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John M. Ringman, MD, MS

Professor of Clinical Neurology

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Email ringman@usc.edu
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Publications

  • Surface-Based Probabilistic Fiber Tracking in Superficial White Matter IEEE Trans Med Imaging. 2024 Mar; 43(3):1113-1124. . View in PubMed
  • Vessel density mapping of small cerebral vessels on 3D high resolution black blood MRI Neuroimage. 2024 Feb 01; 286:120504. . View in PubMed
  • Age of onset predicted by Aß profiling in a novel PSEN1 (I180F) mutation Neurosci Lett. 2024 Jan 18; 820:137591. . View in PubMed
  • Systematic proteomics in Autosomal dominant Alzheimer’s disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways medRxiv. 2024 Jan 13. . View in PubMed
  • Association Between Self- and Proxy-Reported Depression and Quality of Life in Mild-Moderate Alzheimer’s Disease Am J Geriatr Psychiatry. 2024 01; 32(1):58-67. . View in PubMed
  • Retinotopic degeneration of the retina and optic tracts in autosomal dominant Alzheimer’s disease Alzheimers Dement. 2023 Nov; 19(11):5103-5113. . View in PubMed
  • Use of the Spanish English Neuropsychological Assessment Scale in older adult Latines and those at risk for autosomal dominant Alzheimer’s disease J Clin Exp Neuropsychol. 2023 Aug; 45(6):553-569. . View in PubMed
  • Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer’s disease: the Alzheimer’s Disease Genetics Consortium medRxiv. 2023 Jul 08. . View in PubMed
  • Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function Aging Dis. 2023 May 26. . View in PubMed
  • Vessel Density Mapping of Cerebral Small Vessels on 3D High Resolution Black Blood MRI bioRxiv. 2023 Mar 21. . View in PubMed
  • Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRß, a marker of blood brain barrier breakdown, in older adults Res Sq. 2023 Mar 07. . View in PubMed
  • First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer’s disease: the Dominantly Inherited Alzheimer’s Network Study J Neurol Neurosurg Psychiatry. 2023 05; 94(5):403-405. . View in PubMed
  • Retinal pathological features and proteome signatures of Alzheimer’s disease Acta Neuropathol. 2023 04; 145(4):409-438. . View in PubMed
  • Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease Alzheimers Dement. 2023 02; 19(2):632-645. . View in PubMed
  • Characterization of spastic paraplegia in a family with a novel PSEN1 mutation Brain Commun. 2023; 5(2):fcad030. . View in PubMed
  • The association between white matter hyperintensities and amyloid and tau deposition Neuroimage Clin. 2023; 38:103383. . View in PubMed
  • FMRI Complexity Correlates with Tau-PET and Cognitive Decline in Late-Onset and Autosomal Dominant Alzheimer’s Disease J Alzheimers Dis. 2023; 95(2):437-451. . View in PubMed
  • Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease Ann Neurol. 2022 11; 92(5):729-744. . View in PubMed
  • Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease Alzheimers Dement. 2022 10; 18(10):1754-1764. . View in PubMed
  • Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer’s disease Neurobiol Aging. 2022 04; 112:39-54. . View in PubMed
  • Autosomal dominant and sporadic late onset Alzheimer’s disease share a common in vivo pathophysiology Brain. 2022 10 21; 145(10):3594-3607. . View in PubMed
  • Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer’s disease Alzheimers Res Ther. 2022 11 15; 14(1):173. . View in PubMed
  • Front Aging Neurosci. 2022; 14:883131. . View in PubMed
  • Enhanced Association of Tau Pathology and Cognitive Impairment in Mild Cognitive Impairment Subjects with Behavior Symptoms J Alzheimers Dis. 2022; 87(2):557-568. . View in PubMed
  • Cerebral Amyloid Angiopathy-related Inflammation Presenting With a Cystic Lesion in Young-onset Alzheimer Disease Alzheimer Dis Assoc Disord. 2021 Jul-Sep 01; 35(3):265-268. . View in PubMed
