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Louis Dubeau, MD, PhD
Professor of Pathology
NOR 6338 Health Sciences Campus Los Angeles
+1 323 865 0720


For many years, Dr. Dubeau has been a leading practitioner, educator and researcher in the field of ovarian cancer biology. A native of Canada, Dr. Dubeau first came to USC as a post-doctoral fellow at the Norris Comprehensive Cancer Center. During his time at USC, Dr. Dubeau has achieved the status of full professor, become director of the Molecular Diagnostics Laboratory at USC/Norris Comprehensive Cancer Center published numerous peer-reviewed articles for medical journals and lectured at medical conferences and seminars across the United States, Canada, United Kingdom, Hungary, Turkey and Greece. Dr. Dubeau is a renowned researcher and has been awarded over fourteen million dollars in research grants, many dealing with either ovarian cancer biology and genetics or with environmental issues such as exposure to and effects of air pollution. A devoted educator, Dr. Dubeau has mentored over fifty students, either as a member of their PhD advisory committee or by training doctoral and graduate students. Dr. Dubeau also has found time throughout his career to give lectures on health related subjects to area public school students.


Lee AS, Brandhorst S, Rangel DF, Navarrete G, Cohen P, Longo VD, Chen J, Groshen S, Morgan TE, Dubeau L. Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice. Sci Rep. 2017 Feb 01; 7:40919. View in: PubMed

Kiechl S, Schramek D, Widschwendter M, Fourkala EO, Zaikin A, Jones A, Jaeger B, Rack B, Janni W, Scholz C, Willeit J, Weger S, Mayr A, Teschendorff A, Rosenthal A, Fraser L, Philpott S, Dubeau L, Keshtgar M, Roylance R, Jacobs IJ, Menon U, Schett G, Penninger JM. Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer. Oncotarget. 2016 Dec 18. View in: PubMed

Shen J, Yao L, Lin YG, DeMayo FJ, Lydon JP, Dubeau L, Lee AS. Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development. Oncotarget. 2016 Mar 22; 7(12):14885-97. View in: PubMed

Bartlett TE, Chindera K, McDermott J, Breeze CE, Cooke WR, Jones A, Reisel D, Karegodar ST, Arora R, Beck S, Menon U, Dubeau L, Widschwendter M. Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution. Nat Commun. 2016; 7:11620. View in: PubMed

Widschwendter M, Burnell M, Fraser L, Rosenthal AN, Philpott S, Reisel D, Dubeau L, Cline M, Pan Y, Yi PC, Gareth Evans D, Jacobs IJ, Menon U, Wood CE, Dougall WC. Osteoprotegerin (OPG), The Endogenous Inhibitor of Receptor Activator of NF-?B Ligand (RANKL), is Dysregulated in BRCA Mutation Carriers. EBioMedicine. 2015 Oct; 2(10):1331-9. View in: PubMed

Liu Y, Yen HY, Austria T, Pettersson J, Peti-Peterdi J, Maxson R, Widschwendter M, Dubeau L. A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State. EBioMedicine. 2015 Oct; 2(10):1318-30. View in: PubMed

Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G, Dubeau L, Yap LP, Park R, Vinciguerra M, Di Biase S, Mirzaei H, Mirisola MG, Childress P, Ji L, Groshen S, Penna F, Odetti P, Perin L, Conti PS, Ikeno Y, Kennedy BK, Cohen P, Morgan TE, Dorff TB, Longo VD. A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan. Cell Metab. 2015 Jul 7; 22(1):86-99. View in: PubMed

Dubeau L. Pathogenesis of serous, extra-uterine Müllerian epithelial cancer and therapeutic implications. Transl Cancer Res. 2015 Feb; 4(1):3-13. View in: PubMed

Liu Y, Pike MC, Wu N, Lin YG, Mucowski S, Punj V, Tang Y, Yen HY, Stanczyk FZ, Enbom E, Austria T, Widschwendter M, Maxson R, Dubeau L. Brca1 Mutations Enhance Mouse Reproductive Functions by Increasing Responsiveness to Male-Derived Scent. PLoS One. 2015; 10(10):e0139013. View in: PubMed

