CBG Faculty

Estimation of COVID-19 risk-stratified epidemiological parameters and policy implications for Los Angeles County through an integrated risk and stochastic epidemiological model medRxiv. 2020 Dec 14. . View in PubMed

Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults Environ Int. 2020 Dec; 145:106091. . View in PubMed

A Cross-Sectional Study Examining the Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies in a University Student Population J Adolesc Health. 2020 Oct 14. . View in PubMed

A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry Eur Urol. 2020 Sep; 78(3):316-320. . View in PubMed

Author Correction: Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL Sci Rep. 2020 Jan 15; 10(1):748. . View in PubMed

Correction to: Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study Cancer Causes Control. 2020 06; 31(6):607. . View in PubMed

Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk Cancer Med. 2020 05; 9(10):3563-3573. . View in PubMed

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset CancerGastroenterology. 2020 04; 158(5):1274-1286. e12. . View in PubMed

A latent unknown clustering integrating multi-omics data (LUCID) with phenotypic traits Bioinformatics. 2020 02 01; 36(3):842-850. . View in PubMed

A genome-wide association study of prostate cancer in Latinos Int J Cancer. 2020 04 01; 146(7):1819-1826. . View in PubMed

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry Blood Adv. 2020 01 14; 4(1):181-190. . View in PubMed

Association of Fish Consumption and Mercury Exposure During Pregnancy With Metabolic Health and Inflammatory Biomarkers in Children JAMA Netw Open. 2020 03 02; 3(3):e201007. . View in PubMed

Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer Hum Genet. 2019 Jul; 138(7):789-791. . View in PubMed

Correction: Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease Br J Cancer. 2019 Apr; 120(8):867. . View in PubMed

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer Hum Genet. 2019 Apr; 138(4):307-326. . View in PubMed

Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes Genet Epidemiol. 2019 10; 43(7):844-863. . View in PubMed

Alterations in folate-dependent one-carbon metabolism as colon cell transition from normal to cancerous J Nutr Biochem. 2019 07; 69:1-9. . View in PubMed

DNA methylation patterns of adult survivors of adolescent/young adult Hodgkin lymphoma compared to their unaffected monozygotic twin Leuk Lymphoma. 2019 06; 60(6):1429-1437. . View in PubMed

Epstein-Barr virus load is higher in long-term Hodgkin lymphoma survivors compared to their unaffected twins and unrelated controls Br J Haematol. 2019 04; 185(2):377-380. . View in PubMed

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos J Allergy Clin Immunol. 2019 03; 143(3):957-969. . View in PubMed

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci Nat Genet. 2019 02; 51(2):363. . View in PubMed

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study Cancer Epidemiol Biomarkers Prev. 2019 01; 28(1):208-216. . View in PubMed

Discovery of common and rare genetic risk variants for colorectal cancer Nat Genet. 2019 01; 51(1):76-87. . View in PubMed

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer JAMA Netw Open. 2019 09 04; 2(9):e1912259. . View in PubMed

Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL Sci Rep. 2019 06 28; 9(1):9371. . View in PubMed

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry Nat Commun. 2019 01 17; 10(1):382. . View in PubMed

A Unified Model for the Analysis of Gene-Environment Interaction Am J Epidemiol. 2019 04 01; 188(4):760-767. . View in PubMed

Exploratory metabolomic study to identify blood-based biomarkers as a potential screen for colorectal cancer Mol Omics. 2019 02 11; 15(1):21-29. . View in PubMed

Elucidation of causal direction between asthma and obesity: a bi-directional Mendelian randomization study Int J Epidemiol. 2019 06 01; 48(3):899-907. . View in PubMed

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci Nat Genet. 2018 07; 50(7):928-936. . View in PubMed

Genetic risk of prostate cancer in Ugandan men Prostate. 2018 04; 78(5):370-376. . View in PubMed

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants Nat Commun. 2018 06 11; 9(1):2256. . View in PubMed

Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort Front Cardiovasc Med. 2018; 5:19. . View in PubMed

Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study J Clin Oncol. 2018 05 20; 36(15):1513-1520. . View in PubMed

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium PLoS Genet. 2017 Apr; 13(4):e1006719. . View in PubMed

Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1016-1026. . View in PubMed

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation Nat Commun. 2016 Apr 07; 7:10979. . View in PubMed

