John C. Lipham, MD

John C. Lipham, M.D. is Chief of the Division of Upper GI and General Surgery and Associate Professor of Surgery at the Keck School of Medicine of USC. Dr. Lipham also served as the Foregut Cancer Program Director and Chief of USC Affiliated Academic Programs at Hoag. He was instrumental in establishing the Hoag-USC Surgical Center for Digestive Diseases. He focuses on benign and malignant diseases of the esophagus and stomach. His clinical interests include the diagnosis and treatment of GERD, hiatal hernias, Barrett’s esophagus, esophageal motility disorders, achalasia, malignant diseases of the esophagus and stomach, and gastroparesis. His current research interests include developing minimally invasive methods of diagnosing and treating gastroesophageal reflux disease, Barrett’s, esophageal cancer and gastric cancer.

• Short term safety of magnetic sphincter augmentation vs minimally invasive fundoplication: an ACS-NSQIP analysis Surg Endosc. 2024 Apr; 38(4):1944-1949. . View in PubMed
• Short-term Outcomes of Different Techniques for Gastric Ischemic Preconditioning Before Esophagectomy: A Network Meta-analysis Ann Surg. 2024 Mar 01; 279(3):410-418. . View in PubMed
• Trends and outcomes of intraoperative esophagogastroduodenoscopy during laparoscopic Heller myotomy: a National Surgical Quality Improvement Program analysis J Gastrointest Surg. 2024 Mar; 28(3):282-284. . View in PubMed
• Is Endoscopic Surveillance Needed After Laparoscopic Sleeve Gastrectomy? Curr Obes Rep. 2024 Jan 03.. View in PubMed
• Antireflux Surgery Does Not Prevent Cancer in Barrett’s Esophagus Gastroenterology. 2024 Jan; 166(1):21-23. . View in PubMed
• Tumor differentiation impacts response to neoadjuvant therapy and survival in patients with esophageal adenocarcinoma J Thorac Cardiovasc Surg. 2023 Oct 01. . View in PubMed
• Magnetic sphincter augmentation: laparoscopic or robotic approach? Dis Esophagus. 2023 Jun 15; 36(Supplement_1).. View in PubMed
• Use of magnetic sphincter augmentation as an adjunct procedure in paraesophageal hernia repair Dis Esophagus. 2023 Jun 15; 36(Supplement_1). . View in PubMed
• Lower Rates of Unplanned Conversion to Open in Robotic Approach to Esophagectomy for Cancer Am Surg. 2023 Jun; 89(6):2583-2594. . View in PubMed
• The Impact of Ineffective Esophageal Motility on Patients Undergoing Magnetic Sphincter Augmentation Ann Surg. 2023 04 01; 277(4):e793-e800. . View in PubMed
• Impact of Robotic Approach on Post-Anastomotic Leaks After Esophagectomy for Esophageal Cancer Am Surg. 2022 Oct; 88(10):2499-2507. . View in PubMed
• Gastric electric stimulator versus gastrectomy for the treatment of medically refractory gastroparesis Surg Endosc. 2022 Oct; 36(10):7561-7568. . View in PubMed
• Loosening the belt on magnetic sphincter augmentation indications: does body mass index matter? Surg Endosc. 2022 07; 36(7):4878-4884.. View in PubMed
• Sleeve Gastrectomy as a Novel Procedure for Gastroparesis Am Surg. 2021 Aug; 87(8):1287-1291. . View in PubMed
• Safety and efficacy of robotic-assisted groin hernia repair J Robot Surg. 2021 Aug; 15(4):547-552. . View in PubMed
• Regression of Barrett’s esophagus after magnetic sphincter augmentation: intermediate-term results Surg Endosc. 2021 10; 35(10):5804-5809. . View in PubMed
• Magnetic sphincter augmentation with hiatal hernia repair: long term outcomes Surg Endosc. 2021 10; 35(10):5607-5612. . View in PubMed
• Less is more: cruroplasty alone is sufficient for revisional hiatal hernia surgery Surg Endosc. 2021 08; 35(8):4661-4666. . View in PubMed
• Comparative efficacy of first-line therapeutic interventions for achalasia: a systematic review and network meta-analysis Surg Endosc. 2021 08; 35(8):4305-4314. . View in PubMed
• Safety and efficacy of magnetic sphincter augmentation dilation Surg Endosc. 2021 07; 35(7):3861-3864. . View in PubMed
• Letter to the editor by the American Foregut Society Bariatric Committee on Combined Magnetic Sphincter Augmentation and Bariatric Surgery Surg Obes Relat Dis. 2021 05; 17(5):1034-1035. . View in PubMed