Teschendorff AE, Lee SH, Jones A, Fiegl H, Kalwa M, Wagner W, Chindera K, Evans I, Dubeau L, Orjalo A, Horlings HM, Niederreiter L, Kaser A, Yang W, Goode EL, Fridley BL, Jenner RG, Berns EM, Wik E, Salvesen HB, Wisman GB, van der Zee AG, Davidson B, Trope CG, Lambrechts S, Vergote I, Calvert H, Jacobs IJ, Widschwendter M. HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer. Genome Med. 2015; 7(1):108. View in: PubMed

Palian BM, Rohira AD, Johnson SA, He L, Zheng N, Dubeau L, Stiles BL, Johnson DL. Maf1 Is a Novel Target of PTEN and PI3K Signaling That Negatively Regulates Oncogenesis and Lipid Metabolism. PLoS Genet. 2014 Dec; 10(12):e1004789. View in: PubMed

Cho HY, Wang W, Jhaveri N, Lee DJ, Sharma N, Dubeau L, Schönthal AH, Hofman FM, Chen TC. NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas. Mol Cancer Ther. 2014 Aug; 13(8):2004-17. View in: PubMed

Dubeau L, Drapkin R. Coming into focus: the nonovarian origins of ovarian cancer. Ann Oncol. 2013 Nov; 24 Suppl 8:viii28-viii35. View in: PubMed

Widschwendter M, Rosenthal AN, Philpott S, Rizzuto I, Fraser L, Hayward J, Intermaggio MP, Edlund CK, Ramus SJ, Gayther SA, Dubeau L, Fourkala EO, Zaikin A, Menon U, Jacobs IJ. The sex hormone system in carriers of BRCA1/2 mutations: a case-control study. Lancet Oncol. 2013 Nov; 14(12):1226-32. View in: PubMed

Matsuo K, Gray MJ, Yang DY, Srivastava SA, Tripathi PB, Sonoda LA, Yoo EJ, Dubeau L, Lee AS, Lin YG. The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival. Gynecol Oncol. 2013 Mar; 128(3):552-9. View in: PubMed

Yu VM, Marion CM, Austria TM, Yeh J, Schönthal AH, Dubeau L. Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. Int J Cancer. 2012 Jun 1; 130(11):2495-504. View in: PubMed

Yen HY, Gabet Y, Liu Y, Martin A, Wu NL, Pike MC, Frenkel B, Maxson R, Dubeau L. Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs. Lab Invest. 2012 Jun; 92(6):802-11. View in: PubMed

Lagos-Jaramillo VI, Press MF, Ricker CN, Dubeau L, Mai PL, Weitzel JN. Pathological characteristics of BRCA-associated breast cancers in Hispanics. Breast Cancer Res Treat. 2011 Nov; 130(1):281-9. View in: PubMed

Campan M, Moffitt M, Houshdaran S, Shen H, Widschwendter M, Daxenbichler G, Long T, Marth C, Laird-Offringa IA, Press MF, Dubeau L, Siegmund KD, Wu AH, Groshen S, Chandavarkar U, Roman LD, Berchuck A, Pearce CL, Laird PW. Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. PLoS One. 2011; 6(12):e28141. View in: PubMed

Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS. Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis. Cell Death Differ. 2010 Mar; 17(3):488-98. View in: PubMed

Hong H, Yen HY, Brockmeyer A, Liu Y, Chodankar R, Pike MC, Stanczyk FZ, Maxson R, Dubeau L. Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer. Cancer Res. 2010 Jan 1; 70(1):221-8. View in: PubMed

Widschwendter M, Apostolidou S, Jones AA, Fourkala EO, Arora R, Pearce CL, Frasco MA, Ayhan A, Zikan M, Cibula D, Iyibozkurt CA, Yavuz E, Hauser-Kronberger C, Dubeau L, Menon U, Jacobs IJ. HOXA methylation in normal endometrium from premenopausal women is associated with the presence of ovarian cancer: a proof of principle study. Int J Cancer. 2009 Nov 1; 125(9):2214-8. View in: PubMed

Shao C, Lacey M, Dubeau L, Ehrlich M. Hemimethylation footprints of DNA demethylation in cancer. Epigenetics. 2009 Apr 1; 4(3):165-75. View in: PubMed

