Faculty

Laura Perin Gallandt, PhD
Laura Perin Gallandt, PhD
Assistant Professor of Research Urology
Pediatrics
CHL MailStop 35 Off Campus Los Angeles
Laura Perin, MD, is an Assistant Professor at Keck School of Medicine, University of Southern California. Before joining the faculty at USC she was a research fellow at Harvard School of Medicine, where she obtained her PhD, and a postdoctoral fellow at Children Hospital of Los Angeles. She is a recipient of many intramural and extramural awards including CIRM, American Urology Foundation, Alport Foundation, etc. Her research focuses on the application of human and mouse amniotic fluid
stem cells (AFSC) in animal models of acute and chronic kidney, pancreas and lung. In addition, Dr. Perin is investigating the mechanism of action of stem cells and how AFSC provide organ protection thorough their modulatory effects.

T-cell exhaustion correlates with improved outcomes in kidney transplant recipients Kidney Int. 2019 Feb 27. . View in PubMed

Concise Reviews: Stem Cells and Kidney Regeneration: An Update Stem Cells Transl Med. 2019 Jan; 8(1):82-92. . View in PubMed

Concise Reviews: Stem Cells and Kidney Regeneration: An Update Stem Cells Transl Med. 2018 Oct 09. . View in PubMed

Amniotic fluid cells: current progress and emerging challenges in renal regeneration Pediatr Nephrol. 2018 Jun; 33(6):935-945. . View in PubMed

Impact of preformed T-cell alloreactivity by means of donor-specific and panel of reactive T cells (PRT) ELISPOT in kidney transplantation PLoS One. 2018; 13(7):e0200696. . View in PubMed

Amniotic fluid stem cell-derived vesicles protect from VEGF-induced endothelial damage Sci Rep. 2017 Dec 04; 7(1):16875. . View in PubMed

Regenerative immunology: the immunological reaction to biomaterials Transpl Int. 2017 Dec; 30(12):1199-1208. . View in PubMed

Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging Thyroid. 2017 Oct; 27(10):1316-1322. . View in PubMed

Amniotic fluid cells: current progress and emerging challenges in renal regeneration Pediatr Nephrol. 2017 Jun 15. . View in PubMed

Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome Nephrol Dial Transplant. 2017 Jun 01; 32(6):916-924. . View in PubMed

Fasting-Mimicking Diet Promotes Ngn3-Driven ß-Cell Regeneration to Reverse DiabetesCell. 2017 Feb 23; 168(5):775-788. e12. . View in PubMed

Direct Isolation and Characterization of Human Nephron Progenitors Stem Cells Transl Med. 2017 Feb; 6(2):419-433. . View in PubMed

Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging Thyroid. 2017 10; 27(10):1316-1322. . View in PubMed

A step towards clinical application of acellular matrix: A clue from macrophage polarization Matrix Biol. 2017 01; 57-58:334-346. . View in PubMed

Fasting-Mimicking Diet Promotes Ngn3-Driven ß-Cell Regeneration to Reverse DiabetesCell. 2017 02 23; 168(5):775-788. e12. . View in PubMed

Extracellular matrix scaffolds as a platform for kidney regeneration Eur J Pharmacol. 2016 Nov 05; 790:21-27. . View in PubMed

Decellularized Renal Matrix and Regenerative Medicine of the Kidney: A Different Point of View Tissue Eng Part B Rev. 2016 06; 22(3):183-92. . View in PubMed

Thyroid Hormone Receptor a Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury Endocrinology. 2016 Jan; 157(1):4-15. . View in PubMed

Tissue-Engineering Approaches to Restore Kidney Function Curr Diab Rep. 2015 Oct; 15(10):69. . View in PubMed

Renal Extracellular Matrix Scaffolds From Discarded Kidneys Maintain Glomerular Morphometry and Vascular Resilience and Retains Critical Growth Factors Transplantation. 2015 Sep; 99(9):1807-16. . View in PubMed

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan Cell Metab. 2015 Jul 07; 22(1):86-99. . View in PubMed

Alport syndrome from bench to bedside: the potential of current treatment beyond RAAS blockade and the horizon of future therapies Nephrol Dial Transplant. 2014 Sep; 29 Suppl 4:iv124-30. . View in PubMed

Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression Cell Stem Cell. 2014 Jun 05; 14(6):810-23. . View in PubMed

Amniotic fluid stem cells prevent ß-cell injury Cytotherapy. 2014 Jan; 16(1):41-55. . View in PubMed

Amniotic fluid stem cells inhibit the progression of bleomycin-induced pulmonary fibrosis via CCL2 modulation in bronchoalveolar lavage PLoS One. 2013; 8(8):e71679. . View in PubMed

A novel source of cultured podocytes PLoS One. 2013; 8(12):e81812. . View in PubMed

Injection of amniotic fluid stem cells delays progression of renal fibrosis J Am Soc Nephrol. 2012 Apr; 23(4):661-73. . View in PubMed

Stem cells as a therapeutic approach to chronic kidney diseases Curr Urol Rep. 2012 Feb; 13(1):47-54. . View in PubMed

ß-Cell regeneration mediated by human bone marrow mesenchymal stem cells PLoS One. 2012; 7(8):e42177. . View in PubMed

The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors Am J Respir Cell Mol Biol. 2011 Dec; 45(6):1212-21. . View in PubMed

Differentiation of nestin-positive cells derived from bone marrow into pancreatic endocrine and ductal cells in vitro J Endocrinol. 2011 May; 209(2):193-201. . View in PubMed

Regenerative medicine of the kidney Adv Drug Deliv Rev. 2011 Apr 30; 63(4-5):379-87. . View in PubMed

Amniotic fluid as a source of pluripotent and multipotent stem cells for organ regeneration Curr Opin Organ Transplant. 2011 Feb; 16(1):101-5. . View in PubMed

Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications J Urol. 2010 Mar; 183(3):1193-200. . View in PubMed

Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis PLoS One. 2010 Feb 24; 5(2):e9357. . View in PubMed

Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages Stem Cells. 2008 Nov; 26(11):2902-11. . View in PubMed

Stem/progenitor cells in lung development, injury repair, and regeneration Proc Am Thorac Soc. 2008 Aug 15; 5(6):703-6. . View in PubMed

Current status of tissue engineering in pediatric urology Curr Opin Urol. 2008 Jul; 18(4):404-7. . View in PubMed

Stem cell and regenerative science applications in the development of bioengineering of renal tissue Pediatr Res. 2008 May; 63(5):467-71. . View in PubMed

Ex vivo whole embryonic kidney culture: a novel method for research in development, regeneration and transplantation J Urol. 2008 Jan; 179(1):365-70. . View in PubMed

Characterization of human amniotic fluid stem cells and their pluripotential capability Methods Cell Biol. 2008; 86:85-99. . View in PubMed

Renal differentiation of amniotic fluid stem cells Cell Prolif. 2007 Dec; 40(6):936-48. . View in PubMed

Isolation of amniotic stem cell lines with potential for therapy Nat Biotechnol. 2007 Jan; 25(1):100-6. . View in PubMed

Tissue engineering of a small hand phalanx with a porously casted polylactic acid-polyglycolic acid copolymer Tissue Eng. 2006 Sep; 12(9):2675-83. . View in PubMed

Propagation, expansion, and multilineage differentiation of human somatic stem cells from dermal progenitors Stem Cells Dev. 2005 Jun; 14(3):337-48. . View in PubMed

Autologous satellite cell seeding improves in vivo biocompatibility of homologous muscle acellular matrix implants Int J Mol Med. 2002 Aug; 10(2):177-82. . View in PubMed

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