Vaia Lida Chatzi

Vaia Lida Chatzi

Professor of Preventive Medicine
Preventive Medicine
2001 N. Soto Street Health Sciences Campus Los Angeles


Harvard Medical School: Fulbright Scholarship, 2014-2014

Centre for Environmental Research, Spain: Erasmus Fellowship, 2012-2012

Department of Public Health, University of Sheffield, UK: Marie Curie Fellowship, 2003-2003

Gestational Weight Gain by Maternal Pre-pregnancy BMI and Childhood Problem Behaviours in School-Age Years: A Pooled Analysis of Two European Birth Cohorts Matern Child Health J. 2020 Oct; 24(10):1288-1298. . View in PubMed

Early life tobacco exposure and children's telomere length: The HELIX project Sci Total Environ. 2020 Apr 01; 711:135028. . View in PubMed

Associations between air pollution and pediatric eczema, rhinoconjunctivitis and asthma: A meta-analysis of European birth cohorts Environ Int. 2020 03; 136:105474. . View in PubMed

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium Diabetes Care. 2020 01; 43(1):98-105. . View in PubMed

Association between the pregnancy exposome and fetal growth Int J Epidemiol. 2020 04 01; 49(2):572-586. . View in PubMed

Association of Fish Consumption and Mercury Exposure During Pregnancy With Metabolic Health and Inflammatory Biomarkers in Children JAMA Netw Open. 2020 03 02; 3(3):e201007. . View in PubMed

A latent unknown clustering integrating multi-omics data (LUCID) with phenotypic traits Bioinformatics. 2020 02 01; 36(3):842-850. . View in PubMed

Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American and Australian cohorts BJOG. 2019 Jul; 126(8):984-995. . View in PubMed

Horm Behav. 2019 11; 116:104585. . View in PubMed

Cord Leptin is Associated with Neuropsychomotor Development in Childhood Obesity (Silver Spring). 2019 10; 27(10):1693-1702. . View in PubMed

Diet as a Source of Exposure to Environmental Contaminants for Pregnant Women and Children from Six European Countries Environ Health Perspect. 2019 10; 127(10):107005. . View in PubMed

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors Nat Genet. 2019 05; 51(5):804-814. . View in PubMed

Cytokine. 2019 05; 117:1-7. . View in PubMed

Influence of the Urban Exposome on Birth Weight Environ Health Perspect. 2019 04; 127(4):47007. . View in PubMed

Early-life exposome and lung function in children in Europe: an analysis of data from the longitudinal, population-based HELIX cohort Lancet Planet Health. 2019 02; 3(2):e81-e92. . View in PubMed

Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis PLoS Med. 2019 02; 16(2):e1002744. . View in PubMed

Lupus. 2019 Jan; 28(1):104-113. . View in PubMed

Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis JAMA. 2019 08 20; 322(7):632-641. . View in PubMed

Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes JAMA. 2019 05 07; 321(17):1702-1715. . View in PubMed

Associations of Prenatal Exposure to Cadmium With Child Growth, Obesity, and Cardiometabolic Traits Am J Epidemiol. 2019 01 01; 188(1):141-150. . View in PubMed

Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy JAMA Netw Open. 2019 10 02; 2(10):e1912902. . View in PubMed

Early-Life Environmental Exposures and Blood Pressure in Children J Am Coll Cardiol. 2019 09 10; 74(10):1317-1328. . View in PubMed

Ambient and Traffic-Related Air Pollution Exposures as Novel Risk Factors for Metabolic Dysfunction and Type 2 Diabetes Curr Epidemiol Rep. 2018 Jun; 5(2):79-91. . View in PubMed

Air pollution during pregnancy and childhood obesity risk: Potential protective effect of diet Clin Nutr ESPEN. 2018 Apr; 24:187. . View in PubMed

Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete) Eur J Nutr. 2018 Feb; 57(1):209-218. . View in PubMed

In-utero and childhood chemical exposome in six European mother-child cohorts Environ Int. 2018 12; 121(Pt 1):751-763. . View in PubMed

Is early life exposure to polyomaviruses and herpesviruses associated with obesity indices and metabolic traits in childhood? Int J Obes (Lond). 2018 09; 42(9):1590-1601.. View in PubMed

Eur Respir J. 2018 09; 52(3). . View in PubMed

Low maternal vitamin D status in pregnancy increases the risk of childhood obesity Pediatr Obes. 2018 08; 13(8):467-475. . View in PubMed

