Andrew Cheng

Dr. Andrew Cheng received his B.S. in electrical engineering and computer science from University of California, Berkeley and M.D. from University of Michigan. After medical school, he completed a residency in pediatrics at University of California, Los Angeles, and fellowships in pediatric cardiology and advanced cardiac imaging at Children’s Hospital Los Angeles. Dr. Cheng is currently an Associate Professor of Clinical Pediatrics at USC and an attending Pediatric Cardiologist at Children’s Hospital Los Angeles. His clinical interests include cardiac magnetic resonance imaging, cardiac computed tomography, and care of patients with the Fontan circulation. Dr. Cheng’s primary research utilizes cardiac magnetic resonance imaging and computational fluid dynamic simulations to study the role of blood viscosity in Fontan circulation pathophysiology. He is the director of CHLA’s multidisciplinary Fontan Clinic and CHLA’s site PI for the Fontan Outcomes Network.

• Children’s Hospital Los Angeles: Nominee, Morris and Mary Press Humanism Award, 2020
• University of Southern California: Provost’s Postdoctoral Scholar Research Grant, 2015-2016
• American Society of Echocardiography: Travel Grant, 2015
• American Academy of Pediatrics: Section on Cardiology and Cardiac Surgery Research Fellowship Award, 2014-2015
• Eta Kappa Nu (National Electrical Engineering Honor Society): Elected Member, 2001
• Tau Beta Pi (National Engineering Honor Society): Elected Member, 2001

• Finding our ROLE: How and why to reframe essentialist approaches to language. Cognition. 2026 Jun; 271:106444.. View in PubMed
• The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants. Circulation. 2026 Apr 21; 153(16):1182-1195.. View in PubMed
• Smoking Prevalence and Cessation in Skin Cancer Survivors. Dermatology. 2026; 242(3):280-283.. View in PubMed
• CMR Findings in the Long-Term Outcomes After Multisystem Inflammatory Syndrome in Children (MUSIC) Study. Circ Cardiovasc Imaging. 2025 Sep; 18(9):e017420.. View in PubMed
• Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial. Lancet. 2025 Aug 16; 406(10504):719-730.. View in PubMed
• Significance of Reynolds Number Consistency in Non-Newtonian Hemodynamic Simulations: Insights from Fontan Circulation. Phys Fluids (1994). 2025 Aug; 37(8).. View in PubMed
• Viral Etiologies of Acute Respiratory Illness in Older Adults and of Congestive Heart Failure and Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization During 2 Prepandemic Respiratory Seasons. Open Forum Infect Dis. 2025 Jul; 12(7):ofaf366.. View in PubMed
• Clinical and echocardiographic features of right ventricular dysfunction and biventricular dysfunction in children. Ann Pediatr Cardiol. 2025 Jul-Aug; 18(4):337-344.. View in PubMed
• Efruxifermin in Compensated Liver Cirrhosis Caused by MASH. N Engl J Med. 2025 Jun 26; 392(24):2413-2424.. View in PubMed
• Corrigendum to “Cardiac manifestations and outcomes of COVID-19 vaccine-associated myocarditis in the young in the USA: longitudinal results from the Myocarditis After COVID Vaccination (MACiV) multicenter study”. EClinicalMedicine. 2025 Jun; 84:103268.. View in PubMed
• Transcatheter Stenting to Restore Cross-Sectional Area of Extracardiac Fontan Conduits. Catheter Cardiovasc Interv. 2025 04; 105(5):1134-1141.. View in PubMed
• Nutrition delivery during hospitalisation after critical illness in Australia and New Zealand: a multicentre, prospective observational study. J Hum Nutr Diet. 2025 Feb; 38(1):e13385.. View in PubMed
• Skin cancer treatment environment and survivorship resources among sexual and gender minority patients: results of the OUT National Cancer Survey. Arch Dermatol Res. 2025 Jan 16; 317(1):253.. View in PubMed
• Safety and Efficacy of Efruxifermin in Combination With a GLP-1 Receptor Agonist in Patients With NASH/MASH and Type 2 Diabetes in a Randomized Phase 2 Study. Clin Gastroenterol Hepatol. 2025 Jan; 23(1):103-113.. View in PubMed
• Relative Contribution of Diagnostic Testing to the Diagnosis of Respiratory Syncytial Virus in Hospitalized Adults in the United States. J Infect Dis. 2024 Dec 16; 230(6):1342-1351.. View in PubMed
• The impact of blood viscosity modeling on computational fluid dynamic simulations of pediatric patients with Fontan circulation. Phys Fluids (1994). 2024 Nov; 36(11):111911.. View in PubMed
