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Lynda Diane Roman, MD
Associate Professor of Obstetrics & Gynecology
Division Chief, Gynecologic Oncology
Director, Gynecology Oncology Fellowship
Obstetrics & Gynecology
IRD 528 Off Campus Los Angeles
+1 323 226 3405


Dr. Roman completed her fellowship in gynecologic oncology at the MD Anderson Cancer Center in Houston, Texas in 1991. Presently, she serves as Director of the Division of Gynecologic Oncology at the University of Southern California, as well as the Director of Research and the Fellowship Program Director. Also, Dr. Roman is the co-director of the Lynne Cohen Preventive Cancer Care Clinic at the USC/Norris Cancer Center. she has recently been appointed to the governing council of the Society of Gynecologic Oncologists.


Matsuo K, Machida H, Shoupe D, Melamed A, Muderspach LI, Roman LD, Wright JD. Ovarian Conservation and Overall Survival in Young Women With Early-Stage Low-Grade Endometrial Cancer. Obstet Gynecol. 2016 Sep 5. View in: PubMed

Matsuo K, Moeini A, Machida H, Fullerton ME, Shabalova A, Brunette LL, Roman LD. Significance of venous thromboembolism in women with cervical cancer. Gynecol Oncol. 2016 Jun 24. View in: PubMed

Matsuo K, Cahoon SS, Yoshihara K, Shida M, Kakuda M, Adachi S, Moeini A, Machida H, Garcia-Sayre J, Ueda Y, Enomoto T, Mikami M, Roman LD, Sood AK. Association of Low-Dose Aspirin and Survival of Women With Endometrial Cancer. Obstet Gynecol. 2016 Jun 6. View in: PubMed

Lee AW, Ness RB, Roman LD, Terry KL, Schildkraut JM, Chang-Claude J, Doherty JA, Menon U, Cramer DW, Gayther SA, Risch H, Gentry-Maharaj A, Goodman MT, Modugno F, Eilber U, Moysich KB, Berchuck A, Rossing MA, Jensen A, Wicklund KG, Cushing-Haugen KL, Hogdall E, Rudolph A, Thompson PJ, Wilkens LR, Kjaer SK, Carney ME, Stram DO, Ramus SJ, Wu AH, Pike MC, Pearce CL. Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk. Obstet Gynecol. 2016 May; 127(5):828-36. View in: PubMed

Matsuo K, Gualtieri MR, Cahoon SS, Toboni MD, Machida H, Moeini A, Hasegawa K, Shoupe D, Roman LD. Contributing factors for menopausal symptoms after surgical staging for endometrial cancer. Menopause. 2015 Dec 29. View in: PubMed

Matsuo K, Jung CE, Hom MS, Gualtieri MR, Randazzo SC, Kanao H, Yessaian AA, Roman LD. Predictive Factor of Conversion to Laparotomy in Minimally Invasive Surgical Staging for Endometrial Cancer. Int J Gynecol Cancer. 2015 Nov 14. View in: PubMed

Matsuo K, Moeini A, Machida H, Scannell CA, Casabar JK, Kakuda M, Adachi S, Garcia-Sayre J, Ueda Y, Roman LD. Tumor Characteristics and Survival Outcome of Endometrial Cancer Arising in Adenomyosis: An Exploratory Analysis. Ann Surg Oncol. 2015 Nov 5. View in: PubMed

Machida H, Casey JP, Garcia-Sayre J, Jung CE, Casabar JK, Moeini A, Kato K, Roman LD, Matsuo K. Timing of intra-uterine manipulator insertion during minimally invasive surgical staging and results of pelvic cytology in endometrial cancer. J Minim Invasive Gynecol. 2015 Oct 13. View in: PubMed

Matsuo K, Garcia-Sayre J, Medeiros F, Casabar JK, Machida H, Moeini A, Roman LD. Impact of depth and extent of lymphovascular space invasion on lymph node metastasis and recurrence patterns in endometrial cancer. J Surg Oncol. 2015 Sep 22. View in: PubMed

Da Silva DM, Woodham AW, Skeate JG, Rijkee LK, Taylor JR, Brand HE, Muderspach LI, Roman LD, Yessaian AA, Pham HQ, Matsuo K, Lin YG, McKee GM, Salazar AM, Martin Kast W. Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized poly-I:C. Clin Immunol. 2015 Sep 7. View in: PubMed

Matsuo K, Tierney KE, Schneider DM, Mhawech-Fauceglia P, Roman LD, Gershenson DM. Characteristics of ovarian tumors of low malignant potential in BRCA mutation carriers: A case series. Gynecol Oncol Rep. 2015 Aug; 13:36-9. View in: PubMed

