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Andrei Irimia, PhD

Associate Professor of Gerontology, Quantitative & Computational Biology, Biomedical Engineering, and Neuroscience

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Phone +1 213 740 1710
Email [email protected]
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Publications

  • Women’s reproductive factors predict local brain aging profiles mapped using deep neural networks. Geroscience. 2026 Mar 04.. View in PubMed
  • High Prevalence of Cerebrovascular Calcifications and Clinical Correlates in Indigenous Bolivian Forager-Horticulturalists: A Population-Based Observational Study. J Am Heart Assoc. 2026 Feb 03; 15(3):e043028.. View in PubMed
  • Investigating the Utility of Explainable Artificial Intelligence for Neuroimaging-Based Dementia Diagnosis and Prognosis. Hum Brain Mapp. 2026 Feb 01; 47(2):e70456.. View in PubMed
  • Graph Neural Network Reveals the Local Cortical Morphology of Brain Aging in Normal Cognition and Alzheimer’s Disease. ArXiv. 2026 Jan 23.. View in PubMed
  • Bridging mental health, cognition and the brain in mild traumatic brain injury: A multilayer network analysis of the TRACK-TBI study. Neuroimage Clin. 2026; 49:103957.. View in PubMed
  • Deep neural networks and genome-wide associations reveal the polygenic architecture of local brain aging. Geroscience. 2025 Dec 11.. View in PubMed
  • ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions. MethodsX. 2025 Dec; 15:103482.. View in PubMed
  • Physical activity mediates age differences in cognition among Tsimane forager-horticulturalists. J Gerontol A Biol Sci Med Sci. 2025 07 24; 80(8).. View in PubMed
  • Childhood skeletal lesions common in prehistory are present in living forager-farmers and predict adult markers of immune function. Sci Adv. 2025 Jul 18; 11(29):eadw3697.. View in PubMed
  • Linking Symptom Inventories Using Semantic Textual Similarity. J Neurotrauma. 2025 Jun; 42(11-12):1008-1020.. View in PubMed
  • Genetic Insights into Brain Morphology: a Genome-Wide Association Study of Cortical Thickness and T1-Weighted MRI Gray Matter-White Matter Intensity Contrast. Neuroinformatics. 2025 Apr 01; 23(2):26.. View in PubMed
  • Deep learning to quantify the pace of brain aging in relation to neurocognitive changes. Proc Natl Acad Sci U S A. 2025 Mar 11; 122(10):e2413442122.. View in PubMed
  • Explainable artificial intelligence for neuroimaging-based dementia diagnosis and prognosis. medRxiv. 2025 Feb 14.. View in PubMed
  • Neuroanatomical and clinical factors predicting future cognitive impairment. Geroscience. 2025 Feb; 47(1):915-934.. View in PubMed
  • FastSurfer parcellation accuracy after lesion filling in moderate-to-severe traumatic brain injury. Front Neurol. 2025; 16:1652385.. View in PubMed
  • Prediction of Post Traumatic Epilepsy Using MR-Based Imaging Markers. Hum Brain Mapp. 2024 Dec 01; 45(17):e70075.. View in PubMed
  • Anatomic Interpretability in Neuroimage Deep Learning: Saliency Approaches for Typical Aging and Traumatic Brain Injury. Res Sq. 2024 Oct 16.. View in PubMed
  • Neuroinformatics and Analysis of Traumatic Brain Injury and Related Conditions. Neuroinformatics. 2024 Oct; 22(4):569-572.. View in PubMed
  • Anatomic Interpretability in Neuroimage Deep Learning: Saliency Approaches for Typical Aging and Traumatic Brain Injury. Neuroinformatics. 2024 Oct; 22(4):591-606.. View in PubMed
  • Increases in regional brain volume across two native South American male populations. Geroscience. 2024 Oct; 46(5):4563-4583.. View in PubMed
