{"id":15,"date":"2023-08-24T01:22:07","date_gmt":"2023-08-24T01:22:07","guid":{"rendered":"https:\/\/keck.usc.edu\/surgery\/?page_id=15"},"modified":"2024-07-27T00:06:27","modified_gmt":"2024-07-27T00:06:27","slug":"research","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/surgery\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n\n\n\n\n  \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/surgery\/\"  aria-label=\"Read more about Department of Surgery\">Department of Surgery<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n  <h1>Research<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/www.keckmedicine.org\/services\/surgery\/\"\n  target=\"_blank\"  aria-label=\"Read&#x20;more&#x20;about&#x20;Are&#x20;you&#x20;a&#x20;patient&#x3F;\">\n        Are you a patient?\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                                  In This Section\n                                <svg class=\"menu\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\"\n                  y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#000\" d=\"M4,23h3v3H4V23z M4,16h3v3H4V16z M10,23\n                  h21v3H10V23z M10,16h21v3H10V16z M10,9h21v3H10V9z M4,9h3v3H4V9z\"\/>\n                <\/svg>\n\n                <svg class=\"close\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\"\n                  viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <polygon fill=\"#000\" fill-rule=\"evenodd\" clip-rule=\"evenodd\" points=\"26,10.4 24.6,9 17.5,16.1 10.4,9 9,10.4 16.1,17.5\n                  9,24.6 10.4,26 17.5,18.9 24.6,26 26,24.6 18.9,17.5 \"\/>\n                <\/svg>\n              <\/button>\n\n              <nav\n  class=\"mc--menu mc--\"\n  >\n  <ul class=\"m--menu m--\">\n    \n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-home menu-item-6 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/\" >Surgery<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Surgery\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-587\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/inclusive-excellence\/\" >Inclusive Excellence<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-24\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/divisions\/\" >Divisions<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-21 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/research\/\" >Research<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Research\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-452\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/innovation-hub\/\" >Innovation Hub<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-22 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/\" >Training &amp; Education<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Training &amp; Education\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-54 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/\" >Residencies<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Residencies\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-107\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/resident-education\/\" >Resident Education<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-103\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/general-surgery-residency-program\/\" >General Surgery<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-119\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/colon-and-rectal-surgery-residency-program\/\" >Colon and Rectal Surgery Residency Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-118\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/independent-cardiothoracic-residency-program\/\" >Independent Cardiothoracic Residency Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-117\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/integrated-cardiothoracic-residency-program\/\" >Integrated Cardiothoracic Residency Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-552\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/independent-vascular-surgery-training-program\/\" >Independent Vascular Surgery Training Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-89\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/integrated-independent-vascular-surgery-training-program\/\" >Integrated Vascular Surgery Training Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-116\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/plastics-independent-residency-program\/\" >Plastics Independent Residency Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-115\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/plastics-integrated-residency-program\/\" >Plastics Integrated Residency Program<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n                      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-52 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/\" >Fellowships<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Fellowships\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-custom menu-item-object-custom menu-item-73\">\n      <a href=\"https:\/\/sites.usc.edu\/transplantfellowship\/\" target=\"_blank\">Abdominal Organ Transplant Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-83\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/advanced-gi-mis-fellowship-program\/\" >Advanced GI MIS Fellowship Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-84\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/breast-fellowship-program\/\" >Breast Surgical Oncology Fellowship Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-85\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/burn-fellowship-program\/\" >Burn Fellowship Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-86\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/congenital-cardiac-fellowship-program\/\" >Congenital Cardiac Fellowship Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-87\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/craniofacial-fellowship-program\/\" >Craniofacial Fellowship Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-88\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/hepato-pancreato-biliary-fellowship\/\" >Hepato-Pancreato-Biliary Fellowship<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-90\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/microsurgery-fellowship-program\/\" >Reconstructive Microsurgery Fellowship<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-91\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/fellowships\/surgical-critical-care-and-aast-fellowship\/\" >Surgical Critical Care and AAST Fellowship<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n                      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-245 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/general-surgery-residency-program\/\" >General Surgery Residency Program<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for General Surgery Residency Program\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-273\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/general-surgery-residency-program\/sub-internship-scholarship-award\/\" >Sub-Internship Scholarship Award<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-545\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/residencies\/general-surgery-residency-program\/culture-and-engagement\/\" >Culture and