The Division of Gastrointestinal and Liver Diseases published 52 peer-reviewed research papers during the period of January 1 through December 31, 2015, and nine more are in press. This body of work represents a broad range of clinical and basic research activities from nearly all of the division’s members.

Faculty Research Areas

  • Clinical and Endoscopic Management of Pancreatitis
    Gastrointestinal Malignancy
    Complex Biliary Disease
    Development of Biomarkers for Pancreatic and Gastric Cancer

  • Signaling Pathways Involved in Liver Cell Death
    Drug-Induced Liver Injury
    Acetaminophen Toxicity and Acute Liver Failure

  • Role of Liver Sinusoidal Endothelial Cell in Liver Injury Recovery and Liver Fibrosis
    Drug-Induced Liver Injury

  • Liver Transplantation
    Hepatocellular Carcinoma
    Complications of Portal Hypertension

  • Complications of End-Stage Liver Diseases and Liver Transplantation
    Treatment of Chronic Viral Hepatitis

  • Viral Hepatitis
    Liver Transplantation
    Complications of End Stage Liver Disease

  • Novel Therapeutics and Diagnostics in Inflammatory Bowel Disease (IBD)
    Nutritional Monitoring and Interventions in IBD, Microscopic Colitis and Celiac Disease
    Issues of Adherence and Disparities in IBD
    Colon Cancer Surveillance in IBD

  • Gastrointestinal Cancer Screening and Prevention
    Diagnosis and Management of Hereditary/Familial Cancer Syndromes
    Cancer Epidemiology and Genetics, Endoscopic Screening, Chemoprevention

  • Endoplasmic Reticulum (ER) Stress and Liver Disease
    Hyperhomocysteinemia
    Hepatotoxicity of HIV Drugs and Alcohol
    Tackling Alcohol Intoxication with Nanotechnology

  • Liver Transplantation
    Hepatocellular Carcinoma
    Acute Liver Failure
    Portal Hypertension

  • Drug Toxicity
    Signal Transduction
    Oxidative Stress
    Glutathione Metabolism
    Pathogenesis of Alcoholic Liver Disease
    Endoplasmic Reticulum (ER) Stress
    Mitochondrial Biogenesis

  • Drug Toxicity
    Signal Transduction
    Oxidative Stress
    Glutathione Metabolism
    Pathogenesis of Alcoholic Liver Disease
    Endoplasmic Reticulum (ER) Stress
    Mitochondrial Biogenesis

  • Hepatitis C Treatment
    Liver Transplantation
    Cirrhotic Cardiomyopathy

  • Liver Transplantation
    Treatment of Hepatitis C Virus
    Acute Liver Failure
    Complications of Portal Hypertension

  • Foregut Disorders
    Treatment of Barrett’s Esophagus with EMR and Barrx Radiofrequency
    Esophageal Chest Pain
    Motor Disorders
    Deep Enteroscopy Using the Spirus Technique

  • Function of Liver NK and NKT Cells
    Liver Immunology and Diseases
    Innate Immunity in Drug-Induced Hepatotoxicity

  • Methylation and Trans-Sulfuration Pathways
    Tracer-Kinetics and Mathematical Modeling-Simulation

  • Diagnosis and Endoscopic Management of Complex Biliary and Pancreatic Disorders
    Endoscopic Ultrasound for Evaluation of Pancreatic Cysts and Malignancies
    Endoscopic Mucosal Resection and Large Colonic Polyps

  • Molecular Virology of Hepatitis C Virus
    Intrahepatic Innate Immunity against Hepatitis Virus
    Interferon Biology
    Synergism between Metabolic Liver Disease and Viral Hepatitis

    Lab site: https://sites.usc.edu/saito-lab/

  • Epithelial-Stromal Interactions in GI Tract Injury, Repair and Carcinogenesis

  • Health Maintenance in Inflammatory Bowel Disease
    Pregnancy in Inflammatory Bowel Disease
    Management of Variceal and Tumor Bleeding

  • Mechanisms of Cell Death in the Intestine
    Enterocyte Signal Transduction
    Pathogenesis of Inflammatory Bowel Disease
    Mucosal Immunology
    Intestinal Epithelial Cells
    Colorectal Cancer

  • Motility Disorders of the GI Tract

  • Gene Regulation by Oxidant Stress
    Dysregulation of Androgen Metabolism in Prostate Cancer
    Drug-Induced Liver Injury/Alcoholic Hepatitis and NAFLD

  • Mitochondrial Biogenesis in Liver Diseases
    Signal Transduction across Mitochondrial Membrane

  • Diagnosis and Treatment of Pancreatic, Esophageal, Gastric and Colorectal Cancers
    Advanced Endoscopic Management of Pancreatic Cysts, Large Common Bile Duct Stones, Complex Biliary Strictures and Large Colonic Polyps

  • Signal Transduction in Drug-Induced Hepatotoxicity, Non-Alcoholic Steatohepatitis and Alcoholic Hepatitis
    Identification of Therapeutic Target to Prevent Drug-Induced Hepatotoxicity
    Mitochondrial Biogenesis
    Oxidative Stress

    Students’ research program

  • Liver Transplantation
    Complications of Cirrhosis
    Drug-Induced Liver Injury
    Autoimmune Hepatitis
    Non-Alcoholic Steatohepatitis
    Alcoholic Liver Diseases

  • Risk Profile for Colon Cancer on Sigmoidoscopy and Colonoscopy
    Demographics and Inflammatory Bowel Disease