{"id":22,"date":"2024-01-31T16:16:13","date_gmt":"2024-01-31T16:16:13","guid":{"rendered":"https:\/\/keck.usc.edu\/statistical-genomics-center\/?page_id=22"},"modified":"2024-01-31T16:16:14","modified_gmt":"2024-01-31T16:16:14","slug":"project-3-statistical-methods-for-genome-characterization","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/statistical-genomics-center\/projects\/project-3-statistical-methods-for-genome-characterization\/","title":{"rendered":"Project 3:\u00a0Statistical Methods for Genome Characterization"},"content":{"rendered":"\n\n\n\n\n  \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/\"  aria-label=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/\">Center for Statistical Genomics<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n      <h1>Project 3:\u00a0Statistical Methods for Genome Characterization<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/github.com\/USCbiostats\/software-dev\/blob\/master\/happy_scientist\/README.md\"\n  target=\"_blank\"  >\n        Happy Scientist Seminars\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                                  In This Section\n                                <svg class=\"menu\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\"\n                  y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#000\" d=\"M4,23h3v3H4V23z M4,16h3v3H4V16z M10,23\n                  h21v3H10V23z M10,16h21v3H10V16z M10,9h21v3H10V9z M4,9h3v3H4V9z\"\/>\n                <\/svg>\n\n                <svg class=\"close\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\"\n                  viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <polygon fill=\"#000\" fill-rule=\"evenodd\" clip-rule=\"evenodd\" points=\"26,10.4 24.6,9 17.5,16.1 10.4,9 9,10.4 16.1,17.5\n                  9,24.6 10.4,26 17.5,18.9 24.6,26 26,24.6 18.9,17.5 \"\/>\n                <\/svg>\n              <\/button>\n\n              <nav\n  class=\"mc--menu mc--\"\n  >\n  <ul class=\"m--menu m--\">\n    \n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-home menu-item-15\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/\" >Center for Statistical Genomics<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-16\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/faculty\/\" >Faculty<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-25 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/projects\/\" >Projects<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Projects\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-28\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/projects\/project-1-integration-of-omic-data-to-estimate-mediation-or-latent-structures\/\" >Project 1:\u00a0Integration of Omic Data to Estimate Mediation or Latent Structures<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-27\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/projects\/project-2-integration-of-omic-data-in-the-analysis-of-gene-x-environment-interaction\/\" >Project 2:\u00a0Integration of Omic Data in the Analysis of Gene \u00d7 Environment Interaction<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-26\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/projects\/project-3-statistical-methods-for-genome-characterization\/\" >Project 3:\u00a0Statistical Methods for Genome Characterization<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-custom menu-item-object-custom menu-item-30\">\n      <a href=\"https:\/\/github.com\/USCbiostats\" >Software<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-17\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/publications\/\" >Publications<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-custom menu-item-object-custom menu-item-31\">\n      <a href=\"https:\/\/github.com\/USCbiostats\/software-dev\/blob\/master\/happy_scientist\/README.md\" >Resources and Events<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-custom menu-item-object-custom menu-item-43\">\n      <a href=\"https:\/\/keck.usc.edu\/news\/tag\/center-for-statistical-genomics\/\" >News<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-33\">\n      <a href=\"https:\/\/keck.usc.edu\/statistical-genomics-center\/contact\/\" >Contact<\/a>\n  \n  \n<\/li>\n\n    \n      <\/ul><!-- m--menu -->\n<\/nav>\n\n            <\/div>\n                  <\/div>\n        <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <div id=\"overview\" class=\"et_pb_module et_pb_text et_pb_text_7 et_pb_text_align_left et_pb_bg_layout_light\">\n<div class=\"et_pb_text_inner\">\n<h2 style=\"text-align: center;\">Overview<\/h2>\n<\/div>\n<\/div>\n<div class=\"et_pb_module et_pb_text et_pb_text_8 et_pb_text_align_left et_pb_bg_layout_light\">\n<div class=\"et_pb_text_inner\">\n<p>Understanding the role that genes play in life is a key issue in biomedical sciences, yet the overwhelming majority of sequences in public databases remain uncharacterized. Functional annotation is important for a variety of downstream analyses of genetic data, yet experimental characterization of function remains costly and slow. This project therefore proposes three Aims focused on improving our understanding of functional genomics, thereby allowing better translation of data to knowledge impacting human health.<\/p>\n<\/div>\n<\/div>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n  \n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--contact-details \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--contact-details\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n\n          <div class=\"header-container\">\n\n                      \n<div class=\"f--field f--section-title\">\n\n    \n  <h2>\n          INVESTIGATORS\n      <\/h2>\n\n\n<\/div>\n        \n        \n      <\/div>\n    \n    \n      <div class=\"contacts-container\">\n\n        \n                      <div class=\"contact-card\">\n\n                              <h3>Paul Marjoram, PhD<\/h3>\n              \n                                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p>Professor of Research, Population and Public Health Sciences<\/p>\n\n\n\n<\/div>\n              \n              \n                              <div class=\"f--email\">\n                  <a href=\"mailto:pmarjora@usc.edu\">pmarjora@usc.edu<\/a>\n                <\/div>\n              \n            <\/div>\n                    \n      <\/div>\n\n    \n    \n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":18,"featured_media":0,"parent":19,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-22","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - 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