Dubeau L. The cell of origin of ovarian epithelial tumours. Lancet Oncol. 2008 Dec; 9(12):1191-7. View in: PubMed

Yoo CB, Chuang JC, Byun HM, Egger G, Yang AS, Dubeau L, Long T, Laird PW, Marquez VE, Jones PA. Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prev Res (Phila). 2008 Sep; 1(4):233-40. View in: PubMed

Johnson SA, Dubeau L, Johnson DL. Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation. J Biol Chem. 2008 Jul 11; 283(28):19184-91. View in: PubMed

Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS. Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Res. 2008 Jan 15; 68(2):498-505. View in: PubMed

Dubeau L. BRCA1-induced ovarian oncogenesis. Adv Exp Med Biol. 2008; 622:89-97. View in: PubMed

Yu J, Roy D, Brockmeyer AD, Dubeau L. Increased chromosomal stability in cultures of ovarian tumours of low malignant potential compared to cystadenomas. Br J Cancer. 2007 Jun 18; 96(12):1908-13. View in: PubMed

Shelbourne PF, Keller-McGandy C, Bi WL, Yoon SR, Dubeau L, Veitch NJ, Vonsattel JP, Wexler NS. Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain. Hum Mol Genet. 2007 May 15; 16(10):1133-42. View in: PubMed

Kumar SR, Masood R, Spannuth WA, Singh J, Scehnet J, Kleiber G, Jennings N, Deavers M, Krasnoperov V, Dubeau L, Weaver FA, Sood AK, Gill PS. The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome. Br J Cancer. 2007 Apr 10; 96(7):1083-91. View in: PubMed

Li YF, Gauderman WJ, Avol E, Dubeau L, Gilliland FD. Associations of tumor necrosis factor G-308A with childhood asthma and wheezing. Am J Respir Crit Care Med. 2006 May 1; 173(9):970-6. View in: PubMed

Ehrlich M, Woods CB, Yu MC, Dubeau L, Yang F, Campan M, Weisenberger DJ, Long T, Youn B, Fiala ES, Laird PW. Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors. Oncogene. 2006 Apr 27; 25(18):2636-45. View in: PubMed

Wenten M, Berhane K, Rappaport EB, Avol E, Tsai WW, Gauderman WJ, McConnell R, Dubeau L, Gilliland FD. TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absences. Am J Respir Crit Care Med. 2005 Dec 15; 172(12):1563-8. View in: PubMed

Li YF, Tsao YH, Gauderman WJ, Conti DV, Avol E, Dubeau L, Gilliland FD. Intercellular adhesion molecule-1 and childhood asthma. Hum Genet. 2005 Sep; 117(5):476-84. View in: PubMed

Grunau C, Sanchez C, Ehrlich M, van der Bruggen P, Hindermann W, Rodriguez C, Krieger S, Dubeau L, Fiala E, De Sario A. Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer. Genes Chromosomes Cancer. 2005 May; 43(1):11-24. View in: PubMed

Nishiyama R, Qi L, Tsumagari K, Weissbecker K, Dubeau L, Champagne M, Sikka S, Nagai H, Ehrlich M. A DNA repeat, NBL2, is hypermethylated in some cancers but hypomethylated in others. Cancer Biol Ther. 2005 Apr; 4(4):440-8. View in: PubMed

Chodankar R, Kwang S, Sangiorgi F, Hong H, Yen HY, Deng C, Pike MC, Shuler CF, Maxson R, Dubeau L. Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells. Curr Biol. 2005 Mar 29; 15(6):561-5. View in: PubMed

Dong D, Dubeau L, Bading J, Nguyen K, Luna M, Yu H, Gazit-Bornstein G, Gordon EM, Gomer C, Hall FL, Gambhir SS, Lee AS. Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors. Hum Gene Ther. 2004 Jun; 15(6):553-61. View in: PubMed

Nouriani M, Bahador A, Berek JS, Cheng JP, Chi DS, Cliby WA, Del Priore G, Dodson MK, Duggan BD, Gershenson DM, Lentz SE, Penson RT, Robinson WR, Rodriguez M, Roman LD, Yu MC, Zempolich K, Dubeau L. Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy. Clin Cancer Res. 2004 Apr 15; 10(8):2681-6. View in: PubMed

