Faculty

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Uri Elkayam, MD
Clinical Professor of Medicine (Part Time)
Medicine
IRD 331 Off Campus Los Angeles
+1 323 226 7541

Overview

Uri Elkayam, MD is a Professor of Medicine and a Professor of Obstetrics and Gynecology at the University of Southern California. He is a nationally and internationally known expert in heart failure and heart disease in pregnancy. Dr Elkayam is a past member of the executive council of the Heart Failure Society of America and the chairman of its corporate affairs committee. He is a present or past editorial board member of the Journal of the American College of Cardiology , American Journal of Cardiology, Journal of Cardiac Failure, Heart Failure, Heart Failure Reviews, Journal of Preventive Cardiology and Cardiology in Review.

Awards

International Academy of Cardiology: Distinguished Fellowship Award- Cardiology, 2007

Department of Maternal- Fetal Medicine, USC Women's & Children's Hospital : Award for Education of Residents and Fellows, 2002

8th World Congress on Heart Failure : Melvin L. Marcus Memorial Award for Distinguished Contribution as a Gifted Teacher, 2002

Publications

Myocardial Damage Detected by Late Gadolinium Enhancement Cardiac Magnetic Resonance Is Uncommon in Peripartum Cardiomyopathy. J Am Heart Assoc. 2017 Apr 03; 6(4). View in: PubMed

Heart Failure-Induced Brain Injury. J Am Coll Cardiol. 2017 Mar 28; 69(12):1609-1616. View in: PubMed

Pregnancy and the Risk of Spontaneous Coronary Artery Dissection: An Analysis of 120 Contemporary Cases. Circ Cardiovasc Interv. 2017 Mar; 10(3). View in: PubMed

Reply: CT Rather Than Invasive Angiography for Pregnant Patients With NSTEMI? More Delay and More Radiation. J Am Coll Cardiol. 2016 Dec 20; 68(24):2717-2718. View in: PubMed

Echocardiography in Pregnancy: Part 1. Curr Cardiol Rep. 2016 Sep; 18(9):92. View in: PubMed

Echocardiography in Pregnancy: Part 2. Curr Cardiol Rep. 2016 Sep; 18(9):90. View in: PubMed

Response by Arany and Elkayam to Letter Regarding Article, "Peripartum Cardiomyopathy". Circulation. 2016 Aug 16; 134(7):e83-4. View in: PubMed

High-Risk Cardiac Disease in Pregnancy: Part I. J Am Coll Cardiol. 2016 Jul 26; 68(4):396-410. View in: PubMed

High-Risk Cardiac Disease in Pregnancy: Part II. J Am Coll Cardiol. 2016 Jul 01. View in: PubMed

Relaxin for the Treatment of Acute Decompensated Heart Failure: Pharmacology, Mechanisms of Action, and Clinical Evidence. Cardiol Rev. 2016 Jul-Aug; 24(4):194-204. View in: PubMed

The Search for a Crystal Ball to Predict Early Recovery From Peripartum Cardiomyopathy? JACC Heart Fail. The Search for a Crystal Ball to Predict Early Recovery From Peripartum Cardiomyopathy? JACC Heart Fail. 2016 May; 4(5):389-91. View in: PubMed

Peripartum Cardiomyopathy. Circulation. 2016 Apr 5; 133(14):1397-409. View in: PubMed

GNB3 C825T Polymorphism and Myocardial Recovery in Peripartum Cardiomyopathy: Results of the Multicenter Investigations of Pregnancy-Associated Cardiomyopathy Study. Circ Heart Fail. 2016 Mar; 9(3):e002683. View in: PubMed

Reply: Comparison of the American PPCM Registry Data With International Registries. J Am Coll Cardiol. 2016 Feb 16; 67(6):734-5. View in: PubMed

Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies. N Engl J Med. 2016 Jan 21; 374(3):233-41. View in: PubMed

Clinical Outcomes for Peripartum Cardiomyopathy in North America: Results of the IPAC Study (Investigations of Pregnancy-Associated Cardiomyopathy). J Am Coll Cardiol. 2015 Aug 25; 66(8):905-14. View in: PubMed

"Of mice and (wo)men": The need to confirm results of animal experimentations with solid clinical data. Trends Cardiovasc Med. 2015 Aug; 25(6):505-7. View in: PubMed

Cardiorenal interactions in acute decompensated heart failure: contemporary concepts facing emerging controversies. J Card Fail. 2014 Dec; 20(12):1004-11. View in: PubMed

Cardiac medication during pregnancy, data from the ROPAC. Int J Cardiol. 2014 Nov 15; 177(1):124-8. View in: PubMed

