Michael Frederick Press, MD, PhD

Michael F. Press, M.D., Ph.D. is a professor in the Department of Pathology and co-leader of the Women’s Cancers Program. He received his M.D., Ph.D. and residency training at the University of Chicago. He was a member of the University of Chicago faculty for seven years before joining the faculty of the University of Southern California in 1988. Dr. Press is currently the director for the Breast Cancer International Research Group Central Laboratory, the coordinator of the Breast Cancer Program at USC Norris Cancer Center and holds the Harold E. Lee Chair in Cancer Research in the USC Norris Cancer Center. His research interests are molecular genetic alterations in breast and gynecologic cancers.

• Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia Hum Mol Genet. 2024 Jan 23. . View in PubMed
• RANK and RANKL Expression in Tumors of Patients with Early Breast Cancer Geburtshilfe Frauenheilkd. 2024 Jan; 84(1):77-85. . View in PubMed
• Discordance of HER2 Expression and/or Amplification on Repeat Testing Mol Cancer Ther. 2023 Aug 01; 22(8):976-984. . View in PubMed
• ESMO expert consensus statements (ECS) on the definition, diagnosis, and management of HER2-low breast cancer Ann Oncol. 2023 08; 34(8):645-659. . View in PubMed
• Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer J Clin Oncol. 2023 03 20; 41(9):1638-1645. . View in PubMed
• Breast Cancer Res. 2023 01 11; 25(1):2. . View in PubMed
• Preclinical Efficacy of the Antibody-Drug Conjugate CLDN6-23-ADC for the Treatment of CLDN6-Positive Solid Tumors Clin Cancer Res. 2023 06 01; 29(11):2131-2143. . View in PubMed
• A Multi-Center Clinical Study to Harvest and Characterize Circulating Tumor Cells from Patients with Metastatic Breast Cancer Using the Parsortix® PC1 System Cancers (Basel). 2022 Oct 26; 14(21). . View in PubMed
• Lifetime personal cigarette smoking and risk of young-onset breast cancer by subtype among non-Hispanic Black and White women in the Young Women’s Health History Study Breast Cancer Res Treat. 2022 Oct; 195(3):353-366. . View in PubMed
• Molecular Assessment of HER2 to Identify Signatures Associated with Therapy Response in HER2-Positive Breast Cancer Cancers (Basel). 2022 Jun 04; 14(11). . View in PubMed
• Circulating Tumor Cell Transcriptomics as Biopsy Surrogates in Metastatic Breast Cancer Ann Surg Oncol. 2022 May; 29(5):2882-2894. . View in PubMed
• Correction to: Circulating Tumor Cell Transcriptomics as Biopsy Surrogates in Metastatic Breast Cancer Ann Surg Oncol. 2022 May; 29(5):3064. . View in PubMed
• A Systematic Review and Meta-Analysis of Smoking and Circulating Sex Hormone Levels Among Premenopausal Women Nicotine Tob Res. 2022 10 26; 24(11):1705-1713. . View in PubMed
• A Standardized Investigational Ki-67 Immunohistochemistry Assay Used to Assess High-Risk Early Breast Cancer Patients in the monarchE Phase 3 Clinical Study Identifies a Population With Greater Risk of Disease Recurrence When Treated With Endocrine Therapy Alone Appl Immunohistochem Mol Morphol. 2022 04 01; 30(4):237-245. . View in PubMed
• Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach Hum Mol Genet. 2022 09 10; 31(18):3133-3143. . View in PubMed
• A careful reassessment of anthracycline use in curable breast cancer NPJ Breast Cancer. 2021 Oct 08; 7(1):134. . View in PubMed
• Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response Nat Cancer. 2021 04; 2(4):400-413. . View in PubMed
• Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women Nat Commun. 2021 07 07; 12(1):4198. . View in PubMed
• Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry Am J Hum Genet. 2021 04 01; 108(4):564-582. . View in PubMed
• Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic Breast Cancer: Updated Results of ALTERNATIVE J Clin Oncol. 2021 01 01; 39(1):79-89. . View in PubMed
• Clinical evaluation of BCL-2/XL levels pre- and post- HER2-targeted therapy PLoS One. 2021; 16(5):e0251163. . View in PubMed
• Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry J Natl Cancer Inst. 2021 09 04; 113(9):1168-1176. . View in PubMed
• Impact of fibroblast growth factor receptor 1 (FGFR1) amplification on the prognosis of breast cancer patients Breast Cancer Res Treat. 2020 Nov; 184(2):311-324. . View in PubMed
• Testing considerations for phosphatidylinositol-3-kinase catalytic subunit alpha as an emerging biomarker in advanced breast cancer Cancer Med. 2020 09; 9(18):6463-6472. . View in PubMed
• Case-Based Review and Clinical Guidance on the Use of Genomic Assays for Early-Stage Breast Cancer: Breast Cancer Therapy Expert Group (BCTEG) Clin Breast Cancer. 2020 06; 20(3):183-193. . View in PubMed
• A Roundtable Discussion of the Breast Cancer Therapy Expert Group (BCTEG): Clinical Developments and Practice Guidance on Human Epidermal Growth Factor Receptor 2 (HER2)-positive Breast Cancer Clin Breast Cancer. 2020 06; 20(3):e251-e260. . View in PubMed
• Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers Cancer Discov. 2020 01; 10(1):86-103. . View in PubMed
• Deep learning-enabled breast cancer hormonal receptor status determination from base-level H&E stains Nat Commun. 2020 11 16; 11(1):5727. . View in PubMed
• Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07) Nat Commun. 2020 11 17; 11(1):5824. . View in PubMed
• Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2- Breast Cancer Clin Cancer Res. 2020 02 01; 26(3):566-580. . View in PubMed
• A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry Blood Adv. 2020 01 14; 4(1):181-190. . View in PubMed
• Publisher Correction: Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy Nat Commun. 2019 May 30; 10(1):2433. . View in PubMed
• Role for polo-like kinase 4 in mediation of cytokinesis Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11309-11318. . View in PubMed
• Assessment of ERBB2/HER2 Status in HER2-Equivocal Breast Cancers by FISH and 2013/2014 ASCO-CAP Guidelines JAMA Oncol. 2019 03 01; 5(3):366-375. . View in PubMed
• Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy Nat Commun. 2019 02 08; 10(1):657. . View in PubMed
• Comparison of central laboratory assessments of ER, PR, HER2, and Ki67 by IHC/FISH and the corresponding mRNAs (ESR1, PGR, ERBB2, and MKi67) by RT-qPCR on an automated, broadly deployed diagnostic platform Breast Cancer Res Treat. 2018 Nov; 172(2):327-338. . View in PubMed
• RNA-Seq of Circulating Tumor Cells in Stage II-III Breast Cancer Ann Surg Oncol. 2018 Aug; 25(8):2261-2270. . View in PubMed
• Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update Arch Pathol Lab Med. 2018 11; 142(11):1364-1382. . View in PubMed
• Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer Lung Cancer. 2018 09; 123:91-98. . View in PubMed
• Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic Breast Cancer: ALTERNATIVE J Clin Oncol. 2018 03 10; 36(8):741-748. . View in PubMed
• Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines Cell Rep. 2018 11 27; 25(9):2617-2633. . View in PubMed
• Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update J Clin Oncol. 2018 07 10; 36(20):2105-2122. . View in PubMed
• Body mass index at age 18 years and recent body mass index in relation to risk of breast cancer overall and ER/PR/HER2-defined subtypes in white women and African-American women: a pooled analysis Breast Cancer Res. 2018 01 22; 20(1):5. . View in PubMed
• Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium PLoS Genet. 2017 Apr; 13(4):e1006719. . View in PubMed
• Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1016-1026. . View in PubMed
• HER2 Status in Advanced or Metastatic Gastric, Esophageal, or Gastroesophageal Adenocarcinoma for Entry to the TRIO-013/LOGiC Trial of Lapatinib Mol Cancer Ther. 2017 01; 16(1):228-238. . View in PubMed
• Reproductive factors and the risk of triple-negative breast cancer in white women and African-American women: a pooled analysis Breast Cancer Res. 2017 01 13; 19(1):6. . View in PubMed
