Faculty

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Laila Ingrid Muderspach, MD
Chair and Associate Professor of The Department of Obstetrics & Gynecology
Obstetrics & Gynecology
IRD 220 Off Campus Los Angeles
+1 323 226 3416

Overview

Dr. Muderspach has been committed to improving women’s health throughout her career. Her clinical expertise is in the diagnosis, medical and surgical treatment of gynecologic malignancies. She believes in treating the “whole person” with respect, compassion and access to state of the art medicine and surgery. Her training at USC and UCLA, along with her vast clinical experience, have uniquely qualified her for her present position as the chair in the Department of Obstetrics and Gynecology as well as the residency program director. She has won numerous awards for her work teaching and caring for patients in Ob/Gyn. She is recognized in “Best Doctors” as selected by her peers.

Awards

American Cancer Society : Clinical Fellow, 1989-1990

The American College of Obstetricians and Gynecologists: National Faculty Award, 2007

Los Angeles: Top Doctors , 2015-2016

C.A.R.E.S. : Woman of the Year in Medicine, 2000

LAC + USC: Women’s Choice Award, America’s Best Hospitals, Patient Safety, 2016

Pasadena Magazine: Top Doctors, 2013-2015

Best Doctors

Association of Professors of Gynecology and Obstetrics: Excellent Teaching Award, 1998

Alpha Omega Alpha Honor Medical Society

Mackenzie Foundation Scholarship

American Medical Women's Associatoin: Janet M. Glasgow Memorial Achievement Citation, 1985

CREOG: Teaching Award, 2006

Lester T. Hibbard : Faculty Teaching Award, 2004-2005

Publications

Matsuo K, Machida H, Shoupe D, Melamed A, Muderspach LI, Roman LD, Wright JD. Ovarian Conservation and Overall Survival in Young Women With Early-Stage Cervical Cancer. Obstet Gynecol. 2016 Dec 02. View in: PubMed

Matsuo K, Machida H, Shoupe D, Melamed A, Muderspach LI, Roman LD, Wright JD. Ovarian Conservation and Overall Survival in Young Women With Early-Stage Low-Grade Endometrial Cancer. Obstet Gynecol. 2016 Sep 5. View in: PubMed

Matsuo K, Moeini A, Cahoon SS, Machida H, Ciccone MA, Grubbs BH, Muderspach LI. Weight Change Pattern and Survival Outcome of Women with Endometrial Cancer. Ann Surg Oncol. 2016 Apr 25. View in: PubMed

Ramzan AA, Garcia-Sayre J, Hom MS, Graham KA, Carey JN, Muderspach LI, Matsuo K. Relative Morbidity and Mortality of Panniculectomy-Combined Surgical Staging in Endometrial Cancer. Int J Gynecol Cancer. 2015 Aug 12. View in: PubMed

Matsuo K, Gualtieri MR, Cahoon SS, Jung CE, Paulson RJ, Shoupe D, Muderspach LI, Wakatsuki A, Wright JD, Roman LD. Surgical menopause and increased risk of nonalcoholic fatty liver disease in endometrial cancer. Menopause. 2015 Jul 13. View in: PubMed

Stany MP, Stone PJ, Felix JC, Amezcua CA, Groshen S, Ye W, Kyser KL, Howard RS, Zahn CM, Muderspach LI, Lentz SE, Chernofsky MR. Lymph Node Micrometastases in Early-Stage Cervical Cancer are Not Predictive of Survival. Int J Gynecol Pathol. 2015 Jul; 34(4):379-84. View in: PubMed

Matsuo K, Opper NR, Ciccone MA, Garcia J, Tierney KE, Baba T, Muderspach LI, Roman LD. Time interval between endometrial biopsy and surgical staging for type I endometrial cancer: association between tumor characteristics and survival outcome. Obstet Gynecol. 2015 Feb; 125(2):424-33. View in: PubMed

Matsuo K, Cahoon SS, Gualtieri M, Scannell CA, Jung CE, Takano T, Paulson RJ, Muderspach LI, Roman LD. Significance of adenomyosis on tumor progression and survival outcome of endometrial cancer. Ann Surg Oncol. 2014 Dec; 21(13):4246-55. View in: PubMed

