Faculty

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Shinwu Jeong, PhD
Associate Professor of Research Ophthalmology
Ophthalmology
CSA 2250 Alcazar St. CSA 215 Health Sciences Campus Los Angeles
+1 323 442 2099

Publications

Clinical outcomes of low-dose and high-dose postoperative radioiodine therapy in patients with intermediate-risk differentiated thyroid cancer. Nucl Med Commun. 2017 Mar; 38(3):228-233. View in: PubMed

Engineering of radioiodine-labeled gold core-shell nanoparticles as efficient nuclear medicine imaging agents for trafficking of dendritic cells. ACS Appl Mater Interfaces. 2017 Feb 20. View in: PubMed

Multimodality Imaging of Bone Marrow-Derived Dendritic Cell Migration and Antitumor Immunity. Transl Oncol. 2017 Feb 16; 10(2):262-270. View in: PubMed

Visualization of Macrophage Recruitment to Inflammation Lesions using Highly Sensitive and Stable Radionuclide-Embedded Gold Nanoparticles as a Nuclear Bio-Imaging Platform. Theranostics. 2017; 7(4):926-934. View in: PubMed

Prognostic Value of Metabolic Parameters of 18F-FDG PET/CT and Apparent Diffusion Coefficient of MRI in Hepatocellular Carcinoma. Clin Nucl Med. 2016 Dec 09. View in: PubMed

Role of pulmonary macrophages in initiation of lung metastasis in anaplastic thyroid cancer. Int J Cancer. 2016 Dec 1; 139(11):2583-92. View in: PubMed

Non-invasive visualization of mast cell recruitment and its effects in lung cancer by optical reporter gene imaging and glucose metabolism monitoring. Biomaterials. 2016 Oct 13; 112:192-203. View in: PubMed

Clinical impact of (18) F-FDG positron emission tomography/CT on adenoid cystic carcinoma of the head and neck. Head Neck. 2016 Oct 11. View in: PubMed

Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine. Prog Retin Eye Res. 2016 Sep 22. View in: PubMed

Combined Positron Emission Tomography and Cerenkov Luminescence Imaging of Sentinel Lymph Nodes Using PEGylated Radionuclide-Embedded Gold Nanoparticles. Small. 2016 Sep; 12(35):4894-4901. View in: PubMed

Prognostic Value of Volumetric Parameters Measured by Pretreatment 18F FDG PET/CT in Patients With Cutaneous Malignant Melanoma. Clin Nucl Med. 2016 Jun; 41(6):e266-73. View in: PubMed

Granulomatous Prostatitis After Intravesical Bacillus Calmette-Guérin Instillation Therapy: A Potential Cause of Incidental F-18 FDG Uptake in the Prostate Gland on F-18 FDG PET/CT in Patients with Bladder Cancer. Nucl Med Mol Imaging. 2016 Mar; 50(1):31-7. View in: PubMed

Visualization of the Biological Behavior of Tumor-Associated Macrophages in Living Mice with Colon Cancer Using Multimodal Optical Reporter Gene Imaging. Neoplasia. 2016 Mar; 18(3):133-41. View in: PubMed

Quantification of Intratumoral Metabolic Macroheterogeneity on 18F-FDG PET/CT and Its Prognostic Significance in Pathologic N0 Squamous Cell Lung Carcinoma. Clin Nucl Med. 2016 Feb; 41(2):e70-5. View in: PubMed

A cell-based screening assay to identify pharmaceutical compounds that enhance the regenerative quality of corneal repair. Wound Repair Regen. 2016 Jan; 24(1):89-99. View in: PubMed

In Vivo therapeutic potential of mesenchymal stem cell-derived extracellular vesicles with optical imaging reporter in tumor mice model. Sci Rep. 2016; 6:30418. View in: PubMed

Analysis of Clinical Factors for the Determination of Optimal Serum Level of Thyrotropin After Recombinant Human Thyroid-Stimulating Hormone Administration. Nucl Med Mol Imaging. 2015 Dec; 49(4):268-75. View in: PubMed

Inverse Agonist of Estrogen-Related Receptor ? Enhances Sodium Iodide Symporter Function Through Mitogen-Activated Protein Kinase Signaling in Anaplastic Thyroid Cancer Cells. J Nucl Med. 2015 Nov; 56(11):1690-6. View in: PubMed

