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Maria Teresa Ochoa, MD

Professor of Clinical Dermatology

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Phone +1 323 442 6200
Email mariatoc@usc.edu
CTSI Profile

Overview

Dr. Ochoa is an Associate Clinical Professor of Dermatology at the Keck School of Medicine USC. She recently joined the Department of Dermatology at Keck Medicine of USC after 10 years of practice at the UCLA Division of Dermatology.

Dr. Ochoa is a member of the American Academy of Dermatology, the Society for Investigative Dermatology and California Dermatologic Society. Dr. Ochoa sees patients in the private practice settings at Keck Medicine of USC – Beverly Hills, and Healthcare Consultation Center II on the USC Health Sciences Campus, and participates in the care of the uninsured at the LAC+USC Medical Center. She serves as the Director of the Hansen’s clinic.

Dr. Ochoa provides dermatology services for the diagnosis and treatment of a broad range of general skin diseases such as acne, eczema, skin cancer and psoriasis, among others. Her clinical and research interest center around infectious diseases of the skin, including the diagnosis and treatment of patients with skin manifestations of HIV, tropical dermatology (skin infectious diseases acquired abroad) and sexually transmitted diseases.

Dr. Ochoa has a special research interest in the immunologic mechanism of the host response in infectious diseases of the skin.

