Faculty

Cheng-Ming Chuong

Cheng-Ming Chuong

Professor of Pathology;Director of Graduate Programs
Pathology
HMR 2011 Zonal Ave Health Sciences Campus Los Angeles

Regulation and dysregulation of hair regeneration: aiming for clinical application Cell Regen. 2022 Jul 01; 11(1):22. . View in PubMed

Successful Repigmentation of Full-Thickness Wound Healing in Fraser's Dolphins (Lagenodelphis hosei) Animals (Basel). 2022 Jun 08; 12(12). . View in PubMed

Defining Wound Healing Progression in Cetacean Skin: Characteristics of Full-Thickness Wound Healing in Fraser's Dolphins (Lagenodelphis hosei) Animals (Basel). 2022 Feb 22; 12(5). . View in PubMed

Corrigendum to "The crest phenotype in domestic chicken is caused by a 195 bp duplication in the intron of HOXC10" G3 (Bethesda). 2022 Feb 04; 12(2). . View in PubMed

Regional specific differentiation of integumentary organs: SATB2 is involved in a- and ß-keratin gene cluster switching in the chicken Dev Dyn. 2022 09; 251(9):1490-1508. . View in PubMed

Global feather orientations changed by electric current iScience. 2021 Jun 25; 24(6):102671. . View in PubMed

The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages Biol Rev Camb Philos Soc. 2021 12; 96(6):2573-2583. . View in PubMed

The feather pattern autosomal barring in chicken is strongly associated with segregation at the MC1R locus Pigment Cell Melanoma Res. 2021 11; 34(6):1015-1028. . View in PubMed

Making region-specific integumentary organs in birds: evolution and modifications Curr Opin Genet Dev. 2021 08; 69:103-111. . View in PubMed

Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice Nat Commun. 2021 05 10; 12(1):2595. . View in PubMed

Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging Front Cell Dev Biol. 2021; 9:635340. . View in PubMed

A quantitative image-based protocol for morphological characterization of cellular solids in feather shafts STAR Protoc. 2021 09 17; 2(3):100661. . View in PubMed

Regional Specific Differentiation of Integumentary Organs: Regulation of Gene Clusters within the Avian Epidermal Differentiation Complex and Impacts of SATB2 Overexpression Genes (Basel). 2021 08 23; 12(8). . View in PubMed

The crest phenotype in domestic chicken is caused by a 197 bp duplication in the intron of HOXC10 G3 (Bethesda). 2021 02 09; 11(2). . View in PubMed

Cis-acting mutation affecting GJA5 transcription is underlying the Melanotic within-feather pigmentation pattern in chickens Proc Natl Acad Sci U S A. 2021 10 12; 118(41). . View in PubMed

Editorial: Hair Follicle Stem Cell Regeneration in Aging Front Cell Dev Biol. 2021; 9:799268. . View in PubMed

Cyclic growth of dermal papilla and regeneration of follicular mesenchymal components during feather cycling Development. 2021 09 15; 148(18). . View in PubMed

Integrating Bioelectrical Currents and Ca2+ Signaling with Biochemical Signaling in Development and Pathogenesis Bioelectricity. 2020 Sep 01; 2(3):210-220. . View in PubMed

Variations of Mesozoic feathers: Insights from the morphogenesis of extant feather rachises Evolution. 2020 09; 74(9):2121-2133. . View in PubMed

Development of injectable chitosan/biphasic calcium phosphate bone cement and in vitro and in vivo evaluation Biomed Mater. 2020 09 08; 15(5):055038. . View in PubMed

Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells Front Cell Dev Biol. 2020; 8:583434. . View in PubMed

Niche Modulation of IGF-1R Signaling: Its Role in Stem Cell Pluripotency, Cancer Reprogramming, and Therapeutic Applications Front Cell Dev Biol. 2020; 8:625943. . View in PubMed

Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures Front Cell Dev Biol. 2020; 8:628114. . View in PubMed

The Effects of Premature Tooth Extraction and Damage on Replacement Timing in the Green Iguana Integr Comp Biol. 2020 09 01; 60(3):581-593. . View in PubMed

Connectivity between nidopallium caudolateral and visual pathways in color perception of zebra finches Sci Rep. 2020 11 09; 10(1):19382. . View in PubMed

Avian Pigment Pattern Formation: Developmental Control of Macro- (Across the Body) and Micro- (Within a Feather) Level of Pigment Patterns Front Cell Dev Biol. 2020; 8:620. . View in PubMed

Folding Keratin Gene Clusters during Skin Regional SpecificationDev Cell. 2020 06 08; 53(5):561-576. e9. . View in PubMed

PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo Cells. 2019 Dec 30; 9(1). . View in PubMed

