01; 146(3):699-711. . View in PubMed

Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer Hum Genet. 2019 Jul; 138(7):789-791. . View in PubMed

A Pooled Analysis of Breastfeeding and Breast Cancer Risk by Hormone Receptor Status in Parous Hispanic Women Epidemiology. 2019 05; 30(3):449-457. . View in PubMed

Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women Cancer Med. 2019 05; 8(5):2503-2513. . View in PubMed

Discovery of common and rare genetic risk variants for colorectal cancer Nat Genet. 2019 01; 51(1):76-87. . View in PubMed

A comprehensive gene-environment interaction analysis in Ovarian Cancer using genome-wide significant common variants Int J Cancer. 2019 05 01; 144(9):2192-2205. . View in PubMed

Association between genetically predicted polycystic ovary syndrome and ovarian cancer: a Mendelian randomization study Int J Epidemiol. 2019 06 01; 48(3):822-830. . View in PubMed

Evaluation of Medicare Claims Data as a Tool to Identify Dementia J Alzheimers Dis. 2019; 67(2):769-778. . View in PubMed

Body mass index, comorbidities, and hormonal factors in relation to meningioma in an ethnically diverse population: the Multiethnic Cohort Neuro Oncol. 2019 03 18; 21(4):498-507. . View in PubMed

Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study Br J Cancer. 2018 04; 118(8):1123-1129. . View in PubMed

Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic VariantsGastroenterology. 2018 04; 154(5):1273-1281. e3. . View in PubMed

Determinants of prolactin in postmenopausal Chinese women in Singapore Cancer Causes Control. 2018 01; 29(1):51-62. . View in PubMed

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk Cancer Res. 2018 09 15; 78(18):5419-5430. . View in PubMed

A Randomized Controlled Trial of Green Tea Extract Supplementation and Mammographic Density in Postmenopausal Women at Increased Risk of Breast Cancer Cancer Prev Res (Phila). 2017 Dec; 10(12):710-718. . View in PubMed

Effect of Green Tea Supplements on Liver Enzyme Elevation: Results from a Randomized Intervention Study in the United States Cancer Prev Res (Phila). 2017 Oct; 10(10):571-579. . View in PubMed

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci Br J Cancer. 2017 Feb 14; 116(4):524-535. . View in PubMed

Estrogen receptor-beta genetic variations and overall survival in patients with locally advanced gastric cancer Pharmacogenomics J. 2017 01; 17(1):36-41. . View in PubMed

A pooled analysis of dietary sugar/carbohydrate intake and esophageal and gastric cardia adenocarcinoma incidence and survival in the USA Int J Epidemiol. 2017 12 01; 46(6):1836-1846. . View in PubMed

Association analysis identifies 65 new breast cancer risk loci Nature. 2017 11 02; 551(7678):92-94. . View in PubMed

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer Cancer Res. 2017 06 01; 77(11):2789-2799. . View in PubMed

Evaluating genetic variants associated with breast cancer risk in high and moderate-penetrance genes in Asians Carcinogenesis. 2017 05 01; 38(5):511-518. . View in PubMed

Cigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies Int J Cancer. 2017 06 01; 140(11):2422-2435. . View in PubMed

A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer Int J Cancer. 2016 Dec 15; 139(12):2646-2654. . View in PubMed

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation Am J Hum Genet. 2016 Oct 06; 99(4):903-911. . View in PubMed

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer Int J Cancer. 2016 Sep 15; 139(6):1303-1317. . View in PubMed

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 Nat Genet. 2016 Apr; 48(4):374-86. . View in PubMed

A targeted genetic association study of epithelial ovarian cancer susceptibility Oncotarget. 2016 Feb 16; 7(7):7381-9. . View in PubMed

Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial Am J Clin Nutr. 2016 12; 104(6):1671-1682. . View in PubMed

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study Int J Epidemiol. 2016 10; 45(5):1619-1630. . View in PubMed

Environmental Determinants of Aggression in Adolescents: Role of Urban Neighborhood Greenspace J Am Acad Child Adolesc Psychiatry. 2016 07; 55(7):591-601. . View in PubMed

Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium Cancer Epidemiol Biomarkers Prev. 2016 07; 25(7):1114-24. . View in PubMed

Assessing the genetic architecture of epithelial ovarian cancer histological subtypes Hum Genet. 2016 07; 135(7):741-56. . View in PubMed

Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study Int J Epidemiol. 2016 06; 45(3):884-95. . View in PubMed

Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors Cancer Epidemiol Biomarkers Prev. 2016 05; 25(5):780-90. . View in PubMed

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk Obstet Gynecol. 2016 05; 127(5):828-36. . View in PubMed

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs) Sci Rep. 2016 09 07; 6:32512. . View in PubMed

