Proteomics Core Facility
The Proteomics Core Facility of the University of Southern California is located in Harlyne Norris Research Tower (NRT G510) at Keck School of Medicine. The Core provides high-sensitivity and high-resolution mass spectrometry for protein and peptide analysis as its primary technology. The Core is a university-wide resource and is supported by funds from the Keck School of Medicine and Center for Liver and Digestive Diseases. This state-of-the-art facility was established and is headed by Dr. Ebrahim Zandi, Associate Professor of Molecular Microbiology and Immunology and the Faculty Director of the Proteomics Core. Services include protein identification and protein quantitation from a wide variety of sample types from simple mixtures (gel spots and bands) to complex mixtures (protein complexes, cell lysates, and plasma).
The USC Proteomics Core uses mass spectrometry as the key technology for the qualitative and quantitative characterization of proteins. Our principal approach for the analysis of proteins is ‘shot-gun’ proteomics, where all proteins are proteolytically digested, producing signature peptides of the original proteins.
We educate and provide support for our collaborators to design and tailor proteomics experiments to obtain high quality data for publications and grant proposals. The Core also continually innovates on existing technologies.