Understanding skin morphogenesis across developmental, regenerative and evolutionary levels Exp Dermatol. 2019 04; 28(4):327-331. . View in PubMed

Regeneration of rete ridges in Lanyu pig (Sus scrofa): Insights for human skin wound healing Exp Dermatol. 2019 04; 28(4):472-479. . View in PubMed

The tension biology of wound healing Exp Dermatol. 2019 04; 28(4):464-471. . View in PubMed

Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials Exp Dermatol. 2019 04; 28(4):395-405. . View in PubMed

Comparative regenerative biology of spiny (Acomys cahirinus) and laboratory (Mus musculus) mouse skin Exp Dermatol. 2019 04; 28(4):442-449. . View in PubMed

Self-organizing hair peg-like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field Exp Dermatol. 2019 04; 28(4):355-366. . View in PubMed

STAT3 signalling pathway is implicated in keloid pathogenesis by preliminary transcriptome and open chromatin analyses Exp Dermatol. 2019 04; 28(4):480-484. . View in PubMed

Turing patterning with and without a global wave PLoS Biol. 2019 03; 17(3):e3000195. . View in PubMed

Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis Nat Commun. 2019 05 20; 10(1):2226. . View in PubMed

The Making of a Flight Feather: Bio-architectural Principles and AdaptationCell. 2019 11 27; 179(6):1409-1423. e17. . View in PubMed

Instructive role of melanocytes during pigment pattern formation of the avian skin Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6884-6890. . View in PubMed

Self-assembly of biological networks via adaptive patterning revealed by avian intradermal muscle network formation Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10858-10867. . View in PubMed

Morpho-regulation in diverse chicken feather formation: Integrating branching modules and sex hormone-dependent morpho-regulatory modules Dev Growth Differ. 2019 Jan; 61(1):124-138. . View in PubMed

Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification BMC Genomics. 2018 Oct 29; 19(1):780. . View in PubMed

Msx2 Supports Epidermal Competency during Wound-Induced Hair Follicle Neogenesis J Invest Dermatol. 2018 09; 138(9):2041-2050. . View in PubMed

Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation JCI Insight. 2018 07 12; 3(13). . View in PubMed

Multiple Regulatory Modules Are Required for Scale-to-Feather Conversion Mol Biol Evol. 2018 02 01; 35(2):417-430. . View in PubMed

Comprehensive molecular and cellular studies suggest avian scutate scales are secondarily derived from feathers, and more distant from reptilian scales Sci Rep. 2018 11 13; 8(1):16766. . View in PubMed

Contraction of basal filopodia controls periodic feather branching via Notch and FGF signaling Nat Commun. 2018 04 09; 9(1):1345. . View in PubMed

Comparative genomics and transcriptomics of Chrysolophus provide insights into the evolution of complex plumage coloration Gigascience. 2018 10 01; 7(10). . View in PubMed

Epidermal Darwinism and Competitive Equilibrium within the Epidermis Cell Stem Cell. 2018 11 01; 23(5):627-629. . View in PubMed

Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks Nat Commun. 2018 12 18; 9(1):5377. . View in PubMed

Genetic Mapping and Biochemical Basis of Yellow Feather Pigmentation in BudgerigarsCell. 2017 Oct 05; 171(2):427-439. e21. . View in PubMed

Getting to the Core of the Dermal Papilla J Invest Dermatol. 2017 11; 137(11):2250-2253. . View in PubMed

Heterochronic truncation of odontogenesis in theropod dinosaurs provides insight into the macroevolution of avian beaks Proc Natl Acad Sci U S A. 2017 10 10; 114(41):10930-10935. . View in PubMed

Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells Proc Natl Acad Sci U S A. 2017 08 22; 114(34):E7101-E7110. . View in PubMed

The GCaMP-R Family of Genetically Encoded Ratiometric Calcium Indicators ACS Chem Biol. 2017 04 21; 12(4):1066-1074. . View in PubMed

Diverse feather shape evolution enabled by coupling anisotropic signalling modules with self-organizing branching programme Nat Commun. 2017 01 20; 8:ncomms14139. . View in PubMed

MicroCT Imaging on Living Alligator Teeth Reveals Natural Tooth Cycling Methods Mol Biol. 2017; 1650:355-362. . View in PubMed

Systems Biology Analyses in Chicken: Workflow for Transcriptome and ChIP-Seq Analyses Using the Chicken Skin Paradigm Methods Mol Biol. 2017; 1650:87-100. . View in PubMed

The Molecular Circuit Regulating Tooth Development in Crocodilians J Dent Res. 2016 Dec; 95(13):1501-1510. . View in PubMed

The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration J Mol Biol. 2016 Apr 10; 428(7):1423-40. . View in PubMed

STEM CELLSAging, alopecia, and stem cells. Science. 2016 Feb 05; 351(6273):559-60. . View in PubMed