Engagement<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-53\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/medical-students\/\" >Medical Student Education<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-55\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/surgical-skills-simulation\/\" >Surgical Skills Simulation<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-61\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/physician-scientist-training-program\/\" >Physician-Scientist Training Program<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-60\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/training-education\/professional-development\/\" >Professional Development<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-23\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/patient-care\/\" >Patient Care<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-32\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/faculty\/\" >Faculty<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-25\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/support\/\" >Support<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-26\">\n      <a href=\"https:\/\/keck.usc.edu\/surgery\/contact\/\" >Contact<\/a>\n  \n  \n<\/li>\n\n    \n      <\/ul><!-- m--menu -->\n<\/nav>\n\n            <\/div>\n                  <\/div>\n        <\/div>\n\n\n  <\/div><\/div>\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--spacer \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--spacer\"\n    \n      >\n\n    \n\n  <\/div><\/div>\n\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--featured-block image-left white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          About Our Research Programs\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p>The Department of Surgery receives more than $1 million each year in extramural grants, which supports the department\u2019s long tradition of involvement in both basic and clinical research. A number of research studies are conducted in collaboration with other departments of the Keck School of Medicine, including the Department of Medicine and its divisions of gastrointestinal and liver diseases, infectious diseases and oncology.<\/p>\n\n\n\n<\/div>\n      \n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/surgery\/wp-content\/uploads\/sites\/45\/2023\/11\/2022109_USC_Health_Campaign_August_0024-768x768.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/surgery\/wp-content\/uploads\/sites\/45\/2023\/11\/2022109_USC_Health_Campaign_August_0024-1280x1280.jpg 1280w,https:\/\/keck.usc.edu\/surgery\/wp-content\/uploads\/sites\/45\/2023\/11\/2022109_USC_Health_Campaign_August_0024-768x768.jpg 768w\"          data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Craig Baker, MD, and Robert Sachs, PA-C, discuss images on a computer monitor\"\n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Cardiovascular Research Program is a joint partnership between the Research Institute and the Heart Institute. The goal of the Cardiovascular Research Program is to support and advance the pediatric and adult cardiac and vascular programs through basic and applied research activities. The basic science research activities take place in the laboratories on the fourth floor of The Saban Research Institute. The clinical research is carried out at Children\u2019s Hospital Los Angeles and in the laboratories at the USC Health Science Campus (HSC).<\/p>\n<p>Residents have the option to spend one year (or more in selected circumstances) to conduct basic science and\/or clinical research in any surgical specialty. Most residents elect to spend dedicated time outside of the residency to participate in full-time research, typically following the PGY-3 year. This dedicated research time is encouraged, but it is not mandatory. The type of research, location and funding is left to the discretion of the resident. However, there are opportunities to obtain internal funding from the department to facilitate this process. Additionally, there are ample opportunities to participate in clinical or translational research while engaged in the clinical rotations of the residency. Residents are encouraged to submit their research to meetings and will receive the necessary support to present their work. Previous residents have used this time to obtain advanced degrees such as an MBA or even a PhD. Other residents have pursued a critical care fellowship. The research period can be tailored to the specific professional needs of the individual.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--spacer \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--spacer\"\n    \n      >\n\n    \n\n  <\/div><\/div>\n\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--featured-block white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          <a name=\"Clinical\">Clinical Research<\/a>\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p><strong>The Department of Surgery is involved in various clinical research, translational research and clinical trials.<\/strong><\/p>\n<p>The Department of Surgery has a dedicated Surgical Research Unit for the implementation and conduct of clinical research. The SRU consists of a Director and Associate Director, three managers, two regulatory specialists, a nurse research coordinator, and research coordinators. This group is supported by a Financial Manager and Statistics resources and works closely with Pharmacists and Laboratory Personnel that are integral to the conduct of the research. The SRU maintains a Fluid and Tissue Biorepository that includes samples from surgical procedures in all of the surgical specialties and makes these available to researchers with approved basic science research projects.<br \/>\nThe SRU manages between 50 and 70 ongoing funded clinical studies, including the following:<\/p>\n\n\n\n<\/div>\n      \n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/surgery\/wp-content\/uploads\/sites\/45\/2024\/07\/Emamaullee-Tub-768x768.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/surgery\/wp-content\/uploads\/sites\/45\/2024\/07\/Emamaullee-Tub-1280x1280.jpg 1280w,https:\/\/keck.usc.edu\/surgery\/wp-content\/uploads\/sites\/45\/2024\/07\/Emamaullee-Tub-768x768.jpg 768w\"          data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Dr. Juliet Emamaullee stands by the Norton Herrick biorepository, a subzero storage system for tissue samples.