• Response to the Comment on “Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study” Ann Surg. 2021 12 01; 274(6):e666-e667. . View in PubMed
• Understanding the GERD Barrier J Clin Gastroenterol. 2021 07 01; 55(6):459-468. . View in PubMed
• Postoperative Dysphagia Following Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease Surg Laparosc Endosc Percutan Tech. 2020 Aug; 30(4):322-326. . View in PubMed
• Clinical outcome after laparoscopic Nissen fundoplication in patients with GERD and PPI refractory heartburn Dis Esophagus. 2020 Apr 15; 33(4). . View in PubMed
• Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease Gastrointest Endosc Clin N Am. 2020 Apr; 30(2):325-342. . View in PubMed
• Magnetic sphincter augmentation versus fundoplication for gastroesophageal reflux disease: pros and cons Curr Opin Gastroenterol. 2020 07; 36(4):323-328. . View in PubMed
• Surgical and endoscopic management options for patients with GERD based on proton pump inhibitor symptom response: recommendations from an expert US. panel. Gastrointest Endosc. 2020 07; 92(1):78-87. e2. . View in PubMed
• Magnetic Sphincter Augmentation Superior to Proton Pump Inhibitors for Regurgitation in a 1-Year Randomized TrialClin Gastroenterol Hepatol. 2020 07; 18(8):1736-1743. e2. . View in PubMed
• Comment on: Systematic review of the introduction and evaluation of magnetic augmentation of the lower oesophageal sphincter for gastro-oesophageal reflux disease Br J Surg. 2020 06; 107(7):e209. . View in PubMed
• A budget impact analysis of a magnetic sphincter augmentation device for the treatment of medication-refractory mechanical gastroesophageal reflux disease: a United States payer perspective Surg Endosc. 2020 04; 34(4):1561-1572. . View in PubMed
• Management of lateral abdominal hernias Hernia. 2020 04; 24(2):353-358. . View in PubMed
• Volumetric laser endomicroscopy and its application to Barrett’s esophagus: results from a 1,000 patient registry Dis Esophagus. 2019 Nov 13; 32(9). . View in PubMed
• Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study Ann Surg. 2019 08; 270(2):302-308. . View in PubMed
• Clinical Significance of Esophageal Outflow Resistance Imposed by a Nissen Fundoplication J Am Coll Surg. 2019 08; 229(2):210-216. . View in PubMed
• Removing the magnetic sphincter augmentation device: operative management and outcomes Surg Endosc. 2019 08; 33(8):2663-2669. . View in PubMed
• Routine esophageal manometry is not useful in patients with normal videoesophagram Surg Endosc. 2019 05; 33(5):1650-1653. . View in PubMed
• Minimal versus obligatory dissection of the diaphragmatic hiatus during magnetic sphincter augmentation surgery Surg Endosc. 2019 03; 33(3):782-788. . View in PubMed
• Regression of intestinal metaplasia following magnetic sphincter augmentation device placement Surg Endosc. 2019 02; 33(2):576-579. . View in PubMed
• Laparoscopic magnetic sphincter augmentation versus double-dose proton pump inhibitors for management of moderate-to-severe regurgitation in GERD: a randomized controlled trialGastrointest Endosc. 2019 01; 89(1):14-22. e1. . View in PubMed
• Extraluminal Approaches to Gastroesophageal Reflux Disease Thorac Surg Clin. 2018 Nov; 28(4):521-526. . View in PubMed
• Videoesophagography versus Endoscopy for Prediction of Intraoperative Hiatal Hernia Size Am Surg. 2018 Mar 01; 84(3):387-391. . View in PubMed
• Worldwide Experience with Erosion of the Magnetic Sphincter Augmentation Device J Gastrointest Surg. 2018 08; 22(8):1442-1447. . View in PubMed
• Hiatal hernia recurrence following magnetic sphincter augmentation and posterior cruroplasty: intermediate-term outcomes Surg Endosc. 2018 07; 32(7):3374-3379. . View in PubMed
• Esophageal adenocarcinoma stage III: Survival based on pathological response to neoadjuvant treatment Surg Oncol. 2017 Dec; 26(4):522-526. . View in PubMed
• Lower Esophageal Sphincter Augmentation for Gastroesophageal Reflux Disease: The Safety of a Modern Implant J Laparoendosc Adv Surg Tech A. 2017 Jun; 27(6):586-591. . View in PubMed