Quorum sensing and other collective regenerative behavior in organ populations Curr Opin Genet Dev. 2016 10; 40:138-143. . View in PubMed

Regulatory Differences in Natal Down Development between Altricial Zebra Finch and Precocial Chicken Mol Biol Evol. 2016 08; 33(8):2030-43. . View in PubMed

The "tao" of integuments Science. 2016 12 23; 354(6319):1533-1534. . View in PubMed

Corrigendum: Assembling Composite Dermal Papilla Spheres with Adipose-derived Stem Cells to Enhance Hair Follicle Induction Sci Rep. 2016 11 14; 6:31257. . View in PubMed

Assembling Composite Dermal Papilla Spheres with Adipose-derived Stem Cells to Enhance Hair Follicle Induction Sci Rep. 2016 05 23; 6:26436. . View in PubMed

Topographical mapping of a- and ß-keratins on developing chicken skin integuments: Functional interaction and evolutionary perspectives Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):E6770-9. . View in PubMed

Proper BMP Signaling Levels Are Essential for 3D Assembly of Hepatic Cords from Hepatoblasts and Mesenchymal Cells Dig Dis Sci. 2015 Dec; 60(12):3669-80. . View in PubMed

Transcriptomic analyses of regenerating adult feathers in chicken BMC Genomics. 2015 Oct 06; 16:756. . View in PubMed

Prolonged overexpression of Wnt10b induces epidermal keratinocyte transformation through activating EGF pathway Histochem Cell Biol. 2015 Sep; 144(3):209-21. . View in PubMed

Roles of GasderminA3 in Catagen-Telogen Transition During Hair Cycling J Invest Dermatol. 2015 Sep; 135(9):2162-2172. . View in PubMed

Evolution and functional significance of derived sternal ossification patterns in ornithothoracine birds J Evol Biol. 2015 Aug; 28(8):1550-67. . View in PubMed

Deciphering principles of morphogenesis from temporal and spatial patterns on the integument Dev Dyn. 2015 Aug; 244(8):905-20. . View in PubMed

Feather on the Cap of Medicine J Invest Dermatol. 2015 Jul; 135(7):1719-1721. . View in PubMed

Dynamic imaging of the growth plate cartilage reveals multiple contributors to skeletal morphogenesis Nat Commun. 2015 Apr 13; 6:6798. . View in PubMed

Organ-level quorum sensing directs regeneration in hair stem cell populations Cell. 2015 Apr 09; 161(2):277-90. . View in PubMed

Perivascular-derived stem cells with neural crest characteristics are involved in tendon repair Stem Cells Dev. 2015 Apr 01; 24(7):857-68. . View in PubMed

Emergence of differentially regulated pathways associated with the development of regional specificity in chicken skin BMC Genomics. 2015 Jan 23; 16:22. . View in PubMed

Development, regeneration, and evolution of feathers Annu Rev Anim Biosci. 2015; 3:169-95. . View in PubMed

An integrative approach to understanding bird origins Science. 2014 Dec 12; 346(6215):1253293. . View in PubMed

Bifunctional ectodermal stem cells around the nail display dual fate homeostasis and adaptive wounding response toward nail regeneration Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):15114-9. . View in PubMed

Defining dermal adipose tissue Exp Dermatol. 2014 Sep; 23(9):629-31. . View in PubMed

SnapShot: Branching MorphogenesisCell. 2014 Aug 28; 158(5):1212-1212. e1. . View in PubMed

Genomic organization, transcriptomic analysis, and functional characterization of avian a- and ß-keratins in diverse feather forms Genome Biol Evol. 2014 Aug 24; 6(9):2258-73. . View in PubMed

Regenerative hair waves in aging mice and extra-follicular modulators follistatin, dkk1, and sfrp4 J Invest Dermatol. 2014 Aug; 134(8):2086-2096. . View in PubMed

Ultrastructural characteristics of 5BrdU labeling retention cells including stem cells of regenerating feathers in chicken J Morphol. 2014 Jul; 275(7):768-74. . View in PubMed

Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration Exp Dermatol. 2014 Jun; 23(6):407-13. . View in PubMed

Dkk2/Frzb in the dermal papillae regulates feather regeneration Dev Biol. 2014 Mar 15; 387(2):167-78. . View in PubMed

Regeneration of reptilian scales after wounding: neogenesis, regional difference, and molecular modules Regeneration (Oxf). 2014 Feb 01; 1(1):15-26. . View in PubMed

Macroenvironmental regulation of hair cycling and collective regenerative behavior Cold Spring Harb Perspect Med. 2014 Jan 01; 4(1):a015198. . View in PubMed

Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis J Invest Dermatol. 2014 Jan; 134(1):24-32. . View in PubMed