DNA methylation in childhood asthma: an epigenome-wide meta-analysis Lancet Respir Med. 2018 05; 6(5):379-388. . View in PubMed

Air pollution, weight loss and metabolic benefits of bariatric surgery: a potential model for study of metabolic effects of environmental exposures Pediatr Obes. 2018 05; 13(5):312-320. . View in PubMed

Maternal and fetal genetic contribution to gestational weight gain Int J Obes (Lond). 2018 04; 42(4):775-784. . View in PubMed

Human Early Life Exposome (HELIX) study: a European population-based exposome cohort BMJ Open. 2018 09 10; 8(9):e021311. . View in PubMed

Determinants of the urinary and serum metabolome in children from six European populations BMC Med. 2018 11 08; 16(1):202. . View in PubMed

DNA Methylome Marks of Exposure to Particulate Matter at Three Time Points in Early Life Environ Sci Technol. 2018 05 01; 52(9):5427-5437. . View in PubMed

Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania BMC Med. 2018 11 05; 16(1):201. . View in PubMed

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium Int J Epidemiol. 2018 02 01; 47(1):22-23u. . View in PubMed

Association of Early Life Exposure to Phthalates With Obesity and Cardiometabolic Traits in Childhood: Sex Specific Associations Front Public Health. 2018; 6:327. . View in PubMed

Hum Mol Genet. 2018 02 15; 27(4):742-756. . View in PubMed

Cord Blood Metabolic Signatures of Birth Weight: A Population-Based Study J Proteome Res. 2018 03 02; 17(3):1235-1247. . View in PubMed

High maternal vitamin D levels in early pregnancy may protect against behavioral difficulties at preschool age: the Rhea mother-child cohort, Crete, Greece Eur Child Adolesc Psychiatry. 2018 Jan; 27(1):79-88. . View in PubMed

Epidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece Ann Rheum Dis. 2017 Dec; 76(12):1992-2000. . View in PubMed

Effect of parental obesity and gestational diabetes on child neuropsychological and behavioral development at 4 years of age: the Rhea mother-child cohort, Crete, Greece Eur Child Adolesc Psychiatry. 2017 Jun; 26(6):703-714. . View in PubMed

Associations of cord blood metabolites with perinatal characteristics, newborn anthropometry, and cord blood hormones in project viva Metabolism. 2017 11; 76:11-22. . View in PubMed

Association of light-to-moderate alcohol drinking in pregnancy with preterm birth and birth weight: elucidating bias by pooling data from nine European cohorts Eur J Epidemiol. 2017 09; 32(9):751-764. . View in PubMed

Adherence to the Mediterranean diet during pregnancy and offspring adiposity and cardiometabolic traits in childhood Pediatr Obes. 2017 08; 12 Suppl 1:47-56. . View in PubMed

Helicobacter pylori Seropositivity and Childhood Neurodevelopment, the Rhea Birth Cohort in Crete, Greece Paediatr Perinat Epidemiol. 2017 07; 31(4):374-384. . View in PubMed

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes J Allergy Clin Immunol. 2017 02; 139(2):388-399. . View in PubMed

Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) Clin Transl Allergy. 2017; 7:5. . View in PubMed

Land Use Regression Models for Ultrafine Particles in Six European Areas Environ Sci Technol. 2017 03 21; 51(6):3336-3345. . View in PubMed

Fish and seafood consumption during pregnancy and the risk of asthma and allergic rhinitis in childhood: a pooled analysis of 18 European and US birth cohorts Int J Epidemiol. 2017 10 01; 46(5):1465-1477. . View in PubMed

Maternal depression and personality traits in association with child neuropsychological and behavioral development in preschool years: Mother-child cohort (Rhea Study) in Crete, Greece J Affect Disord. 2017 08 01; 217:89-98. . View in PubMed

Cohort Profile: The Mother-Child Cohort in Crete, Greece (Rhea Study) Int J Epidemiol. 2017 10 01; 46(5):1392-1393k. . View in PubMed

Leptin, acylcarnitine metabolites and development of adiposity in the Rhea mother-child cohort in Crete, Greece Obes Sci Pract. 2016 Dec; 2(4):471-476. . View in PubMed

Classification of neck/shoulder pain in epidemiological research: a comparison of personal and occupational characteristics, disability, and prognosis among 12,195 workers from 18 countries Pain. 2016 May; 157(5):1028-36. . View in PubMed