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci Cancer Epidemiol Biomarkers Prev. 2016 12; 25(12):1609-1618. . View in PubMed

Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer Cancer Epidemiol. 2016 10; 44:1-4. . View in PubMed

Detecting Gene-Environment Interactions for a Quantitative Trait in a Genome-Wide Association Study Genet Epidemiol. 2016 07; 40(5):394-403. . View in PubMed

Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants PLoS One. 2016; 11(7):e0157521. . View in PubMed

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations Cancer Res. 2016 09 01; 76(17):5103-14. . View in PubMed

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci Nat Commun. 2015 Oct 26; 6:8739. . View in PubMed

Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population J Clin Oncol. 2015 Sep 10; 33(26):2901-7. . View in PubMed

Generalizability of established prostate cancer risk variants in men of African ancestry Int J Cancer. 2015 Mar 01; 136(5):1210-7. . View in PubMed

Enlight: web-based integration of GWAS results with biological annotations Bioinformatics. 2015 Jan 15; 31(2):275-6. . View in PubMed

Genetic ancestry influences asthma susceptibility and lung function among Latinos J Allergy Clin Immunol. 2015 Jan; 135(1):228-35. . View in PubMed

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD Am J Psychiatry. 2015 Jan; 172(1):82-93. . View in PubMed

Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption PLoS One. 2015; 10(7):e0126113. . View in PubMed

A novel colorectal cancer risk locus at 4q322 identified from an international genome-wide association study. Carcinogenesis. 2014 Nov; 35(11):2512-9. . View in PubMed

A comprehensive examination of breast cancer risk loci in African American women Hum Mol Genet. 2014 Oct 15; 23(20):5518-26. . View in PubMed

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer Nat Genet. 2014 Oct; 46(10):1103-9. . View in PubMed

Gender difference in interactions between MAOA promoter uVNTR polymorphism and negative familial stressors on body mass index among Chinese adolescents Pediatr Obes. 2014 Oct; 9(5):e80-90. . View in PubMed

Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai Int J Cancer. 2014 Jul 15; 135(2):335-47. . View in PubMed

A meta-analysis of Hodgkin lymphoma reveals 19p133 TCF3 as a novel susceptibility locus. Nat Commun. 2014 Jun 12; 5:3856. . View in PubMed

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age Cancer Epidemiol Biomarkers Prev. 2014 Apr; 23(4):658-69. . View in PubMed

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer Hum Mol Genet. 2013 Dec 15; 22(24):5075-82. . View in PubMed

Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer Cancer Epidemiol Biomarkers Prev. 2013 Nov; 22(11):2037-46. . View in PubMed

A scalable, knowledge-based analysis framework for genetic association studies BMC Bioinformatics. 2013 Oct 23; 14:312. . View in PubMed

Efficient two-step testing of gene-gene interactions in genome-wide association studies Genet Epidemiol. 2013 Jul; 37(5):440-51. . View in PubMed

Biomarkers for smoking cessation Clin Pharmacol Ther. 2013 Jun; 93(6):526-38. . View in PubMed

Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers--The Shanghai Bladder Cancer Study Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):937-45. . View in PubMed

Confounding and heterogeneity in genetic association studies with admixed populations Am J Epidemiol. 2013 Feb 15; 177(4):351-60. . View in PubMed

Gender-stratified gene and gene-treatment interactions in smoking cessation Pharmacogenomics J. 2012 Dec; 12(6):521-32. . View in PubMed

Analysis and optimal design for association studies using next-generation sequencing with case-control pools Genet Epidemiol. 2012 Dec; 36(8):870-81. . View in PubMed

DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers Pharmacogenet Genomics. 2012 Jul; 22(7):551-4. . View in PubMed

Cigarette smoking and subtypes of bladder cancer Int J Cancer. 2012 Feb 15; 130(4):896-901. . View in PubMed

A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p2132. Blood. 2012 Jan 12; 119(2):469-75. . View in PubMed

Genetic contribution of the leukotriene pathway to coronary artery disease Hum Genet. 2011 Jun; 129(6):617-27. . View in PubMed

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk Hum Mol Genet. 2011 Jun 01; 20(11):2263-72. . View in PubMed

Association of the calcyon neuron-specific vesicular protein gene (CALY) with adolescent smoking initiation in China and California Am J Epidemiol. 2011 May 01; 173(9):1039-48. . View in PubMed