  • Comparing amyloid-ß plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease Acta Neuropathol. 2021 10; 142(4):689-706. . View in PubMed
  • Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer’s disease: a cross-sectional study Lancet Neurol. 2021 08; 20(8):615-626. . View in PubMed
  • Past, present and future role of retinal imaging in neurodegenerative disease Prog Retin Eye Res. 2021 07; 83:100938. . View in PubMed
  • “My backpack is so heavy”: Experiences of Latino caregivers of family with early-onset Alzheimer’s J Am Geriatr Soc. 2021 06; 69(6):1539-1547. . View in PubMed
  • MarkVCID cerebral small vessel consortium: IEnrollment, clinical, fluid protocols. Alzheimers Dement. 2021 04; 17(4):704-715. . View in PubMed
  • Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study J Cereb Blood Flow Metab. 2021 03; 41(3):670-683. . View in PubMed
  • Volumetric distribution of perivascular space in relation to mild cognitive impairment Neurobiol Aging. 2021 03; 99:28-43. . View in PubMed
  • Reaction time and response inhibition in autosomal dominant Alzheimer’s disease Brain Cogn. 2021 02; 147:105656. . View in PubMed
  • Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease Front Neurosci. 2021; 15:627627. . View in PubMed
  • Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer’s disease Alzheimers Dement (Amst). 2021; 13(1):e12197. . View in PubMed
  • Abnormal retinal capillary blood flow in autosomal dominant Alzheimer’s disease Alzheimers Dement (Amst). 2021; 13(1):e12162. . View in PubMed
  • Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease Neurology. 2021 03 23; 96(12):e1632-e1645. . View in PubMed
  • Autosomal dominant early onset Alzheimer’s disease in the Mexican state of Jalisco: High frequency of the mutation PSEN1 c1292C>A and phenotypic profile of patients. Am J Med Genet C Semin Med Genet. 2020 12; 184(4):1023-1029. . View in PubMed
  • A probabilistic atlas of locus coeruleus pathways to transentorhinal cortex for connectome imaging in Alzheimer’s disease Neuroimage. 2020 12; 223:117301. . View in PubMed
  • Emotional detachment, gait ataxia, and cerebellar dysconnectivity associated with compound heterozygous mutations in the SPG7 gene Neurocase. 2020 10; 26(5):299-304. . View in PubMed
  • A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid Alzheimers Dement. 2020 06; 16(6):821-830. . View in PubMed
  • APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline Nature. 2020 05; 581(7806):71-76. . View in PubMed
  • Lower retinal capillary density in minimal cognitive impairment among older Latinx adults Alzheimers Dement (Amst). 2020; 12(1):e12071. . View in PubMed
  • Probing Estrogen Sulfotransferase-Mediated Inflammation with [11C]-PiB in the Living Human Brain J Alzheimers Dis. 2020; 73(3):1023-1033. . View in PubMed
  • Comparison Between Blood-Brain Barrier Water Exchange Rate and Permeability to Gadolinium-Based Contrast Agent in an Elderly Cohort Front Neurosci. 2020; 14:571480. . View in PubMed
  • Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies Alzheimers Dement (Amst). 2019 Dec; 11:180-190. . View in PubMed
  • Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders Alzheimer Dis Assoc Disord. 2019 Oct-Dec; 33(4):327-330. . View in PubMed
  • Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing Nat Genet. 2019 Sep; 51(9):1423-1424. . View in PubMed
  • 1H MRS spectroscopy in preclinical autosomal dominant Alzheimer disease Brain Imaging Behav. 2019 Aug; 13(4):925-932. . View in PubMed
  • Treatment Options for Agitation in Dementia Curr Treat Options Neurol. 2019 Jun 24; 21(7):30. . View in PubMed
  • A mixed-methods study of cultural beliefs about dementia and genetic testing among Mexicans and Mexican-Americans at-risk for autosomal dominant Alzheimer’s disease J Genet Couns. 2019 10; 28(5):921-932. . View in PubMed