Environmental reprogramming and molecular profiling in reconstitution of human hair follicles Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19658-9. . View in PubMed

Nuclear topology, epigenetics, and keratinocyte differentiation J Invest Dermatol. 2013 Sep; 133(9):2130-3. . View in PubMed

Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge Science. 2013 Jun 21; 340(6139):1442-5. . View in PubMed

Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling Proc Natl Acad Sci U S A. 2013 Jun 04; 110(23):E2106-15. . View in PubMed

Many paths to alopecia via compromised regeneration of hair follicle stem cells J Invest Dermatol. 2013 Jun; 133(6):1450-2. . View in PubMed

Specialized stem cell niche enables repetitive renewal of alligator teeth Proc Natl Acad Sci U S A. 2013 May 28; 110(22):E2009-18. . View in PubMed

Shaping organs by a wingless-int/Notch/nonmuscle myosin module which orients feather bud elongation Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):E1452-61. . View in PubMed

Sox2 marks epithelial competence to generate teeth in mammals and reptiles Development. 2013 Apr; 140(7):1424-32. . View in PubMed

Therapeutic strategy for hair regeneration: hair cycle activation, niche environment modulation, wound-induced follicle neogenesis, and stem cell engineering Expert Opin Biol Ther. 2013 Mar; 13(3):377-91. . View in PubMed

Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1351-6. . View in PubMed

Module-based complexity formation: periodic patterning in feathers and hairs Wiley Interdiscip Rev Dev Biol. 2013 Jan-Feb; 2(1):97-112. . View in PubMed

Feather regeneration as a model for organogenesis Dev Growth Differ. 2013 Jan; 55(1):139-48. . View in PubMed

Tuning Wnt signals for more or fewer hairs J Invest Dermatol. 2013 Jan; 133(1):7-9. . View in PubMed

Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1 J Invest Dermatol. 2012 Dec; 132(12):2681-90. . View in PubMed

Sprouty/FGF signaling regulates the proximal-distal feather morphology and the size of dermal papillae Dev Biol. 2012 Dec 01; 372(1):45-54. . View in PubMed

Homology and Potential Cellular and Molecular Mechanisms for the Development of Unique Feather Morphologies in Early Birds Geosciences (Basel). 2012 Sep 14; 2(3):157-177. . View in PubMed

Multi-layered environmental regulation on the homeostasis of stem cells: the saga of hair growth and alopecia J Dermatol Sci. 2012 Apr; 66(1):3-11. . View in PubMed

Physiological regeneration of skin appendages and implications for regenerative medicine Physiology (Bethesda). 2012 Apr; 27(2):61-72. . View in PubMed

Patterning skin by planar cell polarity: the multi-talented hair designer Exp Dermatol. 2012 Feb; 21(2):81-5. . View in PubMed

The chicken frizzle feather is due to an a-keratin (KRT75) mutation that causes a defective rachis PLoS Genet. 2012; 8(7):e1002748. . View in PubMed

Modelling hair follicle growth dynamics as an excitable medium PLoS Comput Biol. 2012; 8(12):e1002804. . View in PubMed

Roles of EphB3/ephrin-B1 in feather morphogenesis Int J Dev Biol. 2012; 56(9):719-28. . View in PubMed

Toward the isolation and culture of melanocyte stem cells J Invest Dermatol. 2011 Dec; 131(12):2341-3. . View in PubMed

PI3K, Erk signaling in BMP7-induced epithelial-mesenchymal transition (EMT) of PC-3 prostate cancer cells in 2- and 3-dimensional cultures Horm Cancer. 2011 Oct; 2(5):298-309. . View in PubMed

From buds to follicles: matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis Differentiation. 2011 Jun; 81(5):307-14. . View in PubMed

Self-organizing and stochastic behaviors during the regeneration of hair stem cells Science. 2011 Apr 29; 332(6029):586-9. . View in PubMed

A simplified procedure to reconstitute hair-producing skin Tissue Eng Part C Methods. 2011 Apr; 17(4):391-400. . View in PubMed

In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages Integr Biol (Camb). 2011 Apr; 3(4):388-407. . View in PubMed

The cycling hair follicle as an ideal systems biology research model Exp Dermatol. 2010 Aug; 19(8):707-13. . View in PubMed

Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation Dev Biol. 2009 Oct 15; 334(2):369-82. . View in PubMed

Accelerated closure of skin wounds in mice deficient in the homeobox gene Msx2 Wound Repair Regen. 2009 Sep-Oct; 17(5):639-48. . View in PubMed

Building complex tissues: high-throughput screening for molecules required in hair engineering J Invest Dermatol. 2009 Apr; 129(4):815-7. . View in PubMed

The river of stem cells Cell Stem Cell. 2009 Feb 06; 4(2):100-2. . View in PubMed