Association of early life exposure to bisphenol A with obesity and cardiometabolic traits in childhood Environ Res. 2016 Apr; 146:379-87. . View in PubMed

Fish Intake in Pregnancy and Child Growth: A Pooled Analysis of 15 European and US Birth Cohorts JAMA Pediatr. 2016 Apr; 170(4):381-90. . View in PubMed

Exposure of Preschool-Age Greek Children (RHEA Cohort) to Bisphenol A, Parabens, Phthalates, and Organophosphates Environ Sci Technol. 2016 Jan 19; 50(2):932-41. . View in PubMed

Impact of prenatal exposure to cadmium on cognitive development at preschool age and the importance of selenium and iodine Eur J Epidemiol. 2016 11; 31(11):1123-1134. . View in PubMed

Common infections with polyomaviruses and herpesviruses and neuropsychological development at 4 years of age, the Rhea birth cohort in Crete, Greece J Child Psychol Psychiatry. 2016 11; 57(11):1268-1276. . View in PubMed

Is there an association between eating behaviour and attention-deficit/hyperactivity disorder symptoms in preschool children? J Child Psychol Psychiatry. 2016 06; 57(6):676-84.. View in PubMed

Cord blood leptin levels in relation to child growth trajectories Metabolism. 2016 06; 65(6):874-82. . View in PubMed

Dietary patterns in early childhood and child cognitive and psychomotor development: the Rhea mother-child cohort study in Crete Br J Nutr. 2016 04; 115(8):1431-7. . View in PubMed

Descriptive Epidemiology of Somatising Tendency: Findings from the CUPID Study PLoS One. 2016; 11(4):e0153748. . View in PubMed

ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle Clin Transl Allergy. 2016; 6:47. . View in PubMed

Erratum: "Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother-Child Study (NewGeneris)" Environ Health Perspect. 2016 Jan; 124(1):A12. . View in PubMed

Early life determinants of dietary patterns in preschool children: Rhea mother-child cohort, Crete, Greece Eur J Clin Nutr. 2016 Jan; 70(1):60-5. . View in PubMed

Fish Intake During Pregnancy and Offspring Adiposity-Reply JAMA Pediatr. 2016 08 01; 170(8):809-10. . View in PubMed

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation Allergy. 2015 Nov; 70(11):1372-92. . View in PubMed

Association of Prenatal Exposure to Persistent Organic Pollutants with Obesity and Cardiometabolic Traits in Early Childhood: The Rhea Mother-Child Cohort (Crete, Greece) Environ Health Perspect. 2015 Oct; 123(10):1015-21. . View in PubMed

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis. Allergy. 2015 Sep; 70(9):1062-78.. View in PubMed

Environmental, dietary, maternal, and fetal predictors of bulky DNA adducts in cord blood: a European mother-child study (NewGeneris) Environ Health Perspect. 2015 Apr; 123(4):374-80. . View in PubMed

Association of trimester-specific gestational weight gain with fetal growth, offspring obesity, and cardiometabolic traits in early childhoodAm J Obstet Gynecol. 2015 Apr; 212(4):502. e1-14. . View in PubMed

Breastfeeding duration and cognitive, language and motor development at 18 months of age: Rhea mother-child cohort in Crete, Greece J Epidemiol Community Health. 2015 Mar; 69(3):232-9. . View in PubMed

Effect of maternal n-3 long-chain polyunsaturated fatty acid supplementation during pregnancy and/or lactation on adiposity in childhood: a systematic review and meta-analysis of randomized controlled trials Eur J Clin Nutr. 2014 Dec; 68(12):1277-87. . View in PubMed

Caesarean deliveries in the Mother-Child (Rhea) cohort in Crete, Greece: almost as frequent as vaginal births and even more common in first-time mothers Hippokratia. 2014 Oct-Dec; 18(4):298-305. . View in PubMed

Air pollution during pregnancy and childhood cognitive and psychomotor development: six European birth cohorts Epidemiology. 2014 Sep; 25(5):636-47. . View in PubMed

Maternal diet, prenatal exposure to dioxin-like compounds and birth outcomes in a European prospective mother-child study (NewGeneris) Sci Total Environ. 2014 Jun 15; 484:121-8. . View in PubMed

Antenatal maternal mental health as determinant of postpartum depression in a population based mother-child cohort (Rhea Study) in Crete, Greece Soc Psychiatry Psychiatr Epidemiol. 2014 May; 49(5):711-21. . View in PubMed

In utero exposure to compounds with dioxin-like activity and birth outcomes Epidemiology. 2014 Mar; 25(2):215-24. . View in PubMed

