CBG Faculty
Joseph Leo Wiemels
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Adult diffuse glioma GWAS by molecular subtype identifies variants in D2HGDH and FAM20C Neuro Oncol. 2020 Nov 26; 22(11):1602-1613. . View in PubMed
Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma Acta Neuropathol Commun. 2020 Oct 28; 8(1):173. . View in PubMed
Birth Characteristics and Risk of Pediatric Thyroid Cancer: A Population-Based Record-Linkage Study in California Thyroid. 2020 Oct 07. . View in PubMed
European genetic ancestry associated with risk of childhood ependymoma Neuro Oncol. 2020 Jun 02. . View in PubMed
Birth Characteristics and Risk of Early-Onset Synovial Sarcoma Cancer Epidemiol Biomarkers Prev. 2020 Jun; 29(6):1162-1167. . View in PubMed
Common genetic variation and risk of osteosarcoma in a multi-ethnic pediatric and adolescent population Bone. 2020 01; 130:115070. . View in PubMed
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age Genome Med. 2020 03 02; 12(1):25. . View in PubMed
Germline cancer predisposition variants and pediatric glioma: a population-based study in California Neuro Oncol. 2020 06 09; 22(6):864-874. . View in PubMed
Brain tumor disparities: From biology to social determinants - The 2019 Brain Tumor Epidemiology Consortium meeting report Clin Neuropathol. 2019 Nov/Dec; 38(6):297-305. . View in PubMed
Early Infection with Cytomegalovirus and Risk of Childhood Hematologic Malignancies Cancer Epidemiol Biomarkers Prev. 2019 06; 28(6):1024-1027. . View in PubMed
Epigenomic profiling of newborns with isolated orofacial clefts reveals widespread DNA methylation changes and implicates metastable epiallele regions in disease risk Epigenetics. 2019 02; 14(2):198-213. . View in PubMed
Body mass index, comorbidities, and hormonal factors in relation to meningioma in an ethnically diverse population: the Multiethnic Cohort Neuro Oncol. 2019 03 18; 21(4):498-507. . View in PubMed
Advancing brain tumor epidemiology - multi-level integration and international collaboration: The 2018 Brain Tumor Epidemiology Consortium meeting report Clin Neuropathol. 2018 Nov/Dec; 37(6):254-261. . View in PubMed
An overview of disparities in childhood cancer: Report on the Inaugural Symposium on Childhood Cancer Health Disparities, Houston, Texas, 2016 Pediatr Hematol Oncol. 2018 Mar; 35(2):95-110. . View in PubMed
Allergies and Childhood Acute Lymphoblastic Leukemia: A Case-Control Study and Meta-analysis Cancer Epidemiol Biomarkers Prev. 2018 10; 27(10):1142-1150. . View in PubMed
A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology Haematologica. 2018 01; 103(1):e29-e31. . View in PubMed
Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium Int J Epidemiol. 2018 02 01; 47(1):22-23u. . View in PubMed
Genetic determinants of childhood and adult height associated with osteosarcoma risk Cancer. 2018 09 15; 124(18):3742-3752. . View in PubMed
BMI1 enhancer polymorphism underlies chromosome 10p1231 association with childhood acute lymphoblastic leukemia. Int J Cancer. 2018 12 01; 143(11):2647-2658. . View in PubMed
Genome-wide association analysis identifies a meningioma risk locus at 11p155. Neuro Oncol. 2018 10 09; 20(11):1485-1493. . View in PubMed
Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers Environ Health. 2018 05 02; 17(1):43. . View in PubMed
Brain tumor epidemiology in the era of precision medicine: The 2017 Brain Tumor Epidemiology Consortium meeting report Clin Neuropathol. 2017 Nov/Dec; 36(6):255-263. . View in PubMed
Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT Acta Neuropathol. 2017 06; 133(6):1001-1016. . View in PubMed
Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia Cancer Res. 2017 04 01; 77(7):1674-1683. . View in PubMed
Cesarean Section and Risk of Childhood Acute Lymphoblastic Leukemia in a Population-Based, Record-Linkage Study in California Am J Epidemiol. 2017 01 15; 185(2):96-105. . View in PubMed
Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures Environ Health. 2017 06 23; 16(1):70. . View in PubMed
Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia Oncotarget. 2016 Nov 08; 7(45):72733-72745. . View in PubMed
Childhood Leukemia: A Preventable Disease Pediatrics. 2016 Nov; 138(Suppl 1):S45-S55. . View in PubMed
Childhood Leukemia and Primary Prevention Curr Probl Pediatr Adolesc Health Care. 2016 Oct; 46(10):317-352. . View in PubMed
Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome Crit Care. 2016 May 23; 20(1):151. . View in PubMed
Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites Nucleic Acids Res. 2016 Feb 18; 44(3):1105-17. . View in PubMed