• Gastric cancer in the young: An advanced disease with poor prognostic features J Surg Oncol. 2017 Mar; 115(4):371-375. . View in PubMed
• Efficacy of magnetic sphincter augmentation in patients with large hiatal hernias Surg Endosc. 2017 05; 31(5):2096-2102. . View in PubMed
• Post-Nissen Dysphagia and Bloating Syndrome: Outcomes After Conversion to Toupet Fundoplication J Gastrointest Surg. 2017 03; 21(3):441-445. . View in PubMed
• A Durable Laparoscopic Technique for the Repair of Large Paraesophageal Hernias Am Surg. 2016 Oct; 82(10):911-915. . View in PubMed
• Long-term Outcomes of Patients Receiving a Magnetic Sphincter Augmentation Device for Gastroesophageal Reflux Clin Gastroenterol Hepatol. 2016 May; 14(5):671-7. . View in PubMed
• Intraoperative assessment of the effects of laparoscopic sleeve gastrectomy on the distensibility of the lower esophageal sphincter using impedance planimetry Surg Endosc. 2016 11; 30(11):4904-4909. . View in PubMed
• Charges, outcomes, and complications: a comparison of magnetic sphincter augmentation versus laparoscopic Nissen fundoplication for the treatment of GERD Surg Endosc. 2016 08; 30(8):3225-30. . View in PubMed
• Multi-institutional outcomes using magnetic sphincter augmentation versus Nissen fundoplication for chronic gastroesophageal reflux disease Surg Endosc. 2016 08; 30(8):3289-96. . View in PubMed
• Magnetic Sphincter Augmentation for Gastroesophageal Reflux at 5 Years: Final Results of a Pilot Study Show Long-Term Acid Reduction and Symptom Improvement J Laparoendosc Adv Surg Tech A. 2015 Oct; 25(10):787-92. . View in PubMed
• Three-dimensional Laparoscopy: Does Improved Visualization Decrease the Learning Curve Among Trainees in Advanced Procedures? Surg Laparosc Endosc Percutan Tech. 2015 Aug; 25(4):321-3.. View in PubMed
• Intraoperative Assessment of Perfusion of the Gastric Graft and Correlation With Anastomotic Leaks After Esophagectomy Ann Surg. 2015 Jul; 262(1):74-8. . View in PubMed
• Laparoscopic Magnetic Sphincter Augmentation vs Laparoscopic Nissen Fundoplication: A Matched-Pair Analysis of 100 Patients J Am Coll Surg. 2015 Jul; 221(1):123-8. . View in PubMed
• Safety analysis of first 1000 patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease Dis Esophagus. 2015 May-Jun; 28(4):305-11. . View in PubMed
• The Durability of Endoscopic Therapy for Treatment of Barrett’s Metaplasia, Dysplasia, and Mucosal Cancer After Nissen Fundoplication J Gastrointest Surg. 2015 May; 19(5):799-805. . View in PubMed
• Percutaneous cholecystostomy versus laparoscopic cholecystectomy in patients with acute cholecystitis and failed conservative management: a matched-pair analysis Surg Laparosc Endosc Percutan Tech. 2014 Dec; 24(6):523-7. . View in PubMed
• Magnetic sphincter augmentation with the LINX device for gastroesophageal reflux disease after US. Food and Drug Administration approval. Am Surg. 2014 Oct; 80(10):1034-8. . View in PubMed
• Esophagectomy for failed endoscopic therapy in patients with high-grade dysplasia or intramucosal carcinoma Dis Esophagus. 2014 May-Jun; 27(4):362-7. . View in PubMed
• Outcomes following laparoscopic transhiatal esophagectomy for esophageal cancer Surg Endosc. 2014 Feb; 28(2):492-9. . View in PubMed
• Biologic versus nonbiologic mesh in ventral hernia repair: a systematic review and meta-analysis World J Surg. 2014 Jan; 38(1):40-50. . View in PubMed
• LINX(®) Reflux Management System in chronic gastroesophageal reflux: a novel effective technology for restoring the natural barrier to reflux Therap Adv Gastroenterol. 2013 Jul; 6(4):261-8. . View in PubMed
• Adenocarcinoma of the esophagus in the young J Gastrointest Surg. 2013 Jun; 17(6):1032-5. . View in PubMed
• Single-access laparoscopic cholecystectomy versus classic laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized controlled trials Surg Laparosc Endosc Percutan Tech. 2013 Jun; 23(3):235-43. . View in PubMed
• Esophageal sphincter device for gastroesophageal reflux disease N Engl J Med. 2013 Feb 21; 368(8):719-27. . View in PubMed
• Minimally invasive surgical approach for the treatment of gastroparesis Surg Endosc. 2013 Jan; 27(1):61-6. . View in PubMed
