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Sonia K. Ramsy, MD
Professor of Clinical Pediatrics
CHL Mail Stop 78 Off Campus Los Angeles
+1 323 361 5924


Research interests, include: Probiotics and studying the gut micro biome. Ongoing research studies, include: 1. Studies to investigate the role of gut micro biome in a number of pediatric disorders. 2. Studying the effect of probiotics and how they modify the gut microbiota. 3. NIH-funding to study the effect of probiotics on children with irritable bowel syndrome and how probiotics modify gut micro biota.


Ng VL, Haber BH, Magee JC, Miethke A, Murray KF, Michail S, Karpen SJ, Kerkar N, Molleston JP, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Turmelle YP, Alonso EM, Sherker AH, Sokol RJ. Medical status of 219 children with biliary atresia surviving long-term with their native livers: results from a north american multicenter consortium. J Pediatr. 2014 Sep; 165(3):539-546. e2. View in: PubMed

Kosmadakis G, Smirloglou D, Gobou A, Draganis T, Michail S. Hemodialysis treatment on an adult patient with Down syndrome associated with ectopic right kidney chronic obstructive nephropathy and secondary amyloidosis. Saudi J Kidney Dis Transpl. 2013 Mar; 24(2):322-5. View in: PubMed

Michail S, Bultron G, Depaolo RW. Genetic variants associated with Crohn's disease. Appl Clin Genet. 2013; 6:25-32. View in: PubMed

Rigsbee L, Agans R, Shankar V, Kenche H, Khamis HJ, Michail S, Paliy O. Quantitative profiling of gut microbiota of children with diarrhea-predominant irritable bowel syndrome. Am J Gastroenterol. 2012 Nov; 107(11):1740-51. View in: PubMed

Michail S, Durbin M, Turner D, Griffiths AM, Mack DR, Hyams J, Leleiko N, Kenche H, Stolfi A, Wine E. Alterations in the gut microbiome of children with severe ulcerative colitis. Inflamm Bowel Dis. 2012 Oct; 18(10):1799-808. View in: PubMed

Kosmadakis G, Pappas P, Gobou A, Smirloglou D, Michail S. Severe upper extremity polyneuropathy due to inferior brachial plexus compression as a result of left subclavian artery pseudoaneurysm. Saudi J Kidney Dis Transpl. 2012 Sep; 23(5):1028-31. View in: PubMed

Michail S, Ramsy M, Soliman E. Advances in inflammatory bowel diseases in children. Minerva Pediatr. 2012 Jun; 64(3):257-70. View in: PubMed

Kosmadakis G, Smirloglou D, Gobou A, Draganis T, Michail S. End-stage renal disease due to hydronephrosis in a patient with artificial urinary sphincter. Int J Artif Organs. 2011 Nov; 34(11):1106-8. View in: PubMed

Agans R, Rigsbee L, Kenche H, Michail S, Khamis HJ, Paliy O. Distal gut microbiota of adolescent children is different from that of adults. FEMS Microbiol Ecol. 2011 Aug; 77(2):404-12. View in: PubMed

Kosmadakis G, Michail O, Filiopoulos V, Papadopoulou P, Michail S. Acute kidney injury due to rhabdomyolysis in narcotic drug users. Int J Artif Organs. 2011 Jul; 34(7):584-8. View in: PubMed

Hyams JS, Lerer T, Mack D, Bousvaros A, Griffiths A, Rosh J, Otley A, Evans J, Stephens M, Kay M, Keljo D, Pfefferkorn M, Saeed S, Crandall W, Michail S, Kappelman MD, Grossman A, Samson C, Sudel B, Oliva-Hemker M, Leleiko N, Markowitz J. Outcome following thiopurine use in children with ulcerative colitis: a prospective multicenter registry study. Am J Gastroenterol. 2011 May; 106(5):981-7. View in: PubMed

Michail S, Kenche H. Gut microbiota is not modified by Randomized, Double-blind, Placebo-controlled Trial of VSL#3 in Diarrhea-predominant Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2011 Mar; 3(1):1-7. View in: PubMed