• Human-derived normal mesenchymal stem/stromal cells in anticancer therapies J Cancer. 2017; 8(1):85-96. . View in PubMed
• A functionally significant SNP in TP53 and breast cancer risk in African-American women NPJ Breast Cancer. 2017; 3:5. . View in PubMed
• Prognostic Value of Intrinsic Subtypes in Hormone Receptor-Positive Metastatic Breast Cancer Treated With Letrozole With or Without Lapatinib JAMA Oncol. 2016 Oct 01; 2(10):1287-1294. . View in PubMed
• Serum Human Epidermal Growth Factor 2 Extracellular Domain as a Predictive Biomarker for Lapatinib Treatment Efficacy in Patients With Advanced Breast Cancer J Clin Oncol. 2016 Mar 20; 34(9):936-44. . View in PubMed
• Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2-overexpressing cancer cells Oncotarget. 2016 Feb 23; 7(8):9561-75. . View in PubMed
• Lapatinib in Combination With Capecitabine Plus Oxaliplatin in Human Epidermal Growth Factor Receptor 2-Positive Advanced or Metastatic Gastric, Esophageal, or Gastroesophageal Adenocarcinoma: TRIO-013/LOGiC–A Randomized Phase III Trial J Clin Oncol. 2016 Feb 10; 34(5):443-51. . View in PubMed
• A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci Cancer Epidemiol Biomarkers Prev. 2016 12; 25(12):1609-1618. . View in PubMed
• Assessing the New American Society of Clinical Oncology/College of American Pathologists Guidelines for HER2 Testing by Fluorescence In Situ Hybridization: Experience of an Academic Consultation Practice Arch Pathol Lab Med. 2016 11; 140(11):1250-1258. . View in PubMed
• Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry Hum Genet. 2016 10; 135(10):1145-59. . View in PubMed
• Long-term outcomes after adjuvant treatment of sequential versus combination docetaxel with doxorubicin and cyclophosphamide in node-positive breast cancer: BCIRG-005 randomized trial Ann Oncol. 2016 06; 27(6):1041-1047. . View in PubMed
• Genome-wide association studies in women of African ancestry identified 3q2621 as a novel susceptibility locus for oestrogen receptor negative breast cancer. Hum Mol Genet. 2016 11 01; 25(21):4835-4846. . View in PubMed
• HER2 Gene Amplification Testing by Fluorescent In Situ Hybridization (FISH): Comparison of the ASCO-College of American Pathologists Guidelines With FISH Scores Used for Enrollment in Breast Cancer International Research Group Clinical Trials J Clin Oncol. 2016 10 10; 34(29):3518-3528. . View in PubMed
• Many private mutations originate from the first few divisions of a human colorectal adenoma J Pathol. 2015 Nov; 237(3):355-62. . View in PubMed
• Mutations in the Kinase Domain of the HER2/ERBB2 Gene Identified in a Wide Variety of Human Cancers J Mol Diagn. 2015 Sep; 17(5):487-95. . View in PubMed
• Reduced risk of breast cancer associated with recreational physical activity varies by HER2 status Cancer Med. 2015 Jul; 4(7):1122-35. . View in PubMed
• Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness Sci Rep. 2015 Jun 08; 5:11207. . View in PubMed
• PTEN Loss Is Associated with Worse Outcome in HER2-Amplified Breast Cancer Patients but Is Not Associated with Trastuzumab Resistance Clin Cancer Res. 2015 May 01; 21(9):2065-74. . View in PubMed
• Reply to EA. Rakha et al. J Clin Oncol. 2015 Apr 10; 33(11):1302-4. . View in PubMed
• A Big Bang model of human colorectal tumor growth Nat Genet. 2015 Mar; 47(3):209-16. . View in PubMed
• Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults PLoS One. 2015; 10(6):e0131106. . View in PubMed
• Molecular markers for breast cancer diagnosis, prognosis and targeted therapy J Surg Oncol. 2015 Jan; 111(1):81-90. . View in PubMed
• Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia Clin Epigenetics. 2015; 7:117. . View in PubMed
• A comprehensive examination of breast cancer risk loci in African American women Hum Mol Genet. 2014 Oct 15; 23(20):5518-26. . View in PubMed
• Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture Am J Hum Genet. 2014 Oct 02; 95(4):437-44. . View in PubMed
• Meta-analysis of loci associated with age at natural menopause in African-American women Hum Mol Genet. 2014 Jun 15; 23(12):3327-42. . View in PubMed
• HER2 and TOP2A amplification in a hospital-based cohort of breast cancer patients: associations with patient and tumor characteristics Breast Cancer Res Treat. 2014 May; 145(1):193-203. . View in PubMed
• Quantitative ER and PgR assessment as predictors of benefit from lapatinib in postmenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer Clin Cancer Res. 2014 Feb 01; 20(3):736-43. . View in PubMed
• Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update Arch Pathol Lab Med. 2014 Feb; 138(2):241-56. . View in PubMed
• Characterization of HER2 status by fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) Methods Mol Biol. 2014; 1180:181-207. . View in PubMed
• A conceptual and methodological framework for investigating etiologic heterogeneity Stat Med. 2013 Dec 20; 32(29):5039-52. . View in PubMed
• Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update J Clin Oncol. 2013 Nov 01; 31(31):3997-4013. . View in PubMed
• Genome-wide association study of age at menarche in African-American women Hum Mol Genet. 2013 Aug 15; 22(16):3329-46. . View in PubMed
• Assessment of HER2 gene amplification in adenocarcinomas of the stomach or gastroesophageal junction in the INT-0116/SWOG9008 clinical trial Ann Oncol. 2013 Jul; 24(7):1754-1761. . View in PubMed
• A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry Nat Genet. 2013 Jun; 45(6):690-6. . View in PubMed
• Mortality risk of black women and white women with invasive breast cancer by hormone receptors, HER2, and p53 status BMC Cancer. 2013 May 04; 13:225. . View in PubMed
• Genome-wide association studies identify four ER negative-specific breast cancer risk loci Nat Genet. 2013 Apr; 45(4):392-8398e1-2. . View in PubMed
• Immunohistochemistry and fluorescence in situ hybridization assessment of HER2 in clinical trials of adjuvant therapy for breast cancer (NCCTG N9831, BCIRG 006, and BCIRG 005) Breast Cancer Res Treat. 2013 Feb; 138(1):99-108. . View in PubMed
• Quantitative measures of estrogen receptor expression in relation to breast cancer-specific mortality risk among white women and black women Breast Cancer Res. 2013; 15(5):R90. . View in PubMed
• A genome-wide association study of breast cancer in women of African ancestry Hum Genet. 2013 Jan; 132(1):39-48. . View in PubMed
• A genome-wide scan for breast cancer risk haplotypes among African American women PLoS One. 2013; 8(2):e57298. . View in PubMed
• A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11 Hum Mol Genet. 2012 Dec 15; 21(24):5373-84. . View in PubMed
• Overexpression of SERBP1 (Plasminogen activator inhibitor 1 RNA binding protein) in human breast cancer is correlated with favourable prognosis BMC Cancer. 2012 Dec 13; 12:597. . View in PubMed
• Impact of breast cancer subtypes and treatment on survival: an analysis spanning two decades Cancer Epidemiol Biomarkers Prev. 2012 Oct; 21(10):1848-55. . View in PubMed
• Lowering oral contraceptive norethindrone dose increases estrogen and progesterone receptor levels with no reduction in proliferation of breast epithelium: a randomized trial Contraception. 2012 Sep; 86(3):238-43. . View in PubMed
• Endometrial cancer survival after breast cancer in relation to tamoxifen treatment: pooled results from three countries Breast Cancer Res. 2012 Jun 12; 14(3):R91. . View in PubMed
• Potential utility of an expression array signature for predicting anthracycline responsiveness or resistance J Clin Oncol. 2012 Feb 01; 30(4):357-61. . View in PubMed
• Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans Hum Mol Genet. 2011 Nov 15; 20(22):4491-503. . View in PubMed
• Risk factors by molecular subtypes of breast cancer across a population-based study of women 56 years or younger Breast Cancer Res Treat. 2011 Nov; 130(2):587-97. . View in PubMed
