Basic Science Research
International research leaders in clinical psychiatry, translational research, health services research and the neurosciences
Partnerships with a network of community agencies, health care leaders and regional academic institutions help us leverage science, innovation, and leadership – and to develop new ways to practice. Our research faculty engage in the “best questions” for achieving targeted outcomes and develop processes for quality and self-improvement for the practice of psychiatry.
Brain Imaging and Parkinson’s Disease
Utilizing brain imaging in rodent behavior models of pain, traumatic brain injury, Parkinson’s disease, fear, and exercise.
Cognitive Behavior and Electrophysiological Networks
Evaluating the role of electrophysiological networks involved in NMDA receptor hypofunction and utilizing deep brain stimulation to improve cognitive behavior in rodent models.
Developmental Signaling Networks
Determining how psychiatric disorder candidate risk factors are functionally integrated at the synapse and how mutations affect their function, not individually, but in developmental signaling network.
Utilizing data mining algorithms to screen hundreds of drugs for efficacy in datasets of nearly 1 million treated patients to identify those mostly likely to slow the progression of Alzheimer disease and to generate new leads for future clinical trials.
Molecular Genetics of Neurocognitive Function
Studying the biological and genetic basis of severe psychiatric illnesses across the lifespan.
Schizophrenia and Autism Spectrum Disorders
Studying animal models of circuitry and cellular function linked to psychosis. Leading studies of autoimmune causes of psychosis. Collaborating with neurosurgery to examine use of transcranial stimulation in treating OCD, depression, and schizophrenia.
Transitional Age Brain Development
Examining brain-based mechanisms and environmental effects on brain development in transitional age groups.