Division of Gastrointestinal and Liver Diseases

Research

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The Division of Gastrointestinal and Liver Diseases published 52 peer-reviewed research papers during the period of January 1 through December 31, 2015, and nine more are in press. This body of work represents a broad range of clinical and basic research activities from nearly all of the division’s members.

Faculty Research Areas

  • Clinical and Endoscopic Management of Pancreatitis
    Gastrointestinal Malignancy
    Complex Biliary Disease
    Development of Biomarkers for Pancreatic and Gastric Cancer

  • Signaling Pathways Involved in Liver Cell Death
    Drug-Induced Liver Injury
    Acetaminophen Toxicity and Acute Liver Failure

  • Role of Liver Sinusoidal Endothelial Cell in Liver Injury Recovery and Liver Fibrosis
    Drug-Induced Liver Injury

  • Viral Hepatitis
    Liver Transplantation
    Complications of End Stage Liver Disease

  • Endoplasmic Reticulum (ER) Stress and Liver Disease
    Hyperhomocysteinemia
    Hepatotoxicity of HIV Drugs and Alcohol
    Tackling Alcohol Intoxication with Nanotechnology

  • Liver Transplantation
    Hepatocellular Carcinoma
    Acute Liver Failure
    Portal Hypertension

  • Drug Toxicity
    Signal Transduction
    Oxidative Stress
    Glutathione Metabolism
    Pathogenesis of Alcoholic Liver Disease
    Endoplasmic Reticulum (ER) Stress
    Mitochondrial Biogenesis

  • Hepatitis C Treatment
    Liver Transplantation
    Cirrhotic Cardiomyopathy

  • Liver Transplantation
    Treatment of Hepatitis C Virus
    Acute Liver Failure
    Complications of Portal Hypertension

  • Diagnosis and Endoscopic Management of Complex Biliary and Pancreatic Disorders
    Endoscopic Ultrasound for Evaluation of Pancreatic Cysts and Malignancies
    Endoscopic Mucosal Resection and Large Colonic Polyps

  • Molecular Virology of Hepatitis C Virus
    Intrahepatic Innate Immunity against Hepatitis Virus
    Interferon Biology
    Synergism between Metabolic Liver Disease and Viral Hepatitis

    Lab site: https://sites.usc.edu/saito-lab/

  • Epithelial-Stromal Interactions in GI Tract Injury, Repair and Carcinogenesis

  • Health Maintenance in Inflammatory Bowel Disease
    Pregnancy in Inflammatory Bowel Disease
    Management of Variceal and Tumor Bleeding

  • Motility Disorders of the GI Tract

  • Gene Regulation by Oxidant Stress
    Dysregulation of Androgen Metabolism in Prostate Cancer
    Drug-Induced Liver Injury/Alcoholic Hepatitis and NAFLD

  • Mitochondrial Biogenesis in Liver Diseases
    Signal Transduction across Mitochondrial Membrane

  • Diagnosis and Treatment of Pancreatic, Esophageal, Gastric and Colorectal Cancers
    Advanced Endoscopic Management of Pancreatic Cysts, Large Common Bile Duct Stones, Complex Biliary Strictures and Large Colonic Polyps

  • Signal Transduction in Drug-Induced Hepatotoxicity, Non-Alcoholic Steatohepatitis and Alcoholic Hepatitis
    Identification of Therapeutic Target to Prevent Drug-Induced Hepatotoxicity
    Mitochondrial Biogenesis
    Oxidative Stress

    Students’ research program

  • Liver Transplantation
    Complications of Cirrhosis
    Drug-Induced Liver Injury
    Autoimmune Hepatitis
    Non-Alcoholic Steatohepatitis
    Alcoholic Liver Diseases