Combined Fluorescence and Magnetic Resonance Imaging of Primary Macrophage Migration to Sites of Acute Inflammation Using Near-Infrared Fluorescent Magnetic Nanoparticles. Mol Imaging Biol. 2015 Oct; 17(5):643-51. View in: PubMed

Whole-Body Metabolic Tumor Volume, as Determined by (18)F-FDG PET/CT, as a Prognostic Factor of Outcome for Patients With Breast Cancer Who Have Distant Metastasis. AJR Am J Roentgenol. 2015 Oct; 205(4):878-85. View in: PubMed

Radioiodine Scan Index: A Simplified, Quantitative Treatment Response Parameter for Metastatic Thyroid Carcinoma. Nucl Med Mol Imaging. 2015 Sep; 49(3):174-81. View in: PubMed

Prognostic Significance of Intratumoral Metabolic Heterogeneity on 18F-FDG PET/CT in Pathological N0 Non-Small Cell Lung Cancer. Clin Nucl Med. 2015 Sep; 40(9):708-14. View in: PubMed

Solitary Splenic Metastasis From Hepatocellular Carcinoma Detected on 18F-FDG PET/CT. Clin Nucl Med. 2015 Jun; 40(6):e325-7. View in: PubMed

Role of SUVmax and GLUT-1 Expression in Determining Tumor Aggressiveness in Patients With Clinical Stage I Endometrioid Endometrial Cancer. Int J Gynecol Cancer. 2015 Jun; 25(5):843-9. View in: PubMed

Identification of a Novel Mucin Gene HCG22 Associated with Steroid-Induced Ocular Hypertension. Invest Ophthalmol Vis Sci. 2015 Mar 26. View in: PubMed

Quantitative metabolic parameters measured on F-18 FDG PET/CT predict survival after relapse in patients with relapsed epithelial ovarian cancer. Gynecol Oncol. 2015 Mar; 136(3):498-504. View in: PubMed

Size measurement of the thyroid gland on a magnified pinhole thyroid scan using an ultrasonic device measuring distance from the pinhole to the thyroid gland. Ann Nucl Med. 2015 Feb; 29(2):111-7. View in: PubMed

Incompletely dissolved radioiodine capsule as a likely cause of false-positive whole-body scan in thyroid cancer. Clin Nucl Med. 2015 Feb; 40(2):177-8. View in: PubMed

Tracking of dendritic cell migration into lymph nodes using molecular imaging with sodium iodide symporter and enhanced firefly luciferase genes. Sci Rep. 2015; 5:9865. View in: PubMed

Loss of CD147 results in impaired epithelial cell differentiation and malformation of the meibomian gland. Cell Death Dis. 2015; 6:e1726. View in: PubMed

Biological Production of an Integrin avß3 Targeting Imaging Probe and Functional Verification. Biomed Res Int. 2015; 2015:681012. View in: PubMed

Preoperative Prediction of Cervical Lymph Node Metastasis Using Primary Tumor SUVmax on 18F-FDG PET/CT in Patients with Papillary Thyroid Carcinoma. PLoS One. 2015; 10(12):e0144152. View in: PubMed

Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye. PLoS One. 2015; 10(9):e0138958. View in: PubMed

Expression and Functional Role of Orphan Receptor GPR158 in Prostate Cancer Growth and Progression. PLoS One. 2015; 10(2):e0117758. View in: PubMed

Chondrogenesis in scleral stem/progenitor cells and its association with form-deprived myopia in mice. Mol Vis. 2015; 21:138-47. View in: PubMed

Potential Therapeutic Effect of Natural Killer Cells on Doxorubicin-Resistant Breast Cancer Cells In Vitro. PLoS One. 2015; 10(8):e0136209. View in: PubMed

Comparison of the Prognostic Value of F-18 Pet Metabolic Parameters of Primary Tumors and Regional Lymph Nodes in Patients with Locally Advanced Cervical Cancer Who Are Treated with Concurrent Chemoradiotherapy. PLoS One. 2015; 10(9):e0137743. View in: PubMed

Superiority of delayed risk stratification in differentiated thyroid cancer after total thyroidectomy and radioactive iodine ablation. Nucl Med Commun. 2014 Nov; 35(11):1119-26. View in: PubMed

Emptying effect of massage on parotid gland radioiodine content. Nucl Med Commun. 2014 Nov; 35(11):1127-31. View in: PubMed

Metabolic parameters using ¹8F-FDG PET/CT correlate with occult lymph node metastasis in squamous cell lung carcinoma. Eur J Nucl Med Mol Imaging. 2014 Nov; 41(11):2051-7. View in: PubMed