  • Historical Migration revealed through a Case of Autosomal Dominant Alzheimer’s Disease P R Health Sci J. 2019 09; 38(3):144-147. . View in PubMed
  • Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer’s disease Alzheimers Dement. 2019 05; 15(5):655-665. . View in PubMed
  • Mapping water exchange across the blood-brain barrier using 3D diffusion-prepared arterial spin labeled perfusion MRI Magn Reson Med. 2019 05; 81(5):3065-3079. . View in PubMed
  • Seizures as an early symptom of autosomal dominant Alzheimer’s disease Neurobiol Aging. 2019 04; 76:18-23. . View in PubMed
  • Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing Nat Genet. 2019 03; 51(3):414-430. . View in PubMed
  • Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction Nat Med. 2019 02; 25(2):270-276. . View in PubMed
  • Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease Nat Med. 2019 02; 25(2):277-283. . View in PubMed
  • Cognitive symptoms of Alzheimer’s disease: clinical management and prevention BMJ. 2019 12 06; 367:l6217. . View in PubMed
  • Homozygosity for the A431E mutation in PSEN1 presenting with a relatively aggressive phenotype Neurosci Lett. 2019 04 23; 699:195-198. . View in PubMed
  • Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer’s disease Brain. 2019 05 01; 142(5):1429-1440. . View in PubMed
  • CSF progranulin increases in the course of Alzheimer’s disease and is associated with sTREM2, neurodegeneration and cognitive decline EMBO Mol Med. 2018 12; 10(12). . View in PubMed
  • Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer’s disease Alzheimers Dement. 2018 11; 14(11):1427-1437. . View in PubMed
  • Impairment of memory generalization in preclinical autosomal dominant Alzheimer’s disease mutation carriers Neurobiol Aging. 2018 05; 65:149-157. . View in PubMed
  • Presymptomatic atrophy in autosomal dominant Alzheimer’s disease: A serial magnetic resonance imaging study Alzheimers Dement. 2018 01; 14(1):43-53. . View in PubMed
  • Regional association of pCASL-MRI with FDG-PET and PiB-PET in people at risk for autosomal dominant Alzheimer’s disease Neuroimage Clin. 2018; 17:751-760. . View in PubMed
  • Preferential degradation of cognitive networks differentiates Alzheimer’s disease from ageing Brain. 2018 05 01; 141(5):1486-1500. . View in PubMed
  • A probabilistic atlas of human brainstem pathways based on connectome imaging data Neuroimage. 2018 04 01; 169:227-239. . View in PubMed
  • Utility of perfusion PET measures to assess neuronal injury in Alzheimer’s disease Alzheimers Dement (Amst). 2018; 10:669-677. . View in PubMed
  • Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease Neurology. 2018 10 02; 91(14):e1295-e1306. . View in PubMed
  • White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease PLoS One. 2018; 13(5):e0195838. . View in PubMed
  • Attitudes toward clinical trials across the Alzheimer’s disease spectrum Alzheimers Res Ther. 2017 Oct 04; 9(1):81. . View in PubMed
  • A novel PSEN1 (S230N) mutation causing early-onset Alzheimer’s Disease associated with prosopagnosia, hoarding, and Parkinsonism Neurosci Lett. 2017 Sep 14; 657:11-15. . View in PubMed
  • Patient and caregiver reactions to clinical amyloid imaging Alzheimers Dement. 2017 Aug; 13(8):924-932. . View in PubMed
  • Update on Alzheimer’s and the Dementias: Introduction Neurol Clin. 2017 May; 35(2):171-174. . View in PubMed
  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer’s disease Nat Genet. 2017 09; 49(9):1373-1384. . View in PubMed
  • Alzheimer and the Dementias Neurol Clin. 2017 05; 35(2):ix-x. . View in PubMed
  • Two Novel Mutations in the First Transmembrane Domain of Presenilin1 Cause Young-Onset Alzheimer’s Disease J Alzheimers Dis. 2017; 58(4):1035-1041. . View in PubMed
  • Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer’s disease Sci Rep. 2017 04 27; 7(1):1225. . View in PubMed
