{"id":72,"date":"2023-08-23T21:38:58","date_gmt":"2023-08-23T21:38:58","guid":{"rendered":"https:\/\/keck.usc.edu\/zilkha\/?page_id=72"},"modified":"2023-08-23T22:21:07","modified_gmt":"2023-08-23T22:21:07","slug":"labs","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/zilkha\/research\/labs\/","title":{"rendered":"Labs"},"content":{"rendered":"\n\n\n\n\n    \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/zilkha\/\"  aria-label=\"Read more about Zilkha Neurogenetic Institute\">Zilkha Neurogenetic Institute<\/a>\n\n\n\n<\/div>\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/zilkha\/research\/\"  aria-label=\"Read more about Research\">Research<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n  <h1>Labs<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/keck.usc.edu\/zilkha\/support-zni\/\"\n    aria-label=\"Read&#x20;more&#x20;about&#x20;Support&#x20;ZNI\">\n        Support ZNI\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                                  In This Section\n                                <svg class=\"menu\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" 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xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-158\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/research\/coresandcenters\/multi-photon-microscopy-core\/\" >Multi-Photon Microscopy Core<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-161\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/research\/coresandcenters\/functional-biological-imaging-core\/\" >Biological Imaging and Spectroscopy Center<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    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             <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-105 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/training-education\/graduate-programs\/\" >Graduate Programs<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Graduate Programs\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-110\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/training-education\/graduate-programs\/zach-hall-travel-award\/\" >Zach Hall Travel Award<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-115\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/training-education\/post-doctoral-trainees\/\" >Post-Doctoral Trainees<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-118\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/faculty\/\" >Faculty<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-141\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/support-zni\/\" >Support ZNI<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-119 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/contact\/\" >Contact<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Contact\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-124\">\n      <a href=\"https:\/\/keck.usc.edu\/zilkha\/reserve-a-conference-room\/\" >Reserve a Conference Room<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <\/ul><!-- m--menu -->\n<\/nav>\n\n            <\/div>\n                  <\/div>\n        <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/keck.usc.edu\/zilkha\/wp-content\/uploads\/sites\/37\/2023\/08\/zilkha-labs-1280x720.jpg\" alt=\"One of many labs at ZNI with world-class facilities and people.\" width=\"1280\" height=\"720\" \/><\/p>\n<h3>Inside ZNI&#8217;s Integrated Labs &amp; Facilities<\/h3>\n<p>At the Zilkha Neurogenetic Institute (ZNI), our award-winning building is home to state-of-the-art laboratories run by top-tier scientists who are achieving strong recognition for their research into the areas of receptor biology, gene regulation, cellular and systems neurobiology, molecular epidemiology, and developmental therapeutics.<\/p>\n<p>ZNI hosts more than 30 active laboratories in over 70,000 square feet of lab space. In addition to a caf\u00e9, collaboration rooms, offices and a 40-seat multi-media presentation room, our six-story, 125,000-square-foot building includes an 8,100-square-foot vivarium, tissue culture rooms, cold rooms, crystallography, crystal growing, dark rooms, sequencing and a 700MHz\/54mm ultra shield magnet. With these tools, our scientists are conducting the following research.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n\n\n              \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--accordions \"\n\n  \n   aria-label=\"Content Accordions\"\n  \n  \n  \n  \n  >\n  <div class=\"c--component c--accordions\"\n    \n      >\n\n    \n      <div class=\"header-container\">\n\n                  \n<div class=\"f--field f--section-title\">\n\n    \n  <h2>\n          Labs By Area\n      <\/h2>\n\n\n<\/div>\n      \n      \n    <\/div>\n  \n      <ul>\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-1-u-pX5yHKZz\" aria-controls=\"section-1-1-u-pX5yHKZz\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Alzheimer&#8217;s and Related Diseases<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-1-u-pX5yHKZz\" role=\"region\" aria-labelledby=\"heading-1-1-u-pX5yHKZz\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Karen-Ting-Chang\/\" target=\"_blank\" rel=\"noopener\">The Chang Lab<\/a><\/strong><br \/>\nKaren Chang, PhD<br \/>\nTrying to determine the role nebula\/DSCR1 plays in ameliorating axonal transport defects and memory loss associated with Alzheimer\u2019s disease. Also trying to identify the genotype to phenotype correlations in Down syndrome.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a class=\"read-more\" href=\"http:\/\/donglab.loni.usc.edu\/\" target=\"_blank\" rel=\"noopener\">The Dong Lab<\/a><\/strong><br \/>\nHong-Wei Dong, MD, PhD<br \/>\nStudying the organizational principle of the brain wiring and how these circuits are disrupted in mouse models of Huntington\u2019s and Alzheimer\u2019s diseases.