  • Identification and Connectomic Profiling of Concussion Using Bayesian Machine Learning. J Neurotrauma. 2024 08; 41(15-16):1883-1900.. View in PubMed
  • Accelerated Aging after Traumatic Brain Injury: An ENIGMA Multi-Cohort Mega-Analysis. Ann Neurol. 2024 Aug; 96(2):365-377.. View in PubMed
  • Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis. Brain Sci. 2024 Jun 29; 14(7).. View in PubMed
  • Poor Oral Health Is Associated With Inflammation, Aortic Valve Calcification, and Brain Volume Among Forager-Farmers. J Gerontol A Biol Sci Med Sci. 2024 05 01; 79(5).. View in PubMed
  • Flow Characterization in a Partially Liquefied Vitreous Humor. Transp Porous Media. 2024 Feb; 151(3):533-558.. View in PubMed
  • Prediction of cognitive outcome after mild traumatic brain injury from acute measures of communication within brain networks. Cortex. 2024 02; 171:397-412.. View in PubMed
  • ENIGMA’s simple seven: Recommendations to enhance the reproducibility of resting-state fMRI in traumatic brain injury. Neuroimage Clin. 2024; 42:103585.. View in PubMed
  • Using Neuroimaging to Study Cerebral Amyloid Angiopathy and Its Relationship to Alzheimer’s Disease. J Alzheimers Dis. 2024; 97(4):1479-1502.. View in PubMed
  • Multimodal Analysis of Secondary Cerebellar Alterations After Pediatric Traumatic Brain Injury. JAMA Netw Open. 2023 11 01; 6(11):e2343410.. View in PubMed
  • Significant Acceleration of Regional Brain Aging and Atrophy After Mild Traumatic Brain Injury. J Gerontol A Biol Sci Med Sci. 2023 08 02; 78(8):1328-1338.. View in PubMed
  • Life After Mild Traumatic Brain Injury: Widespread Structural Brain Changes Associated With Psychological Distress Revealed With Multimodal Magnetic Resonance Imaging. Biol Psychiatry Glob Open Sci. 2023 Jul; 3(3):374-385.. View in PubMed
  • Regional Neuroanatomic Effects on Brain Age Inferred Using Magnetic Resonance Imaging and Ridge Regression. J Gerontol A Biol Sci Med Sci. 2023 06 01; 78(6):872-881.. View in PubMed
  • 3D Printing and processing of miniaturized transducers with near-pristine piezoelectric ceramics for localized cavitation. Nat Commun. 2023 Apr 27; 14(1):2418.. View in PubMed
  • Bridging Big Data: Procedures for Combining Non-equivalent Cognitive Measures from the ENIGMA Consortium. bioRxiv. 2023 Apr 07.. View in PubMed
  • Altered lateralization of the cingulum in deployment-related traumatic brain injury: An ENIGMA military-relevant brain injury study. Hum Brain Mapp. 2023 04 01; 44(5):1888-1900.. View in PubMed
  • Brain volume, energy balance, and cardiovascular health in two nonindustrial South American populations. Proc Natl Acad Sci U S A. 2023 03 28; 120(13):e2205448120.. View in PubMed
  • Challenges and opportunities for harmonization of cross-cultural neuropsychological data. Neuropsychology. 2023 Mar; 37(3):237-246.. View in PubMed
  • Anatomically interpretable deep learning of brain age captures domain-specific cognitive impairment. Proc Natl Acad Sci U S A. 2023 01 10; 120(2):e2214634120.. View in PubMed
  • Structural-functional connectivity bandwidth predicts processing speed in mild traumatic brain Injury: A multiplex network analysis. Neuroimage Clin. 2023; 38:103428.. View in PubMed
  • Exploring personalized structural connectomics for moderate to severe traumatic brain injury. Netw Neurosci. 2023; 7(1):160-183.. View in PubMed
  • Testosterone is positively associated with coronary artery calcium in a low cardiovascular disease risk population. Evol Med Public Health. 2023; 11(1):472-484.. View in PubMed