• Pathological characteristics of BRCA-associated breast cancers in Hispanics Breast Cancer Res Treat. 2011 Nov; 130(1):281-9. . View in PubMed
• A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer Nat Genet. 2011 Oct 30; 43(12):1210-4. . View in PubMed
• Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry PLoS Genet. 2011 Oct; 7(10):e1002298. . View in PubMed
• Obesity and survival among black women and white women 35 to 64 years of age at diagnosis with invasive breast cancer J Clin Oncol. 2011 Sep 01; 29(25):3358-65. . View in PubMed
• The landscape of recombination in African Americans Nature. 2011 Jul 20; 476(7359):170-5. . View in PubMed
• Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium PLoS Genet. 2011 Apr; 7(4):e1001371. . View in PubMed
• Alteration of topoisomerase II-alpha gene in human breast cancer: association with responsiveness to anthracycline-based chemotherapy J Clin Oncol. 2011 Mar 01; 29(7):859-67. . View in PubMed
• Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): two highly active therapeutic regimens J Clin Oncol. 2011 Jan 10; 29(2):149-56. . View in PubMed
• Genome-scale screen for DNA methylation-based detection markers for ovarian cancer PLoS One. 2011; 6(12):e28141. . View in PubMed
• Fine scale mapping of the breast cancer 16q12 locus Hum Mol Genet. 2010 Jun 15; 19(12):2507-15. . View in PubMed
• A case-control study of body mass index and breast cancer risk in white and African-American women Cancer Epidemiol Biomarkers Prev. 2010 Jun; 19(6):1532-44. . View in PubMed
• Chromosome 17 polysomy without human epidermal growth factor receptor 2 amplification does not predict response to lapatinib plus paclitaxel compared with paclitaxel in metastatic breast cancer Clin Cancer Res. 2010 Feb 15; 16(4):1281-8. . View in PubMed
• Use of four biomarkers to evaluate the risk of breast cancer subtypes in the women’s contraceptive and reproductive experiences study Cancer Res. 2010 Jan 15; 70(2):575-87. . View in PubMed
• Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer J Clin Oncol. 2009 Nov 20; 27(33):5538-46. . View in PubMed
• Prognostic and predictive value of HER2 extracellular domain in metastatic breast cancer treated with lapatinib and paclitaxel in a randomized phase III study J Clin Oncol. 2009 Nov 20; 27(33):5552-8. . View in PubMed
• An admixture scan in 1,484 African American women with breast cancer Cancer Epidemiol Biomarkers Prev. 2009 Nov; 18(11):3110-7. . View in PubMed
• Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 (HER2), and epidermal growth factor receptor expression and benefit from lapatinib in a randomized trial of paclitaxel with lapatinib or placebo as first-line treatment in HER2-negative or unknown metastatic breast cancer J Clin Oncol. 2009 Aug 20; 27(24):3908-15. . View in PubMed
• Breast cancer receptor status: do results from a centralized pathology laboratory agree with SEER registry reports? Cancer Epidemiol Biomarkers Prev. 2009 Aug; 18(8):2214-20.. View in PubMed
• Relationship between migraine history and breast cancer risk among premenopausal and postmenopausal women Cancer Epidemiol Biomarkers Prev. 2009 Jul; 18(7):2030-4. . View in PubMed
• Alterations in the TOP2A and HER2 genes: association with adjuvant anthracycline sensitivity in human breast cancers J Natl Cancer Inst. 2009 May 06; 101(9):615-8. . View in PubMed
• Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X PLoS Genet. 2009 May; 5(5):e1000490. . View in PubMed
• FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation Hum Mol Genet. 2009 May 01; 18(9):1692-703. . View in PubMed
• Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologic considerations J Clin Oncol. 2009 Mar 10; 27(8):1323-33. . View in PubMed
• A phase I/II trial of trastuzumab plus erlotinib in metastatic HER2-positive breast cancer: a dual ErbB targeted approach Clin Breast Cancer. 2009 Feb; 9(1):16-22. . View in PubMed