Publications

  • More on Autochthonous Leprosy in the United StatesReply. N Engl J Med. 2023 Sep 07; 389(10):963-964. . View in PubMed
  • Impact of Mycobacterium leprae and Mycobacterium lepromatosis on immune reactions and clinical outcomes in Hansen’s disease: A single-center retrospective analysis J Am Acad Dermatol. 2023 Mar; 88(3):722-724. . View in PubMed
  • Mpox (Monkeypox) Clinical Pearls Cutis. 2023 04; 111(4):170-171. . View in PubMed
  • Editorial: Strategies Played by Immune Cells and Mycobacteria in the Battle Between Antimicrobial Activity and Bacterial Survival Front Immunol. 2022; 13:869692. . View in PubMed
  • Diffuse cutaneous leishmaniasis and HIV co-infection: A case report and review of the literature J Cutan Pathol. 2021 Jun; 48(6):802-806. . View in PubMed
  • The cellular architecture of the antimicrobial response network in human leprosy granulomas Nat Immunol. 2021 07; 22(7):839-850. . View in PubMed
  • Characterization and Outcomes of Patients With Hansen Disease Treated at the Los Angeles County Hospital JAMA Dermatol. 2019 Oct 01; 155(10):1190-1192. . View in PubMed
  • The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy PLoS Negl Trop Dis. 2019 07; 13(7):e0007589. . View in PubMed
  • IL-1ß Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells J Immunol. 2019 08 15; 203(4):911-921. . View in PubMed
  • Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria Sci Immunol. 2018 08 31; 3(26). . View in PubMed
  • IL-27 Suppresses Antimicrobial Activity in Human Leprosy J Invest Dermatol. 2015 Oct; 135(10):2410-2417. . View in PubMed
  • T lymphocyte density and distribution in human colorectal mucosa, and inefficiency of current cell isolation protocols PLoS One. 2015; 10(4):e0122723. . View in PubMed
  • Recognizing and managing the immunologic reactions in leprosy J Am Acad Dermatol. 2014 Oct; 71(4):795-803. . View in PubMed
  • Antigen-presenting cell candidates for HIV-1 transmission in human distal colonic mucosa defined by CD207 dendritic cells and CD209 macrophages AIDS Res Hum Retroviruses. 2014 Mar; 30(3):241-9. . View in PubMed
  • NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy Nat Med. 2012 Mar 25; 18(4):555-63. . View in PubMed
  • Mobile teledermatology: As doctors and patients are increasingly mobile, technology keeps us connected Skinmed. 2011 Jul-Aug; 9(4):231-8. . View in PubMed
  • New World cutaneous leishmaniasis: current challenges in diagnosis and parenteral treatment J Am Acad Dermatol. 2011 Mar; 64(3):587-92. . View in PubMed
  • A role for interleukin-5 in promoting increased immunoglobulin M at the site of disease in leprosy Immunology. 2010 Nov; 131(3):405-14. . View in PubMed
  • Interleukin-4 regulates the expression of CD209 and subsequent uptake of Mycobacterium leprae by Schwann cells in human leprosy Infect Immun. 2010 Nov; 78(11):4634-43. . View in PubMed
  • Human immunodeficiency virus and leishmaniasis J Glob Infect Dis. 2010 Sep; 2(3):248-57. . View in PubMed
  • Integrated pathways for neutrophil recruitment and inflammation in leprosy J Infect Dis. 2010 Feb 15; 201(4):558-69. . View in PubMed
  • Divergence of macrophage phagocytic and antimicrobial programs in leprosy Cell Host Microbe. 2009 Oct 22; 6(4):343-53. . View in PubMed
  • Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma Clin Cancer Res. 2009 Oct 01; 15(19):6267-76. . View in PubMed
  • “Dermal dendritic cells” comprise two distinct populations: CD1+ dendritic cells and CD209+ macrophages J Invest Dermatol. 2008 Sep; 128(9):2225-31. . View in PubMed
  • Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy J Clin Invest. 2008 Aug; 118(8):2917-28. . View in PubMed
  • LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells J Immunol. 2007 Dec 15; 179(12):8128-36. . View in PubMed
  • Activation of human CD4+ T cells by targeting MHC class II epitopes to endosomal compartments using human CD1 tail sequences Immunology. 2007 Dec; 122(4):522-31. . View in PubMed
  • Regulation of human T-cell homing receptor expression in cutaneous bacterial infection Immunology. 2007 Apr; 120(4):518-25. . View in PubMed
  • Functional characterization of a T-cell receptor BV6+ T-cell clone derived from a leprosy lesion Immunology. 2007 Mar; 120(3):354-61. . View in PubMed
  • Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens J Immunol. 2006 Aug 01; 177(3):1864-71. . View in PubMed
  • TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response J Immunol. 2006 Jul 01; 177(1):298-305. . View in PubMed
  • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response Science. 2006 Mar 24; 311(5768):1770-3. . View in PubMed
  • Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation J Immunol. 2006 Mar 15; 176(6):3536-47. . View in PubMed
  • TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells Nat Med. 2005 Jun; 11(6):653-60. . View in PubMed
  • Mohs’ micrographic surgery of a proliferating trichilemmal tumor in a young black man Dermatol Surg. 2005 Mar; 31(3):359-63. . View in PubMed
  • Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells J Clin Invest. 2004 Mar; 113(5):701-8. . View in PubMed
  • Use of genetic profiling in leprosy to discriminate clinical forms of the disease Science. 2003 Sep 12; 301(5639):1527-30. . View in PubMed
  • Activation and regulation of Toll-like receptors 2 and 1 in human leprosy Nat Med. 2003 May; 9(5):525-32. . View in PubMed
  • Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy Infect Immun. 2003 Mar; 71(3):1427-33. . View in PubMed
  • Distribution of Toll-like receptor 1 and Toll-like receptor 2 in human lymphoid tissue Immunology. 2003 Jan; 108(1):10-5. . View in PubMed
  • Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses J Immunol. 2002 Aug 01; 169(3):1535-41. . View in PubMed
  • Signaling lymphocytic activation molecule expression and regulation in human intracellular infection correlate with Th1 cytokine patterns J Immunol. 2001 Nov 15; 167(10):5719-24. . View in PubMed
  • Treatment failure in children in a randomized clinical trial with 10 and 20 days of meglumine antimonate for cutaneous leishmaniasis due to Leishmania viannia species Am J Trop Med Hyg. 2001 Mar-Apr; 64(3-4):187-93. . View in PubMed
  • Induction of direct antimicrobial activity through mammalian toll-like receptors Science. 2001 Feb 23; 291(5508):1544-7. . View in PubMed
  • T-cell release of granulysin contributes to host defense in leprosy Nat Med. 2001 Feb; 7(2):174-9. . View in PubMed
  • Role of granulysin in immunity to leprosy Lepr Rev. 2000 Dec; 71 Suppl:S115; discussion S115-6. . View in PubMed
  • Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10 J Immunol. 2000 Oct 01; 165(7):3804-10. . View in PubMed
  • Evidence for human CD4+ T cells in the CD1-restricted repertoire: derivation of mycobacteria-reactive T cells from leprosy lesions J Immunol. 2000 May 01; 164(9):4790-6. . View in PubMed
  • Positive IgG Western blot for Borrelia burgdorferi in Colombia Mem Inst Oswaldo Cruz. 1999 Jul-Aug; 94(4):499-503. . View in PubMed
  • IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection J Immunol. 1999 May 15; 162(10):6114-21. . View in PubMed
  • Mucosal leishmaniasis due to Leishmania (Viannia) panamensis in Colombia: clinical characteristics Am J Trop Med Hyg. 1998 Jul; 59(1):49-52. . View in PubMed
  • Treatment of cutaneous leishmaniasis in Colombia with dapsone Lancet. 1998 Feb 14; 351(9101):498-9. . View in PubMed
  • Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy Infect Immun. 1998 Feb; 66(2):499-504. . View in PubMed
  • Lepromatous and tuberculoid leprosy: clinical presentation and cytokine responses Int J Dermatol. 1996 Nov; 35(11):786-90. . View in PubMed
  • A yeast-derived antigen from Paracoccidioides brasiliensis useful for serologic testing Sabouraudia. 1985 Feb; 23(1):23-9. . View in PubMed

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