Arnold Sipos, MD, PhD

Research Assistant Professor of Pathology (Part-Time)

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Overview

Dr. Sipos earned his medical degree from Semmelweis University School of Medicine. He then completed his PhD in Pathophysiology. Prior to joining the Division of Pulmonary, Critical Care and Sleep Medicine as an Assistant Professor, Dr. Sipos served as a Postdoctoral Research Associate for the Department of Medicine.

Awards

  • Semmelweis University: Scientific Award for Medical Students, 2001
  • Semmelweis University: Scientific Award for Medical Students, 2002
  • Hungary: National Scientific Award for Medical Students, 2003
  • Semmelweis University Research Council: Research Grant, 2003
  • Semmelweis University: Scientific Award for Medical Students, 2003
  • European Physiological Societies: Travel Grant, 2003
  • Semmelweis University Research Council: Scientific Merit, 2004
  • Experimental Biology Travel Grant, 2007
  • American Heart Association: Postdoctoral Fellowship, 2007
     – 2009
  • Amgen: Postdoctoral Excellence in Renal Research Award, 2008

Publications

  • Increased lung cell susceptibility to injury due to autophagic overload after exposure to nanoparticles. Am J Physiol Lung Cell Mol Physiol. 2026 Aug 01; 331(2):L197-L205.. View in PubMed
  • In-house Fabrication of Nanoplastics of Tunable Composition and Application: Assessment of Bioelectric Changes in Primary Rat Lung Alveolar Epithelial Cell Monolayers Exposed to Nanoplastics. Bio Protoc. 2025 Jun 05; 15(11):e5329.. View in PubMed
  • Real-Time Autophagic Flux Measurements in Live Cells Using a Novel Fluorescent Marker DAPRed. Bio Protoc. 2024 Mar 05; 14(5):e4949.. View in PubMed
  • Kinetics of autophagic activity in nanoparticle-exposed lung adenocarcinoma (A549) cells. Autophagy Rep. 2023; 2(1).. View in PubMed
  • Biokinetic modeling of nanoparticle interactions with lung alveolar epithelial cells: uptake, intracellular processing, and egress. Am J Physiol Regul Integr Comp Physiol. 2021 01 01; 320(1):R36-R43.. View in PubMed
  • Evidence for Nanoparticle-Induced Lysosomal Dysfunction in Lung Adenocarcinoma (A549) Cells. Int J Mol Sci. 2019 Oct 23; 20(21).. View in PubMed
  • Alveolar epithelial cell processing of nanoparticles activates autophagy and lysosomal exocytosis. Am J Physiol Lung Cell Mol Physiol. 2018 08 01; 315(2):L286-L300.. View in PubMed
  • The macula densa prorenin receptor is essential in renin release and blood pressure control. Am J Physiol Renal Physiol. 2018 09 01; 315(3):F521-F534.. View in PubMed
  • Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis. Am J Respir Cell Mol Biol. 2014 Aug; 51(2):210-22.. View in PubMed
  • Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms. Nanomedicine. 2013 Aug; 9(6):786-94.. View in PubMed