Incidental detection of increased (18)F-FDG uptake and its follow-up in patients with granulomatous prostatitis after BCG treatment for urinary bladder cancer. Hell J Nucl Med. 2014 Sep-Dec; 17(3):204-7. View in: PubMed

Clinical applications of SPECT/CT after first I-131 ablation in patients with differentiated thyroid cancer. Clin Endocrinol (Oxf). 2014 Sep; 81(3):445-51. View in: PubMed

Difference of clinical and radiological characteristics according to radioiodine avidity in pulmonary metastases of differentiated thyroid cancer. Nucl Med Mol Imaging. 2014 Mar; 48(1):55-62. View in: PubMed

Prediction for recurrence using F-18 FDG PET/CT in pathologic N0 lung adenocarcinoma after curative surgery. Ann Surg Oncol. 2014 Feb; 21(2):589-96. View in: PubMed

Prognostic implication of intratumoral metabolic heterogeneity in invasive ductal carcinoma of the breast. BMC Cancer. 2014; 14:585. View in: PubMed

Recurrence of a functional adrenocortical oncocytoma of borderline malignant potential showing high FDG uptake on 18F-FDG PET/CT. Ann Nucl Med. 2014 Jan; 28(1):69-73. View in: PubMed

Metabolic tumor volume by positron emission tomography/computed tomography as a clinical parameter to determine therapeutic modality for early stage Hodgkin's lymphoma. Cancer Sci. 2013 Dec; 104(12):1656-61. View in: PubMed

Prognostic value of whole-body metabolic tumour volume and total lesion glycolysis measured on ¹8F-FDG PET/CT in patients with extranodal NK/T-cell lymphoma. Eur J Nucl Med Mol Imaging. 2013 Sep; 40(9):1321-9. View in: PubMed

Biliary Flow in Septate Gallbladder on Hepatobiliary Scintigraphy with SPECT/CT. Nucl Med Mol Imaging. 2013 Sep; 47(3):220-1. View in: PubMed

Extra-thoracic tumor burden but not thoracic tumor burden on (18)F-FDG PET/CT is an independent prognostic biomarker for extensive-disease small cell lung cancer. Lung Cancer. 2013 Aug; 81(2):218-25. View in: PubMed

Salivary gland function 5 years after radioactive iodine ablation in patients with differentiated thyroid cancer: direct comparison of pre- and postablation scintigraphies and their relation to xerostomia symptoms. Thyroid. 2013 May; 23(5):609-16. View in: PubMed

Estimation of true serum thyroglobulin concentration using simultaneous measurement of serum antithyroglobulin antibody. Int J Endocrinol. 2013; 2013:210639. View in: PubMed

18F-FDG uptake by metastatic axillary lymph nodes on pretreatment PET/CT as a prognostic factor for recurrence in patients with invasive ductal breast cancer. J Nucl Med. 2012 Sep; 53(9):1337-44. View in: PubMed

Interaction of clusterin and matrix metalloproteinase-9 and its implication for epithelial homeostasis and inflammation. Am J Pathol. 2012 May; 180(5):2028-39. View in: PubMed

Prognostic implications of microscopic involvement of surgical resection margin in patients with differentiated papillary thyroid cancer after high-dose radioactive iodine ablation. Ann Nucl Med. 2012 May; 26(4):311-8. View in: PubMed

Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells. Epigenetics Chromatin. 2012; 5(1):3. View in: PubMed

Combined E7-dendritic cell-based immunotherapy and human sodium/iodide symporter radioiodine gene therapy with monitoring of antitumor effects by bioluminescent imaging in a mouse model of uterine cervical cancer. Cancer Biother Radiopharm. 2011 Dec; 26(6):671-9. View in: PubMed

Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors. Bioorg Med Chem Lett. 2011 Jul 15; 21(14):4203-5. View in: PubMed

Prognostic Value of Primary Tumor Uptake on F-18 FDG PET/CT in Patients with Invasive Ductal Breast Cancer. Nucl Med Mol Imaging. 2011 Jun; 45(2):117-24. View in: PubMed

Neurolymphomatosis on F-18 FDG PET/CT and MRI Findings: A Case Report. Nucl Med Mol Imaging. 2011 Mar; 45(1):76-8. View in: PubMed