  • Prevalence of dementia and mild cognitive impairment in indigenous Bolivian forager-horticulturalists. Alzheimers Dement. 2023 01; 19(1):44-55.. View in PubMed
  • White matter degradation near cerebral microbleeds is associated with cognitive change after mild traumatic brain injury. Neurobiol Aging. 2022 12; 120:68-80.. View in PubMed
  • Brain age estimation reveals older adults’ accelerated senescence after traumatic brain injury. Geroscience. 2022 10; 44(5):2509-2525.. View in PubMed
  • Alzheimer’s disease after mild traumatic brain injury. Aging (Albany NY). 2022 07 12; 14(13):5292-5293.. View in PubMed
  • Age-dependent white matter disruptions after military traumatic brain injury: Multivariate analysis results from ENIGMA brain injury. Hum Brain Mapp. 2022 06 01; 43(8):2653-2667.. View in PubMed
  • Neuroanatomic Markers of Posttraumatic Epilepsy Based on MR Imaging and Machine Learning. AJNR Am J Neuroradiol. 2022 03; 43(3):347-353.. View in PubMed
  • Older age, male sex, and cerebral microbleeds predict white matter loss after traumatic brain injury. Geroscience. 2022 02; 44(1):83-102.. View in PubMed
  • Functional Connectome Dynamics After Mild Traumatic Brain Injury According to Age and Sex. Front Aging Neurosci. 2022; 14:852990.. View in PubMed
  • Mild Traumatic Brain Injury Results in Significant and Lasting Cortical Demyelination. Front Neurol. 2022; 13:854396.. View in PubMed
  • Vascular Cognitive Impairment After Mild Stroke: Connectomic Insights, Neuroimaging, and Knowledge Translation. Front Neurosci. 2022; 16:905979.. View in PubMed
  • Tractography methods and findings in brain tumors and traumatic brain injury. Neuroimage. 2021 12 15; 245:118651.. View in PubMed
  • The Indigenous South American Tsimane Exhibit Relatively Modest Decrease in Brain Volume With Age Despite High Systemic Inflammation. J Gerontol A Biol Sci Med Sci. 2021 11 15; 76(12):2147-2155.. View in PubMed
  • Acute cognitive impairment after traumatic brain injury predicts the occurrence of brain atrophy patterns similar to those observed in Alzheimer’s disease. Geroscience. 2021 08; 43(4):2015-2039.. View in PubMed
  • White Matter Disruption in Pediatric Traumatic Brain Injury: Results From ENIGMA Pediatric Moderate to Severe Traumatic Brain Injury. Neurology. 2021 Jul 19; 97(3):e298-e309.. View in PubMed
  • Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group. Brain Imaging Behav. 2021 Apr; 15(2):526-554.. View in PubMed
  • Cross-Sectional Volumes and Trajectories of the Human Brain, Gray Matter, White Matter and Cerebrospinal Fluid in 9473 Typically Aging Adults. Neuroinformatics. 2021 04; 19(2):347-366.. View in PubMed
  • The ENIGMA sports injury working group:- an international collaboration to further our understanding of sport-related brain injury. Brain Imaging Behav. 2021 Apr; 15(2):576-584.. View in PubMed
  • Coordinating Global Multi-Site Studies of Military-Relevant Traumatic Brain Injury: Opportunities, Challenges, and Harmonization Guidelines. Brain Imaging Behav. 2021 Apr; 15(2):585-613.. View in PubMed
  • A global collaboration to study intimate partner violence-related head trauma: The ENIGMA consortium IPV working group. Brain Imaging Behav. 2021 Apr; 15(2):475-503.. View in PubMed
  • Mapping the rest of the human connectome: Atlasing the spinal cord and peripheral nervous system. Neuroimage. 2021 01 15; 225:117478.. View in PubMed
  • Reduced Hippocampal GABA+ Is Associated With Poorer Episodic Memory in Healthy Older Women: A Pilot Study. Front Behav Neurosci. 2021; 15:695416.. View in PubMed