Preface to pattern formation special issue Int J Dev Biol. 2009; 53(5-6):651. . View in PubMed

Reptile scale paradigm: Evo-Devo, pattern formation and regeneration Int J Dev Biol. 2009; 53(5-6):813-26. . View in PubMed

Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity Int J Dev Biol. 2009; 53(5-6):857-68. . View in PubMed

Pattern formation today Int J Dev Biol. 2009; 53(5-6):653-8. . View in PubMed

Regenerative patterning in Swarm Robots: mutual benefits of research in robotics and stem cell biology Int J Dev Biol. 2009; 53(5-6):869-81. . View in PubMed

Conversion of the nipple to hair-bearing epithelia by lowering bone morphogenetic protein pathway activity at the dermal-epidermal interface Am J Pathol. 2008 Nov; 173(5):1339-48. . View in PubMed

Complex hair cycle domain patterns and regenerative hair waves in living rodents J Invest Dermatol. 2008 May; 128(5):1071-80. . View in PubMed

Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration Nature. 2008 Jan 17; 451(7176):340-4. . View in PubMed

Defining hair follicles in the age of stem cell bioengineering J Invest Dermatol. 2007 Sep; 127(9):2098-100. . View in PubMed

An integrated gene regulatory network controls stem cell proliferation in teeth PLoS Biol. 2007 Jun; 5(6):e159. . View in PubMed

Regenerative biology: new hair from healing wounds Nature. 2007 May 17; 447(7142):265-6. . View in PubMed

The Edar subfamily in feather placode formation Dev Biol. 2007 May 01; 305(1):232-45. . View in PubMed

Mammary glands and feathers: comparing two skin appendages which help define novel classes during vertebrate evolution Semin Cell Dev Biol. 2007 Apr; 18(2):255-66. . View in PubMed

Molecular signaling in feather morphogenesis Curr Opin Cell Biol. 2006 Dec; 18(6):730-41. . View in PubMed

Developmental biologyThe Turing model comes of molecular age. Science. 2006 Dec 01; 314(5804):1397-8. . View in PubMed

PubFocus: semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algorithm BMC Bioinformatics. 2006 Oct 02; 7:424. . View in PubMed

Distinct mechanisms underlie pattern formation in the skin and skin appendages Birth Defects Res C Embryo Today. 2006 Sep; 78(3):280-91. . View in PubMed

What is the biological basis of pattern formation of skin lesions? Exp Dermatol. 2006 Jul; 15(7):547-64.. View in PubMed

Morphoregulation of avian beaks: comparative mapping of growth zone activities and morphological evolution Dev Dyn. 2006 May; 235(5):1400-12. . View in PubMed

Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia Proc Natl Acad Sci U S A. 2006 Jan 24; 103(4):951-5. . View in PubMed

Engineering stem cells into organs: topobiological transformations demonstrated by beak, feather, and other ectodermal organ morphogenesis Curr Top Dev Biol. 2006; 72:237-74. . View in PubMed

Mapping stem cell activities in the feather follicle Nature. 2005 Dec 15; 438(7070):1026-9. . View in PubMed

Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity Evol Dev. 2005 Sep-Oct; 7(5):440-57. . View in PubMed

Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: what is in common? Differentiation. 2004 Dec; 72(9-10):474-88.. View in PubMed

Molecular shaping of the beak Science. 2004 Sep 03; 305(5689):1465-6. . View in PubMed

Sculpting skin appendages out of epidermal layers via temporally and spatially regulated apoptotic events J Invest Dermatol. 2004 Jun; 122(6):1348-55. . View in PubMed

Making waves with hairs J Invest Dermatol. 2004 Apr; 122(4):vii-ix. . View in PubMed

Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway Am J Pathol. 2004 Mar; 164(3):1099-114. . View in PubMed

Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation Dev Biol. 2004 Feb 01; 266(1):109-22. . View in PubMed

Distinct Wnt members regulate the hierarchical morphogenesis of skin regions (spinal tract) and individual feathers Mech Dev. 2004 Feb; 121(2):157-71. . View in PubMed

The biology of feather follicles Int J Dev Biol. 2004; 48(2-3):181-91. . View in PubMed

Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models Int J Dev Biol. 2004; 48(2-3):117-35. . View in PubMed

Evo-Devo of amniote integuments and appendages Int J Dev Biol. 2004; 48(2-3):249-70. . View in PubMed

New Early Cretaceous fossil from China documents a novel trophic specialization for Mesozoic birds Naturwissenschaften. 2004 Jan; 91(1):22-5. . View in PubMed

A mouthful of epithelial-mesenchymal interactions J Invest Dermatol. 2003 Dec; 121(6):vii-viii. . View in PubMed

Development and evolution of the amniote integument: current landscape and future horizon J Exp Zool B Mol Dev Evol. 2003 Aug 15; 298(1):1-11. . View in PubMed