• Cardiac manifestations and outcomes of COVID-19 vaccine-associated myocarditis in the young in the USA: longitudinal results from the Myocarditis After COVID Vaccination (MACiV) multicenter study. EClinicalMedicine. 2024 Oct; 76:102809.. View in PubMed
• Analyzing RNA-Seq data from Chlamydia with super broad transcriptomic activation: challenges, solutions, and implications for other systems. BMC Genomics. 2024 Aug 25; 25(1):801.. View in PubMed
• Influenza Vaccine Effectiveness Pre-pandemic Among Adults Hospitalized With Congestive Heart Failure or Chronic Obstructive Pulmonary Disease and Older Adults. Clin Infect Dis. 2024 04 10; 78(4):1065-1072.. View in PubMed
• Decreased erythrocyte aggregation in Glenn and Fontan: univentricular circulation as a rheologic disease model. Pediatr Res. 2024 Apr; 95(5):1335-1345.. View in PubMed
• Nurse and Social Worker Palliative Telecare Team and Quality of Life in Patients With COPD, Heart Failure, or Interstitial Lung Disease: The ADAPT Randomized Clinical Trial. JAMA. 2024 01 16; 331(3):212-223.. View in PubMed
• Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance. mBio. 2024 01 16; 15(1):e0203623.. View in PubMed
• Cardiovascular Follow-up of Patients Treated for MIS-C. Pediatrics. 2023 12 01; 152(6).. View in PubMed
• Atopic Dermatitis and Bullying Among US Adolescents. JAMA Dermatol. 2023 12 01; 159(12):1395-1397.. View in PubMed
• Safety and efficacy of once-weekly efruxifermin versus placebo in non-alcoholic steatohepatitis (HARMONY): a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial. Lancet Gastroenterol Hepatol. 2023 12; 8(12):1080-1093.. View in PubMed
• Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance. bioRxiv. 2023 Aug 02.. View in PubMed
• Screening left ventricular systolic dysfunction in children using intrinsic frequencies of carotid pressure waveforms measured by a novel smartphone-based device. Physiol Meas. 2023 03 01; 44(3).. View in PubMed
• Benchmarking cell-type clustering methods for spatially resolved transcriptomics data. Brief Bioinform. 2023 01 19; 24(1).. View in PubMed
• Examination of Adverse Reactions After COVID-19 Vaccination Among Patients With a History of Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2023 01 03; 6(1):e2248987.. View in PubMed
• A randomized, double-blind, placebo-controlled phase IIa trial of efruxifermin for patients with compensated NASH cirrhosis. JHEP Rep. 2023 Jan; 5(1):100563.. View in PubMed
• Myocardial Iron Overload Causes Subclinical Myocardial Dysfunction in Sickle Cell Disease. JACC Cardiovasc Imaging. 2022 08; 15(8):1510-1512.. View in PubMed
• Effects of brain tissue oxygen (PbtO2) guided management on patient outcomes following severe traumatic brain injury: A systematic review and meta-analysis. J Clin Neurosci. 2022 May; 99:349-358.. View in PubMed
• The NHLBI Study on Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC): Design and Objectives. Am Heart J. 2022 01; 243:43-53.. View in PubMed
• An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. iScience. 2021 Nov 19; 24(11):103221.. View in PubMed
• Progression in Fontan conduit stenosis and hemodynamic impact during childhood and adolescence. J Thorac Cardiovasc Surg. 2021 Aug; 162(2):372-380.e2.. View in PubMed
• Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial. Nat Med. 2021 07; 27(7):1262-1271.. View in PubMed
• Biventricular Repair in Interrupted Aortic Arch and Ventricular Septal Defect With a Small Left Ventricular Outflow Tract. Ann Thorac Surg. 2021 02; 111(2):637-644.. View in PubMed
• Assessing non-Mendelian inheritance in inherited axonopathies. Genet Med. 2020 12; 22(12):2114-2119.. View in PubMed
• Fully‑automated deep‑learning segmentation of pediatric cardiovascular magnetic resonance of patients with complex congenital heart diseases. J Cardiovasc Magn Reson. 2020 11 30; 22(1):80.. View in PubMed
• Duration of Cellular and Humoral Responses after Quadrivalent Human Papillomavirus Vaccination in Healthy Female Adults with or without Prior Type 16 and/or 18 Exposure. Vaccines (Basel). 2020 Jun 30; 8(3).. View in PubMed
• Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients. Cell Rep Med. 2020 06 23; 1(3):100040.. View in PubMed
