Donald Barkauskas

Donald Barkauskas

Associate Professor of Clinical Preventive Medicine
Preventive Medicine
2001 N. Soto Street Health Sciences Campus Los Angeles

ADVL1522: A phase 2 study of lorvotuzumab mertansine (IMGN901) in children with relapsed or refractory wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, malignant peripheral nerve sheath tumor, or synovial sarcoma-A Children's Oncology Group study Cancer. 2020 Sep 11. . View in PubMed

High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers Mol Cancer Ther. 2020 Aug 03. . View in PubMed

Tumor mutational burden is not predictive of cytotoxic chemotherapy response Oncoimmunology. 2020 Jun 24; 9(1):1781997. . View in PubMed

Relationship between protein biomarkers of chemotherapy response and microsatellite status, tumor mutational burden and PD-L1 expression in cancer patients Int J Cancer. 2020 Jun 01; 146(11):3087-3097. . View in PubMed

Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients With Osteosarcoma JAMA Oncol. 2020 Mar 19. . View in PubMed

Targeting fusions for improved outcomes in oncology treatment Cancer. 2020 Mar 15; 126(6):1315-1321. . View in PubMed

Rituximab for High-Risk, Mature B-Cell Non-Hodgkin's Lymphoma in Children N Engl J Med. 2020 06 04; 382(23):2207-2219. . View in PubMed

Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds Oncoimmunology. 2020; 9(1):1710052. . View in PubMed

Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group Br J Cancer. 2019 Apr; 120(8):869. . View in PubMed

Relations of combat stress and posttraumatic stress disorder to 24-h plasma and cerebrospinal fluid interleukin-6 levels and circadian rhythmicity Psychoneuroendocrinology. 2019 02; 100:237-245. . View in PubMed

Factors influencing survival after recurrence in osteosarcoma: A report from the Children's Oncology Group Pediatr Blood Cancer. 2019 01; 66(1):e27444. . View in PubMed

A Phase II Study of Alisertib in Children with Recurrent/Refractory Solid Tumors or Leukemia: Children's Oncology Group Phase I and Pilot Consortium (ADVL0921) Clin Cancer Res. 2019 06 01; 25(11):3229-3238. . View in PubMed

Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children's Oncology Group Cardiooncology. 2019; 5:15. . View in PubMed

Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups J Clin Oncol. 2018 Oct 23; JCO2018789388. . View in PubMed

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group Br J Cancer. 2018 08; 119(5):615-621. . View in PubMed

Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients Int J Cancer. 2018 04 15; 142(8):1594-1601. . View in PubMed

The prognostic significance of circulating serum amyloid A and CXC chemokine ligand 4 in osteosarcoma Pediatr Blood Cancer. 2017 Dec; 64(12). . View in PubMed

Biomarker significance of plasma and tumor miR-21, miR-221, and miR-106a in osteosarcoma Oncotarget. 2017 Nov 14; 8(57):96738-96752. . View in PubMed

Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate Clin Cancer Res. 2017 Aug 01; 23(15):4242-4250. . View in PubMed

Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation PLoS One. 2017; 12(7):e0181204. . View in PubMed

A novel prognostic model for osteosarcoma using circulating CXCL10 and FLT3LG Cancer. 2017 Jan 01; 123(1):144-154. . View in PubMed

Prospective Associations Between Traumatic Brain Injury and Postdeployment Tinnitus in Active-Duty Marines J Head Trauma Rehabil. 2016 Jan-Feb; 31(1):30-9. . View in PubMed

Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group Clin Cancer Res. 2016 07 15; 22(14):3643-50. . View in PubMed

p27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma Cancer Res. 2016 07 01; 76(13):4002-11. . View in PubMed

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types J Natl Cancer Inst. 2015 Dec; 107(12):djv279. . View in PubMed

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma Cancer Discov. 2015 Sep; 5(9):920-31. . View in PubMed

Cross-species identification of a plasma microRNA signature for detection, therapeutic monitoring, and prognosis in osteosarcoma Cancer Med. 2015 Jul; 4(7):977-88. . View in PubMed

Germline TP53 variants and susceptibility to osteosarcoma J Natl Cancer Inst. 2015 Jul; 107(7). . View in PubMed

