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Lynda Diane Roman, MD
Associate Professor of Obstetrics & Gynecology
Division Chief, Gynecologic Oncology
Director, Gynecology Oncology Fellowship
Obstetrics & Gynecology
IRD 528 Off Campus Los Angeles
+1 323 409 3405


Dr. Roman completed her fellowship in gynecologic oncology at the MD Anderson Cancer Center in Houston, Texas in 1991. Presently, she serves as Director of the Division of Gynecologic Oncology at the University of Southern California, as well as the Director of Research and the Fellowship Program Director. Also, Dr. Roman is the co-director of the Lynne Cohen Preventive Cancer Care Clinic at the USC/Norris Cancer Center. she has recently been appointed to the governing council of the Society of Gynecologic Oncologists.


Single Marital Status and Infectious Mortality in Women With Cervical Cancer in the United States. Int J Gynecol Cancer. 2017 Jul 12. View in: PubMed

Risk of Subsequent Ovarian Cancer After Ovarian Conservation in Young Women With Stage I Endometrioid Endometrial Cancer. Obstet Gynecol. 2017 Jul 07. View in: PubMed

Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancer. Am J Obstet Gynecol. 2017 Jun 27. View in: PubMed

Significance of uterine corpus tumor invasion in early-stage cervical cancer. Eur J Surg Oncol. 2017 Feb 03. View in: PubMed

Role of hysterectomy and lymphadenectomy in the management of early-stage borderline ovarian tumors. Gynecol Oncol. 2017 Jan 26. View in: PubMed

Extent of pelvic lymphadenectomy and use of adjuvant vaginal brachytherapy for early-stage endometrial cancer. Gynecol Oncol. 2016 Dec 22. View in: PubMed

A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. Int J Cancer. 2016 Dec 15; 139(12):2646-2654. View in: PubMed

Tumor characteristics and survival outcomes of women with tamoxifen-related uterine carcinosarcoma. Gynecol Oncol. 2016 Dec 05. View in: PubMed

Ovarian Conservation and Overall Survival in Young Women With Early-Stage Cervical Cancer. Obstet Gynecol. 2016 Dec 02. View in: PubMed

Endoplasmic reticulum stress in complex atypical hyperplasia as a possible predictor of occult carcinoma and progestin response. Gynecol Oncol. 2016 Oct 19. View in: PubMed

Ovarian Conservation and Overall Survival in Young Women With Early-Stage Low-Grade Endometrial Cancer. Obstet Gynecol. 2016 Sep 5. View in: PubMed

Significance of venous thromboembolism in women with cervical cancer. Gynecol Oncol. 2016 Jun 24. View in: PubMed

Association of Low-Dose Aspirin and Survival of Women With Endometrial Cancer. Obstet Gynecol. 2016 Jun 6. View in: PubMed

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk. Obstet Gynecol. 2016 May; 127(5):828-36. View in: PubMed

Significance of histologic pattern of carcinoma and sarcoma components on survival outcomes of uterine carcinosarcoma. Ann Oncol. 2016 Apr 6. View in: PubMed

Contributing factors for menopausal symptoms after surgical staging for endometrial cancer. Menopause. 2015 Dec 29. View in: PubMed

Predictive Factor of Conversion to Laparotomy in Minimally Invasive Surgical Staging for Endometrial Cancer. Int J Gynecol Cancer. 2015 Nov 14. View in: PubMed

Tumor Characteristics and Survival Outcome of Endometrial Cancer Arising in Adenomyosis: An Exploratory Analysis. Ann Surg Oncol. 2015 Nov 5. View in: PubMed

Timing of intra-uterine manipulator insertion during minimally invasive surgical staging and results of pelvic cytology in endometrial cancer. J Minim Invasive Gynecol. 2015 Oct 13. View in: PubMed

Impact of depth and extent of lymphovascular space invasion on lymph node metastasis and recurrence patterns in endometrial cancer. J Surg Oncol. 2015 Sep 22. View in: PubMed

Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized poly-I:C. Clin Immunol. 2015 Sep 7. View in: PubMed