Combined Cerenkov luminescence and nuclear imaging of radioiodine in the thyroid gland and thyroid cancer cells expressing sodium iodide symporter: initial feasibility study. Endocr J. 2011; 58(7):575-83. View in: PubMed

Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. PLoS Genet. 2011; 7(2):e1001286. View in: PubMed

A novel mechanism of increased infections in contact lens wearers. Invest Ophthalmol Vis Sci. 2011; 52(12):9188-94. View in: PubMed

JNK-mediated transcriptional upregulation of RhoB is critical for apoptosis of HCT-116 colon cancer cells by a novel diarylsulfonylurea derivative. Apoptosis. 2010 Dec; 15(12):1540-8. View in: PubMed

Impact of medication discontinuation on increased intestinal FDG accumulation in diabetic patients treated with metformin. AJR Am J Roentgenol. 2010 Dec; 195(6):1404-10. View in: PubMed

Incidental pituitary uptake on whole-body 18F-FDG PET/CT: a multicentre study. Eur J Nucl Med Mol Imaging. 2010 Dec; 37(12):2334-43. View in: PubMed

False-Positive Axillary Lymph Node on F-18 FDG PET/CT due to Moxibustion Therapy. Nucl Med Mol Imaging. 2010 Dec; 44(4):307-8. View in: PubMed

Trafficking macrophage migration using reporter gene imaging with human sodium iodide symporter in animal models of inflammation. J Nucl Med. 2010 Oct; 51(10):1637-43. View in: PubMed

Rituximab-induced pneumonitis on F-18 FDG PET/CT in patient with non-Hodgkin lymphoma. Clin Nucl Med. 2010 Aug; 35(8):601-3. View in: PubMed

Isolated facial muscle metastasis from renal cell carcinoma on F-18 FDG PET/CT. Clin Nucl Med. 2010 Apr; 35(4):263-4. View in: PubMed

Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol Cell Biol. 2009 Oct; 29(19):5366-76. View in: PubMed

Synthesis and biological evaluation of 3,5-diaminoindazoles as cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett. 2008 Apr 1; 18(7):2292-5. View in: PubMed

Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island. Cancer Cell. 2007 Nov; 12(5):432-44. View in: PubMed

Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer Res. 2007 Jul 1; 67(13):6400-8. View in: PubMed

3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation. Bioorg Med Chem Lett. 2007 Mar 1; 17(5):1284-7. View in: PubMed

Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting. PLoS Genet. 2006 Sep 22; 2(9):e160. View in: PubMed

Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14080-5. View in: PubMed

Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level. Nucleic Acids Res. 2005; 33(20):e176. View in: PubMed

Lasonolide A: structural revision and total synthesis. J Org Chem. 2003 Oct 17; 68(21):8080-7. View in: PubMed

Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma. Biochem Biophys Res Commun. 2003 Jul 18; 307(1):52-63. View in: PubMed

Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines. Cancer Res. 2003 Feb 1; 63(3):621-6. View in: PubMed

Synthesis of (+)-Lasonolide A: (-)-lasonolide A is the biologically active enantiomer. Bioorg Med Chem Lett. 2002 Dec 16; 12(24):3519-20. View in: PubMed

A novel class of highly potent, selective, and non-peptidic inhibitor of Ras farnesyltransferase (FTase). Bioorg Med Chem Lett. 2001 Dec 3; 11(23):3069-72. View in: PubMed

The yeast transcription terminator for RNA polymerase I is designed to prevent polymerase slippage. J Biol Chem. 1996 Jul 5; 271(27):16104-10. View in: PubMed

The release element of the yeast polymerase I transcription terminator can function independently of Reb1p. Mol Cell Biol. 1995 Nov; 15(11):5929-36. View in: PubMed

xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity. Mol Cell Biol. 1994 May; 14(5):2871-82. View in: PubMed

Micrococcal nuclease digestion of nuclei reveals extended nucleosome ladders having anomalous DNA lengths for chromatin assembled on non-replicating plasmids in transfected cells. Nucleic Acids Res. 1994 Feb 11; 22(3):370-5. View in: PubMed

DNA sequence affects nucleosome ordering on replicating plasmids in transfected COS-1 cells and in vitro. J Biol Chem. 1994 Jan 21; 269(3):2197-205. View in: PubMed

Chromatin assembly on plasmid DNA in vitro. Apparent spreading of nucleosome alignment from one region of pBR327 by histone H5. J Mol Biol. 1991 Dec 20; 222(4):1131-47. View in: PubMed

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