Risk of subsequent pregnancy in women with a history of peripartum cardiomyopathy. J Am Coll Cardiol. 2014 Oct 14; 64(15):1629-36. View in: PubMed

Monitoring of anti-xa in pregnant patients with mechanical prosthetic valves receiving low-molecular-weight heparin: peak or trough levels? J Cardiovasc Pharmacol Ther. Monitoring of anti-xa in pregnant patients with mechanical prosthetic valves receiving low-molecular-weight heparin: peak or trough levels? J Cardiovasc Pharmacol Ther. 2014 Sep; 19(5):451-6. View in: PubMed

Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial. Am J Cardiol. 2014 Jul 1; 114(1):151-9. View in: PubMed

EURObservational Research Programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM. Eur J Heart Fail. 2014 May; 16(5):583-91. View in: PubMed

Pregnancy-associated acute myocardial infarction: a review of contemporary experience in 150 cases between 2006 and 2011. Circulation. 2014 Apr 22; 129(16):1695-702. View in: PubMed

Some more on preventing congenital heart block. Autoimmun Rev. 2014 Jan; 13(1):73-4. View in: PubMed

Association of hyponatremia to diuretic response and incidence of increased serum creatinine levels in hospitalized patients with acute decompensated heart failure. Cardiology. 2014; 128(4):333-42. View in: PubMed

Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: a review of published literature and registered clinical trials. Autoimmun Rev. 2013 Sep; 12(11):1039-45. View in: PubMed

Effect of Amlodipine on the Survival of Patients With Severe Chronic Heart Failure Due to a Nonischemic Cardiomyopathy: Results of the PRAISE-2 Study (Prospective Randomized Amlodipine Survival Evaluation 2). JACC Heart Fail. 2013 Aug; 1(4):308-14. View in: PubMed

Mechanical heart valve thrombosis in pregnancy. J Heart Valve Dis. 2013 Jul; 22(4):603-6. View in: PubMed

Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure. J Cardiovasc Pharmacol Ther. 2013 Jul; 18(4):345-53. View in: PubMed

Differences in clinical profile of African-American women with peripartum cardiomyopathy in the United States. J Card Fail. 2013 Apr; 19(4):214-8. View in: PubMed

Cardiovascular imaging of the pregnant patient. AJR Am J Roentgenol. 2013 Mar; 200(3):515-21. View in: PubMed

Clinical experience with low-dose continuous infusion of furosemide in acute heart failure: assessment of efficacy and safety. J Cardiovasc Pharmacol Ther. 2012 Dec; 17(4):373-81. View in: PubMed

Physiologic changes during normal pregnancy and delivery. Cardiol Clin. 2012 Aug; 30(3):317-29. View in: PubMed

Cardiovascular drugs in pregnancy. Cardiol Clin. 2012 Aug; 30(3):463-91. View in: PubMed

Peripartum cardiomyopathy. Cardiol Clin. 2012 Aug; 30(3):435-40. View in: PubMed

Anticoagulation in pregnancy. Cardiol Clin. 2012 Aug; 30(3):395-405. View in: PubMed

Cardiovascular disease in pregnancy. Cardiol Clin. 2012 Aug; 30(3):xi-xii. View in: PubMed

Serial echocardiographic assessment of the human heart in normal pregnancy. Circ Cardiovasc Imaging. 2012 May 1; 5(3):283-5. View in: PubMed

The search for a safe and effective anticoagulation regimen in pregnant women with mechanical prosthetic heart valves. J Am Coll Cardiol. 2012 Mar 20; 59(12):1116-8. View in: PubMed

Comparative Effects of Nesiritide and Nitroglycerin on Renal Function, and Incidence of Renal Injury by Traditional and RIFLE Criteria in Acute Heart Failure. J Cardiovasc Pharmacol Ther. 2012 Mar; 17(1):79-85. View in: PubMed

Clinical characteristics of peripartum cardiomyopathy in the United States: diagnosis, prognosis, and management. J Am Coll Cardiol. 2011 Aug 9; 58(7):659-70. View in: PubMed

Evaluation of the clinical relevance of baseline left ventricular ejection fraction as a predictor of recovery or persistence of severe dysfunction in women in the United States with peripartum cardiomyopathy. J Card Fail. 2011 May; 17(5):426-30. View in: PubMed

Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy. Eur J Heart Fail. 2010 Aug; 12(8):767-78. View in: PubMed

Comparison of pioglitazone vs glyburide in early heart failure: insights from a randomized controlled study of patients with type 2 diabetes and mild cardiac disease. Congest Heart Fail. 2010 May-Jun; 16(3):111-7. View in: PubMed