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a class=\"read-more\" href=\"https:\/\/keck.usc.edu\/faculty-search\/Ralf-Langen\/\" target=\"_blank\" rel=\"noopener\">The Langen Lab<\/a><\/strong><br \/>\nRalf Langen, PhD<br \/>\nResearching on the basic areas of protein folding and misfolding with particular emphasis on these processes when they occur on or around membranes.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a class=\"read-more\" href=\"http:\/\/siemerlab.usc.edu\/\" target=\"_blank\" rel=\"noopener\">The Siemer Lab<\/a><\/strong><br \/>\nAnsgar Siemer, PhD<br \/>\nDescribing on a structural level how some amyloid fibrils can be toxic and responsible for neurodegenerative diseases, while others have beneficial functions as for example in long-term memory. The latter question is addressed in their research on the Orb2 functional amyloid, which is a key regulator of long-term memory in Drosophila.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a class=\"read-more\" href=\"http:\/\/siemerlab.usc.edu\/psc.html\" target=\"_blank\" rel=\"noopener\">The Protein Structure Group<\/a><\/strong><br \/>\nRalf Langen, PhD, Ansgar Siemer, PhD and Tobias Ulmer, PhD<br \/>\nInvestigating the structure of proteins involved in debilitating diseases such as Alzheimer\u2019s disease, Parkinson\u2019s and Huntington\u2019s disease. Because many disorders of the nervous system are thought to arise from alterations in the structure of cellular proteins, these studies aim to help us understand the molecular basis of neural pathology with a look toward devising new treatments for the cure and prevention of these diseases.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a class=\"read-more\" href=\"https:\/\/keck.usc.edu\/faculty-search\/Berislav-V-Zlokovic\/\" target=\"_blank\" rel=\"noopener\">The Zlokovic Lab<\/a><\/strong><br \/>\nBerislav Zlokovic, MD, PhD<br \/>\nUnderstanding the role of cerebral blood vessels and the blood-brain barrier (BBB) in pathogenesis of neurodegenerative disorders such as Alzheimer\u2019s disease and amytrophic lateral sclerosis (ALS) for the foundation of developing new therapies for AD, related neurodegenerative disorders and stroke.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-2-u-pX5yHKZz\" aria-controls=\"section-1-2-u-pX5yHKZz\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Circuits<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-2-u-pX5yHKZz\" role=\"region\" aria-labelledby=\"heading-1-2-u-pX5yHKZz\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><strong><a href=\"http:\/\/www-hsc.usc.edu\/~rchow\/Home.html\" target=\"_blank\" rel=\"noopener\">The Chow Lab<\/a><\/strong><br \/>\nRobert Chow, MD, PhD<br \/>\nAdvancing our understanding of how neuronal and hormone secretion (exocytosis) is controlled in normal and pathological states. Part of the lab focuses on fundamental mechanisms (SNARE-mediated secretion) and the other on disease processes (diabetes, retinal and neuro- degeneration) or how to treat diseases (retinal degeneration).<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Derek-S.-Sieburth\/\" target=\"_blank\" rel=\"noopener\">The Sieburth Lab<\/a><\/strong><br \/>\nDerek Sieburth, PhD<br \/>\nCombining behavioral, genetic, RNA interference and live imaging techniques to dissect synaptic function at a systems and molecular level in the C. elegans model.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Li-Zhang\/\" target=\"_blank\" rel=\"noopener\">The Zhang Lab<\/a><\/strong><br \/>\nLi Zhang, PhD<br \/>\nUnderstanding the structure and function of neural circuits so as to decipher the brain, which includes four aspects: 1) how neural circuits assemble and operate; 2) how circuit structure determines behavioral function; 3) how circuit functions are modulated; and 4) how circuit disorders lead to brain disorders. Huizhong Tao\u2019s work also explores establishment and development of functional visual circuits (please see The Tao Lab).<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-3-u-pX5yHKZz\" aria-controls=\"section-1-3-u-pX5yHKZz\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Genomics<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-3-u-pX5yHKZz\" role=\"region\" aria-labelledby=\"heading-1-3-u-pX5yHKZz\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/David-V.-Conti\/\" target=\"_blank\" rel=\"noopener\">The Conti Lab<\/a><\/strong><br \/>\nDavid Conti, PhD<br \/>\nDeveloping novel statistical methods to analyze next-generation sequencing data to discovery genetic variants involved in disease. This work is heavily integrated into his applied collaborations examining the genetic contribution to smoking progression and cessation, multiple sclerosis, colon and prostate cancer, asthma, lymphoma and psychiatric disorders.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Gabriel-Zada\/\">The Zada Lab<\/a><\/strong><br \/>\nGabriel Zada, MD<br \/>\nUtilizing next-generation genomic and epigenomic profiling (i.e. DNA Methylation analysis) to study the behavior of various brain tumors. In particular, he is interested in studying the process of local tumor invasion and developing molecular classification systems for various skull base tumors, including pituitary tumors and meningiomas. He is also working to develop novel treatment strategies for skull base tumors using intranasal therapy systems.<br \/>\n&nbsp;<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-4-u-pX5yHKZz\" aria-controls=\"section-1-4-u-pX5yHKZz\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Hearing\/Ear<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-4-u-pX5yHKZz\" role=\"region\" aria-labelledby=\"heading-1-4-u-pX5yHKZz\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Radha-Kalluri\/\" target=\"_blank\" rel=\"noopener\">The Kalluri Lab<\/a><\/strong><br \/>\nRadha Kalluri, PhD<br \/>\nExamining how biophysical differences between subpopulations of bipolar afferent neurons in the auditory and vestibular systems influence their function and their susceptibility to damage.