Kosmadakis G, Filiopoulos V, Georgoulias C, Tentolouris N, Michail S. Comparison of the influence of angiotensin-converting enzyme inhibitor lisinopril and angiotensin II receptor antagonist losartan in patients with idiopathic membranous nephropathy and nephrotic syndrome. Scand J Urol Nephrol. 2010 Sep; 44(4):251-6. View in: PubMed

Tschudy J, Michail S. Disseminated histoplasmosis and pneumocystis pneumonia in a child with Crohn disease receiving infliximab. J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):221-2. View in: PubMed

Kosmadakis G, Georgoulias C, Filiopoulos V, Stefanou I, Smirloglou D, Michail S. Lethal Strongyloides stercoralis superinfection in an immunocompromised patient. Ren Fail. 2010 Jul; 32(6):750-2. View in: PubMed

Kosmadakis G, Filiopoulos V, Smirloglou D, Skarlas P, Georgoulias C, Michail S. Comparison of immunosuppressive therapeutic regimens in patients with nephrotic syndrome due to idiopathic membranous nephropathy. Ren Fail. 2010 Jun; 32(5):566-71. View in: PubMed

Kosmadakis G, Filiopoulos V, Georgoulias C, Smirloglou D, Draganis T, Michail S. Quantitative evaluation of proteinuria by estimation of the protein/creatinine ratio in a random urine sample. Ren Fail. 2010 Jan; 32(2):153-6. View in: PubMed

Michail S. The role of probiotics in allergic diseases. Allergy Asthma Clin Immunol. 2009 Dec; 5(1):5. View in: PubMed

Kosmadakis G, Viskaduraki M, Michail S. The validity of fractional excretion of uric acid in the diagnosis of acute kidney injury due to decreased kidney perfusion. Am J Kidney Dis. 2009 Dec; 54(6):1186-7. View in: PubMed

Paliy O, Kenche H, Abernathy F, Michail S. High-throughput quantitative analysis of the human intestinal microbiota with a phylogenetic microarray. Appl Environ Microbiol. 2009 Jun; 75(11):3572-9. View in: PubMed

Kibria R, Michail S, Ali SA. Rapunzel syndrome-a rare cause of multiple jejunal intussusception. South Med J. 2009 Apr; 102(4):416-8. View in: PubMed

Michail SK, Stolfi A, Johnson T, Onady GM. Efficacy of probiotics in the treatment of pediatric atopic dermatitis: a meta-analysis of randomized controlled trials. Ann Allergy Asthma Immunol. 2008 Nov; 101(5):508-16. View in: PubMed

Carvalho RS, Michail S, Ashai-Khan F, Mezoff AG. An update on pediatric gastroenterology and nutrition: a review of some recent advances. Curr Probl Pediatr Adolesc Health Care. 2008 Aug; 38(7):204-28. View in: PubMed

Michail S, Nanagas V, Mezoff AG. An unusual cause of postfundoplication vomiting. J Pediatr Surg. 2008 Mar; 43(3):E45-7. View in: PubMed

Michail S. Gastroesophageal reflux. Pediatr Rev. 2007 Mar; 28(3):101-10. View in: PubMed

Nakopoulou L, Lazaris AC, Boletis I, Michail S, Iatrou C, Papadakis G, Athanassiadou S, Stathakis C. The expression of matrix metalloproteinase-11 protein in various types of glomerulonephritis. Nephrol Dial Transplant. 2007 Jan; 22(1):109-17. View in: PubMed

Clinical efficacy of probiotics: review of the evidence with focus on children. J Pediatr Gastroenterol Nutr. 2006 Oct; 43(4):550-7. View in: PubMed

Preud'Homme DL, Michail S, Hodges C, Milliken T, Mezoff AG. Use of wireless capsule endoscopy in the management of severe Henoch-Schonlein purpura. Pediatrics. 2006 Sep; 118(3):e904-6. View in: PubMed

Voskaridou E, Terpos E, Michail S, Hantzi E, Anagnostopoulos A, Margeli A, Simirloglou D, Loukopoulos D, Papassotiriou I. Early markers of renal dysfunction in patients with sickle cell/beta-thalassemia. Kidney Int. 2006 Jun; 69(11):2037-42. View in: PubMed