• Proof-of-concept for a non-invasive, portable, and wireless device for cardiovascular monitoring in pediatric patients. PLoS One. 2020; 15(1):e0227145.. View in PubMed
• A 4D flow MRI evaluation of the impact of shear-dependent fluid viscosity on in vitro Fontan circulation flow. Am J Physiol Heart Circ Physiol. 2019 12 01; 317(6):H1243-H1253.. View in PubMed
• Artificial intelligence in pediatric and adult congenital cardiac MRI: an unmet clinical need. Cardiovasc Diagn Ther. 2019 Oct; 9(Suppl 2):S310-S325.. View in PubMed
• Methamphetamine-Induced Tachydysrhythmia in an Adolescent in Diabetic Ketoacidosis. J Emerg Med. 2019 Jun; 56(6):e111-e114.. View in PubMed
• Differences in Right Ventricular Physiologic Response to Chronic Volume Load in Patients with Repaired Pulmonary Atresia Intact Ventricular Septum/Critical Pulmonary Stenosis Versus Tetralogy of Fallot. Pediatr Cardiol. 2019 Mar; 40(3):526-536.. View in PubMed
• Safety of elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide in HIV-1-infected adults with end-stage renal disease on chronic haemodialysis: an open-label, single-arm, multicentre, phase 3b trial. Lancet HIV. 2018 Dec 13.. View in PubMed
• Switching to fixed-dose bictegravir, emtricitabine, and tenofovir alafenamide from dolutegravir plus abacavir and lamivudine in virologically suppressed adults with HIV-1: 48 week results of a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial. Lancet HIV. 2018 07; 5(7):e357-e365.. View in PubMed
• Efficacy and safety of switching to fixed-dose bictegravir, emtricitabine, and tenofovir alafenamide from boosted protease inhibitor-based regimens in virologically suppressed adults with HIV-1: 48 week results of a randomised, open-label, multicentre, phase 3, non-inferiority trial. Lancet HIV. 2018 07; 5(7):e347-e356.. View in PubMed
• Brief Report: Efficacy and Safety of Switching to Coformulated Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide (E/C/F/TAF) in Virologically Suppressed Women. J Acquir Immune Defic Syndr. 2018 06 01; 78(2):209-213.. View in PubMed
• Tenofovir alafenamide plus emtricitabine versus abacavir plus lamivudine for treatment of virologically suppressed HIV-1-infected adults: a randomised, double-blind, active-controlled, non-inferiority phase 3 trial. Lancet HIV. 2018 04; 5(4):e162-e171.. View in PubMed
• Experimental Investigation of the Effect of Non-Newtonian Behavior of Blood Flow in the Fontan Circulation. Eur J Mech B Fluids. 2018 Mar-Apr; 68:184-192.. View in PubMed
• Bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection (GS-US-380-1489): a double-blind, multicentre, phase 3, randomised controlled non-inferiority trial. Lancet. 2017 Nov 04; 390(10107):2063-2072.. View in PubMed
• Coformulated bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir with emtricitabine and tenofovir alafenamide, for initial treatment of HIV-1 infection (GS-US-380-1490): a randomised, double-blind, multicentre, phase 3, non-inferiority trial. Lancet. 2017 Nov 04; 390(10107):2073-2082.. View in PubMed
• 6q25.1 (TAB2) microdeletion syndrome: Congenital heart defects and cardiomyopathy. Am J Med Genet A. 2017 Jul; 173(7):1848-1857.. View in PubMed
• Brief Report: Long-Term (96-Week) Efficacy and Safety After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in HIV-Infected, Virologically Suppressed Adults. J Acquir Immune Defic Syndr. 2017 06 01; 75(2):226-231.. View in PubMed
• Brief Report: Randomized, Double-Blind Comparison of Tenofovir Alafenamide (TAF) vs Tenofovir Disoproxil Fumarate (TDF), Each Coformulated With Elvitegravir, Cobicistat, and Emtricitabine (E/C/F) for Initial HIV-1 Treatment: Week 144 Results. J Acquir Immune Defic Syndr. 2017 06 01; 75(2):211-218.. View in PubMed
• Antiviral Activity, Safety, and Pharmacokinetics of Bictegravir as 10-Day Monotherapy in HIV-1-Infected Adults. J Acquir Immune Defic Syndr. 2017 05 01; 75(1):61-66.. View in PubMed
• Efficacy and safety of emtricitabine/tenofovir alafenamide (FTC/TAF) vs. emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) as a backbone for treatment of HIV-1 infection in virologically suppressed adults: subgroup analysis by third agent of a randomized, double-blind, active-controlled phase 3 trial. HIV Clin Trials. 2017 05; 18(3):135-140.. View in PubMed