Molecular biology of feather morphogenesis: a testable model for evo-devo research J Exp Zool B Mol Dev Evol. 2003 Aug 15; 298(1):109-22. . View in PubMed

Adaptation to the sky: Defining the feather with integument fossils from mesozoic China and experimental evidence from molecular laboratories J Exp Zool B Mol Dev Evol. 2003 Aug 15; 298(1):42-56. . View in PubMed

'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation Development. 2003 Jan; 130(2):379-89. . View in PubMed

Homeobox genes, fetal wound healing, and skin regional specificity J Invest Dermatol. 2003 Jan; 120(1):9-11. . View in PubMed

Shift of localized growth zones contributes to skin appendage morphogenesis: role of the Wnt/beta-catenin pathway J Invest Dermatol. 2003 Jan; 120(1):20-6. . View in PubMed

The morphogenesis of feathers Nature. 2002 Nov 21; 420(6913):308-12. . View in PubMed

Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators J Biol Chem. 2002 Jul 19; 277(29):26031-5. . View in PubMed

What is the 'true' function of skin? Exp Dermatol. 2002 Apr; 11(2):159-87.. View in PubMed

D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections Curr Cancer Drug Targets. 2001 Nov; 1(3):241-7. . View in PubMed

Eur J Dermatol. 2001 Jul-Aug; 11(4):286-92. . View in PubMed

Immunohistochemical localization of deleted-in-colon-cancer (DCC) protein in human epithelial, neural, and neuro-endocrine tissues in paraffin sections with antigen retrieval Kaohsiung J Med Sci. 2001 Jun; 17(7):351-7. . View in PubMed

A Novel mRNA-cDNA interference phenomenon for silencing bcl-2 expression in human LNCaP cells Biochem Biophys Res Commun. 2001 Mar 02; 281(3):639-44. . View in PubMed

Sonic hedgehog signaling pathway in vertebrate epithelial appendage morphogenesis: perspectives in development and evolution Cell Mol Life Sci. 2000 Nov; 57(12):1672-81. . View in PubMed

Conservation of early odontogenic signaling pathways in Aves Proc Natl Acad Sci U S A. 2000 Aug 29; 97(18):10044-9. . View in PubMed

Evo-devo of feathers and scales: building complex epithelial appendages Curr Opin Genet Dev. 2000 Aug; 10(4):449-56. . View in PubMed

Dynamic expression of lunatic fringe during feather morphogenesis: a switch from medial-lateral to anterior-posterior asymmetry Mech Dev. 2000 Mar 01; 91(1-2):351-4. . View in PubMed

beta-catenin in epithelial morphogenesis: conversion of part of avian foot scales into feather buds with a mutated beta-catenin Dev Biol. 2000 Mar 01; 219(1):98-114. . View in PubMed

Retroviral gene transduction in limb bud micromass cultures Methods Mol Biol. 2000; 135:509-13. . View in PubMed

Skin morphogenesisEmbryonic chicken skin explant cultures. Methods Mol Biol. 2000; 136:101-6. . View in PubMed

Phenotypic determination of epithelial appendages: genes, developmental pathways, and evolution J Investig Dermatol Symp Proc. 1999 Dec; 4(3):307-11. . View in PubMed

Msx-2 and the regulation of organ size: epidermal thickness and hair length J Investig Dermatol Symp Proc. 1999 Dec; 4(3):278-81. . View in PubMed

In vivo analysis of cancerous gene expression by RNA-polymerase chain reaction Nucleic Acids Res. 1999 Dec 01; 27(23):4585-9. . View in PubMed

Early events in skin appendage formation: induction of epithelial placodes and condensation of dermal mesenchyme J Investig Dermatol Symp Proc. 1999 Dec; 4(3):302-6. . View in PubMed

Avian integument provides multiple possibilities to analyse different phases of skin appendage morphogenesis J Investig Dermatol Symp Proc. 1999 Dec; 4(3):333-7. . View in PubMed

Suppression of activin-induced apoptosis by novel antisense strategy in human prostate cancer cells Biochem Biophys Res Commun. 1999 Nov 30; 265(3):669-73. . View in PubMed

Self-organization of periodic patterns by dissociated feather mesenchymal cells and the regulation of size, number and spacing of primordia Development. 1999 Nov; 126(22):4997-5009. . View in PubMed

Generation of full-length cDNA library from single human prostate cancer cells Biotechniques. 1999 Sep; 27(3):410-2414. . View in PubMed

Successive formative stages of precartilaginous mesenchymal condensations in vitro: modulation of cell adhesion by Wnt-7A and BMP-2 J Cell Physiol. 1999 Sep; 180(3):314-24. . View in PubMed