• The LINX® reflux management system: confirmed safety and efficacy now at 4 years Surg Endosc. 2012 Oct; 26(10):2944-9. . View in PubMed
• Intraluminal pH and goblet cell density in Barrett’s esophagus J Gastrointest Surg. 2012 Mar; 16(3):469-74. . View in PubMed
• Circular stapled pyloroplasty: a fast and effective technique for pyloric disruption during esophagectomy with gastric pull-up Dis Esophagus. 2011 Aug; 24(6):423-9. . View in PubMed
• Day-to-day discrepancy in Bravo pH monitoring is related to the degree of deterioration of the lower esophageal sphincter and severity of reflux disease Surg Endosc. 2011 Jul; 25(7):2219-23. . View in PubMed
• Thoraco-abdominal pressure gradients during the phases of respiration contribute to gastroesophageal reflux disease Dig Dis Sci. 2011 Jun; 56(6):1718-22. . View in PubMed
• Laparoscopic versus open repair of paraesophageal hernia: the second decade J Am Coll Surg. 2011 May; 212(5):813-20. . View in PubMed
• The prevalence of lymph node metastases in patients with T1 esophageal adenocarcinoma a retrospective review of esophagectomy specimens Ann Surg. 2011 Feb; 253(2):271-8. . View in PubMed
• Endoscopic resection and ablation versus esophagectomy for high-grade dysplasia and intramucosal adenocarcinoma J Thorac Cardiovasc Surg. 2011 Jan; 141(1):39-47. . View in PubMed
• Loss of alkalization in proximal esophagus: a new diagnostic paradigm for patients with laryngopharyngeal reflux J Gastrointest Surg. 2010 Nov; 14(11):1653-9. . View in PubMed
• Laparoscopic sphincter augmentation device eliminates reflux symptoms and normalizes esophageal acid exposure: one- and 2-year results of a feasibility trial Ann Surg. 2010 Nov; 252(5):857-62. . View in PubMed
• Esophagectomy for cancer in octogenarians Dis Esophagus. 2010 Nov; 23(8):666-9. . View in PubMed
• Long-term follow-up after anti-reflux surgery in patients with Barrett’s esophagus J Gastrointest Surg. 2010 Oct; 14(10):1483-91. . View in PubMed
• Detection of gastric conduit ischemia or anastomotic breakdown after cervical esophagogastrostomy: the use of computed tomography scan versus early endoscopy Surg Endosc. 2010 Aug; 24(8):1948-51. . View in PubMed
• The impact of gastric distension on the lower esophageal sphincter and its exposure to acid gastric juice Ann Surg. 2010 Jul; 252(1):57-62. . View in PubMed
• Progressive mucosal injury in patients with gastroesophageal reflux disease and increasing peripheral blood eosinophil counts Arch Surg. 2010 Apr; 145(4):363-6. . View in PubMed
• Recurrence after esophagectomy for adenocarcinoma: defining optimal follow-up intervals and testing J Am Coll Surg. 2010 Apr; 210(4):428-35. . View in PubMed
• Esophageal intraepithelial eosinophils in dysphagic patients with gastroesophageal reflux disease Dig Dis Sci. 2010 Apr; 55(4):967-72. . View in PubMed
• A simplified technique for intrathoracic stomach repair: laparoscopic fundoplication with Vicryl mesh and BioGlue crural reinforcement Surg Endosc. 2010 Mar; 24(3):675-9. . View in PubMed
• Proximal esophageal pH monitoring: improved definition of normal values and determination of a composite pH score J Am Coll Surg. 2010 Mar; 210(3):345-50. . View in PubMed
• The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter J Gastrointest Surg. 2009 Dec; 13(12):2113-20. . View in PubMed
• Measurement of gastric pH in ambulatory esophageal pH monitoring Surg Endosc. 2009 Sep; 23(9):1968-73. . View in PubMed
• Clinical characteristics, biologic behavior, and survival after esophagectomy are similar for adenocarcinoma of the gastroesophageal junction and the distal esophagus J Thorac Cardiovasc Surg. 2009 Sep; 138(3):594-602; discussion 601-2. . View in PubMed
• Obesity and gastroesophageal reflux: quantifying the association between body mass index, esophageal acid exposure, and lower esophageal sphincter status in a large series of patients with reflux symptoms J Gastrointest Surg. 2009 Aug; 13(8):1440-7. . View in PubMed