Mezoff A, Prued'Homme D, Hodges C, Milliken T, Michail S. Capsule endoscopy in pediatric patients with hamartomatous polyp syndromes. J Pediatr Gastroenterol Nutr. 2006 Feb; 42(2):240-2. View in: PubMed

Pappas P, Leonardou P, Papadoukakis S, Zavos G, Michail S, Boletis J, Tzortzis G. Urgent superselective segmental renal artery embolization in the treatment of life-threatening renal hemorrhage. Urol Int. 2006; 77(1):34-41. View in: PubMed

Michail S, Mezoff E, Abernathy F. Role of selectins in the intestinal epithelial migration of eosinophils. Pediatr Res. 2005 Oct; 58(4):644-7. View in: PubMed

Bausserman M, Michail S. The use of Lactobacillus GG in irritable bowel syndrome in children: a double-blind randomized control trial. J Pediatr. 2005 Aug; 147(2):197-201. View in: PubMed

Michail S, Gendy E, Preud'Homme D, Mezoff A. Polyethylene glycol for constipation in children younger than eighteen months old. J Pediatr Gastroenterol Nutr. 2004 Aug; 39(2):197-9. View in: PubMed

Michail S, Abernathy F. A new model for studying eosinophil migration across cultured intestinal epithelial monolayers. J Pediatr Gastroenterol Nutr. 2004 Jul; 39(1):56-63. View in: PubMed

Politou M, Tsaftarides P, Vassiliades J, Siakantaris MP, Michail S, Nakopoulou L, Pangalis GA, Vaiopoulos G. Thrombotic microangiopathy in a patient with Sezary syndrome treated with interferon-alpha. Nephrol Dial Transplant. 2004 Mar; 19(3):733-5. View in: PubMed

Michail S, Abernathy F. Lactobacillus plantarum inhibits the intestinal epithelial migration of neutrophils induced by enteropathogenic Escherichia coli. J Pediatr Gastroenterol Nutr. 2003 Mar; 36(3):385-91. View in: PubMed

Michail SK, Halm DR, Abernathy F. Enteropathogenic Escherichia coli: stimulating neutrophil migration across a cultured intestinal epithelium without altering transepithelial conductance. J Pediatr Gastroenterol Nutr. 2003 Feb; 36(2):253-60. View in: PubMed

Michail S, Stathakis Ch, Marinaki S, Revenas C, Nakopoulou L, Vaiopoulos G. Relapse of predominant tubulointerstitial lupus nephritis. Lupus. 2003; 12(9):728-9. View in: PubMed

Michail S, Broxon E, Mezoff A, Preud'homme D, Hitch D. A rare rectal tumor presenting with encopresis and rectal bleeding in a three-year-old girl: case report and review of the literature. J Pediatr Gastroenterol Nutr. 2002 Oct; 35(4):580-2. View in: PubMed

Michail S, Abernathy F. Lactobacillus plantarum reduces the in vitro secretory response of intestinal epithelial cells to enteropathogenic Escherichia coli infection. J Pediatr Gastroenterol Nutr. 2002 Sep; 35(3):350-5. View in: PubMed

Nakopoulou L, Lazaris ACh, Boletis IN, Michail S, Giannopoulou I, Zeis PM, Stathakis CP, Davaris PS. Evaluation of E-cadherin/catenin complex in primary and secondary glomerulonephritis. Am J Kidney Dis. 2002 Mar; 39(3):469-74. View in: PubMed

Michail S, Preud'Homme D, Christian J, Nanagas V, Goodwin C, Hitch D, Mezoff A. Laparoscopic cholecystectomy: effective treatment for chronic abdominal pain in children with acalculous biliary pain. J Pediatr Surg. 2001 Sep; 36(9):1394-6. View in: PubMed

Mack DR, Michail S, Wei S, McDougall L, Hollingsworth MA. Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression. Am J Physiol. 1999 Apr; 276(4 Pt 1):G941-50. View in: PubMed

Michail S, Stathakis C, Nakopoulou L, Aroni K, Revenas K, Avdikou K, Vaiopoulos G. Acute renal failure in an adult patient with Henoch-Schoenlein purpura after episode of macroscopic hematuria. Ren Fail. 1999 Jan; 21(1):107-11. View in: PubMed