Age-specific risk factor profiles of adenocarcinomas of the esophagus: A pooled analysis from the international BEACON consortium Int J Cancer. 2016 Jan 01; 138(1):55-64. . View in PubMed

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer Oncotarget. 2016 10 25; 7(43):69097-69110. . View in PubMed

An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression Hum Mol Genet. 2016 09 01; 25(17):3863-3876. . View in PubMed

Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk Hum Mol Genet. 2016 08 15; 25(16):3600-3612. . View in PubMed

Fine-Mapping of the 1p112 Breast Cancer Susceptibility Locus. PLoS One. 2016; 11(8):e0160316. . View in PubMed

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk Genet Epidemiol. 2015 Dec; 39(8):689-97. . View in PubMed

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer Carcinogenesis. 2015 Nov; 36(11):1341-53. . View in PubMed

A newly identified susceptibility locus near FOXP1 modifies the association of gastroesophageal reflux with Barrett's esophagus Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1739-47. . View in PubMed

Double-Blind Randomized 12-Month Soy Intervention Had No Effects on Breast MRI Fibroglandular Tissue Density or Mammographic Density Cancer Prev Res (Phila). 2015 Oct; 8(10):942-51. . View in PubMed

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer Nat Commun. 2015 Sep 22; 6:8234. . View in PubMed

Contribution of the neighborhood environment and obesity to breast cancer survival: the California Breast Cancer Survivorship Consortium Cancer Epidemiol Biomarkers Prev. 2015 Aug; 24(8):1282-90. . View in PubMed

African Americans and Hispanics Remain at Lower Risk of Ovarian Cancer Than Non-Hispanic Whites after Considering Nongenetic Risk Factors and Oophorectomy Rates Cancer Epidemiol Biomarkers Prev. 2015 Jul; 24(7):1094-100. . View in PubMed

Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition . 2015 Jun; 14(6):1495-503. . View in PubMed

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q312. Hum Mol Genet. 2015 May 15; 24(10):2966-84. . View in PubMed

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study Gynecol Oncol. 2015 Mar; 136(3):542-8. . View in PubMed

Diabetes and other comorbidities in breast cancer survival by race/ethnicity: the California Breast Cancer Survivorship Consortium (CBCSC) Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):361-8. . View in PubMed

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC) J Genet Genome Res. 2015; 2(2). . View in PubMed

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk PLoS One. 2015; 10(6):e0128106. . View in PubMed

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium Hum Mol Genet. 2014 Nov 15; 23(22):6096-111. . View in PubMed

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation Nat Commun. 2014 Sep 23; 4:4999. . View in PubMed

Family history of cancer and gastroesophageal disorders and risk of esophageal and gastric adenocarcinomas: a case-control study BMC Cancer. 2014 Feb 04; 14:60. . View in PubMed

Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):880-90. . View in PubMed

Biological effects of green tea capsule supplementation in pre-surgery postmenopausal breast cancer patients Front Oncol. 2013; 3:298. . View in PubMed

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer Nat Commun. 2013; 4:1628. . View in PubMed

Diabetes and risk of esophageal and gastric adenocarcinomas Int J Cancer. 2012 Sep 15; 131(6):1417-22. . View in PubMed

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies Lancet Oncol. 2012 Apr; 13(4):385-94. . View in PubMed

Breast epithelial cell proliferation is markedly increased with short-term high levels of endogenous estrogen secondary to controlled ovarian hyperstimulation Breast Cancer Res Treat. 2012 Apr; 132(2):653-60. . View in PubMed

Effect of 2-month controlled green tea intervention on lipoprotein cholesterol, glucose, and hormone levels in healthy postmenopausal women Cancer Prev Res (Phila). 2012 Mar; 5(3):393-402. . View in PubMed

Birth weight and other prenatal factors and risk of breast cancer in Asian-Americans Breast Cancer Res Treat. 2011 Dec; 130(3):917-25. . View in PubMed

Anthropometric, dietary, and hormonal correlates of serum adiponectin in Asian American women Nutr Cancer. 2011; 63(4):549-57. . View in PubMed

Epigenetic subgroups of esophageal and gastric adenocarcinoma with differential GATA5 DNA methylation associated with clinical and lifestyle factors PLoS One. 2011; 6(10):e25985. . View in PubMed

Dietary patterns and breast cancer risk in Asian American women Am J Clin Nutr. 2009 Apr; 89(4):1145-54. . View in PubMed

Consortium analysis of 7 candidate SNPs for ovarian cancer Int J Cancer. 2008 Jul 15; 123(2):380-388. . View in PubMed

Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations Hum Mol Genet. 2008 Mar 15; 17(6):825-34. . View in PubMed

Comprehensive evaluation of ESR2 variation and ovarian cancer risk Cancer Epidemiol Biomarkers Prev. 2008 Feb; 17(2):393-6. . View in PubMed