Blumenthal M, Kardosh A, Dubeau L, Borok Z, Schönthal AH. Suppression of the transformed phenotype and induction of differentiation-like characteristics in cultured ovarian tumor cells by chronic treatment with progesterone. Mol Carcinog. 2003 Dec; 38(4):160-9. View in: PubMed

Velicescu M, Yu J, Herbert BS, Shay JW, Granada E, Dubeau L. Aneuploidy and telomere attrition are independent determinants of crisis in SV40-transformed epithelial cells. Cancer Res. 2003 Sep 15; 63(18):5813-20. View in: PubMed

Johnson SA, Dubeau L, White RJ, Johnson DL. The TATA-binding protein as a regulator of cellular transformation. Cell Cycle. 2003 Sep-Oct; 2(5):442-4. View in: PubMed

Yoon SR, Dubeau L, de Young M, Wexler NS, Arnheim N. Huntington disease expansion mutations in humans can occur before meiosis is completed. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8834-8. View in: PubMed

Johnson SA, Dubeau L, Kawalek M, Dervan A, Schönthal AH, Dang CV, Johnson DL. Increased expression of TATA-binding protein, the central transcription factor, can contribute to oncogenesis. Mol Cell Biol. 2003 May; 23(9):3043-51. View in: PubMed

Reddy RK, Dubeau L, Kleiner H, Parr T, Nichols P, Ko B, Dong D, Ko H, Mao C, DiGiovanni J, Lee AS. Cancer-inducible transgene expression by the Grp94 promoter: spontaneous activation in tumors of various origins and cancer-associated macrophages. Cancer Res. 2002 Dec 15; 62(24):7207-12. View in: PubMed

Velicescu M, Dubeau L. p53: a key player in the telomere dynamics. Cancer Biol Ther. 2002 Sep-Oct; 1(5):518-9. View in: PubMed

Gilliland FD, Gauderman WJ, Vora H, Rappaport E, Dubeau L. Effects of glutathione-S-transferase M1, T1, and P1 on childhood lung function growth. Am J Respir Crit Care Med. 2002 Sep 1; 166(5):710-6. View in: PubMed

Gilliland FD, Li YF, Dubeau L, Berhane K, Avol E, McConnell R, Gauderman WJ, Peters JM. Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med. 2002 Aug 15; 166(4):457-63. View in: PubMed

Gilliland FD, Rappaport EB, Berhane K, Islam T, Dubeau L, Gauderman WJ, McConnell R. Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children. Am J Respir Crit Care Med. 2002 Aug 1; 166(3):346-51. View in: PubMed

Chen C, Petitclerc E, Zhou H, Brooks PC, Sun T, Yu MC, Zheng W, Dubeau L. Effect of reproductive hormones on ovarian epithelial tumors: II. Effect on angiogenic activity. Cancer Biol Ther. 2002 May-Jun; 1(3):307-12. View in: PubMed

Zhou H, Luo MP, Schönthal AH, Pike MC, Stallcup MR, Blumenthal M, Zheng W, Dubeau L. Effect of reproductive hormones on ovarian epithelial tumors: I. Effect on cell cycle activity. Cancer Biol Ther. 2002 May-Jun; 1(3):300-6. View in: PubMed

Yu J, Dubeau L. Telomerase and malignant transformation. Cancer Treat Res. 2002; 107:213-28. View in: PubMed

London SJ, Xia J, Lehman TA, Yang JH, Granada E, Chunhong L, Dubeau L, Li T, David-Beabes GL, Li Y. Collection of buccal cell DNA in seventh-grade children using water and a toothbrush. Cancer Epidemiol Biomarkers Prev. 2001 Nov; 10(11):1227-30. View in: PubMed

Rodriguez M, Dubeau L. Ovarian tumor development: insights from ovarian embryogenesis. Eur J Gynaecol Oncol. 2001; 22(3):175-83. View in: PubMed