  • Neuropsychological Profiles Differentiate Alzheimer Disease from Subcortical Ischemic Vascular Dementia in an Autopsy-Defined Cohort Dement Geriatr Cogn Disord. 2017; 44(1-2):1-11. . View in PubMed
  • A comparison of theoretical and statistically derived indices for predicting cognitive decline Alzheimers Dement (Amst). 2017; 6:171-181. . View in PubMed
  • Neurological manifestations of autosomal dominant familial Alzheimer’s disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS) Lancet Neurol. 2016 Dec; 15(13):1317-1325. . View in PubMed
  • White matter hyperintensities are a core feature of Alzheimer’s disease: Evidence from the dominantly inherited Alzheimer network Ann Neurol. 2016 Jun; 79(6):929-39. . View in PubMed
  • Improvement of Dream Enactment Behavior Associated With Levetiracetam Treatment in Dementia With Lewy Bodies Alzheimer Dis Assoc Disord. 2016 Apr-Jun; 30(2):175-7. . View in PubMed
  • Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database J Neuropathol Exp Neurol. 2016 Mar; 75(3):284-90. . View in PubMed
  • Widespread white matter and conduction defects in PSEN1-related spastic paraparesis Neurobiol Aging. 2016 11; 47:201-209. . View in PubMed
  • BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease Brain. 2016 10; 139(Pt 10):2766-2777. . View in PubMed
  • Assessing intracranial vascular compliance using dynamic arterial spin labeling Neuroimage. 2016 Jan 01; 124(Pt A):433-441. . View in PubMed
  • Critical review of the Appropriate Use Criteria for amyloid imaging: Effect on diagnosis and patient care Alzheimers Dement (Amst). 2016; 5:15-22. . View in PubMed
  • Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer’s Disease: Results from the DIAN Study Group PLoS One. 2016; 11(3):e0152082. . View in PubMed
  • Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer’s Disease: Results from the DIAN Study Group PLoS One. 2016; 11(9):e0163669. . View in PubMed
  • Are Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease “Separate but Equal”? JAMA Neurol. 2016 09 01; 73(9):1060-1.. View in PubMed
  • Impairments in the Face-Processing Network in Developmental Prosopagnosia and Semantic Dementia Cogn Behav Neurol. 2015 Dec; 28(4):188-97. . View in PubMed
  • Daily Activity Abilities in MCI, Alzheimer’s Disease, and Healthy Controls GeroPsych (Bern). 2015 Dec; 28(4):191-200. . View in PubMed
  • Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease Neurology. 2015 Sep 01; 85(9):790-8. . View in PubMed
  • Early behavioural changes in familial Alzheimer’s disease in the Dominantly Inherited Alzheimer Network Brain. 2015 Apr; 138(Pt 4):1036-45. . View in PubMed
  • A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy JAMA Neurol. 2015 Apr; 72(4):414-22. . View in PubMed
  • Donepezil treatment in ethnically diverse patients with Alzheimer disease Am J Geriatr Psychiatry. 2015 Apr; 23(4):384-390. . View in PubMed
  • Factors associated with the onset and persistence of post-lumbar puncture headache JAMA Neurol. 2015 Mar; 72(3):325-32. . View in PubMed
  • Rarity of the Alzheimer disease-protective APP A673T variant in the United States JAMA Neurol. 2015 Feb; 72(2):209-16. . View in PubMed
  • Conceptualization and assessment of vulnerability in a complex international Alzheimer’s research study Am J Bioeth. 2015; 15(4):87-9. . View in PubMed
  • A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer’s disease Alzheimers Res Ther. 2015; 7(1):50. . View in PubMed
  • Use of the MoCA in Detecting Early Alzheimer’s Disease in a Spanish-Speaking Population with Varied Levels of Education Dement Geriatr Cogn Dis Extra. 2015 Jan-Apr; 5(1):85-95. . View in PubMed
  • JAMA Neurol. 2014 Dec; 71(12):1481-9. . View in PubMed
  • Genetic heterogeneity in Alzheimer disease and implications for treatment strategies Curr Neurol Neurosci Rep. 2014 Nov; 14(11):499. . View in PubMed
  • Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study JAMA Neurol. 2014 Nov; 71(11):1394-404. . View in PubMed
