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Kathie Louise Eagleson, PhD
Associate Professor of Research Pediatrics
CHL 4650 Sunset Blvd Off Campus Los Angeles
+1 323 361 7564


Distinct intracellular signaling mediates C-MET regulation of dendritic growth and synaptogenesis. Dev Neurobiol. 2016 Oct; 76(10):1160-81. View in: PubMed

The Pleiotropic MET Receptor Network: Circuit Development and the Neural-Medical Interface of Autism. Biol Psychiatry. 2016 Sep 15. View in: PubMed

Hepatocyte Growth Factor Modulates MET Receptor Tyrosine Kinase and ß-Catenin Functional Interactions to Enhance Synapse Formation. eNeuro. 2016 Jul-Aug; 3(4). View in: PubMed

Receptor Tyrosine Kinase MET Interactome and Neurodevelopmental Disorder Partners at the Developing Synapse. Biol Psychiatry. 2016 Feb 26. View in: PubMed

Positive regulation of neocortical synapse formation by the Plexin-D1 receptor. Brain Res. 2015 Aug 7; 1616:157-65. View in: PubMed

Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampus. J Comp Neurol. 2013 Oct 1; 521(14):3241-59. View in: PubMed

A new synaptic player leading to autism risk: Met receptor tyrosine kinase. J Neurodev Disord. 2011 Sep; 3(3):282-92. View in: PubMed

The autism risk genes MET and PLAUR differentially impact cortical development. Autism Res. 2011 Feb; 4(1):68-83. View in: PubMed

Evidence of cell-nonautonomous changes in dendrite and dendritic spine morphology in the met-signaling-deficient mouse forebrain. J Comp Neurol. 2010 Nov 1; 518(21):4463-78. View in: PubMed

Genetic disruption of the autism spectrum disorder risk gene PLAUR induces GABAA receptor subunit changes. Neuroscience. 2010 Jul 14; 168(3):797-810. View in: PubMed

Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain. Neural Dev. 2010; 5:32. View in: PubMed

Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrain. J Comp Neurol. 2009 Apr 10; 513(5):511-31. View in: PubMed

Disruption of Foxg1 expression by knock-in of cre recombinase: effects on the development of the mouse telencephalon. Neuroscience. 2007 Aug 24; 148(2):385-99. View in: PubMed

Region- and age-specific deficits in gamma-aminobutyric acidergic neuron development in the telencephalon of the uPAR(-/-) mouse. J Comp Neurol. 2005 Sep 5; 489(4):449-66. View in: PubMed

Regulation of neocortical interneuron development and the implications for neurodevelopmental disorders. Trends Neurosci. 2004 Jul; 27(7):400-6. View in: PubMed

Distinct domains of the limbic system-associated membrane protein (LAMP) mediate discrete effects on neurite outgrowth. Mol Cell Neurosci. 2003 Nov; 24(3):725-40. View in: PubMed

Regional differences in neurotrophin availability regulate selective expression of VGF in the developing limbic cortex. J Neurosci. 2001 Dec 1; 21(23):9315-24. View in: PubMed

Regionalization of the cerebral cortex: developmental mechanisms and models. Novartis Found Symp. 2000; 228:173-81; discussion 181-7. View in: PubMed

Complex signaling responsible for molecular regionalization of the cerebral cortex. Cereb Cortex. 1999 Sep; 9(6):562-8. View in: PubMed

The role of ErbB receptor signaling in cell fate decisions by cortical progenitors: evidence for a biased, lineage-based responsiveness to different ligands. Mol Cell Neurosci. 1998 Dec; 12(6):349-62. View in: PubMed

Identification of a survival-promoting peptide in medium conditioned by oxidatively stressed cell lines of nervous system origin. J Neurosci. 1998 Sep 15; 18(18):7047-60. View in: PubMed

Mechanisms specifying area fate in cortex include cell-cycle-dependent decisions and the capacity of progenitors to express phenotype memory. Development. 1997 Apr; 124(8):1623-30. View in: PubMed

Patterning and specification of the cerebral cortex. Annu Rev Neurosci. 1997; 20:1-24. View in: PubMed

Signaling pathways that regulate specification of neurons in developing cerebral cortex. Dev Neurosci. 1997; 19(1):6-8. View in: PubMed

Complementary distribution of collagen type IV and the epidermal growth factor receptor in the rat embryonic telencephalon. Cereb Cortex. 1996 May-Jun; 6(3):540-9. View in: PubMed

Environmental signals influence expression of a cortical areal phenotype in vitro independent of effects on progenitor cell proliferation. Dev Biol. 1996 Apr 10; 175(1):184-90. View in: PubMed

Molecular contributions to cerebral cortical specification. Ciba Found Symp. 1995; 193:200-13; discussion 251-7. View in: PubMed

Rescue of both rapidly and slowly degenerating neurons in the dorsal lateral geniculate nucleus of adult rats by a cortically derived neuron survival factor. Exp Neurol. 1992 May; 116(2):156-62. View in: PubMed

Different populations of dorsal lateral geniculate nucleus neurons have concentration-specific requirements for a cortically derived neuron survival factor. Exp Neurol. 1990 Dec; 110(3):284-90. View in: PubMed

Influence of TRH and TRH analogues RGH-2202 and DN-1417 on cultured ventral spinal cord neurons. Ann N Y Acad Sci. 1989; 553:325-36. View in: PubMed

Motoneurone survival requirements during development: the change from immature astrocyte dependence to myotube dependence. Brain Res. 1986 Oct; 394(2):161-72. View in: PubMed

Motoneurone survival is induced by immature astrocytes from developing avian spinal cord. Brain Res. 1985 Jan; 349(1-2):95-104. View in: PubMed

Motor neuron survival and neuritic extension from spinal cord explants induced by factors released from denervated muscle. Brain Res. 1984 Jan 16; 291(1):19-28. View in: PubMed

Survival of purified motor neurones in vitro: effects of skeletal muscle-conditioned medium. Neurosci Lett. 1983 Jul 29; 38(2):187-92. View in: PubMed

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