Bösze P, Bast RC, Berchuck A, Burke HB, Buller RE, Creasman WT, Dubeau L, Fox H, Geisler HE, Geisler JP, Henson DE, Rustin GJ, Vermorken JB, Wells M, Wilbanks GD. Conseusus statements on prognostic factors in epithelial ovarian carcinoma. Report of the Consensus Meeting organized by the European Society of Gynaecological Oncology, ESGO. Eur J Gynaecol Oncol. 2000; 21(5):513-26. View in: PubMed

Dubeau L. The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes? Gynecol Oncol. 1999 Mar; 72(3):437-42. View in: PubMed

Wan M, Sun T, Vyas R, Zheng J, Granada E, Dubeau L. Suppression of tumorigenicity in human ovarian cancer cell lines is controlled by a 2 cM fragment in chromosomal region 6q24-q25. Oncogene. 1999 Feb 25; 18(8):1545-51. View in: PubMed

Qu G, Dubeau L, Narayan A, Yu MC, Ehrlich M. Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential. Mutat Res. 1999 Jan 25; 423(1-2):91-101. View in: PubMed

McCluskey LL, Chen C, Delgadillo E, Felix JC, Muderspach LI, Dubeau L. Differences in p16 gene methylation and expression in benign and malignant ovarian tumors. Gynecol Oncol. 1999 Jan; 72(1):87-92. View in: PubMed

Duggan BD, Dubeau L. Genetics and biology of gynecologic cancer. Curr Opin Oncol. 1998 Sep; 10(5):439-46. View in: PubMed

Duggan BD, Wan M, Yu MC, Roman LD, Muderspach LI, Delgadillo E, Li WZ, Martin SE, Dubeau L. Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination. J Natl Cancer Inst. 1998 Feb 4; 90(3):238-42. View in: PubMed

Zempolich KA, Dubeau L. Telomerase and cancer management: silver bullet or fool's gold? Gynecol Oncol. 1998 Feb; 68(2):143-4. View in: PubMed

Luo MP, Gomperts B, Imren S, DeClerck YA, Ito M, Velicescu M, Felix JC, Dubeau L. Establishment of long-term in vitro cultures of human ovarian cystadenomas and LMP tumors and examination of their spectrum of expression of matrix-degrading proteinases. Gynecol Oncol. 1997 Dec; 67(3):277-84. View in: PubMed

McCluskey LL, Dubeau L. Biology of ovarian cancer. Curr Opin Oncol. 1997 Sep; 9(5):465-70. View in: PubMed

Wan M, Li WZ, Duggan BD, Felix JC, Zhao Y, Dubeau L. Telomerase activity in benign and malignant epithelial ovarian tumors. J Natl Cancer Inst. 1997 Mar 19; 89(6):437-41. View in: PubMed

Cheng P, Schmutte C, Cofer KF, Felix JC, Yu MC, Dubeau L. Alterations in DNA methylation are early, but not initial, events in ovarian tumorigenesis. Br J Cancer. 1997; 75(3):396-402. View in: PubMed

Wan M, Cofer KF, Dubeau L. WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer. Br J Cancer. 1996 Jun; 73(11):1398-400. View in: PubMed

Cheng PC, Gosewehr JA, Kim TM, Velicescu M, Wan M, Zheng J, Felix JC, Cofer KF, Luo P, Biela BH, Godorov G, Dubeau L. Potential role of the inactivated X chromosome in ovarian epithelial tumor development. J Natl Cancer Inst. 1996 Apr 17; 88(8):510-8. View in: PubMed

Bellacosa A, de Feo D, Godwin AK, Bell DW, Cheng JQ, Altomare DA, Wan M, Dubeau L, Scambia G, Masciullo V, Ferrandina G, Benedetti Panici P, Mancuso S, Neri G, Testa JR. Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int J Cancer. 1995 Aug 22; 64(4):280-5. View in: PubMed

Zheng J, Benedict WF, Xu HJ, Hu SX, Kim TM, Velicescu M, Wan M, Cofer KF, Dubeau L. Genetic disparity between morphologically benign cysts contiguous to ovarian carcinomas and solitary cystadenomas. J Natl Cancer Inst. 1995 Aug 2; 87(15):1146-53. View in: PubMed