Matsuo K, Ramzan AA, Gualtieri MR, Mhawech-Fauceglia P, Machida H, Moeini A, Dancz CE, Ueda Y, Roman LD. Prediction of concurrent endometrial carcinoma in women with endometrial hyperplasia. Gynecol Oncol. 2015 Jul 31. View in: PubMed

Matsuo K, Hasegawa K, Yoshino K, Murakami R, Hisamatsu T, Stone RL, Previs RA, Hansen JM, Ikeda Y, Miyara A, Hiramatsu K, Enomoto T, Fujiwara K, Matsumura N, Konishi I, Roman LD, Gabra H, Fotopoulou C, Sood AK. Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma. Eur J Cancer. 2015 Jul 31. View in: PubMed

Machida H, Moeini A, Roman LD, Matsuo K. Effects of imiquimod on vulvar Paget's disease: a systematic review of literature. Gynecol Oncol. 2015 Jul 17. View in: PubMed

Matsuo K, Gualtieri MR, Cahoon SS, Jung CE, Paulson RJ, Shoupe D, Muderspach LI, Wakatsuki A, Wright JD, Roman LD. Surgical menopause and increased risk of nonalcoholic fatty liver disease in endometrial cancer. Menopause. 2015 Jul 13. View in: PubMed

Matsuo K, Opper NR, Roman LD. In Reply. Obstet Gynecol. 2015 Jun; 125(6):1498. View in: PubMed

Matsuo K, Hom MS, Moeini A, Machida H, Takeshima N, Roman LD, Sood AK. Significance of monocyte counts on tumor characteristics and survival outcome of women with endometrial cancer. Gynecol Oncol. 2015 May 23. View in: PubMed

Pearce CL, Stram DO, Ness RB, Stram DA, Roman LD, Templeman C, Lee AW, Menon U, Fasching PA, McAlpine JN, Doherty JA, Modugno F, Schildkraut JM, Rossing MA, Huntsman DG, Wu AH, Berchuck A, Pike MC, Pharoah PD. Population distribution of lifetime risk of ovarian cancer in the United States. Cancer Epidemiol Biomarkers Prev. 2015 Apr; 24(4):671-6. View in: PubMed

Wu E, Rogers A, Ji L, Sposto R, Church T, Roman L, Tripathy D, Lin YG. Escalation of oncologic services at the end of life among patients with gynecologic cancer at an urban, public hospital. J Oncol Pract. 2015 Mar; 11(2):e163-9. View in: PubMed

Matsuo K, Yoshino K, Hasegawa K, Murakami R, Ikeda Y, Adachi S, Hiramatsu K, Yokoyama T, Nishimura M, Sheridan TB, Enomoto T, Fujiwara K, Matsumura N, Konishi I, Fotopoulou C, Roman LD, Sood AK. Survival outcome of stage I ovarian clear cell carcinoma with lympho-vascular space invasion. Gynecol Oncol. 2015 Feb; 136(2):198-204. View in: PubMed

Matsuo K, Opper NR, Ciccone MA, Garcia J, Tierney KE, Baba T, Muderspach LI, Roman LD. Time interval between endometrial biopsy and surgical staging for type I endometrial cancer: association between tumor characteristics and survival outcome. Obstet Gynecol. 2015 Feb; 125(2):424-33. View in: PubMed

Lawrenson K, Pakzamir E, Liu B, Lee JM, Delgado MK, Duncan K, Gayther SA, Liu S, Roman L, Mhawech-Fauceglia P. Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium. PLoS One. 2015; 10(7):e0130909. View in: PubMed

Piatek CI, Raja GL, Ji L, Gitlitz BJ, Dorff TB, Quinn DI, Hu J, El-Khoueiry AB, Pham HQ, Roman L, Garcia AA. Phase I clinical trial of temsirolimus and vinorelbine in advanced solid tumors. Cancer Chemother Pharmacol. 2014 Dec; 74(6):1227-34. View in: PubMed

Matsuo K, Cahoon SS, Gualtieri M, Scannell CA, Jung CE, Takano T, Paulson RJ, Muderspach LI, Roman LD. Significance of adenomyosis on tumor progression and survival outcome of endometrial cancer. Ann Surg Oncol. 2014 Dec; 21(13):4246-55. View in: PubMed

Matsuo K, Sheridan TB, Mabuchi S, Yoshino K, Hasegawa K, Studeman KD, Im DD, Rosenshein NB, Roman LD, Sood AK. Estrogen receptor expression and increased risk of lymphovascular space invasion in high-grade serous ovarian carcinoma. Gynecol Oncol. 2014 Jun; 133(3):473-9. View in: PubMed