\"\n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n                            \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--stacking-cards \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--stacking-cards\"\n    \n      >\n\n    \n  <div class=\"outer-wrapper\">\n    <div class=\"inner-wrapper\">\n      \n                <div class=\"cards-container\">\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Cardiothoracic Surgery\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Heart Valves \u2013 both for minimally invasive and open surgeries<br \/>\nThoracic Aortic Stents<br \/>\nAtrial Fibrillation<br \/>\nMonitoring devices<br \/>\nCardiac support<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Colorectal Surgery\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Bowel function recovery<br \/>\nAnastomosis protection<br \/>\nBiomarkers of colon cancer<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Gastrointestinal Surgery\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Management of GERD<br \/>\nControl of diabetes type 2<br \/>\nDevices to control reflux<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Hepatobiliary Surgery and Abdominal Organ Transplantation\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>New immunosuppression agents and strategies<br \/>\nBiomarkers of rejection<br \/>\nAlcoholic liver disease<br \/>\nHepatic regeneration<br \/>\nHemostatic agents<br \/>\nHighly sensitized patients<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Intensive Care Unit\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Respiratory infections<br \/>\nCOVID -19<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Vascular Surgery\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Aortic and peripheral vascular stents<br \/>\nManagement of carotid artery disease<br \/>\nManagement strategies in the presence of frailty<br \/>\nHypertension<br \/>\nLimb salvage<br \/>\nWound management<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Plastic and Reconstructive Surgery\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Scar minimization<br \/>\nGrafting for burns<br \/>\nPost burn rehabilitation<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n          <\/div>\n      \n      \n    <\/div>\n\n  <\/div>\n\n\n\n\n\n  <\/div><\/div>\n\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--featured-block image-left white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          <a name=\"Basic\">Basic Science Research<\/a>\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p><strong>The Department of Surgery\u2019s research contributes to progress in the surgical field.<\/strong><\/p>\n<p>Investigative research into the mysteries of how the body functions leads to greater understanding of the interdependency of all medical disciplines.<\/p>\n\n\n\n<\/div>\n      \n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/surgery\/wp-content\/uploads\/sites\/45\/2024\/07\/Hong-712x768.jpg\"\n                    data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Dr. Young-Kwon Hong in his lab\"\n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n            \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--stacking-cards \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--stacking-cards\"\n    \n      >\n\n    \n  <div class=\"outer-wrapper\">\n    <div class=\"inner-wrapper\">\n      \n                <div class=\"cards-container\">\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Heart Valve Research\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Historically, the main activities of the Heart Valve Laboratory have been the study the structure and function relationship of heart valve tissues.<\/p>\n<p><strong>Previous approaches to studying heart valve biomechanics have included:<\/strong><\/p>\n<ul>\n<li>Selective enzymatic digestion and biomechanical testing<\/li>\n<li>Materials testing and constitutive modeling<\/li>\n<li>Histologic and electron microscopy<\/li>\n<\/ul>\n<p>New areas of investigation have built upon this basic understanding of valve function. The group has explored computational modeling as a tool for the study of soft tissue biomechanics, and tissue engineering as a means of fabricating the complex biological structures directly in the laboratory.<\/p>\n<p>Also notable has been the work towards developing tissue-engineered heart valves, using the biological materials found in the natural tissues \u2014 elastin, collagen and glycosaminoglycans. These molecules can be synthesized by cells in culture or purified from tissues, then manipulated to mimic the normal structural framework of the aortic valve. This approach is particularly relevant to connective tissues that have limited ability for self-repair, like the cardiac valves.<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Xenotransplantation\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Organs derived from pigs (xenografts) represent a solution to the severe organ shortage that currently plagues human organ transplantation. The Xenotransplantation Laboratory, led by Mary Kearns-Jonker, PhD, is studying the immunology of xenograft rejection and the application of gene therapy to induce transplantation tolerance.<\/p>\n<p>Ongoing research projects include:<\/p>\n<ul>\n<li>Analysis of immunoglobulin genes used by organ recipients to target transplanted xenografts<\/li>\n<li>Analysis of the molecular structure of xenoantibody-antigen binding, making use of site-directed mutagenesis and computer modeling<\/li>\n<li>Development of treatment strategies to prevent graft rejection, including the application of anti-idiotypic antibodies and small molecular inhibitors designed to specifically target the xenoantibody binding site<\/li>\n<li>The application of gene therapy to induce transplant tolerance<\/li>\n<\/ul>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n                  <div class=\"card\">\n\n                      <div class=\"title-description\">\n\n                                                          \n<div class=\"f--field f--cta-title\">\n\n    \n  <h3>\n          Mesenchymal Stem Cells in Autograft Fibrosis\n      <\/h3>\n\n\n<\/div>\n                          \n                                                            \n<div class=\"f--field f--description\">\n\n    \n  <p>Chronic rejection is a serious complication of organ transplantation, even in the presence of immunosuppression. Chronic rejection typically results in fibrosis of the graft \u2014 the laying down of excess extra cellular matrix until the organ becomes dysfunctional. Despite the widely appreciated magnitude of the problem and the numerous research efforts to control it, effective therapies to control allograft fibrosis are lacking. Fibroblasts are the sole cell type that forms the scar tissue that eventually leads to the dysfunction of the transplanted organs. The mechanisms that control the recruitment, differentiation and proliferation of intragraft fibroblasts are poorly understood. Recent data have suggested that proliferating intragraft fibroblasts are derived from transplant recipients. New findings indicate that mesenchymal stem cells (MSC) play an important role in the development of allograft fibrosis. The long-term goals of the research program are to apply genetic and cellular therapies for chronic rejection of solid organ transplants.<\/p>\n\n\n\n<\/div>\n                          \n                      <\/div>\n\n\n                      \n                  <\/div>\n\n              \n          <\/div>\n      \n      \n    <\/div>\n\n  <\/div>\n\n\n\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-15","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Research - Department of Surgery<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/keck.usc.edu\/surgery\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research\" \/>\n<meta property=\"og:url\" content=\"https:\/\/keck.usc.edu\/surgery\/research\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Surgery\" \/>\n<meta property=\"article:modified_time\" content=\"2024-07-27T00:06:27+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/surgery\\\/research\\\/\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/surgery\\\/research\\\/\",\"name\":\"Research - 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