Epidermal dysplasia and abnormal hair follicles in transgenic mice overexpressing homeobox gene MSX-2 J Invest Dermatol. 1999 Aug; 113(2):230-7. . View in PubMed

Wnt-7a in feather morphogenesis: involvement of anterior-posterior asymmetry and proximal-distal elongation demonstrated with an in vitro reconstitution model Development. 1999 Jun; 126(12):2577-87. . View in PubMed

Retroviral gene transfer in chondrogenic limb bud micromass cultures Biotechniques. 1998 Apr; 24(4):660-6. . View in PubMed

Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning Dev Biol. 1998 Apr 01; 196(1):11-23. . View in PubMed

Lineage and pluripotentiality of epithelial precursor cells in developing chicken skin Biochem Cell Biol. 1998; 76(6):1069-77. . View in PubMed

Expression of two Ig family adhesion molecules in the murine hair cycle: DCC in the bulge epithelia and NCAM in the follicular papilla J Invest Dermatol. 1997 Nov; 109(5):672-8. . View in PubMed

Dual action of sonic hedgehog on chondrocyte hypertrophy: retrovirus mediated ectopic sonic hedgehog expression in limb bud micromass culture induces novel cartilage nodules that are positive for alkaline phosphatase and type X collagen J Cell Sci. 1997 Nov; 110 ( Pt 21):2691-701. . View in PubMed

Isolation and characterization of chicken beta-catenin Gene. 1997 Sep 01; 196(1-2):201-7. . View in PubMed

Molecular histology in skin appendage morphogenesis Microsc Res Tech. 1997 Aug 15; 38(4):452-65. . View in PubMed

Asymmetric expression of Notch/Delta/Serrate is associated with the anterior-posterior axis of feather buds Dev Biol. 1997 Aug 01; 188(1):181-7. . View in PubMed

Activation of protein kinase A is a pivotal step involved in both BMP-2- and cyclic AMP-induced chondrogenesis J Cell Physiol. 1997 Feb; 170(2):153-65. . View in PubMed

FGF induces new feather buds from developing avian skin J Invest Dermatol. 1996 Dec; 107(6):797-803. . View in PubMed

Local delivery of TGF beta2 can substitute for placode epithelium to induce mesenchymal condensation during skin appendage morphogenesis Dev Biol. 1996 Nov 01; 179(2):347-59. . View in PubMed

Sonic Hedgehog in feather morphogenesis: induction of mesenchymal condensation and association with cell death Dev Dyn. 1996 Oct; 207(2):157-70. . View in PubMed

Early events during avian skin appendage regeneration: dependence on epithelial-mesenchymal interaction and order of molecular reappearance J Invest Dermatol. 1996 Oct; 107(4):639-46. . View in PubMed

cAMP, an activator of protein kinase A, suppresses the expression of sonic hedgehog Biochem Biophys Res Commun. 1996 Feb 06; 219(1):180-5. . View in PubMed

Protein kinase A and protein kinase C modulators have reciprocal effects on mesenchymal condensation during skin appendage morphogenesis Dev Biol. 1995 Oct; 171(2):677-93. . View in PubMed

Homeobox genes Msx-1 and Msx-2 are associated with induction and growth of skin appendages J Invest Dermatol. 1995 May; 104(5):711-9. . View in PubMed

cDCC (chicken homologue to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction Dev Biol. 1994 Aug; 164(2):383-97. . View in PubMed

Effect of in ovo retinoic acid exposure on forebrain neural crest: in vitro analysis reveals up-regulation of N-CAM and loss of mesenchymal phenotype Dev Dyn. 1994 Jun; 200(2):89-102. . View in PubMed

Tenascin is associated with articular cartilage development Dev Dyn. 1993 Oct; 198(2):123-34. . View in PubMed

Asymmetric patterns of gap junctional communication in developing chicken skin Development. 1993 Sep; 119(1):85-96. . View in PubMed

Adhesion molecules in skeletogenesis: IINeural cell adhesion molecules mediate precartilaginous mesenchymal condensations and enhance chondrogenesis. J Cell Physiol. 1993 Aug; 156(2):399-411. . View in PubMed

The making of a feather: homeoproteins, retinoids and adhesion molecules Bioessays. 1993 Aug; 15(8):513-21. . View in PubMed

Design of compact multiple cloning sites Biotechniques. 1993 Aug; 15(2):208210-2214. . View in PubMed

Adhesion molecules and homeoproteins in the phenotypic determination of skin appendages J Invest Dermatol. 1993 Jul; 101(1 Suppl):10S-15S. . View in PubMed

Activin enhances chondrogenesis of limb bud cells: stimulation of precartilaginous mesenchymal condensations and expression of NCAM Dev Biol. 1993 Feb; 155(2):545-57. . View in PubMed