Birth weight, fetal growth, and risk of pediatric rhabdomyosarcoma: an updated record linkage study in California Ann Epidemiol. 2016 Feb; 26(2):141-145. . View in PubMed
Birth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California Eur J Cancer. 2016 12; 69:19-27. . View in PubMed
Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates Epigenetics. 2016 09; 11(9):664-673. . View in PubMed
Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia Cancer Epidemiol Biomarkers Prev. 2016 07; 25(7):1043-9. . View in PubMed
Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers Carcinogenesis. 2016 06; 37(6):576-582. . View in PubMed
A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros Leukemia. 2016 05; 30(5):1194-7. . View in PubMed
Evolving evidence on tumor and germline genetic classification of gliomas: implications for etiology and survival studies Clin Neuropathol. 2016 Jan-Feb; 35(1):31-8. . View in PubMed
A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution Cancer Res. 2015 Nov 15; 75(22):4884-94. . View in PubMed
Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children Cancer Causes Control. 2015 Apr; 26(4):609-19. . View in PubMed
Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures Nucleic Acids Res. 2015 Mar 11; 43(5):2590-602. . View in PubMed
Excess winter deaths caused by cardiovascular diseases are associated with both mild winter temperature and socio-economic inequalities in the US. Int J Cardiol. 2015; 187:642-4. . View in PubMed
Brain Tumor Epidemiology - A Hub within Multidisciplinary Neuro-oncologyReport on the 15th Brain Tumor Epidemiology Consortium (BTEC) Annual Meeting, Vienna, 2014. Clin Neuropathol. 2015 Jan-Feb; 34(1):40-6. . View in PubMed
Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia Am J Hematol. 2014 Jul; 89(7):721-5. . View in PubMed
Endogenous and exogenous hormone exposure and the risk of meningioma in men J Neurosurg. 2014 Apr; 120(4):820-6. . View in PubMed
Cancer cluster investigations: review of the past and proposals for the future Int J Environ Res Public Health. 2014 Jan 28; 11(2):1479-99. . View in PubMed
Direct and indirect targets of the E2A-PBX1 leukemia-specific fusion protein PLoS One. 2014; 9(2):e87602. . View in PubMed
Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children Leukemia. 2013 Dec; 27(12):2416-9. . View in PubMed
GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL Blood. 2013 Nov 07; 122(19):3385-7. . View in PubMed
Genetic variants in ARID5B and CEBPE are childhood ALL susceptibility loci in Hispanics Cancer Causes Control. 2013 Oct; 24(10):1789-95. . View in PubMed
Blood levels of folate at birth and risk of childhood leukemia Cancer Epidemiol Biomarkers Prev. 2013 Jun; 22(6):1088-94. . View in PubMed
Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females J Neurosurg. 2013 Mar; 118(3):649-56. . View in PubMed
Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies Genet Epidemiol. 2013 Feb; 37(2):222-8. . View in PubMed
Dental x-rays and risk of meningioma: response to DrsCalnon, Jorgensen, and White. Cancer. 2013 Jan 15; 119(2):465-6. . View in PubMed
Assessment of autoantibodies to meningioma in a population-based study Am J Epidemiol. 2013 Jan 01; 177(1):75-83. . View in PubMed
Genome-wide association study of glioma and meta-analysis Hum Genet. 2012 Dec; 131(12):1877-88. . View in PubMed
A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network Nucleic Acids Res. 2012 Dec; 40(22):11339-51. . View in PubMed
Allergy and risk of childhood acute lymphoblastic leukemia: a population-based and record-based study Am J Epidemiol. 2012 Dec 01; 176(11):970-8. . View in PubMed
Epigenetic biomarkers of T-cells in human glioma Epigenetics. 2012 Dec 01; 7(12):1391-402. . View in PubMed
A low-frequency variant at 8q2421 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat Genet. 2012 Oct; 44(10):1122-5. . View in PubMed
Dental x-rays and risk of meningioma Cancer. 2012 Sep 15; 118(18):4530-7. . View in PubMed
Fetal growth and body size genes and risk of childhood acute lymphoblastic leukemia Cancer Causes Control. 2012 Sep; 23(9):1577-85. . View in PubMed
Cigarette smoking and risk of meningioma: the effect of gender Cancer Epidemiol Biomarkers Prev. 2012 Jun; 21(6):943-50. . View in PubMed
Family and personal medical history and risk of meningioma J Neurosurg. 2011 Dec; 115(6):1072-7. . View in PubMed
Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia Cancer Causes Control. 2011 Sep; 22(9):1243-58. . View in PubMed
Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking Am J Epidemiol. 2011 Sep 01; 174(5):574-81. . View in PubMed