• Cancer Epidemiol Biomarkers Prev. 2009 Feb; 18(2):479-85. . View in PubMed
• Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort BMC Cancer. 2009 Jan 30; 9:43. . View in PubMed
• HER2 gene amplification and EGFR expression in a large cohort of surgically staged patients with nonendometrioid (type II) endometrial cancer Br J Cancer. 2009 Jan 13; 100(1):89-95. . View in PubMed
• HER-2 gene amplification, HER-2 and epidermal growth factor receptor mRNA and protein expression, and lapatinib efficacy in women with metastatic breast cancer Clin Cancer Res. 2008 Dec 01; 14(23):7861-70. . View in PubMed
• Phase III, double-blind, randomized study comparing lapatinib plus paclitaxel with placebo plus paclitaxel as first-line treatment for metastatic breast cancer J Clin Oncol. 2008 Dec 01; 26(34):5544-52. . View in PubMed
• Breast cancer risk and hormone receptor status in older women by parity, age of first birth, and breastfeeding: a case-control study Cancer Epidemiol Biomarkers Prev. 2008 Jul; 17(7):1723-30. . View in PubMed
• Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American women Cancer Genet Cytogenet. 2008 Feb; 181(1):16-9. . View in PubMed
• Timing of menarche and first full-term birth in relation to breast cancer risk Am J Epidemiol. 2008 Jan 15; 167(2):230-9. . View in PubMed
• The ubiquitin-like molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer Breast Cancer Res. 2008; 10(4):R58. . View in PubMed
• A variant in the cytochrome p450 oxidoreductase gene is associated with breast cancer risk in African Americans Cancer Res. 2007 Apr 15; 67(8):3565-8. . View in PubMed
• Serum organochlorines and breast cancer: a case-control study among African-American women Cancer Causes Control. 2007 Feb; 18(1):29-39. . View in PubMed
• American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer J Clin Oncol. 2007 Jan 01; 25(1):118-45. . View in PubMed
• American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer Arch Pathol Lab Med. 2007; 131(1):18-43. . View in PubMed
• EGFR, HER2 and VEGF pathways: validated targets for cancer treatment Drugs. 2007; 67(14):2045-75. . View in PubMed
• Oral contraceptive use and risk of breast carcinoma in situ (United States) Cancer Causes Control. 2006 Nov; 17(9):1155-62. . View in PubMed
• How is Her-2/neu status established when Her-2/neu and chromosome 17 centromere are both amplified? Am J Clin Pathol. 2006 Nov; 126(5):673-4.. View in PubMed
• Receptor tyrosine kinase EphB4 is a survival factor in breast cancer Am J Pathol. 2006 Jul; 169(1):279-93. . View in PubMed
• HER2 testing in breast cancer: NCCN Task Force report and recommendations J Natl Compr Canc Netw. 2006 Jul; 4 Suppl 3:S1-22; quiz S23-4. . View in PubMed
• Breast cancer risk estimates for relatives of white and African American women with breast cancer in the Women’s Contraceptive and Reproductive Experiences Study J Clin Oncol. 2006 Jun 01; 24(16):2498-504. . View in PubMed
• Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancer Cancer Epidemiol Biomarkers Prev. 2006 May; 15(5):946-54. . View in PubMed
• Lifetime recreational exercise activity and breast cancer risk among black women and white women J Natl Cancer Inst. 2005 Nov 16; 97(22):1671-9. . View in PubMed
• Diagnostic evaluation of HER-2 as a molecular target: an assessment of accuracy and reproducibility of laboratory testing in large, prospective, randomized clinical trials Clin Cancer Res. 2005 Sep 15; 11(18):6598-607. . View in PubMed
• Association of p53 mutations and a codon 72 single nucleotide polymorphism with lower overall survival and responsiveness to adjuvant radiotherapy in endometrioid endometrial carcinomas Int J Gynecol Cancer. 2005 Sep-Oct; 15(5):952-63. . View in PubMed
• Determination of HER2 gene amplification by fluorescence in situ hybridization and concordance with the clinical trials immunohistochemical assay in women with metastatic breast cancer evaluated for treatment with trastuzumab Breast Cancer Res Treat. 2005 Sep; 93(1):3-11. . View in PubMed