Chandavarkar U, Kuperman JM, Muderspach LI, Opper N, Felix JC, Roman L. Endometrial echo complex thickness in postmenopausal endometrial cancer. Gynecol Oncol. 2013 Oct; 131(1):109-12. View in: PubMed

Matsuo K, Yessaian AA, Lin YG, Pham HQ, Muderspach LI, Liebman HA, Morrow CP, Roman LD. Predictive model of venous thromboembolism in endometrial cancer. Gynecol Oncol. 2013 Mar; 128(3):544-51. View in: PubMed

Sonoda LA, Rosenheck RE, Tierney K, Muderspach LI, Palmer SL, Senikowich M, Lin YG. Novel application of a fecal management system for vaginal use in radiotherapy-associated rectovaginal fistula. Palliat Med. 2013 Jan; 27(1):91-3. View in: PubMed

Garcia AA, Yessaian A, Pham H, Facio G, Muderspach L, Roman L. Phase II Study of Gemcitabine and Docetaxel in Recurrent Platinum Resistant Ovarian Cancer. Cancer Invest. 2012 May; 30(4):295-9. View in: PubMed

Hong A, Mullin PM, Al-Marayati L, Peyre SE, Muderspach L, Macdonald H, Ouzounian JG, Miller DA, Opper N, Lee RH. A low-fidelity total abdominal hysterectomy teaching model for obstetrics and gynecology residents. Simul Healthc. 2012 Apr; 7(2):123-6. View in: PubMed

D'Orazio LM, Meyerowitz BE, Stone PJ, Felix J, Muderspach LI. Psychosocial adjustment among low-income Latina cervical cancer patients. J Psychosoc Oncol. 2011 Sep-Oct; 29(5):515-33. View in: PubMed

Klobocista M, Yessaian AA, Morrow CP, Muderspach L, Pham H, Lin YG, Sposto R, Roman L. The role of adjuvant chemotherapy in early-stage high-grade uterine leiomyosarcoma: A retrospective review. J Clin Oncol. 2011 May 20; 29(15_suppl):e15500. View in: PubMed

Ell K, Vourlekis B, Xie B, Nedjat-Haiem FR, Lee PJ, Muderspach L, Russell C, Palinkas LA. Cancer treatment adherence among low-income women with breast or gynecologic cancer: a randomized controlled trial of patient navigation. Cancer. 2009 Oct 1; 115(19):4606-15. View in: PubMed

Konecny GE, Santos L, Winterhoff B, Hatmal M, Keeney GL, Mariani A, Jones M, Neuper C, Thomas B, Muderspach L, Riehle D, Wang HJ, Dowdy S, Podratz KC, Press MF. HER2 gene amplification and EGFR expression in a large cohort of surgically staged patients with nonendometrioid (type II) endometrial cancer. Br J Cancer. 2009 Jan 13; 100(1):89-95. View in: PubMed

Urwitz-Lane RS, Lee RH, Peyre S, Rahman S, Kwok L, Muderspach L. Impact of laparoscopic experience on performance on laparoscopic training drills among obstetrics and gynecology residents: a pilot study. J Minim Invasive Gynecol. 2009 Jan-Feb; 16(1):72-5. View in: PubMed

Massad LS, Evans CT, D'Souza G, Darragh T, Minkoff H, Henry D, Goparaju L, Muderspach LI, Watts DH. High-grade cervical disease in adolescents with HIV. J Low Genit Tract Dis. 2008 Jul; 12(3):199-203. View in: PubMed

Watts DH, Park JG, Cohn SE, Yu S, Hitti J, Stek A, Clax PA, Muderspach L, Lertora JJ. Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093. Contraception. 2008 Feb; 77(2):84-90. View in: PubMed

Stehman FB, Ali S, Keys HM, Muderspach LI, Chafe WE, Gallup DG, Walker JL, Gersell D. Radiation therapy with or without weekly cisplatin for bulky stage 1B cervical carcinoma: follow-up of a Gynecologic Oncology Group trial. Am J Obstet Gynecol. 2007 Nov; 197(5):503. e1-6. View in: PubMed

Brinkman JA, Hughes SH, Stone P, Caffrey AS, Muderspach LI, Roman LD, Weber JS, Kast WM. Therapeutic vaccination for HPV induced cervical cancers. Dis Markers. 2007; 23(4):337-52. View in: PubMed

