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Jianfu Chen

Associate Professor

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Email jianfu@usc.edu
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Publications

  • Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice. J Vis Exp. 2024 Sep 13; (211).. View in PubMed
  • Ribosome biogenesis controls cranial suture MSC fate via the complement pathway in mouse and human iPSC models. Stem Cell Reports. 2023 12 12; 18(12):2370-2385.. View in PubMed
  • Brain methylome remodeling selectively regulates neuronal activity genes linking to emotional behaviors in mice exposed to maternal immune activation. Nat Commun. 2023 11 29; 14(1):7829.. View in PubMed
  • Skull progenitor cell-driven meningeal lymphatic restoration improves neurocognitive functions in craniosynostosis. Cell Stem Cell. 2023 11 02; 30(11):1472-1485.e7.. View in PubMed
  • Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors. Nat Commun. 2019 06 13; 10(1):2612.. View in PubMed
  • Lin28-mediated temporal promotion of protein synthesis is crucial for neural progenitor cell maintenance and brain development in mice. Development. 2019 05 28; 146(10).. View in PubMed
  • C9orf72 deficiency promotes motor deficits of a C9ALS/FTD mouse model in a dose-dependent manner. Acta Neuropathol Commun. 2019 03 04; 7(1):32.. View in PubMed
  • Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult. J Vis Exp. 2018 04 26; (134).. View in PubMed
  • The African Zika virus MR-766 is more virulent and causes more severe brain damage than current Asian lineage and dengue virus. Development. 2017 11 15; 144(22):4114-4124.. View in PubMed
  • Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage. Development. 2016 11 15; 143(22):4127-4136.. View in PubMed
  • A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. Sci Adv. 2016 09; 2(9):e1601167.. View in PubMed
  • MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. Dev Biol. 2015 Dec 01; 408(1):140-50.. View in PubMed
  • Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 01; 142(9):1616-27.. View in PubMed
  • Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014 May 30; 5:3885.. View in PubMed
  • A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Dev Neurobiol. 2014 May; 74(5):483-97.. View in PubMed
  • The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15; 26(8):803-15.. View in PubMed
  • CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res. 2012 Mar 16; 110(6):818-30.. View in PubMed
  • The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly. J Cell Biol. 2011 Aug 22; 194(4):551-65.. View in PubMed
  • Transgenic overexpression of miR-133a in skeletal muscle. BMC Musculoskelet Disord. 2011 May 26; 12:115.. View in PubMed
  • Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2575-86.. View in PubMed
  • microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol. 2010 Sep 06; 190(5):867-79.. View in PubMed
  • MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep; 119(9):2772-86.. View in PubMed
  • microRNAs and muscle disorders. J Cell Sci. 2009 Jan 01; 122(Pt 1):13-20.. View in PubMed
  • Myocardin marks the earliest cardiac gene expression and plays an important role in heart development. Anat Rec (Hoboken). 2008 Oct; 291(10):1200-11.. View in PubMed
  • Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):2111-6.. View in PubMed
  • Muscling through the microRNA world. Exp Biol Med (Maywood). 2008 Feb; 233(2):131-8.. View in PubMed
  • Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol. 2007 Jun; 42(6):1137-41.. View in PubMed
  • MicroRNAs in skeletal and cardiac muscle development. DNA Cell Biol. 2007 Apr; 26(4):219-25.. View in PubMed
  • The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006 Feb; 38(2):228-33.. View in PubMed
  • The HopPtoF locus of Pseudomonas syringae pv. tomato DC3000 encodes a type III chaperone and a cognate effector. Mol Plant Microbe Interact. 2004 May; 17(5):447-55.. View in PubMed

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