Epidemiology of soy exposures and breast cancer risk Br J Cancer. 2008 Jan 15; 98(1):9-14. . View in PubMed

Fiber intake and risk of adenocarcinomas of the esophagus and stomach Cancer Causes Control. 2007 Sep; 18(7):713-22. . View in PubMed

A common genetic risk factor for colorectal and prostate cancer Nat Genet. 2007 Aug; 39(8):954-6. . View in PubMed

Diabetes and risk of breast cancer in Asian-American women Carcinogenesis. 2007 Jul; 28(7):1561-6. . View in PubMed

Body size, hormone therapy and risk of breast cancer in Asian-American women Int J Cancer. 2007 Feb 15; 120(4):844-52. . View in PubMed

Estrogens, progestins, and risk of breast cancer Ernst Schering Found Symp Proc. 2007; (1):127-50. . View in PubMed

Dense breast stromal tissue shows greatly increased concentration of breast epithelium but no increase in its proliferative activity Breast Cancer Res. 2006; 8(2):R24. . View in PubMed

Associations between soy, diet, reproductive factors, and mammographic density in Singapore Chinese women Nutr Cancer. 2006; 56(2):128-35. . View in PubMed

Etiologic clues from the similarity of histology-specific trends in esophageal and lung cancers Cancer Causes Control. 2005 Nov; 16(9):1065-74. . View in PubMed

A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal women Am J Clin Nutr. 2005 May; 81(5):1133-41. . View in PubMed

Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis J Natl Cancer Inst. 2005 Jan 05; 97(1):51-9. . View in PubMed

Does mammographic density reflect ethnic differences in breast cancer incidence rates? Am J Epidemiol. 2004 Jan 15; 159(2):140-7.. View in PubMed

Adolescent and adult soy intake and risk of breast cancer in Asian-Americans Carcinogenesis. 2002 Sep; 23(9):1491-6. . View in PubMed

A multiethnic population-based study of smoking, alcohol and body size and risk of adenocarcinomas of the stomach and esophagus (United States) Cancer Causes Control. 2001 Oct; 12(8):721-32. . View in PubMed

Dietary heterocyclic amines and microsatellite instability in colon adenocarcinomas Carcinogenesis. 2001 Oct; 22(10):1681-4. . View in PubMed

A genome screen of families with multiple cases of prostate cancer: evidence of genetic heterogeneity Am J Hum Genet. 2001 Jul; 69(1):148-58. . View in PubMed

A meta-analysis of soyfoods and risk of stomach cancer: the problem of potential confounders Cancer Epidemiol Biomarkers Prev. 2000 Oct; 9(10):1051-8. . View in PubMed

Effects of soy foods on ovarian function in premenopausal women Br J Cancer. 2000 Jun; 82(11):1879-86. . View in PubMed

Diet and breast carcinoma in multiethnic populations Cancer. 2000 Mar 01; 88(5 Suppl):1239-44. . View in PubMed

Exposure misclassification bias in studies of environmental tobacco smoke and lung cancer Environ Health Perspect. 1999 Dec; 107 Suppl 6:873-7. . View in PubMed

Breast cancer and oral contraceptive use in Asian-American women Am J Epidemiol. 1999 Sep 15; 150(6):561-7. . View in PubMed

Breast Cancer among Asian Americans and Pacific Islanders Asian Am Pac Isl J Health. 1998; 6(2):327-343. . View in PubMed

Colon and Rectal Cancer among Asian Americans and Pacific Islanders Asian Am Pac Isl J Health. 1998; 6(2):184-200. . View in PubMed

Family history of cancer and risk of lung cancer among lifetime nonsmoking women in the United States Am J Epidemiol. 1996 Mar 15; 143(6):535-42. . View in PubMed

Comparison of dietary habits, physical activity and body size among Chinese in North America and China Int J Epidemiol. 1994 Oct; 23(5):984-90. . View in PubMed

Environmental tobacco smoke and lung cancer in nonsmoking womenA multicenter study. JAMA. 1994 Jun 08; 271(22):1752-9. . View in PubMed

Diet, physical activity, and colorectal cancer among Chinese in North America and China J Natl Cancer Inst. 1990 Jun 06; 82(11):915-26. . View in PubMed

Environmental tobacco smoke: exposure-response relationships in epidemiologic studies Risk Anal. 1990 Mar; 10(1):39-48. . View in PubMed

Ethnic distribution of amyloidosis: an autopsy study Mod Pathol. 1989 Jul; 2(4):372-7. . View in PubMed

Dr. Wu's research focuses on the epidemiology of cancer with emphasis on understanding the increase of various (e.g., breast, ovarian, prostate, colon ) cancers among Asian migrants to the US. A second area of research interest relates to the study of tobacco-related cancers (e.g., lung, stomach/esophagus) and genes that may be important in the metabolism of tobacco constituents.
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