Gene Expression Profiling of Ewing Sarcoma Tumors Reveals the Prognostic Importance of Tumor-Stromal Interactions: A Report from the Children's Oncology Group J Pathol Clin Res. 2015 Apr; 1(2):83-94. . View in PubMed

The Serum Immunoglobulin G Glycosylation Signature of Gastric Cancer EuPA Open Proteom. 2015 Mar 01; 6:1-9. . View in PubMed

Systemic levels of neuropeptide Y and dipeptidyl peptidase activity in patients with Ewing sarcoma--associations with tumor phenotype and survival Cancer. 2015 Mar 01; 121(5):697-707. . View in PubMed

A summary of the osteosarcoma banking efforts: a report from the Children's Oncology Group and the QuadW Foundation Pediatr Blood Cancer. 2015 Mar; 62(3):450-5. . View in PubMed

Predictive properties of DNA methylation patterns in primary tumor samples for osteosarcoma relapse status Epigenetics. 2015; 10(1):31-9. . View in PubMed

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p1533. Hum Mol Genet. 2014 Dec 15; 23(24):6616-33. . View in PubMed

The cumulative effect of different childhood trauma types on self-reported symptoms of adult male depression and PTSD, substance abuse and health-related quality of life in a large active-duty military cohort J Psychiatr Res. 2014 Nov; 58:46-54. . View in PubMed

HER-2 expression is not prognostic in osteosarcoma; a Children's Oncology Group prospective biology study Pediatr Blood Cancer. 2014 Sep; 61(9):1558-64. . View in PubMed

Circadian rhythmicity, variability and correlation of interleukin-6 levels in plasma and cerebrospinal fluid of healthy men Psychoneuroendocrinology. 2014 Jun; 44:71-82. . View in PubMed

Response to "High BMI at diagnosis is associated with inferior survival in patients with osteosarcoma" Pediatr Blood Cancer. 2014 May; 61(5):951. . View in PubMed

Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk JAMA Psychiatry. 2014 Apr; 71(4):423-31. . View in PubMed

Analysis of serum insulin growth factor-1 concentrations in localized osteosarcoma: a children's oncology group study Pediatr Blood Cancer. 2014 Apr; 61(4):749-52. . View in PubMed

Serum glycan signatures of gastric cancer Cancer Prev Res (Phila). 2014 Feb; 7(2):226-35. . View in PubMed

Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines JAMA Psychiatry. 2014 Feb; 71(2):149-57. . View in PubMed

High-BMI at diagnosis is associated with inferior survival in patients with osteosarcoma: a report from the Children's Oncology Group Pediatr Blood Cancer. 2013 Dec; 60(12):2042-6. . View in PubMed

Characterization of cerebrospinal fluid (CSF) and plasma NPY levels in normal volunteers over a 24-h timeframe Psychoneuroendocrinology. 2013 Oct; 38(10):2378-82. . View in PubMed

Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma Neoplasia. 2013 Sep; 15(9):1049-63. . View in PubMed

Genome-wide association study identifies two susceptibility loci for osteosarcoma Nat Genet. 2013 Jul; 45(7):799-803. . View in PubMed

Outcome for adolescent and young adult patients with osteosarcoma: a report from the Children's Oncology Group Cancer. 2012 Sep 15; 118(18):4597-605. . View in PubMed

Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group J Clin Oncol. 2012 Jul 10; 30(20):2545-51. . View in PubMed

Poor survival for osteosarcoma of the pelvis: a report from the Children's Oncology Group Clin Orthop Relat Res. 2012 Jul; 470(7):2007-13. . View in PubMed

Detectable clonal mosaicism and its relationship to aging and cancer Nat Genet. 2012 May 06; 44(6):651-8. . View in PubMed

Investigation of the insulin-like growth factor-1 signaling pathway in localized Ewing sarcoma: a report from the Children's Oncology Group Cancer. 2011 Nov 01; 117(21):4966-76. . View in PubMed

A general-purpose baseline estimation algorithm for spectroscopic data Anal Chim Acta. 2010 Jan 11; 657(2):191-7. . View in PubMed

Analysis of MALDI FT-ICR mass spectrometry data: a time series approach Anal Chim Acta. 2009 Aug 26; 648(2):207-14. . View in PubMed

Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data Bioinformatics. 2009 Jan 15; 25(2):251-7. . View in PubMed

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