  • Acute cognitive deficits after traumatic brain injury predict Alzheimer’s disease-like degradation of the human default mode network. Geroscience. 2020 10; 42(5):1411-1429.. View in PubMed
  • Multimodal Imaging of Cerebral Microhemorrhages and White Matter Degradation in Geriatric Patients with Mild Traumatic Brain Injury. Methods Mol Biol. 2020; 2144:223-236.. View in PubMed
  • Neuroimaging and Psychometric Assessment of Mild Cognitive Impairment After Traumatic Brain Injury. Front Psychol. 2020; 11:1423.. View in PubMed
  • Neuroimaging of traumatic brain injury in military personnel: An overview. J Clin Neurosci. 2019 Dec; 70:1-10.. View in PubMed
  • Post-Traumatic Cerebral Microhemorrhages and their Effects Upon White Matter Connectivity in the Aging Human Brain. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:198-203.. View in PubMed
  • Correction to: Mechanisms underlying the EEG biomarker in Dup15q syndrome. Mol Autism. 2019; 10:37.. View in PubMed
  • The LONI QC System: A Semi-Automated, Web-Based and Freely-Available Environment for the Comprehensive Quality Control of Neuroimaging Data. Front Neuroinform. 2019; 13:60.. View in PubMed
  • Mechanisms underlying the EEG biomarker in Dup15q syndrome. Mol Autism. 2019; 10:29.. View in PubMed
  • Brain Segmentation From Computed Tomography of Healthy Aging and Geriatric Concussion at Variable Spatial Resolutions. Front Neuroinform. 2019; 13:9.. View in PubMed
  • Neuroinformatics and Analysis of Connectomic Alterations Due to Cerebral Microhemorrhages in Geriatric Mild Neurotrauma. ACM BCB. 2018 Aug-Sep; 2018:165-171.. View in PubMed
  • Cerebral microhemorrhages due to traumatic brain injury and their effects on the aging human brain. Neurobiol Aging. 2018 06; 66:158-164.. View in PubMed
  • Mild cognitive impairment and structural brain abnormalities in a sexagenarian with a history of childhood traumatic brain injury. J Neurosci Res. 2018 04; 96(4):652-660.. View in PubMed
  • Support Vector Machines, Multidimensional Scaling and Magnetic Resonance Imaging Reveal Structural Brain Abnormalities Associated With the Interaction Between Autism Spectrum Disorder and Sex. Front Comput Neurosci. 2018; 12:93.. View in PubMed
  • Macroscale White Matter Alterations Due to Traumatic Cerebral Microhemorrhages Are Revealed by Diffusion Tensor Imaging. Front Neurol. 2018; 9:948.. View in PubMed
  • Corrigendum: Resting-State Functional Connectivity in Autism Spectrum Disorders: A Review. Front Psychiatry. 2018; 9:268.. View in PubMed
  • Mobile Monitoring of Traumatic Brain Injury in Older Adults: Challenges and Opportunities. Neuroinformatics. 2017 07; 15(3):227-230.. View in PubMed
  • The connectomes of males and females with autism spectrum disorder have significantly different white matter connectivity densities. Sci Rep. 2017 04 11; 7:46401.. View in PubMed
  • Toward Precision and Reproducibility of Diffusion Tensor Imaging: A Multicenter Diffusion Phantom and Traveling Volunteer Study. AJNR Am J Neuroradiol. 2017 Mar; 38(3):537-545.. View in PubMed
  • Clinical neuroimaging in the preterm infant: Diagnosis and prognosis. Neuroimage Clin. 2017; 16:355-368.. View in PubMed
  • Traumatic Brain Injury Severity, Neuropathophysiology, and Clinical Outcome: Insights from Multimodal Neuroimaging. Front Neurol. 2017; 8:530.. View in PubMed
  • Multimodal Imaging of Neurometabolic Pathology due to Traumatic Brain Injury. Trends Neurosci. 2017 01; 40(1):39-59.. View in PubMed