Michail S, Collins JF, Xu H, Kaufman S, Vanderhoof J, Ghishan FK. Abnormal expression of brush-border membrane transporters in the duodenal mucosa of two patients with microvillus inclusion disease. J Pediatr Gastroenterol Nutr. 1998 Nov; 27(5):536-42. View in: PubMed

Tzortzis G, Kolomodi D, Stathopoulou S, Kostakis A, Michail S, Pappas P, Revenas K. Hyperselective renal artery embolisation in the treatment of post-traumatic iatrogenic haematuria: report of two cases. Int Angiol. 1998 Mar; 17(1):58-61. View in: PubMed

Michail S, Vaiopoulos G, Nakopoulou L, Revenas C, Aroni K, Karam P, Stathakis C, Thosios T. Henoch-Schoenlein purpura and acute interstitial nephritis after intravenous vancomycin administration in a patient with a staphylococcal infection. Scand J Rheumatol. 1998; 27(3):233-5. View in: PubMed

Michail S, Nakopoulou L, Stavrianopoulos I, Stamatiadis D, Avdikou K, Vaiopoulos G, Stathakis C. Acute renal failure associated with immunoglobulin administration. Nephrol Dial Transplant. 1997 Jul; 12(7):1497-9. View in: PubMed

Michail S, Mohammadpour M, Park JH, Vanderhoof JA. Soy-polysaccharide-supplemented soy formula enhances mucosal disaccharidase levels following massive small intestinal resection in rats. J Pediatr Gastroenterol Nutr. 1997 Feb; 24(2):140-5. View in: PubMed

Michail S, Dagounaki P, Stamatiadis D, Vaiopoulos G, Stathakis C, Vosnides G. A case of thyrotoxic hypokalaemic periodic paralysis in a Greek man. Nephrol Dial Transplant. 1996 Aug; 11(8):1634-6. View in: PubMed

Michail S, Mohammadpour H, Park JH, Vanderhoof JA. Effect of glutamine-supplemented elemental diet on mucosal adaptation following bowel resection in rats. J Pediatr Gastroenterol Nutr. 1995 Nov; 21(4):394-8. View in: PubMed

Stathakis C, Michail S, Agrafiotis A, Bristogiannis G, Katopodis K, Lagouranis A, Dimarogona K, Avlami A, Vosnides G. Septicaemia in chronic renal failure. J Chemother. 1989 Jul; 1(4 Suppl):835-8. View in: PubMed

Goldberg M, Michail S, Niswander D. An unusual source of error. Anesth Analg. 1985 Jun; 64(6):652. View in: PubMed

Michail S. [Therapeutic progress in glaucoma during the past 30 years]. Rev Chir Oncol Radiol O R L Oftalmol Stomatol Ser Oftalmol. 1975 Apr-Jun; 19(2):89-91. View in: PubMed

el-Rehim MA, Ibrahim IA, Michail SH, el-Meleigi MA. Serological relationships between Pythium irregulare Buisman and certain tomato cultivars. Zentralbl Bakteriol Parasitenkd Infektionskr Hyg. 1974; 129(1):179-82. View in: PubMed

Michail S, Karamanlidis AN. Trigeminothalamic fibre connexions in the dog and the pig. An experimental study with the retrograde cell degeneration method. J Anat. 1970 Nov; 107(Pt 3):557-66. View in: PubMed

Michail S. [Cryotherapy in a case of ocular acne rosacea]. Ann Ocul (Paris). 1970 Jul; 203(7):669-72. View in: PubMed

Michail S, Nuta M, Niculescu A. [Anatomo-pathological study of a case of ocular trauma caused by a chemical pencil]. Arch Ophtalmol Rev Gen Ophtalmol. 1970 Mar; 30(3):227-30. View in: PubMed

Michail S, Karamanlidis A. [Morphology of Auerbach's myenteric plexus of the small intestine of the dog]. Acta Anat (Basel). 1968; 67(3):424-36. View in: PubMed

MICHAIL S. [Giant orbital cystic teratoma with dental inclusion]. Arch Ophtalmol Rev Gen Ophtalmol. 1961 Oct-Nov; 21:675-85. View in: PubMed

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