• Switching from tenofovir disoproxil fumarate to tenofovir alafenamide coformulated with rilpivirine and emtricitabine in virally suppressed adults with HIV-1 infection: a randomised, double-blind, multicentre, phase 3b, non-inferiority study. Lancet HIV. 2017 05; 4(5):e195-e204.. View in PubMed
• Switching from efavirenz, emtricitabine, and tenofovir disoproxil fumarate to tenofovir alafenamide coformulated with rilpivirine and emtricitabine in virally suppressed adults with HIV-1 infection: a randomised, double-blind, multicentre, phase 3b, non-inferiority study. Lancet HIV. 2017 05; 4(5):e205-e213.. View in PubMed
• Bictegravir versus dolutegravir, each with emtricitabine and tenofovir alafenamide, for initial treatment of HIV-1 infection: a randomised, double-blind, phase 2 trial. Lancet HIV. 2017 04; 4(4):e154-e160.. View in PubMed
• A Randomized, Open-Label Trial to Evaluate Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Plus Darunavir in Treatment-Experienced HIV-1-Infected Adults. J Acquir Immune Defic Syndr. 2017 Feb 01; 74(2):193-200.. View in PubMed
• Brief Report: Switching to Tenofovir Alafenamide, Coformulated With Elvitegravir, Cobicistat, and Emtricitabine, in HIV-Infected Adults With Renal Impairment: 96-Week Results From a Single-Arm, Multicenter, Open-Label Phase 3 Study. J Acquir Immune Defic Syndr. 2017 Feb 01; 74(2):180-184.. View in PubMed
• Skeletal muscle power and fatigue at the tolerable limit of ramp-incremental exercise in COPD. J Appl Physiol (1985). 2016 12 01; 121(6):1365-1373.. View in PubMed
• Equivalent Decline in Inflammation Markers with Tenofovir Disoproxil Fumarate vs. Tenofovir Alafenamide. EBioMedicine. 2016 Nov; 13:321-327.. View in PubMed
• Integrase inhibitor versus protease inhibitor based regimen for HIV-1 infected women (WAVES): a randomised, controlled, double-blind, phase 3 study. Lancet HIV. 2016 09; 3(9):e410-e420.. View in PubMed
• Left bronchial compression and pulmonary hypertension related to anomalous right pulmonary artery. Cardiol Young. 2016 Jun; 26(5):999-1001.. View in PubMed
• Prenatal diagnosis of tetralogy of Fallot with a double aortic arch. Cardiol Young. 2016 Jun; 26(5):973-5.. View in PubMed
• Brief Report: A Randomized, Double-Blind Comparison of Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate, Each Coformulated With Elvitegravir, Cobicistat, and Emtricitabine for Initial HIV-1 Treatment: Week 96 Results. J Acquir Immune Defic Syndr. 2016 May 01; 72(1):58-64.. View in PubMed
• Switching to Tenofovir Alafenamide, Coformulated With Elvitegravir, Cobicistat, and Emtricitabine, in HIV-Infected Patients With Renal Impairment: 48-Week Results From a Single-Arm, Multicenter, Open-Label Phase 3 Study. J Acquir Immune Defic Syndr. 2016 Apr 15; 71(5):530-7.. View in PubMed
• Elevated Low-Shear Blood Viscosity is Associated with Decreased Pulmonary Blood Flow in Children with Univentricular Heart Defects. Pediatr Cardiol. 2016 Apr; 37(4):789-801.. View in PubMed
• Validation of a classification system for causes of death in critical care: an assessment of inter-rater reliability. Crit Care Resusc. 2016 Mar; 18(1):50-4.. View in PubMed
• Integrative epigenetic profiling analysis identifies DNA methylation changes associated with chronic alcohol consumption. Comput Biol Med. 2015 Sep; 64:299-306.. View in PubMed
• Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear. J Proteomics. 2014 May 30; 103:178-93.. View in PubMed
• Pediatric Cardiology, Cardiac Surgery, and Intensive Care (Ed. Eduardo M. da Cruz, Dunbar Ivy, and James Jaggers). “Biodegradable Implants”. 2014.
• A randomized double-blind comparison of coformulated elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate versus efavirenz/emtricitabine/tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: analysis of week 96 results. J Acquir Immune Defic Syndr. 2013 May 01; 63(1):96-100.. View in PubMed
• Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet. 2012 Jun 30; 379(9835):2429-2438.. View in PubMed
• The impact of a screensaver in promoting hand hygiene. Am J Infect Control. 2009 Dec; 37(10):867-8.. View in PubMed
• Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV. N Engl J Med. 2006 Jan 19; 354(3):251-60.. View in PubMed
• Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial. JAMA. 2004 Jul 14; 292(2):191-201.. View in PubMed

• Wood, John
• Starnes, Vaughn
• Kloner, Robert
• Detterich, Jon
• Berman, Darren
• Klausner, Jeffrey