  • Modeling 4D Pathological Changes by Leveraging Normative Models. Comput Vis Image Underst. 2016 10; 151:3-13.. View in PubMed
  • Scale-Dependent Variability and Quantitative Regimes in Graph-Theoretic Representations of Human Cortical Networks. Brain Connect. 2016 Mar; 6(2):152-63.. View in PubMed
  • Resting-State Functional Connectivity in Autism Spectrum Disorders: A Review. Front Psychiatry. 2016; 7:205.. View in PubMed
  • Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood. Brain Imaging Behav. 2015 Dec; 9(4):678-89.. View in PubMed
  • Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterol Motil. 2015 Aug; 27(8):1075-81.. View in PubMed
  • Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 Aug; 156(8):1545-1554.. View in PubMed
  • Epileptogenic focus localization in treatment-resistant post-traumatic epilepsy. J Clin Neurosci. 2015 Apr; 22(4):627-31.. View in PubMed
  • The DTI connectivity of the human claustrum. Hum Brain Mapp. 2015 Mar; 36(3):827-38.. View in PubMed
  • Trajectory of frequency stability in typical development. Brain Imaging Behav. 2015 Mar; 9(1):5-18.. View in PubMed
  • Functional neuroimaging of traumatic brain injury: advances and clinical utility. Neuropsychiatr Dis Treat. 2015; 11:2355-65.. View in PubMed
  • Longitudinal quantification and visualization of intracerebral haemorrhage using multimodal magnetic resonance and diffusion tensor imaging. Brain Inj. 2015; 29(4):438-45.. View in PubMed
  • Variability of magnetoencephalographic sensor sensitivity measures as a function of age, brain volume and cortical area. Clin Neurophysiol. 2014 Oct; 125(10):1973-84.. View in PubMed
  • Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury. J Neurosurg Sci. 2014 Sep; 58(3):129-44.. View in PubMed
  • 4D ACTIVE CUT: AN INTERACTIVE TOOL FOR PATHOLOGICAL ANATOMY MODELING. Proc IEEE Int Symp Biomed Imaging. 2014 Apr; 2014:529-532.. View in PubMed
  • Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury. Front Neuroinform. 2014; 8:19.. View in PubMed
  • Systematic network lesioning reveals the core white matter scaffold of the human brain. Front Hum Neurosci. 2014; 8:51.. View in PubMed
  • ANALYZING IMAGING BIOMARKERS FOR TRAUMATIC BRAIN INJURY USING 4D MODELING OF LONGITUDINAL MRI. Proc IEEE Int Symp Biomed Imaging. 2013 Dec 31; 2013:1392-1395.. View in PubMed
  • Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury. Clin Neurophysiol. 2013 Nov; 124(11):2129-45.. View in PubMed
  • Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. Clin Neurol Neurosurg. 2013 Oct; 115(10):2159-65.. View in PubMed
  • Early metabolic crisis-related brain atrophy and cognition in traumatic brain injury. Brain Imaging Behav. 2013 Sep; 7(3):307-15.. View in PubMed
  • Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. IEEE Trans Biomed Eng. 2013 Sep; 60(9):2511-20.. View in PubMed
  • DTI tractography and white matter fiber tract characteristics in euthymic bipolar I patients and healthy control subjects. Brain Imaging Behav. 2013 Jun; 7(2):129-39.. View in PubMed
  • The structural, connectomic and network covariance of the human brain. Neuroimage. 2013 Feb 01; 66:489-99.. View in PubMed
  • Modeling 4D Changes in Pathological Anatomy using Domain Adaptation: Analysis of TBI Imaging using a Tumor Database. Multimodal Brain Image Anal (2013). 2013; 8159:31-39.. View in PubMed
  • Circular representation of human cortical networks for subject and population-level connectomic visualization. Neuroimage. 2012 Apr 02; 60(2):1340-51.. View in PubMed