  • Functional connectivity in autosomal dominant and late-onset Alzheimer disease JAMA Neurol. 2014 Sep; 71(9):1111-22. . View in PubMed
  • Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis Neurology. 2014 Jul 15; 83(3):253-60. . View in PubMed
  • Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease JAMA Neurol. 2014 Jul 01; 71(7):878-83. . View in PubMed
  • Younger age of dementia diagnosis in a Hispanic population in southern California Int J Geriatr Psychiatry. 2014 Jun; 29(6):586-93. . View in PubMed
  • Age effects on cortical thickness in cognitively normal elderly individuals Dement Geriatr Cogn Dis Extra. 2014 May; 4(2):221-7. . View in PubMed
  • The “Alzheimer’s type” profile of semantic clustering in amnestic mild cognitive impairment J Int Neuropsychol Soc. 2014 Apr; 20(4):402-12. . View in PubMed
  • Reliability of two-dimensional and three-dimensional pseudo-continuous arterial spin labeling perfusion MRI in elderly populations: comparison with 15O-water positron emission tomography J Magn Reson Imaging. 2014 Apr; 39(4):931-9. . View in PubMed
  • Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer’s disease Sci Transl Med. 2014 Mar 05; 6(226):226ra30. . View in PubMed
  • A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer’s disease in an African-American woman J Alzheimers Dis. 2014; 40(2):271-5. . View in PubMed
  • Neuropathologic correlates of trial-related instruments for Alzheimer’s disease Am J Neurodegener Dis. 2014; 3(1):45-9. . View in PubMed
  • Memory performance and fMRI signal in presymptomatic familial Alzheimer’s disease Hum Brain Mapp. 2013 Dec; 34(12):3308-19. . View in PubMed
  • Regional variability of imaging biomarkers in autosomal dominant Alzheimer’s disease Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4502-9. . View in PubMed
  • Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults Neuroimage. 2013 Nov 15; 82:146-53. . View in PubMed
  • The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study Neurology. 2013 Oct 15; 81(16):1425-33. . View in PubMed
  • The impact of the availability of prevention studies on the desire to undergo predictive testing in persons at risk for autosomal dominant Alzheimer’s disease Contemp Clin Trials. 2013 Sep; 36(1):256-62. . View in PubMed
  • Impaired default network functional connectivity in autosomal dominant Alzheimer disease Neurology. 2013 Aug 20; 81(8):736-44. . View in PubMed
  • Similar verbal fluency patterns in amnestic mild cognitive impairment and Alzheimer’s disease Arch Clin Neuropsychol. 2013 Aug; 28(5):400-10. . View in PubMed
  • Complexity and synchronicity of resting state blood oxygenation level-dependent (BOLD) functional MRI in normal aging and cognitive decline J Magn Reson Imaging. 2013 Jul; 38(1):36-45. . View in PubMed
  • New genes and new insights from old genes: update on Alzheimer disease Continuum (Minneap Minn). 2013 Apr; 19(2 Dementia):358-71. . View in PubMed
  • Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder J Psychiatr Res. 2013 Apr; 47(4):494-504. . View in PubMed
  • Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer’s disease mutations J Neurol Neurosurg Psychiatry. 2013 Feb; 84(2):154-62. . View in PubMed
  • Estimating sample sizes for predementia Alzheimer’s trials based on the Alzheimer’s Disease Neuroimaging Initiative Neurobiol Aging. 2013 Jan; 34(1):62-72. . View in PubMed
  • 1a,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-ß phagocytosis and inflammation in Alzheimer’s disease patients J Alzheimers Dis. 2013; 34(1):155-70. . View in PubMed
  • Agitation and psychosis associated with dementia with lewy bodies exacerbated by modafinil use Am J Alzheimers Dis Other Demen. 2012 Nov; 27(7):468-73. . View in PubMed
  • Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network Clin Investig (Lond). 2012 Oct 01; 2(10):975-984. . View in PubMed