Characteristics of ovarian tumors of low malignant potential in BRCA mutation carriers: A case series. Gynecol Oncol Rep. 2015 Aug; 13:36-9. View in: PubMed

Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma. Eur J Cancer. 2015 Jul 31. View in: PubMed

Prediction of concurrent endometrial carcinoma in women with endometrial hyperplasia. Gynecol Oncol. 2015 Jul 31. View in: PubMed

Effects of imiquimod on vulvar Paget's disease: a systematic review of literature. Gynecol Oncol. 2015 Jul 17. View in: PubMed

Surgical menopause and increased risk of nonalcoholic fatty liver disease in endometrial cancer. Menopause. 2015 Jul 13. View in: PubMed

RECORD-2: phase II randomized study of everolimus and bevacizumab versus interferon a-2a and bevacizumab as first-line therapy in patients with metastatic renal cell carcinoma. Ann Oncol. 2015 Jul; 26(7):1378-84. View in: PubMed

In Reply. Obstet Gynecol. 2015 Jun; 125(6):1498. View in: PubMed

Significance of monocyte counts on tumor characteristics and survival outcome of women with endometrial cancer. Gynecol Oncol. 2015 May 23. View in: PubMed

Population distribution of lifetime risk of ovarian cancer in the United States. Cancer Epidemiol Biomarkers Prev. 2015 Apr; 24(4):671-6. View in: PubMed

Escalation of oncologic services at the end of life among patients with gynecologic cancer at an urban, public hospital. J Oncol Pract. 2015 Mar; 11(2):e163-9. View in: PubMed

Survival outcome of stage I ovarian clear cell carcinoma with lympho-vascular space invasion. Gynecol Oncol. 2015 Feb; 136(2):198-204. View in: PubMed

Time interval between endometrial biopsy and surgical staging for type I endometrial cancer: association between tumor characteristics and survival outcome. Obstet Gynecol. 2015 Feb; 125(2):424-33. View in: PubMed

Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium. PLoS One. 2015; 10(7):e0130909. View in: PubMed


Significance of adenomyosis on tumor progression and survival outcome of endometrial cancer. Ann Surg Oncol. 2014 Dec; 21(13):4246-55. View in: PubMed

Phase I clinical trial of temsirolimus and vinorelbine in advanced solid tumors. Cancer Chemother Pharmacol. 2014 Dec; 74(6):1227-34. View in: PubMed

Estrogen receptor expression and increased risk of lymphovascular space invasion in high-grade serous ovarian carcinoma. Gynecol Oncol. 2014 Jun; 133(3):473-9. View in: PubMed

Effect of lymphovascular space invasion on survival of stage I epithelial ovarian cancer. Obstet Gynecol. 2014 May; 123(5):957-65. View in: PubMed

Cervical conization of adenocarcinoma in situ: a predicting model of residual disease. Am J Obstet Gynecol. 2014 Apr; 210(4):366. e1-5. View in: PubMed

Phase III trial of nonpegylated liposomal doxorubicin in combination with trastuzumab and paclitaxel in HER2-positive metastatic breast cancer. Ann Oncol. 2014 Mar; 25(3):592-8. View in: PubMed

A phase II trial of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube. Gynecol Oncol. 2014 Mar; 132(3):517-25. View in: PubMed

Abdominal Aortic Resection and Y-Graft Placement to Achieve Complete Cytoreduction in Stage IIIc Ovarian Carcinoma. Obstet Gynecol. 2014 Feb; 123(2 Pt 2):486-8. View in: PubMed

[Results of surgical treatment of oral cavity cancer T1-2N0M0]. Vestn Khir Im I I Grek. 2014; 173(2):52-6. View in: PubMed

Final results from a randomized phase 3 study of FOLFIRI {+/-} panitumumab for second-line treatment of metastatic colorectal cancer. Ann Oncol. 2014 Jan; 25(1):107-16. View in: PubMed

[Immediate and long-term results of treatment after pelvic exenteration for locally advanced cervical cancer]. Vopr Onkol. 2014; 60(3):319-22. View in: PubMed