Bromocriptine for the treatment of peripartum cardiomyopathy. Circulation. 2010 Apr 6; 121(13):1463-4. View in: PubMed

Favorable outcome of pregnancy with an elective use of epoprostenol and sildenafil in women with severe pulmonary hypertension. Cardiology. 2010; 115(3):205-8. View in: PubMed

Venous thromboembolism in hospitalized patients with heart failure: incidence, prognosis, and prevention. Circ Heart Fail. 2010 Jan; 3(1):165-73. View in: PubMed

Cardiomyopathy: the importance of recognizing the uncommon diagnosis. Prog Cardiovasc Dis. 2010 Jan-Feb; 52(4):262-3. View in: PubMed

Left ventricular noncompaction. Prog Cardiovasc Dis. 2010 Jan-Feb; 52(4):264-73. View in: PubMed

Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials. Eur Heart J. 2009 Dec; 30(24):3015-26. View in: PubMed

Pregnancy in Marfan syndrome: maternal and fetal risk and recommendations for patient assessment and management. Cardiol Rev. 2009 Nov-Dec; 17(6):253-62. View in: PubMed

Clinical profile and predictors of complications in peripartum cardiomyopathy. J Card Fail. 2009 Oct; 15(8):645-50. View in: PubMed

Longitudinal changes in the B-type natriuretic peptide levels in normal pregnancy and postpartum. Clin Cardiol. 2009 Aug; 32(8):E60-2. View in: PubMed

Beta-blockers in the treatment of aortic regurgitation a new opportunity? J Am Coll Cardiol. Beta-blockers in the treatment of aortic regurgitation a new opportunity? J Am Coll Cardiol. 2009 Jul 28; 54(5):458-9. View in: PubMed

Reduction in mitral regurgitation during therapy guided by measured filling pressures in the ESCAPE trial. Circ Heart Fail. 2009 May; 2(3):181-8. View in: PubMed

Impact of acute serum creatinine elevation in patients treated with nesiritide. Clin Cardiol. 2009 Apr; 32(4):215-9. View in: PubMed

Peripartum cardiomyopathy, an autoimmune manifestation of allograft rejection? Autoimmun Rev. Peripartum cardiomyopathy, an autoimmune manifestation of allograft rejection? Autoimmun Rev. 2009 Mar; 8(5):384-7. View in: PubMed

Cardiovascular problems in pregnant women with marfan syndrome. Circulation. 2009 Feb 3; 119(4):619-23. View in: PubMed

Assessment of renal hemodynamic effects of nesiritide in patients with heart failure using intravascular Doppler and quantitative angiography. JACC Cardiovasc Imaging. 2008 Nov; 1(6):765-71. View in: PubMed

Cheyne-Stokes respiration and cardiac hemodynamics in heart failure. Catheter Cardiovasc Interv. 2008 Oct 1; 72(4):581-5. View in: PubMed

Efficacy and safety of the vasopressin V1A/V2-receptor antagonist conivaptan in acute decompensated heart failure: a dose-ranging pilot study. J Card Fail. 2008 Oct; 14(8):641-7. View in: PubMed

Pioglitazone and heart failure: results from a controlled study in patients with type 2 diabetes mellitus and systolic dysfunction. J Card Fail. 2008 Aug; 14(6):445-52. View in: PubMed

Acute myocardial infarction associated with pregnancy. J Am Coll Cardiol. 2008 Jul 15; 52(3):171-80. View in: PubMed

Renal Vasodilatory Action of Dopamine in Patients With Heart Failure: Magnitude of Effect and Site of Action. Circulation. 2008 Jan 15; 117(2):200-205. View in: PubMed

Vasodilators in the management of acute heart failure. Crit Care Med. 2008 Jan; 36(1 Suppl):S95-105. View in: PubMed

Effect of pulmonary stenosis on pregnancy outcomes--a case-control study. Am Heart J. 2007 Nov; 154(5):852-4. View in: PubMed

The challenge of correcting volume overload in hospitalized patients with decompensated heart failure. J Am Coll Cardiol. 2007 Feb 13; 49(6):684-6. View in: PubMed

Use and impact of inotropes and vasodilator therapy in hospitalized patients with severe heart failure. Am Heart J. 2007 Jan; 153(1):98-104. View in: PubMed

Comparison of 60-day mortality in hospitalized heart failure patients with versus without hypothermia. Am J Cardiol. 2006 Dec 1; 98(11):1485-8. View in: PubMed