• A new technique for measurement of pharyngeal pH: normal values and discriminating pH threshold J Gastrointest Surg. 2009 Aug; 13(8):1422-9. . View in PubMed
• Delayed esophagogastrostomy: a safe strategy for management of patients with ischemic gastric conduit at time of esophagectomy J Am Coll Surg. 2009 Jun; 208(6):1030-4. . View in PubMed
• Laparoscopic Nissen fundoplication assessment: task analysis as a model for the development of a procedural checklist Surg Endosc. 2009 Jun; 23(6):1227-32. . View in PubMed
• Survival in lymph node negative adenocarcinoma of the esophagus after R0 resection with and without neoadjuvant therapy: evidence for downstaging of N status J Am Coll Surg. 2009 Apr; 208(4):553-6. . View in PubMed
• Esophageal pH exposure and epithelial cell differentiation Dis Esophagus. 2009; 22(7):596-9. . View in PubMed
• Bravo catheter-free pH monitoring: normal values, concordance, optimal diagnostic thresholds, and accuracy Clin Gastroenterol Hepatol. 2009 Jan; 7(1):60-7. . View in PubMed
• An improved method of assessing esophageal emptying using the timed barium study following surgical myotomy for achalasia J Gastrointest Surg. 2009 Jan; 13(1):14-8. . View in PubMed
• Recurrence of intramucosal esophageal adenocarcinoma arising in a former esophagostomy site: a unique case report Dis Esophagus. 2009; 22(6):E17-20. . View in PubMed
• Magnetic augmentation of the lower esophageal sphincter: results of a feasibility clinical trial J Gastrointest Surg. 2008 Dec; 12(12):2133-40. . View in PubMed
• Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer J Am Coll Surg. 2008 Jul; 207(1):30-5. . View in PubMed
• En bloc esophagectomy reduces local recurrence and improves survival compared with transhiatal resection after neoadjuvant therapy for esophageal adenocarcinoma J Thorac Cardiovasc Surg. 2008 Jun; 135(6):1228-36. . View in PubMed
• High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adults Am J Gastroenterol. 2008 Feb; 103(2):435-42. . View in PubMed
• Plasma DNA: a molecular marker of surgical insult and postoperative recovery in esophageal cancer Eur Surg Res. 2008; 40(3):273-8. . View in PubMed
• Vagal-sparing esophagectomy: the ideal operation for intramucosal adenocarcinoma and barrett with high-grade dysplasia Ann Surg. 2007 Oct; 246(4):665-71; discussion 671-4. . View in PubMed
• Reduction of interleukin 8 gene expression in reflux esophagitis and Barrett’s esophagus with antireflux surgery Arch Surg. 2007 Jun; 142(6):554-9; discussion 559-60. . View in PubMed
• Plasma DNA as a molecular marker for completeness of resection and recurrent disease in patients with esophageal cancer Arch Surg. 2007 Jun; 142(6):533-8; discussion 538-9. . View in PubMed
• Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagus J Am Coll Surg. 2006 Aug; 203(2):152-61. . View in PubMed
• The impact of reflux composition on mucosal injury and esophageal function J Gastrointest Surg. 2006 Jun; 10(6):787-96; discussion 796-7. . View in PubMed
• Bravo capsule induction of esophageal hypercontractility and chest pain Surg Endosc. 2006 May; 20(5):783-6. . View in PubMed
• Predictive factors of coexisting cancer in Barrett’s high-grade dysplasia Surg Endosc. 2006 Mar; 20(3):439-43. . View in PubMed
• Preoperative diagnosis of lymph node metastasis: a dream? Gastric Cancer. 2006; 9(2):70-1.. View in PubMed
• Gastric electrical stimulation: an alternative surgical therapy for patients with gastroparesis Arch Surg. 2005 Sep; 140(9):841-6; discussion 847-8. . View in PubMed
• The safety and usefulness of endoscopy for evaluation of the graft and anastomosis early after esophagectomy and reconstruction Surg Endosc. 2005 Aug; 19(8):1093-102. . View in PubMed
• Shank vessel injuries Surg Clin North Am. 2002 Feb; 82(1):91-104xx. . View in PubMed
• Rectal perforation in unstable pelvic fractures: the use of flexible sigmoidoscopy Injury. 2001 Jan; 32(1):67-8. . View in PubMed

• Gill, Inderbir
• Soffer, Edy
• Martin, Matthew
• Samakar, Kamran
• Desai, Mihir
• Oh, Daniel
• Shaker, Anisa
• Wu-Williams, Anna
• Matsuo, Koji
• Demetriades, Demetrios
• Lenz, Heinz-Josef
• Houghton, Caitlin
• Aron, Monish