Clinical Research


Our diverse research programs have experienced unprecedented growth in recent years

Departmental research interests run a wide gamut including psychiatric genetics, clinical treatments and health services research. The department aims to advance research of the biomedical mental illness and adjustment by patients, families and others to medical and mental illness.

Genomic Psychiatry Cohort

Michele Pato, MD, co-created the Genomic Psychiatry Cohort, which includes more than 37,000 participants who have agreed to provide DNA samples for genomic, epidemiological and clinical studies.

Obsessive-Compulsive Disorder Genomics Study

Michele Pato, MD, and James A. Knowles MD, PhD, are expanding the Genomic Psychiatry Cohort by ascertaining and enrolling 5,000 patients suffering from Obsessive-Compulsive Disorder (OCD) and performing a genome-wide association study on 5,000 OCD patients and 5,000 already ascertained and genotyped OCD-free matched controls. The study offers a critical step to achieving the necessary statistical power for discovery. They will more than double the total number of available worldwide participants for the study and create the only large re-contactable cohort for OCD.