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Takahiro-Ohyama\/\" target=\"_blank\" rel=\"noopener\">The Ohyama Lab<\/a><\/strong><br \/>\nTakahiro Ohyama, PhD<br \/>\nInvestigating how the cochlea, the auditory organ, develops during embryonic development. They discovered BMP signaling pathway is important for cell fate decision between sensory and non-sensory structure of mammalian cochlea. The Ohyama lab is also analyzing the mechanisms how migrating neural crest cells are incorporated into the non-sensory structure of developing cochlea, which is crucial for proper hearing functions. These projects aim to understand disease mechanisms of hearing impairment and develop translational research such as regeneration of auditory cells.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-5-u-pX5yHKZz\" aria-controls=\"section-1-5-u-pX5yHKZz\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Psychiatric Genetics<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-5-u-pX5yHKZz\" role=\"region\" aria-labelledby=\"heading-1-5-u-pX5yHKZz\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Alexandre-Bonnin\/\"><strong>The Bonnin Lab<\/strong><\/a><br \/>\nAlex Bonnin, PhD<br \/>\nInvestigating how placental function affects fetal brain development, specifically looking at the impact of maternal infections in pregnancy and separately and the effects of maternal stress and antidepressant treatment. This research uncovers new molecular pathways for the developmental origins of mental disorders.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Marcelo-Pablo-Coba\/\" target=\"_blank\" rel=\"noopener\">The Coba Lab<\/a><\/strong><br \/>\nMarcelo Coba, PhD<br \/>\nInvestigating how candidate risk factors associated to schizophrenia and other psychiatric disorders work together in common signaling pathways, combining state-of-the-art mass spectrometry, proteomics, bioinformatics, mouse genetics and human stem cell methods. This strategy helps determine core signaling mechanisms and protein complexes, altered through development in schizophrenia, providing new molecular targets for treatment.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-6-u-pX5yHKZz\" aria-controls=\"section-1-6-u-pX5yHKZz\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Vascular<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-6-u-pX5yHKZz\" role=\"region\" aria-labelledby=\"heading-1-6-u-pX5yHKZz\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <div>\n<div>\n<p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/William-Mack\/\" target=\"_blank\" rel=\"noopener\">The Mack Lab<\/a><\/strong><br \/>\nWilliam Mack, MD<br \/>\nDeploying an experimental strategy to determine the effects of air pollution on acute stroke, which is a leading cause of death and disability worldwide. He is further investigating innovative treatment platforms for rapid delivery of neuroprotective agents to otherwise inaccessible cortical territories in the setting of acute stroke.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Janos-Peti-Peterdi\/\" target=\"_blank\" rel=\"noopener\">The Peti-Peterdi Lab<\/a><\/strong><br \/>\nJanos Peti-Peterdi, MD, PhD<br \/>\nExploring renal (patho) physiology, specifically the intrarenal mechanisms involved in the control of blood pressure and body fluid balance under normal and disease conditions (hypertension, diabetes).<\/p>\n<div><\/div>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-7-u-pX5yHKZz\" aria-controls=\"section-1-7-u-pX5yHKZz\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Vision<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-7-u-pX5yHKZz\" role=\"region\" aria-labelledby=\"heading-1-7-u-pX5yHKZz\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><strong><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Jeannie-Chen\/\" target=\"_blank\" rel=\"noopener\">The Chen Lab<\/a><\/strong><br \/>\nJeannie Chen, PhD<br \/>\nUnderstanding how an intracellular signaling cascade is regulated within rod and cone photoreceptor cells, and how this contributes to the specialized ability of these cells to detect dim light and bright light, respectively and how mutations within this signaling cascade leads to blindness.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/keck.usc.edu\/faculty-search\/Huizhong-Tao\/\" target=\"_blank\" rel=\"noopener\"><strong>The Tao Lab<\/strong><\/a><br \/>\nHuizhong Tao, PhD<br \/>\nExploring how functional visual circuits are organized to achieve specific cortical processing functions and how these circuits are established during development. She is currently examining how neural activity of various patterns leads to modulations of synaptic connections and shapes the formation of visual circuits.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n          <\/ul>\n  \n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":3,"featured_media":0,"parent":19,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-72","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.5 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Labs - Zilkha Neurogenetic Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/keck.usc.edu\/zilkha\/research\/labs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Labs\" \/>\n<meta property=\"og:url\" content=\"https:\/\/keck.usc.edu\/zilkha\/research\/labs\/\" \/>\n<meta property=\"og:site_name\" content=\"Zilkha Neurogenetic Institute\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-23T22:21:07+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/zilkha\\\/research\\\/labs\\\/\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/zilkha\\\/research\\\/labs\\\/\",\"name\":\"Labs - 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