Lowe MP, Bahador A, Muderspach LI, Burnett A, Santos L, Caffrey A, Roman LD, Morrow CP. Feasibility of laparoscopic extraperitoneal surgical staging for locally advanced cervical carcinoma in a gynecologic oncology fellowship training program. J Minim Invasive Gynecol. 2006 Sep-Oct; 13(5):391-7. View in: PubMed

Rotman M, Sedlis A, Piedmonte MR, Bundy B, Lentz SS, Muderspach LI, Zaino RJ. A phase III randomized trial of postoperative pelvic irradiation in Stage IB cervical carcinoma with poor prognostic features: follow-up of a gynecologic oncology group study. Int J Radiat Oncol Biol Phys. 2006 May 1; 65(1):169-76. View in: PubMed

Chernofsky MR, Felix JC, Muderspach LI, Morrow CP, Ye W, Groshen SG, Roman LD. Influence of quantity of lymph vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix. Gynecol Oncol. 2006 Feb; 100(2):288-93. View in: PubMed

Cremer M, Jamshidi RM, Muderspach L, Tsao-Wei D, Felix JC, Blumenthal PD. Digital camera assessment for detection of cervical intraepithelial neoplasia in rural El Salvador. Int J Gynaecol Obstet. 2005 Oct; 91(1):42-6. View in: PubMed

Ell K, Sanchez K, Vourlekis B, Lee PJ, Dwight-Johnson M, Lagomasino I, Muderspach L, Russell C. Depression, correlates of depression, and receipt of depression care among low-income women with breast or gynecologic cancer. J Clin Oncol. 2005 May 1; 23(13):3052-60. View in: PubMed

Garcia AA, Roman L, Muderspach L, O'meara A, Facio G, Edwards S, Burnett A. Phase I clinical trial of topotecan and pegylated liposomal doxorubicin. Cancer Invest. 2005; 23(8):665-70. View in: PubMed

Lentz SE, Muderspach LI, Felix JC, Ye W, Groshen S, Amezcua CA. Identification of micrometastases in histologically negative lymph nodes of early-stage cervical cancer patients. Obstet Gynecol. 2004 Jun; 103(6):1204-10. View in: PubMed

Garcia F, Petry KU, Muderspach L, Gold MA, Braly P, Crum CP, Magill M, Silverman M, Urban RG, Hedley ML, Beach KJ. ZYC101a for treatment of high-grade cervical intraepithelial neoplasia: a randomized controlled trial. Obstet Gynecol. 2004 Feb; 103(2):317-26. View in: PubMed

Sheets EE, Urban RG, Crum CP, Hedley ML, Politch JA, Gold MA, Muderspach LI, Cole GA, Crowley-Nowick PA. Immunotherapy of human cervical high-grade cervical intraepithelial neoplasia with microparticle-delivered human papillomavirus 16 E7 plasmid DNA. Am J Obstet Gynecol. 2003 Apr; 188(4):916-26. View in: PubMed

Ell K, Vourlekis B, Muderspach L, Nissly J, Padgett D, Pineda D, Sarabia O, Lee PJ. Abnormal cervical screen follow-up among low-income Latinas: Project SAFe. J Womens Health Gend Based Med. 2002 Sep; 11(7):639-51. View in: PubMed

Silverberg MJ, Ahdieh L, Munoz A, Anastos K, Burk RD, Cu-Uvin S, Duerr A, Greenblatt RM, Klein RS, Massad S, Minkoff H, Muderspach L, Palefsky J, Piessens E, Schuman P, Watts H, Shah KV. The impact of HIV infection and immunodeficiency on human papillomavirus type 6 or 11 infection and on genital warts. Sex Transm Dis. 2002 Aug; 29(8):427-35. View in: PubMed

Minkoff H, Ahdieh L, Massad LS, Anastos K, Watts DH, Melnick S, Muderspach L, Burk R, Palefsky J. The effect of highly active antiretroviral therapy on cervical cytologic changes associated with oncogenic HPV among HIV-infected women. AIDS. 2001 Nov 9; 15(16):2157-64. View in: PubMed