  • A Patient-Specific Segmentation Framework for Longitudinal MR Images of Traumatic Brain Injury. Proc SPIE Int Soc Opt Eng. 2012 Mar 23; 8314:831402.. View in PubMed
  • Source cancellation profiles of electroencephalography and magnetoencephalography. Neuroimage. 2012 Feb 01; 59(3):2464-74.. View in PubMed
  • Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Neuroimage Clin. 2012; 1(1):1-17.. View in PubMed
  • Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury. Front Neurol. 2012; 3:10.. View in PubMed
  • Mapping connectivity damage in the case of Phineas Gage. PLoS One. 2012; 7(5):e37454.. View in PubMed
  • SEGMENTATION OF SERIAL MRI OF TBI PATIENTS USING PERSONALIZED ATLAS CONSTRUCTION AND TOPOLOGICAL CHANGE ESTIMATION. Proc IEEE Int Symp Biomed Imaging. 2012; 1152-1155.. View in PubMed
  • Theta oscillations are sensitive to both early and late conflict processing stages: effects of alcohol intoxication. PLoS One. 2012; 7(8):e43957.. View in PubMed
  • Comparison of acute and chronic traumatic brain injury using semi-automatic multimodal segmentation of MR volumes. J Neurotrauma. 2011 Nov; 28(11):2287-306.. View in PubMed
  • Sequential temporo-fronto-temporal activation during monitoring of the auditory environment for temporal patterns. Hum Brain Mapp. 2011 Aug; 32(8):1260-76.. View in PubMed
  • Geometric metamorphosis. Med Image Comput Comput Assist Interv. 2011; 14(Pt 2):639-46.. View in PubMed
  • Comparison of conventional filtering and independent component analysis for artifact reduction in simultaneous gastric EMG and magnetogastrography from porcines. IEEE Trans Biomed Eng. 2009 Nov; 56(11):2611-8.. View in PubMed
  • Biomagnetic signatures of uncoupled gastric musculature. Neurogastroenterol Motil. 2009 Jul; 21(7):778-e50.. View in PubMed
  • Partial independence of bioelectric and biomagnetic fields and its implications for encephalography and cardiography. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 May; 79(5 Pt 1):051908.. View in PubMed
  • Gastrointestinal arrhythmias are associated with statistically significant fluctuations in systemic information dimension. Physiol Meas. 2008 May; 29(5):N33-40.. View in PubMed
  • An integrative software package for gastrointestinal biomagnetic data acquisition and analysis using SQUID magnetometers. Comput Methods Programs Biomed. 2006 Aug; 83(2):83-94.. View in PubMed
  • Biomagnetic characterization of spatiotemporal parameters of the gastric slow wave. Neurogastroenterol Motil. 2006 Aug; 18(8):619-31.. View in PubMed
  • Magnetogastrographic detection of gastric electrical response activity in humans. Phys Med Biol. 2006 Mar 07; 51(5):1347-60.. View in PubMed
  • Artifact reduction in magnetogastrography using fast independent component analysis. Physiol Meas. 2005 Dec; 26(6):1059-73.. View in PubMed
  • Ellipsoidal electrogastrographic forward modelling. Phys Med Biol. 2005 Sep 21; 50(18):4429-44.. View in PubMed
  • Theoretical and computational multiple regression study of gastric electrical activity using dipole tracing from magnetic field measurements. J Biol Phys. 2004 Sep; 30(3):239-59.. View in PubMed
  • Theoretical and computational methods for the noninvasive detection of gastric electrical source coupling. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 May; 69(5 Pt 1):051920.. View in PubMed
  • Theoretical ellipsoidal model of gastric electrical control activity propagation. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Nov; 68(5 Pt 1):051905.. View in PubMed

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