Early life exposure to infections and risk of childhood acute lymphoblastic leukemia Int J Cancer. 2011 Apr 01; 128(7):1632-43. . View in PubMed
DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression Neuro Oncol. 2011 Mar; 13(3):280-9. . View in PubMed
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma J Natl Cancer Inst. 2011 Jan 19; 103(2):143-53. . View in PubMed
Distinct germ line polymorphisms underlie glioma morphologic heterogeneity Cancer Genet. 2011 Jan; 204(1):13-8. . View in PubMed
Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia Blood Cells Mol Dis. 2010 Oct 15; 45(3):186-91. . View in PubMed
Circulating levels of the innate and humoral immune regulators CD14 and CD23 are associated with adult glioma Cancer Res. 2010 Oct 01; 70(19):7534-42. . View in PubMed
FLT3 mutation incidence and timing of origin in a population case series of pediatric leukemia BMC Cancer. 2010 Sep 27; 10:513. . View in PubMed
Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia Cancer Epidemiol Biomarkers Prev. 2010 Sep; 19(9):2152-63. . View in PubMed
Epidemiology and etiology of meningioma J Neurooncol. 2010 Sep; 99(3):307-14. . View in PubMed
Analysis of t(15;17) chromosomal breakpoint sequences in therapy-related versus de novo acute promyelocytic leukemia: association of DNA breaks with specific DNA motifs at PML and RARA loci Genes Chromosomes Cancer. 2010 Aug; 49(8):726-32. . View in PubMed
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake PLoS Genet. 2010 Jul 29; 6(7):e1001043. . View in PubMed
Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia Blood. 2010 Jan 14; 115(2):326-30. . View in PubMed
Copy number variation has little impact on bead-array-based measures of DNA methylation Bioinformatics. 2009 Aug 15; 25(16):1999-2005. . View in PubMed
Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles Cancer Res. 2009 Aug 01; 69(15):6315-21. . View in PubMed
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context PLoS Genet. 2009 Aug; 5(8):e1000602. . View in PubMed
4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumonia Anesthesiology. 2009 May; 110(5):1086-91. . View in PubMed
Allergies and childhood leukemia Blood Cells Mol Dis. 2009 Mar-Apr; 42(2):99-104. . View in PubMed
Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma Carcinogenesis. 2009 Mar; 30(3):416-22. . View in PubMed
Backtracking of leukemic clones to birth Methods Mol Biol. 2009; 538:7-27. . View in PubMed
Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally Cancer Res. 2008 Dec 01; 68(23):9935-44. . View in PubMed
Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium Cancer. 2008 Oct 01; 113(7 Suppl):1953-68. . View in PubMed
Chromosomal translocations in childhood leukemia: natural history, mechanisms, and epidemiology J Natl Cancer Inst Monogr. 2008; (39):87-90. . View in PubMed
Epidemiology of brain tumors Neurol Clin. 2007 Nov; 25(4):867-90vii. . View in PubMed
DNA quantification of whole genome amplified samples for genotyping on a multiplexed bead array platform Cancer Epidemiol Biomarkers Prev. 2007 Aug; 16(8):1686-90. . View in PubMed
Exogenous hormone use and meningioma risk: what do we tell our patients? Cancer. 2007 Aug 01; 110(3):471-6.. View in PubMed
Allergy-related polymorphisms influence glioma status and serum IgE levels Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1229-35. . View in PubMed
Accuracy of multiplexed Illumina platform-based single-nucleotide polymorphism genotyping compared between genomic and whole genome amplified DNA collected from multiple sources Cancer Epidemiol Biomarkers Prev. 2006 Dec; 15(12):2533-6. . View in PubMed
Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways Intensive Care Med. 2006 Sep; 32(9):1293-303. . View in PubMed
Cytogenetics of Hispanic and White children with acute lymphoblastic leukemia in California Cancer Epidemiol Biomarkers Prev. 2006 Mar; 15(3):578-81. . View in PubMed
Epidemiology of intracranial meningioma Neurosurgery. 2005 Dec; 57(6):1088-95; discussion 1088-95. . View in PubMed
ERCC1 and ERCC2 polymorphisms and adult glioma Neuro Oncol. 2005 Oct; 7(4):495-507. . View in PubMed
Ethnic difference in daycare attendance, early infections, and risk of childhood acute lymphoblastic leukemia Cancer Epidemiol Biomarkers Prev. 2005 Aug; 14(8):1928-34. . View in PubMed
DNA topoisomerase II in therapy-related acute promyelocytic leukemia N Engl J Med. 2005 Apr 14; 352(15):1529-38. . View in PubMed
Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia Genes Chromosomes Cancer. 2003 Feb; 36(2):175-88. . View in PubMed