Endometrial echo complex thickness in postmenopausal endometrial cancer. Gynecol Oncol. 2013 Oct; 131(1):109-12. View in: PubMed

Reporting of quality measures in gynecologic oncology programs at Prospective Payment System (PPS)-Exempt Cancer Hospitals: an early glimpse into a challenging initiative. Gynecol Oncol. 2013 Sep; 130(3):403-6. View in: PubMed

Global, multicenter, randomized, phase II trial of gemcitabine and gemcitabine plus AGS-1C4D4 in patients with previously untreated, metastatic pancreatic cancer. Ann Oncol. 2013 Jul; 24(7):1792-801. View in: PubMed

Predictive model of venous thromboembolism in endometrial cancer. Gynecol Oncol. 2013 Mar; 128(3):544-51. View in: PubMed

Successful extraction of cardiac-extending intravenous leiomyomatosis through gonadal vein. Fertil Steril. 2012 Nov; 98(5):1341-1345. e1. View in: PubMed

Significance of lymphovascular space invasion in epithelial ovarian cancer. Cancer Med. 2012 Oct; 1(2):156-64. View in: PubMed

Phase II Study of Gemcitabine and Docetaxel in Recurrent Platinum Resistant Ovarian Cancer. Cancer Invest. 2012 May; 30(4):295-9. View in: PubMed

Significance of perioperative infection in survival of patients with ovarian cancer. Int J Gynecol Cancer. 2012 Feb; 22(2):245-53. View in: PubMed

[Pelvic exenteration in surgery for colorectal cancer]. Vopr Onkol. 2012; 58(3):363-8. View in: PubMed

Long-term pegylated liposomal doxorubicin use and oromaxillary squamous cell carcinoma in endometrial cancer. Oncologist. 2012; 17(12):1598-9. View in: PubMed

[Characteristics of tumor growth in patients with locally-advanced gastric cancer]. Vopr Onkol. 2011; 57(3):370-2. View in: PubMed

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. PLoS One. 2011; 6(12):e28141. View in: PubMed

Analysis of outcomes of microinvasive adenocarcinoma of the uterine cervix by treatment type. Obstet Gynecol. 2010 Nov; 116(5):1150-7. View in: PubMed

Overcoming platinum resistance in ovarian carcinoma. Expert Opin Investig Drugs. 2010 Nov; 19(11):1339-54. View in: PubMed

Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study. Ann Oncol. 2010 Aug; 21(8):1712-7. View in: PubMed

[Outcomes of surgical treatment for locally advanced gastric cancer]. Vopr Onkol. 2010; 56(1):24-8. View in: PubMed

Phase II trial of bevacizumab in the treatment of persistent or recurrent squamous cell carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol. 2009 Mar 1; 27(7):1069-74. View in: PubMed

[Palliative resection in esophageal cancer]. Vopr Onkol. 2009; 55(1):56-9. View in: PubMed

Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab. Clin Cancer Res. 2008 Nov 15; 14(22):7554-63. View in: PubMed

Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia. J Clin Oncol. 2008 Jan 1; 26(1):76-82. View in: PubMed

A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia. Gynecol Oncol. 2007 Sep; 106(3):558-66. View in: PubMed

Phase II clinical trial of docetaxel in refractory squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study. Am J Clin Oncol. 2007 Aug; 30(4):428-31. View in: PubMed

Therapeutic vaccination for HPV induced cervical cancers. Dis Markers. 2007; 23(4):337-52. View in: PubMed

Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status. J Clin Oncol. 2006 Sep 10; 24(26):4324-32. View in: PubMed

Feasibility of laparoscopic extraperitoneal surgical staging for locally advanced cervical carcinoma in a gynecologic oncology fellowship training program. J Minim Invasive Gynecol. 2006 Sep-Oct; 13(5):391-7. View in: PubMed

Endometrial cancer patients have a significant risk of harboring isolated tumor cells in histologically negative lymph nodes. Int J Gynecol Cancer. 2006 May-Jun; 16(3):1336-41. View in: PubMed