Safra T, Groshen S, Jeffers S, Tsao-Wei DD, Zhou L, Muderspach L, Roman L, Morrow CP, Burnett A, Muggia FM. Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: analysis of toxicities and predictors of outcome. Cancer. 2001 Jan 1; 91(1):90-100. View in: PubMed

Massad SL, Kirstein L, Darragh T, Bitterman P, Sidawy M, Muderspach L, Abulafia O, Salzer E, Watts H, Melnick S. Interrater Variability in Diagnosis of Cervical Biopsies from Women with HIV-1: Results from the Women's Interagency HIV Study. J Low Genit Tract Dis. 2000 Oct; 4(4):190-4. View in: PubMed

Muderspach L, Wilczynski S, Roman L, Bade L, Felix J, Small LA, Kast WM, Fascio G, Marty V, Weber J. A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. Clin Cancer Res. 2000 Sep; 6(9):3406-16. View in: PubMed

Israel VP, Garcia AA, Roman L, Muderspach L, Burnett A, Jeffers S, Muggia FM. Phase II study of liposomal doxorubicin in advanced gynecologic cancers. Gynecol Oncol. 2000 Aug; 78(2):143-7. View in: PubMed

Harlow SD, Schuman P, Cohen M, Ohmit SE, Cu-Uvin S, Lin X, Anastos K, Burns D, Greenblatt R, Minkoff H, Muderspach L, Rompalo A, Warren D, Young MA, Klein RS. Effect of HIV infection on menstrual cycle length. J Acquir Immune Defic Syndr. 2000 May 1; 24(1):68-75. View in: PubMed

Kovacs A, Chan LS, Chen ZC, Meyer WA, Muderspach L, Young M, Anastos K, Levine AM. HIV-1 RNA in plasma and genital tract secretions in women infected with HIV-1. J Acquir Immune Defic Syndr. 1999 Oct 1; 22(2):124-31. View in: PubMed

Sorvillo F, Kovacs A, Kerndt P, Stek A, Muderspach L, Sanchez-Keeland L. Risk factors for trichomoniasis among women with human immunodeficiency virus (HIV) infection at a public clinic in Los Angeles County, California: implications for HIV prevention. Am J Trop Med Hyg. 1998 Apr; 58(4):495-500. View in: PubMed

Muggia FM, Jeffers S, Muderspach L, Roman L, Rosales R, Groshen S, Safra T, Morrow CP. Phase I/II study of intraperitoneal floxuridine and platinums (cisplatin and/or carboplatin). Gynecol Oncol. 1997 Aug; 66(2):290-4. View in: PubMed

Muggia FM, Hainsworth JD, Jeffers S, Miller P, Groshen S, Tan M, Roman L, Uziely B, Muderspach L, Garcia A, Burnett A, Greco FA, Morrow CP, Paradiso LJ, Liang LJ. Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation. J Clin Oncol. 1997 Mar; 15(3):987-93. View in: PubMed

Muderspach L, Muggia FM, Conti PS. Second-look laparotomy for stage III epithelial ovarian cancer: rationale and current issues. Cancer Treat Rev. 1996 Nov; 21(6):499-511. View in: PubMed

Casey AC, Farias-Eisner R, Pisani AL, Cirisano FD, Kim YB, Muderspach L, Futoran R, Leuchter RS, Lagasse LD, Karlan BY. What is the role of reassessment laparoscopy in the management of gynecologic cancers in 1995? Gynecol Oncol. 1996 Mar; 60(3):454-61. View in: PubMed

Formenti SC, Meyerowitz BE, Ell K, Muderspach L, Groshen S, Leedham B, Klement V, Morrow PC. Inadequate adherence to radiotherapy in Latina immigrants with carcinoma of the cervix. Potential impact on disease free survival. Cancer. 1995 Mar 1; 75(5):1135-40. View in: PubMed

Uziely B, Groshen S, Jeffers S, Morris M, Russell C, Roman L, Muderspach L, Muggia F. Paclitaxel (Taxol) in heavily pretreated ovarian cancer: antitumor activity and complications. Ann Oncol. 1994 Nov; 5(9):827-33. View in: PubMed

Muggia FM, Muderspach L. Platinum compounds in cervical and endometrial cancers: focus on carboplatin. Semin Oncol. 1994 Apr; 21(2 Suppl 2):35-41; quiz 42, 58. View in: PubMed

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