Matsuo K, Yoshino K, Hiramatsu K, Banzai C, Hasegawa K, Yasuda M, Nishimura M, Sheridan TB, Ikeda Y, Shiki Y, Mabuchi S, Enomoto T, Kimura T, Fujiwara K, Roman LD, Sood AK. Effect of lymphovascular space invasion on survival of stage I epithelial ovarian cancer. Obstet Gynecol. 2014 May; 123(5):957-65. View in: PubMed

Tierney KE, Lin PS, Amezcua C, Matsuo K, Ye W, Felix JC, Roman LD. Cervical conization of adenocarcinoma in situ: a predicting model of residual disease. Am J Obstet Gynecol. 2014 Apr; 210(4):366. e1-5. View in: PubMed

Herzog TJ, Monk BJ, Rose PG, Braly P, Hines JF, Bell MC, Wenham RM, Secord AA, Roman LD, Einstein MH, Drake RD, Childs BH. A phase II trial of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube. Gynecol Oncol. 2014 Mar; 132(3):517-25. View in: PubMed

Lentz SE, Tierney KE, Weaver FA, Roman LD. Abdominal Aortic Resection and Y-Graft Placement to Achieve Complete Cytoreduction in Stage IIIc Ovarian Carcinoma. Obstet Gynecol. 2014 Feb; 123(2 Pt 2):486-8. View in: PubMed

Chandavarkar U, Kuperman JM, Muderspach LI, Opper N, Felix JC, Roman L. Endometrial echo complex thickness in postmenopausal endometrial cancer. Gynecol Oncol. 2013 Oct; 131(1):109-12. View in: PubMed

Cohn DE, Leitao M, Levenback C, Berkowitz R, Roman L, Lucci J, Kim S, Lancaster J, Odunsi K, Wakabayashi M, Goff BA. Reporting of quality measures in gynecologic oncology programs at Prospective Payment System (PPS)-Exempt Cancer Hospitals: an early glimpse into a challenging initiative. Gynecol Oncol. 2013 Sep; 130(3):403-6. View in: PubMed

Matsuo K, Yessaian AA, Lin YG, Pham HQ, Muderspach LI, Liebman HA, Morrow CP, Roman LD. Predictive model of venous thromboembolism in endometrial cancer. Gynecol Oncol. 2013 Mar; 128(3):544-51. View in: PubMed

Matsuo K, Fleischman F, Ghattas CS, Gabrielyan AS, Ballard CA, Roman LD, Morrow CP. Successful extraction of cardiac-extending intravenous leiomyomatosis through gonadal vein. Fertil Steril. 2012 Nov; 98(5):1341-1345. e1. View in: PubMed

Matsuo K, Sheridan TB, Yoshino K, Miyake T, Hew KE, Im DD, Rosenshein NB, Mabuchi S, Enomoto T, Kimura T, Sood AK, Roman LD. Significance of lymphovascular space invasion in epithelial ovarian cancer. Cancer Med. 2012 Oct; 1(2):156-64. View in: PubMed

Garcia AA, Yessaian A, Pham H, Facio G, Muderspach L, Roman L. Phase II Study of Gemcitabine and Docetaxel in Recurrent Platinum Resistant Ovarian Cancer. Cancer Invest. 2012 May; 30(4):295-9. View in: PubMed

Matsuo K, Prather CP, Ahn EH, Eno ML, Tierney KE, Yessaian AA, Im DD, Rosenshein NB, Roman LD. Significance of perioperative infection in survival of patients with ovarian cancer. Int J Gynecol Cancer. 2012 Feb; 22(2):245-53. View in: PubMed

Matsuo K, Blake EA, Yessaian AA, Roman LD. Long-term pegylated liposomal doxorubicin use and oromaxillary squamous cell carcinoma in endometrial cancer. Oncologist. 2012; 17(12):1598-9. View in: PubMed

Campan M, Moffitt M, Houshdaran S, Shen H, Widschwendter M, Daxenbichler G, Long T, Marth C, Laird-Offringa IA, Press MF, Dubeau L, Siegmund KD, Wu AH, Groshen S, Chandavarkar U, Roman LD, Berchuck A, Pearce CL, Laird PW. Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. PLoS One. 2011; 6(12):e28141. View in: PubMed

Matsuo K, Lin YG, Roman LD, Sood AK. Overcoming platinum resistance in ovarian carcinoma. Expert Opin Investig Drugs. 2010 Nov; 19(11):1339-54. View in: PubMed