Fish intake during pregnancy, fetal growth, and gestational length in 19 European birth cohort studies Am J Clin Nutr. 2014 Mar; 99(3):506-16. . View in PubMed

Exposure to brominated trihalomethanes in water during pregnancy and micronuclei frequency in maternal and cord blood lymphocytes Environ Health Perspect. 2014 Jan; 122(1):100-6. . View in PubMed

Increased frequency of micronuclei in mononucleated lymphocytes and cytome analysis in healthy newborns as an early warning biomarkers of possible future health risks Reprod Toxicol. 2013 Dec; 42:110-5. . View in PubMed

Ambient air pollution and low birthweight: a European cohort study (ESCAPE) Lancet Respir Med. 2013 Nov; 1(9):695-704. . View in PubMed

Bulky dna adducts in cord blood, maternal fruit-and-vegetable consumption, and birth weight in a European mother-child study (NewGeneris) Environ Health Perspect. 2013 Oct; 121(10):1200-6. . View in PubMed

Maternal diet, prenatal exposure to dioxins and other persistent organic pollutants and anogenital distance in children Sci Total Environ. 2013 Sep 01; 461-462:222-9. . View in PubMed

Maternal weight status, cord blood leptin and fetal growth: a prospective mother-child cohort study (Rhea study) Paediatr Perinat Epidemiol. 2013 Sep; 27(5):461-71. . View in PubMed

Antenatal and postnatal maternal mental health as determinants of infant neurodevelopment at 18 months of age in a mother-child cohort (Rhea Study) in Crete, Greece Soc Psychiatry Psychiatr Epidemiol. 2013 Aug; 48(8):1335-45. . View in PubMed

Disabling musculoskeletal pain in working populations: is it the job, the person, or the culture? Pain. 2013 Jun; 154(6):856-63.. View in PubMed

Maternal personality traits and risk of preterm birth and fetal growth restriction Eur Psychiatry. 2013 May; 28(4):213-8. . View in PubMed

Exposure to different sources of second-hand smoke during pregnancy and its effect on urinary cotinine and tobacco-specific nitrosamine (NNAL) concentrations Tob Control. 2013 May; 22(3):194-200. . View in PubMed

Maternal pre-pregnancy overweight and obesity, and child neuropsychological development: two Southern European birth cohort studies Int J Epidemiol. 2013 Apr; 42(2):506-17. . View in PubMed

Anogenital distances in newborns and children from Spain and Greece: predictors, tracking and reliability Paediatr Perinat Epidemiol. 2013 Jan; 27(1):89-99. . View in PubMed

In utero exposure to dioxins and dioxin-like compounds and anogenital distance in newborns and infants Environ Health Perspect. 2013 Jan; 121(1):125-30. . View in PubMed

Gender-specific reference intervals for cord blood leptin in Crete, Greece Eur J Pediatr. 2012 Oct; 171(10):1563-6. . View in PubMed

Effect of high doses of folic acid supplementation in early pregnancy on child neurodevelopment at 18 months of age: the mother-child cohort 'Rhea' study in Crete, Greece Public Health Nutr. 2012 Sep; 15(9):1728-36. . View in PubMed

Influence of fetal glutathione S-transferase copy number variants on adverse reproductive outcomes BJOG. 2012 Aug; 119(9):1141-6. . View in PubMed

Exposure to second-hand smoke and reproductive outcomes depending on maternal asthma Eur Respir J. 2012 Aug; 40(2):371-6. . View in PubMed

Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother-child study (NewGeneris) Environ Health Perspect. 2012 12; 120(12):1739-45. . View in PubMed

Epidemiological Differences Between Localized and Nonlocalized Low Back Pain Spine (Phila Pa 1976). 2017 May 15; 42(10):740-747. . View in PubMed

Dr Chatzi is a physician-environmental epidemiologist with expertise in birth cohort research. Her research focuses on the influence of nutrition and obesogenic chemical exposures during pregnancy and early childhood on long-term maternal and child health, especially obesity, asthma and cognitive development. She has published widely on the effects of early life exposure to endocrine disrupting chemicals on obesity and metabolic outcomes in children. In support of this work, she has led studies examining maternal and infant diet and their associations with the risk of adiposity and asthma in childhood. She is the principal investigator and co-leader of the “Rhea” pregnancy cohort in Greece and she has had significant leadership roles in major cohort studies studying environmental exposures early in life.
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