Discovery of complex pathways from observational data Stat Med. 2010 Aug 30; 29(19):1998-2011. . View in PubMed

Genetic variation in the retinoid X receptor and calcium-sensing receptor and risk of colorectal cancer in the Colon Cancer Family Registry Carcinogenesis. 2010 Aug; 31(8):1412-6. . View in PubMed

Efficient genome-wide association testing of gene-environment interaction in case-parent trios Am J Epidemiol. 2010 Jul 01; 172(1):116-22. . View in PubMed

A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1812-21. . View in PubMed

A polytomous conditional likelihood approach for combining matched and unmatched case-control studies Stat Med. 2010 Apr 30; 29(9):1004-13. . View in PubMed

Genes involved with folate uptake and distribution and their association with colorectal cancer risk Cancer Causes Control. 2010 Apr; 21(4):597-608. . View in PubMed

Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence Cancer Res. 2010 Feb 15; 70(4):1496-504. . View in PubMed

Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry Cancer Epidemiol Biomarkers Prev. 2010 Jan; 19(1):89-100. . View in PubMed

Complex system approaches to genetic analysis Bayesian approaches Adv Genet. 2010; 72:47-71. . View in PubMed

Dopamine genes and nicotine dependence in treatment-seeking and community smokers Neuropsychopharmacology. 2009 Sep; 34(10):2252-64. . View in PubMed

Effect of tidal volume in children with acute hypoxemic respiratory failure Intensive Care Med. 2009 Aug; 35(8):1428-37. . View in PubMed

A systems biology network model for genetic association studies of nicotine addiction and treatment Pharmacogenet Genomics. 2009 Jul; 19(7):538-51. . View in PubMed

Detecting gene-environment interactions using a combined case-only and case-control approach Am J Epidemiol. 2009 Feb 15; 169(4):497-504. . View in PubMed

Comprehensive evaluation of ESR2 variation and ovarian cancer risk Cancer Epidemiol Biomarkers Prev. 2008 Feb; 17(2):393-6. . View in PubMed

DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study Cancer Epidemiol Biomarkers Prev. 2007 Nov; 16(11):2363-72. . View in PubMed

Alcohol consumption and risk of bladder cancer in Los Angeles County Int J Cancer. 2007 Aug 15; 121(4):839-45. . View in PubMed

Age-related smoking progression among adolescents in China J Adolesc Health. 2006 Nov; 39(5):686-93. . View in PubMed

A testing framework for identifying susceptibility genes in the presence of epistasis Am J Hum Genet. 2006 Jan; 78(1):15-27. . View in PubMed

Common genetic variation in the sex steroid hormone-binding globulin (SHBG) gene and circulating shbg levels among postmenopausal women: the Multiethnic Cohort J Clin Endocrinol Metab. 2005 Apr; 90(4):2198-204. . View in PubMed

A survey of current Bayesian gene mapping methods Hum Genomics. 2004 Aug; 1(5):371-4. . View in PubMed

Genetic dissection of complex traits with chromosome substitution strains of mice Science. 2004 Apr 16; 304(5669):445-8. . View in PubMed

Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2 Eur J Hum Genet. 2004 Apr; 12(4):321-32. . View in PubMed

Association of prostate cancer risk and aggressiveness to androgen pathway genes: SRD5A2, CYP17, and the AR Prostate. 2004 Apr 01; 59(1):69-76. . View in PubMed

Commentary: the concept of 'Mendelian Randomization' Int J Epidemiol. 2004 Feb; 33(1):21-5. . View in PubMed

DNA repair gene XRCC1 and XPD polymorphisms and risk of prostate cancer Cancer Epidemiol Biomarkers Prev. 2004 Jan; 13(1):23-9. . View in PubMed

Comparison of missing data approaches in linkage analysis BMC Genet. 2003 Dec 31; 4 Suppl 1:S44. . View in PubMed

CYP3A4 and CYP3A5 genotypes, haplotypes, and risk of prostate cancer Cancer Epidemiol Biomarkers Prev. 2003 Sep; 12(9):928-32. . View in PubMed

Bayesian spatial modeling of haplotype associations Hum Hered. 2003; 56(1-3):32-40. . View in PubMed

Bayesian modeling of complex metabolic pathways Hum Hered. 2003; 56(1-3):83-93. . View in PubMed