Reynolds EA, Tierney K, Keeney GL, Felix JC, Weaver AL, Roman LD, Cliby WA. Analysis of outcomes of microinvasive adenocarcinoma of the uterine cervix by treatment type. Obstet Gynecol. 2010 Nov; 116(5):1150-7. View in: PubMed

Monk BJ, Sill MW, Burger RA, Gray HJ, Buekers TE, Roman LD. Phase II trial of bevacizumab in the treatment of persistent or recurrent squamous cell carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol. 2009 Mar 1; 27(7):1069-74. View in: PubMed

Schultheis AM, Lurje G, Rhodes KE, Zhang W, Yang D, Garcia AA, Morgan R, Gandara D, Scudder S, Oza A, Hirte H, Fleming G, Roman L, Lenz HJ. Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab. Clin Cancer Res. 2008 Nov 15; 14(22):7554-63. View in: PubMed

Garcia AA, Hirte H, Fleming G, Yang D, Tsao-Wei DD, Roman L, Groshen S, Swenson S, Markland F, Gandara D, Scudder S, Morgan R, Chen H, Lenz HJ, Oza AM. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia. J Clin Oncol. 2008 Jan 1; 26(1):76-82. View in: PubMed

Garcia AA, Blessing JA, Vaccarello L, Roman LD. Phase II clinical trial of docetaxel in refractory squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study. Am J Clin Oncol. 2007 Aug; 30(4):428-31. View in: PubMed

Brinkman JA, Hughes SH, Stone P, Caffrey AS, Muderspach LI, Roman LD, Weber JS, Kast WM. Therapeutic vaccination for HPV induced cervical cancers. Dis Markers. 2007; 23(4):337-52. View in: PubMed

Gordon MS, Matei D, Aghajanian C, Matulonis UA, Brewer M, Fleming GF, Hainsworth JD, Garcia AA, Pegram MD, Schilder RJ, Cohn DE, Roman L, Derynck MK, Ng K, Lyons B, Allison DE, Eberhard DA, Pham TQ, Dere RC, Karlan BY. Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status. J Clin Oncol. 2006 Sep 10; 24(26):4324-32. View in: PubMed

Lowe MP, Bahador A, Muderspach LI, Burnett A, Santos L, Caffrey A, Roman LD, Morrow CP. Feasibility of laparoscopic extraperitoneal surgical staging for locally advanced cervical carcinoma in a gynecologic oncology fellowship training program. J Minim Invasive Gynecol. 2006 Sep-Oct; 13(5):391-7. View in: PubMed

Chernofsky MR, Felix JC, Muderspach LI, Morrow CP, Ye W, Groshen SG, Roman LD. Influence of quantity of lymph vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix. Gynecol Oncol. 2006 Feb; 100(2):288-93. View in: PubMed

Roman LD. Pregnancy after radical vaginal trachelectomy: maybe not such a risky undertaking after all. Gynecol Oncol. 2005 Jul; 98(1):1-2. View in: PubMed

Mateo R, Singh G, Jabbour N, Palmer S, Genyk Y, Roman L. Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors. Gynecol Oncol. 2005 Apr; 97(1):266-70. View in: PubMed

Garcia AA, Roman L, Muderspach L, O'meara A, Facio G, Edwards S, Burnett A. Phase I clinical trial of topotecan and pegylated liposomal doxorubicin. Cancer Invest. 2005; 23(8):665-70. View in: PubMed

Burnett AF, O'Meara AT, Bahador A, Roman LD, Morrow CP. Extraperitoneal laparoscopic lymph node staging: the University of Southern California experience. Gynecol Oncol. 2004 Oct; 95(1):189-92. View in: PubMed

Garcia AA, O'Meara A, Bahador A, Facio G, Jeffers S, Kim DY, Roman L. Phase II study of gemcitabine and weekly paclitaxel in recurrent platinum-resistant ovarian cancer. Gynecol Oncol. 2004 May; 93(2):493-8. View in: PubMed

Nouriani M, Bahador A, Berek JS, Cheng JP, Chi DS, Cliby WA, Del Priore G, Dodson MK, Duggan BD, Gershenson DM, Lentz SE, Penson RT, Robinson WR, Rodriguez M, Roman LD, Yu MC, Zempolich K, Dubeau L. Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy. Clin Cancer Res. 2004 Apr 15; 10(8):2681-6. View in: PubMed

Burnett AF, Roman LD, O'Meara AT, Morrow CP. Radical vaginal trachelectomy and pelvic lymphadenectomy for preservation of fertility in early cervical carcinoma. Gynecol Oncol. 2003 Mar; 88(3):419-23. View in: PubMed

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