Roles of adhesion molecules NCAM and tenascin in limb skeletogenesis: analysis with antibody perturbation, exogenous gene expression, talpid mutants and activin stimulation Prog Clin Biol Res. 1993; 383B:465-74. . View in PubMed

Adhesion molecules in skeletogenesis: ITransient expression of neural cell adhesion molecules (NCAM) in osteoblasts during endochondral and intramembranous ossification. J Bone Miner Res. 1992 Dec; 7(12):1435-46. . View in PubMed

Replication-defective virus infection of feather buds produces a localized region of beta-galactosidase activity Biochem Biophys Res Commun. 1992 Jul 31; 186(2):1020-4. . View in PubMed

Mechanism of skin morphogenesisII. Retinoic acid modulates axis orientation and phenotypes of skin appendages. Development. 1992 Jul; 115(3):839-52. . View in PubMed

Mechanism of skin morphogenesisI. Analyses with antibodies to adhesion molecules tenascin, N-CAM, and integrin. Dev Biol. 1992 Mar; 150(1):82-98. . View in PubMed

Adhesion molecules in skin development: morphogenesis of feather and hair Ann N Y Acad Sci. 1991 Dec 26; 642:263-80. . View in PubMed

Position-specific expression of homeoprotein gradients in different feather tracts Ann N Y Acad Sci. 1991 Dec 26; 642:462-4. . View in PubMed

Enhanced expression of neural cell adhesion molecules and tenascin (cytotactin) during wound healing Am J Pathol. 1991 Feb; 138(2):427-40. . View in PubMed

Gradients of homeoproteins in developing feather buds Development. 1990 Dec; 110(4):1021-30. . View in PubMed

Differential roles of multiple adhesion molecules in cell migration: granule cell migration in cerebellum Experientia. 1990 Sep 15; 46(9):892-9. . View in PubMed

Adhesion molecules (N-CAM and tenascin) in embryonic development and tissue regeneration J Craniofac Genet Dev Biol. 1990; 10(2):147-61. . View in PubMed

Alterations in the Xenopus retinotectal projection by antibodies to Xenopus N-CAM Dev Biol. 1988 Sep; 129(1):217-30. . View in PubMed

Sequential expression and differential function of multiple adhesion molecules during the formation of cerebellar cortical layers J Cell Biol. 1987 Feb; 104(2):331-42. . View in PubMed

Expression of cell adhesion molecules during embryonic inductionIII. Development of the otic placode. Dev Biol. 1987 Jan; 119(1):217-30. . View in PubMed

Antibodies to liver cell adhesion molecule perturb inductive interactions and alter feather pattern and structure Proc Natl Acad Sci U S A. 1986 Nov; 83(21):8235-9. . View in PubMed

Differential contributions of Ng-CAM and N-CAM to cell adhesion in different neural regions J Cell Biol. 1986 Jul; 103(1):145-58. . View in PubMed

Differential distribution of cell adhesion molecules during histogenesis of the chick nervous system J Neurosci. 1986 Mar; 6(3):739-58. . View in PubMed

Expression sequences of cell adhesion molecules Proc Natl Acad Sci U S A. 1985 Oct; 82(20):6942-6. . View in PubMed

Expression of cell-adhesion molecules in embryonic inductionI. Morphogenesis of nestling feathers. J Cell Biol. 1985 Sep; 101(3):1009-26. . View in PubMed

Expression of cell-adhesion molecules in embryonic inductionII. Morphogenesis of adult feathers. J Cell Biol. 1985 Sep; 101(3):1027-43. . View in PubMed

Polypeptide components and binding functions of neuron-glia cell adhesion molecules Proc Natl Acad Sci U S A. 1984 Dec; 81(24):7989-93. . View in PubMed

Evolutionary conservation of key structures and binding functions of neural cell adhesion molecules Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6881-5. . View in PubMed

Alterations in neural cell adhesion molecules during development of different regions of the nervous system J Neurosci. 1984 Sep; 4(9):2354-68. . View in PubMed

Alteration of the retinotectal map in Xenopus by antibodies to neural cell adhesion molecules Proc Natl Acad Sci U S A. 1984 Jul; 81(13):4222-6. . View in PubMed

Structure and modulation of neural cell adhesion molecules in early and late embryogenesis Cold Spring Harb Symp Quant Biol. 1983; 48 Pt 2:515-26. . View in PubMed

Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice Proc Natl Acad Sci U S A. 1982 Nov; 79(22):7036-40. . View in PubMed

Neural cell adhesion molecules in rodent brains isolated by monoclonal antibodies with cross-species reactivity Proc Natl Acad Sci U S A. 1982 Jul; 79(13):4234-8. . View in PubMed

sc ctsi logoPowered by SC CTSI

Affiliated Faculty at UPC