  • Clinical and biomarker changes in dominantly inherited Alzheimer’s disease N Engl J Med. 2012 Aug 30; 367(9):795-804. . View in PubMed
  • Evidence for a role of the rare pA152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer’s diseases. Hum Mol Genet. 2012 Aug 01; 21(15):3500-12. . View in PubMed
  • Novel late-onset Alzheimer disease loci variants associate with brain gene expression Neurology. 2012 Jul 17; 79(3):221-8. . View in PubMed
  • The exception makes the rule: not all Aß plaques are created equal Neurology. 2012 Jul 17; 79(3):206-7. . View in PubMed
  • Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures Arch Neurol. 2012 Jul; 69(7):836-41. . View in PubMed
  • Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype Arch Neurol. 2012 Jun; 69(6):757-64. . View in PubMed
  • Relationship of a variant in the NTRK1 gene to white matter microstructure in young adults J Neurosci. 2012 Apr 25; 32(17):5964-72. . View in PubMed
  • Increased fMRI signal with age in familial Alzheimer’s disease mutation carriersNeurobiol Aging. 2012 Feb; 33(2):424. e11-21. . View in PubMed
  • Comparison of clinical characteristics between familial and non-familial early onset Alzheimer’s disease J Neurol. 2012 10; 259(10):2182-8. . View in PubMed
  • Cerebrospinal fluid biomarkers and proximity to diagnosis in preclinical familial Alzheimer’s disease Dement Geriatr Cogn Disord. 2012; 33(1):1-5. . View in PubMed
  • Oral curcumin for Alzheimer’s disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study Alzheimers Res Ther. 2012; 4(5):43. . View in PubMed
  • Plasma methionine sulfoxide in persons with familial Alzheimer’s disease mutations Dement Geriatr Cogn Disord. 2012; 33(4):219-25. . View in PubMed
  • Conformation-dependent oligomers in cerebrospinal fluid of presymptomatic familial Alzheimer’s disease mutation carriers Dement Geriatr Cogn Dis Extra. 2012 Jan; 2(1):652-7. . View in PubMed
  • Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations Arch Neurol. 2012 Jan; 69(1):96-104. . View in PubMed
  • Should persons with autosomal dominant AD be included in clinical trials? Alzheimers Res Ther. 2011 May 23; 3(3):18.. View in PubMed
  • Common Alzheimer’s disease risk variant within the CLU gene affects white matter microstructure in young adults J Neurosci. 2011 May 04; 31(18):6764-70. . View in PubMed
  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer’s disease Nat Genet. 2011 May; 43(5):436-41. . View in PubMed
  • Effects of risk genes on BOLD activation in presymptomatic carriers of familial Alzheimer’s disease mutations during a novelty encoding task Cereb Cortex. 2011 Apr; 21(4):877-83. . View in PubMed
  • Neuroimaging measures as endophenotypes in Alzheimer’s disease Int J Alzheimers Dis. 2011 Mar 31; 2011:490140. . View in PubMed
  • Setting the stage for prevention of familial Alzheimer’s disease Lancet Neurol. 2011 Mar; 10(3):200-1. . View in PubMed
  • Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer’s disease due to a novel PSEN1 mutation Neurosci Lett. 2011 Jan 10; 487(3):287-92. . View in PubMed
  • Autosomal-dominant Alzheimer’s disease: a review and proposal for the prevention of Alzheimer’s disease Alzheimers Res Ther. 2011 Jan 06; 3(1):1. . View in PubMed
  • An update on the diagnosis and management of dementing conditions Rev Neurol Dis. 2011; 8(3-4):e68-87. . View in PubMed
  • Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer’s disease Dement Geriatr Cogn Disord. 2011; 32(2):118-25. . View in PubMed
  • Propositional density and apolipoprotein E genotype among persons at risk for familial Alzheimer’s disease Dement Geriatr Cogn Disord. 2011; 32(3):188-92. . View in PubMed
  • The use of profanity during letter fluency tasks in frontotemporal dementia and Alzheimer disease Cogn Behav Neurol. 2010 Sep; 23(3):159-64. . View in PubMed
  • Insensitivity of visual assessment of hippocampal atrophy in familial Alzheimer’s disease J Neurol. 2010 May; 257(5):839-42. . View in PubMed
  • Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer’s disease Mol Neurodegener. 2010 Jan 14; 5:2. . View in PubMed
  • Mary SEaston Center of Alzheimer’s Disease Research at UCLA: advancing the therapeutic imperative. J Alzheimers Dis. 2010; 19(2):375-88. . View in PubMed
  • Current concepts of mild cognitive impairment and their applicability to persons at-risk for familial Alzheimer’s disease Curr Alzheimer Res. 2009 Aug; 6(4):341-6. . View in PubMed
  • Reduction of SorLA/LR11, a sorting protein limiting beta-amyloid production, in Alzheimer disease cerebrospinal fluid Arch Neurol. 2009 Apr; 66(4):448-57. . View in PubMed
  • Commentary on “a roadmap for the prevention of dementia II: Leon Thal Symposium 2008” Prevention trials in persons at risk for dominantly inherited Alzheimer’s disease: opportunities and challenges. Alzheimers Dement. 2009 Mar; 5(2):166-71. . View in PubMed
  • Diagnosing depression in Alzheimer disease with the national institute of mental health provisional criteria Am J Geriatr Psychiatry. 2008 Jun; 16(6):469-77. . View in PubMed
  • Myopathy associated with chronic orlistat consumption: a case report Neuromuscul Disord. 2008 May; 18(5):410-2. . View in PubMed
  • Mosaicism for trisomy 21 in a patient with young-onset dementia: a case report and brief literature review Arch Neurol. 2008 Mar; 65(3):412-5. . View in PubMed
  • Increased prevalence of significant recurrent headache in preclinical familial Alzheimer’s disease mutation carriers Dement Geriatr Cogn Disord. 2008; 25(4):380-4. . View in PubMed
  • Children of persons with Alzheimer disease: what does the future hold? Alzheimer Dis Assoc Disord. 2008 Jan-Mar; 22(1):6-20.. View in PubMed
  • The Huntington disease of woody guthrie: another man done gone Cogn Behav Neurol. 2007 Dec; 20(4):238-43. . View in PubMed
  • Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer’s disease patients are improved by bisdemethoxycurcumin Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12849-54. . View in PubMed
  • Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer’s disease mutations Brain. 2007 Jul; 130(Pt 7):1767-76. . View in PubMed
  • An experimental approach to detecting dementia in Down syndrome: a paradigm for Alzheimer’s disease Brain Cogn. 2007 Jun; 64(1):92-103. . View in PubMed
  • Performance on MMSE sub-items and education level in presenilin-1 mutation carriers without dementia Int Psychogeriatr. 2007 Apr; 19(2):323-32. . View in PubMed
  • Serendipitous improvement in the Yips associated with memantine use Mov Disord. 2007 Mar 15; 22(4):598-9. . View in PubMed
  • Visualizing language deterioration in progressive aphasias Neurology. 2006 Nov 28; 67(10):1738-9. . View in PubMed
  • The A431E mutation in PSEN1 causing familial Alzheimer’s disease originating in Jalisco State, Mexico: an additional fifteen families Neurogenetics. 2006 Nov; 7(4):277-9. . View in PubMed
  • Donepezil improves cognitive function and reduces decline in activities of daily living in people with severe Alzheimer’s disease Evid Based Ment Health. 2006 Nov; 9(4):104. . View in PubMed
  • The Thr354Ile substitution in PSEN1:: disease-causing mutation or polymorphism? Neurology. 2006 Jun 27; 66(12):1955-6.. View in PubMed
  • Family history of dementia in early-onset versus very late-onset Alzheimer’s disease Int J Geriatr Psychiatry. 2006 Jun; 21(6):597-8. . View in PubMed
  • Current and emerging pharmacological treatment options for dementia Behav Neurol. 2006; 17(1):5-16. . View in PubMed
  • What the study of persons at risk for familial Alzheimer’s disease can tell us about the earliest stages of the disorder: a review J Geriatr Psychiatry Neurol. 2005 Dec; 18(4):228-33. . View in PubMed
  • Earlier Alzheimer onset in Latino persons: ethnic difference vs selection bias Arch Neurol. 2005 Nov; 62(11):1786-7. . View in PubMed
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