Wan M, Zweizig S, Dablaing G, Zheng J, Velicescu M, Dubeau L. 3 distinct regions of chromosome-6 are targets of loss of heterozygosity in human ovarian carcinomas. Int J Oncol. 1994 Nov; 5(5):1043-8. View in: PubMed

Kim TM, Benedict WF, Xu HJ, Hu SX, Gosewehr J, Velicescu M, Yin E, Zheng J, D'Ablaing G, Dubeau L. Loss of heterozygosity on chromosome 13 is common only in the biologically more aggressive subtypes of ovarian epithelial tumors and is associated with normal retinoblastoma gene expression. Cancer Res. 1994 Feb 1; 54(3):605-9. View in: PubMed

Zheng J, Wan M, Zweizig S, Velicescu M, Yu MC, Dubeau L. Histologically benign or low-grade malignant tumors adjacent to high-grade ovarian carcinomas contain molecular characteristics of high-grade carcinomas. Cancer Res. 1993 Sep 15; 53(18):4138-42. View in: PubMed

Friedman R, Velicescu M, Dubeau L. Mutations in an alternatively spliced exon of h-ras are not associated with loss of heterozygosity on chromosome 11p15. 5 in ovarian tumorigenesis. Int J Oncol. 1992 Jul; 1(2):215-9. View in: PubMed

Zheng JP, Robinson WR, Ehlen T, Yu MC, Dubeau L. Distinction of low grade from high grade human ovarian carcinomas on the basis of losses of heterozygosity on chromosomes 3, 6, and 11 and HER-2/neu gene amplification. Cancer Res. 1991 Aug 1; 51(15):4045-51. View in: PubMed

Dubeau L, Velicescu M, Sherrod AE, Schreiber G, Holt G. Culture of human fetal ovarian epithelium in a chemically-defined, serum-free medium: a model for ovarian carcinogenesis. Anticancer Res. 1990 Sep-Oct; 10(5A):1233-40. View in: PubMed

Schreiber G, Dubeau L. C-myc proto-oncogene amplification detected by polymerase chain reaction in archival human ovarian carcinomas. Am J Pathol. 1990 Sep; 137(3):653-8. View in: PubMed

Allen LE, Dubeau L, Alvarez O, Jones PA. Rapid degradation of extracellular matrix proteins by normal human uroepithelial cells. Cancer Res. 1990 Mar 15; 50(6):1897-904. View in: PubMed

Ehlen T, Dubeau L. Loss of heterozygosity on chromosomal segments 3p, 6q and 11p in human ovarian carcinomas. Oncogene. 1990 Feb; 5(2):219-23. View in: PubMed

Shaw KJ, Do YS, Kjos S, Anderson PW, Shinagawa T, Dubeau L, Hsueh WA. Human decidua is a major source of renin. J Clin Invest. 1989 Jun; 83(6):2085-92. View in: PubMed

Ehlen T, Dubeau L. Detection of ras point mutations by polymerase chain reaction using mutation-specific, inosine-containing oligonucleotide primers. Biochem Biophys Res Commun. 1989 Apr 28; 160(2):441-7. View in: PubMed

Dubeau L, Jones PA, Rideout WM, Laug WE. Differential regulation of plasminogen activators by epidermal growth factor in normal and neoplastic human urothelium. Cancer Res. 1988 Oct 1; 48(19):5552-6. View in: PubMed

Dubeau L, Weinberg K, Jones PA, Nichols PW. Studies on immunoglobulin gene rearrangement in formalin-fixed, paraffin-embedded pathology specimens. Am J Pathol. 1988 Mar; 130(3):588-94. View in: PubMed

Ahlering TE, Dubeau L, Jones PA. A new in vivo model to study invasion and metastasis of human bladder carcinoma. Cancer Res. 1987 Dec 15; 47(24 Pt 1):6660-5. View in: PubMed

Dubeau L, Jones PA. Growth of normal and neoplastic urothelium and response to epidermal growth factor in a defined serum-free medium. Cancer Res. 1987 Apr 15; 47(8):2107-12. View in: PubMed

Dubeau L, Chandler LA, Gralow JR, Nichols PW, Jones PA. Southern blot analysis of DNA extracted from formalin-fixed pathology specimens. Cancer Res. 1986 Jun; 46(6):2964-9. View in: PubMed

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