Variable response of conductance and resistance coronary arteries to endothelial stimulation in patients with heart failure due to nonischemic dilated cardiomyopathy. J Cardiovasc Pharmacol Ther. 2006 Sep; 11(3):197-202. View in: PubMed

Peripartum cardiomyopathy. Lancet. 2006 Aug 19; 368(9536):687-93. View in: PubMed

Safety of exercise testing in the chest pain unit: 31-mm ST elevation in variant angina. J Electrocardiol. 2006 Jul; 39(3):309. View in: PubMed

Effects of nitrates and hydralazine in heart failure: clinical evidence before the african american heart failure trial. Am J Cardiol. 2005 Oct 10; 96(7B):37i-43i. View in: PubMed

Valvular heart disease and pregnancy: part II: prosthetic valves. J Am Coll Cardiol. 2005 Aug 2; 46(3):403-10. View in: PubMed

Left atrial thrombosis in pregnant women with mitral stenosis and sinus rhythm. Am J Obstet Gynecol. 2005 Aug; 193(2):501-4. View in: PubMed

Valvular heart disease and pregnancy part I: native valves. J Am Coll Cardiol. 2005 Jul 19; 46(2):223-30. View in: PubMed

The clinical challenge of bridging anticoagulation with low-molecular-weight heparin in patients with mechanical prosthetic heart valves: an evidence-based comparative review focusing on anticoagulation options in pregnant and nonpregnant patients. Am Heart J. 2005 Jul; 150(1):27-34. View in: PubMed

Pregnancy-associated cardiomyopathy: clinical characteristics and a comparison between early and late presentation. Circulation. 2005 Apr 26; 111(16):2050-5. View in: PubMed

Letter regarding article by Wang et al, "nesiritide does not improve renal function in patients with chronic heart failure and worsening serum creatinine". Circulation. 2005 Apr 12; 111(14):e182-3; author reply e182-3. View in: PubMed

What resting heart rate should one aim for when treating patients with heart failure with a beta-blocker? Experiences from the Metoprolol Controlled Release/Extended Release Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF). J Am Coll Cardiol. 2005 Jan 18; 45(2):252-9. View in: PubMed

Survey of the use of organic nitrates for the treatment of chronic congestive heart failure in the United States. Am J Cardiol. 2004 Dec 1; 94(11):1465-8. View in: PubMed

Intravenous nitroglycerin in the treatment of decompensated heart failure: potential benefits and limitations. J Cardiovasc Pharmacol Ther. 2004 Dec; 9(4):227-41. View in: PubMed

Effect of elevated admission serum creatinine and its worsening on outcome in hospitalized patients with decompensated heart failure. Am J Cardiol. 2004 Oct 1; 94(7):957-60. View in: PubMed

Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation. Cardiol Rev. 2004 Sep-Oct; 12(5):240-61. View in: PubMed

Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation. Cardiol Rev. 2004 Jul-Aug; 12(4):201-21. View in: PubMed

Anticoagulation in pregnant women with prosthetic heart valves. J Cardiovasc Pharmacol Ther. 2004 Jun; 9(2):107-15. View in: PubMed

Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial. JAMA. 2004 Apr 28; 291(16):1963-71. View in: PubMed

Comparison of effects on left ventricular filling pressure of intravenous nesiritide and high-dose nitroglycerin in patients with decompensated heart failure. Am J Cardiol. 2004 Jan 15; 93(2):237-40. View in: PubMed

Evaluation of myocardial blood flow reserve in patients with chronic congestive heart failure due to idiopathic dilated cardiomyopathy. Am J Cardiol. 2003 Nov 15; 92(10):1246-9. View in: PubMed

Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure. J Am Coll Cardiol. 2003 Jul 2; 42(1):140-7. View in: PubMed

Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure. Am Heart J. 2003 Feb; 145(2 Suppl):S51-4. View in: PubMed

Effect of nesiritide (B-type natriuretic peptide) and dobutamine on ventricular arrhythmias in the treatment of patients with acutely decompensated congestive heart failure: the PRECEDENT study. Am Heart J. 2002 Dec; 144(6):1102-8. View in: PubMed

Nesiritide: a new drug for the treatment of decompensated heart failure. J Cardiovasc Pharmacol Ther. 2002 Jul; 7(3):181-94. View in: PubMed

Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failure. J Am Coll Cardiol. 2002 Mar 6; 39(5):798-803. View in: PubMed

Impaired endothelium-mediated vasodilation in heart failure: clinical evidence and the potential for therapy. J Card Fail. 2002 Feb; 8(1):15-20. View in: PubMed

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