Influence of quantity of lymph vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix. Gynecol Oncol. 2006 Feb; 100(2):288-93. View in: PubMed

Pregnancy after radical vaginal trachelectomy: maybe not such a risky undertaking after all. Gynecol Oncol. 2005 Jul; 98(1):1-2. View in: PubMed

Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors. Gynecol Oncol. 2005 Apr; 97(1):266-70. View in: PubMed

Phase I clinical trial of topotecan and pegylated liposomal doxorubicin. Cancer Invest. 2005; 23(8):665-70. View in: PubMed

The impact of anti HPV vaccination on cervical cancer incidence and HPV induced cervical lesions: consequences for clinical management. Eur J Gynaecol Oncol. 2005; 26(2):129-42. View in: PubMed

Algorithm guides ICP infection investigation. Hosp Case Manag. 2004 Nov; 12(11):167-8. View in: PubMed

Extraperitoneal laparoscopic lymph node staging: the University of Southern California experience. Gynecol Oncol. 2004 Oct; 95(1):189-92. View in: PubMed

Phase II study of gemcitabine and weekly paclitaxel in recurrent platinum-resistant ovarian cancer. Gynecol Oncol. 2004 May; 93(2):493-8. View in: PubMed

Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy. Clin Cancer Res. 2004 Apr 15; 10(8):2681-6. View in: PubMed

[Comparative clinical evaluation of the effectiveness of modified radical mastectomy and organ-preserving therapy in localized breast cancer (pT1-2N0M0)]. Vopr Onkol. 2004; 50(1):99-100. View in: PubMed

Radical vaginal trachelectomy and pelvic lymphadenectomy for preservation of fertility in early cervical carcinoma. Gynecol Oncol. 2003 Mar; 88(3):419-23. View in: PubMed

Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: analysis of toxicities and predictors of outcome. Cancer. 2001 Jan 1; 91(1):90-100. View in: PubMed

The use of a pelvic displacement prosthesis to exclude the small intestine from the radiation field following radical hysterectomy. Gynecol Oncol. 2000 Dec; 79(3):438-43. View in: PubMed

A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. Clin Cancer Res. 2000 Sep; 6(9):3406-16. View in: PubMed

Phase II study of liposomal doxorubicin in advanced gynecologic cancers. Gynecol Oncol. 2000 Aug; 78(2):143-7. View in: PubMed

Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Asia Hepatitis Lamivudine Study Group. Gastroenterology. 2000 Jul; 119(1):172-80. View in: PubMed

A phase II study of gemcitabine and cisplatin in patients with advanced, persistent, or recurrent squamous cell carcinoma of the cervix. Gynecol Oncol. 2000 Jan; 76(1):63-6. View in: PubMed

[Ulcerated forms of gastric cancer as a clinical problem]. Vestn Khir Im I I Grek. 2000; 159(5):110-3. View in: PubMed

[Long-term outcome of surgical treatment of patients with esophageal cancer]. Vestn Khir Im I I Grek. 2000; 159(4):33-6. View in: PubMed

Cold-knife conization versus conization by the loop electrosurgical excision procedure: a randomized, prospective study. Am J Obstet Gynecol. 1999 Feb; 180(2 Pt 1):276-82. View in: PubMed

[Lymph node dissection in esophageal cancer]. Vestn Khir Im I I Grek. 1999; 158(5):50-3. View in: PubMed

A phase II trial of CPT-11 in recurrent squamous carcinoma of the cervix: a gynecologic oncology group study. Gynecol Oncol. 1998 Sep; 70(3):334-8. View in: PubMed

Carcinoembryonic antigen in women with isolated pelvic masses. Clinical utility? J Reprod Med. 1998 May; 43(5):403-7. View in: PubMed

Small cystic pelvic masses in older women: is surgical removal necessary? Gynecol Oncol. Small cystic pelvic masses in older women: is surgical removal necessary? Gynecol Oncol. 1998 Apr; 69(1):1-2. View in: PubMed

Influence of quantity of lymph-vascular space invasion on the risk of nodal metastases in women with early-stage squamous cancer of the cervix. Gynecol Oncol. 1998 Mar; 68(3):220-5. View in: PubMed

Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination. J Natl Cancer Inst. 1998 Feb 4; 90(3):238-42. View in: PubMed

Risk of residual invasive disease in women with microinvasive squamous cancer in a conization specimen. Obstet Gynecol. 1997 Nov; 90(5):759-64. View in: PubMed

Phase I/II study of intraperitoneal floxuridine and platinums (cisplatin and/or carboplatin). Gynecol Oncol. 1997 Aug; 66(2):290-4. View in: PubMed

Carboplatin as a radiation sensitizer in locally advanced cervical cancer: a pilot study. Gynecol Oncol. 1997 May; 65(2):336-42. View in: PubMed

Pelvic examination, tumor marker level, and gray-scale and Doppler sonography in the prediction of pelvic cancer. Obstet Gynecol. 1997 Apr; 89(4):493-500. View in: PubMed

Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation. J Clin Oncol. 1997 Mar; 15(3):987-93. View in: PubMed

[Successful surgical treatment of cancer with multiple location]. Vopr Onkol. 1997; 43(2):230. View in: PubMed

Residual disease in the uterus after preoperative radiotherapy and hysterectomy in stage IB cervical carcinoma. Am J Clin Oncol. 1996 Oct; 19(5):433-8. View in: PubMed

[Variants in the definitive organization of the lumbar lymph-conducting pathways in the applied aspect]. Vestn Khir Im I I Grek. 1996; 155(6):49-53. View in: PubMed

Preliminary analysis of the behavior of stage I ovarian serous tumors of low malignant potential: a Gynecologic Oncology Group study. J Clin Oncol. 1995 Nov; 13(11):2752-6. View in: PubMed

The role of endocervical curettage at cervical conization for high-grade dysplasia. Obstet Gynecol. 1995 Feb; 85(2):197-201. View in: PubMed

Differentiation of benign and malignant adnexal masses: relative value of gray-scale, color Doppler, and spectral Doppler sonography. AJR Am J Roentgenol. 1995 Feb; 164(2):381-6. View in: PubMed

Intraperitoneal 5-fluoro-2'-deoxyuridine (FUDR) and (S)-leucovorin for disease predominantly confined to the peritoneal cavity: a pharmacokinetic and toxicity study. Cancer Chemother Pharmacol. 1995; 37(1-2):32-8. View in: PubMed

The significance of positive margins in loop electrosurgical cone biopsies. Obstet Gynecol. 1994 Dec; 84(6):996-1000. View in: PubMed

Paclitaxel (Taxol) in heavily pretreated ovarian cancer: antitumor activity and complications. Ann Oncol. 1994 Nov; 5(9):827-33. View in: PubMed

Death from anaphylaxis to cisplatin: a case report. Gynecol Oncol. 1994 Apr; 53(1):121-2. View in: PubMed

Cervical cancer in pregnancy: reporting on planned delay in therapy. Obstet Gynecol. 1993 Oct; 82(4 Pt 1):598-602. View in: PubMed

Prognostic factors for patients undergoing simple hysterectomy in the presence of invasive cancer of the cervix. Gynecol Oncol. 1993 Aug; 50(2):179-84. View in: PubMed

Dedifferentiated extrauterine adenosarcoma responsive to chemotherapy. Gynecol Oncol. 1993 Jun; 49(3):389-94. View in: PubMed

Reasons for inappropriate simple hysterectomy in the presence of invasive cancer of the cervix. Obstet Gynecol. 1992 Apr; 79(4):485-9. View in: PubMed

High-dose, short-duration cisplatin/doxorubicin combination chemotherapy for advanced ovarian epithelial cancer. Cancer. 1991 Nov 1; 68(9):1890-4. View in: PubMed

Unsuspected invasive squamous cell carcinoma of the vulva in young women. Gynecol Oncol. 1991 May; 41(2):182-5. View in: PubMed

Primary adenocarcinoma of the breast arising in the vulva. Obstet Gynecol. 1990 Sep; 76(3 Pt 2):537-9. View in: PubMed

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