• Reproductive factors and subtypes of breast cancer defined by hormone receptor and histology Br J Cancer. 2005 Aug 08; 93(3):364-71. . View in PubMed
• Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with trastuzumab Clin Breast Cancer. 2005 Aug; 6(3):240-6. . View in PubMed
• Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging Cancer Res. 2005 Jul 01; 65(13):5907-16. . View in PubMed
• Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer J Clin Oncol. 2005 Apr 10; 23(11):2534-43. . View in PubMed
• Consensus statement: Expedition Inspiration 2004 Breast Cancer Symposium ‘Breast Cancer–The Development and Validation of New Therapeutics’ Breast Cancer Res Treat. 2005 Mar; 90(1):1-3. . View in PubMed
• Racial differences in the familial aggregation of breast cancer and other female cancers Breast Cancer Res Treat. 2005 Feb; 89(3):227-35. . View in PubMed
• Impact of reproductive factors and lactation on breast carcinoma in situ risk Int J Cancer. 2004 May 20; 110(1):102-9. . View in PubMed
• Results of two open-label, multicenter phase II studies of docetaxel, platinum salts, and trastuzumab in HER2-positive advanced breast cancer J Natl Cancer Inst. 2004 May 19; 96(10):759-69. . View in PubMed
• Characterization of engineered anti-p185HER-2 (scFv-CH3)2 antibody fragments (minibodies) for tumor targeting Protein Eng Des Sel. 2004 Apr; 17(4):315-23. . View in PubMed
• Identification of TP53 mutations in human cancers using oligonucleotide microarrays Methods Mol Med. 2004; 97:323-35. . View in PubMed
• Lifetime recreational exercise activity and risk of breast carcinoma in situ Cancer. 2003 Nov 15; 98(10):2161-9. . View in PubMed
• Antibody-mediated targeting of replication-competent retroviral vectors Hum Gene Ther. 2003 May 20; 14(8):789-802. . View in PubMed
• P7 antigen expression in human breast cancer Clin Cancer Res. 2003 Jan; 9(1):201-6. . View in PubMed
• Comparison of different antibodies for detection of progesterone receptor in breast cancer Steroids. 2002 Aug; 67(9):799-813. . View in PubMed
• Evaluation of HER-2/neu gene amplification and overexpression: comparison of frequently used assay methods in a molecularly characterized cohort of breast cancer specimens J Clin Oncol. 2002 Jul 15; 20(14):3095-105. . View in PubMed
• The NICHD Women’s Contraceptive and Reproductive Experiences Study: methods and operational results Ann Epidemiol. 2002 May; 12(4):213-21. . View in PubMed
• Germ-line HER-2 variant and breast cancer risk by stage of disease Cancer Res. 2001 Dec 01; 61(23):8393-4. . View in PubMed
• Alternative and aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer Cancer Res. 2001 Apr 01; 61(7):3212-9. . View in PubMed
• Breast cancer susceptibility gene 1 (BRCAI) is a coactivator of the androgen receptor Cancer Res. 2000 Nov 01; 60(21):5946-9. . View in PubMed
• Comparison of TP53 mutations identified by oligonucleotide microarray and conventional DNA sequence analysis Cancer Res. 2000 May 15; 60(10):2716-22. . View in PubMed
• p21 (WAF1/CIP1) protein expression is associated with prolonged survival but not with p53 expression in epithelial ovarian carcinoma Gynecol Oncol. 2000 May; 77(2):237-42. . View in PubMed
• Reduction of BRCA1 expression in sporadic ovarian cancer Gynecol Oncol. 2000 Mar; 76(3):294-300. . View in PubMed
• p53 mutations and expression in breast carcinoma in situ Am J Pathol. 2000 Jan; 156(1):183-91. . View in PubMed
• Assessment of novel anti-p185HER-2 monoclonal antibodies for internalization-dependent therapies Hybridoma. 1999 Dec; 18(6):487-95. . View in PubMed
• The risk of angiosarcoma following primary breast cancer Br J Cancer. 1999 Oct; 81(3):532-6. . View in PubMed
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• Lenz, Heinz-Josef
• Haiman, Christopher
• Matsuo, Koji
• Ulaner, Gary
• Wu-Williams, Anna