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Arun Durvasula, PhD

Assistant Professor of Population and Public Health Sciences and Quantitative and Computational Biology

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Email durvasul@usc.edu
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Awards

  • National Institute of Health: Outstanding Investigator Award, 2025-2030
  • ASHG Charles J. Epstein Trainee Award for Excellence in Human Genetics Research Semi-finalist, 2023
  • Dimitris N. Chorafas Foundation Award, 2021
  • National Science Foundation Graduate Student Fellowship, 2018-2021

Publications

  • Exposure accumulation drives age-dependent disease architectures and polygenic risk scores. medRxiv. 2025 Nov 07.. View in PubMed
  • Pathway-specific polygenic scores substantially increase the discovery of gene-adiposity interactions impacting liver biomarkers. HGG Adv. 2025 Sep 11; 7(1):100515.. View in PubMed
  • Addressing missing context in regulatory variation across primate evolution. Curr Opin Genet Dev. 2025 Aug; 93:102374.. View in PubMed
  • Identifying independent causal cell types for human diseases and risk variants. medRxiv. 2025 Jul 03.. View in PubMed
  • Pathway-specific polygenic scores substantially increase the discovery of gene-adiposity interactions impacting liver biomarkers. medRxiv. 2025 May 21.. View in PubMed
  • Addressing missing context in regulatory variation across primate evolution. ArXiv. 2025 Apr 02.. View in PubMed
  • Distinct explanations underlie gene-environment interactions in the UK Biobank. Am J Hum Genet. 2025 Mar 06; 112(3):644-658.. View in PubMed
  • Insufficient Evidence for a Severe Bottleneck in Humans During the Early to Middle Pleistocene Transition. Mol Biol Evol. 2025 Feb 03; 42(2).. View in PubMed
  • Distinct explanations underlie gene-environment interactions in the UK Biobank. medRxiv. 2024 Apr 18.. View in PubMed
  • Accurate inference of population history in the presence of background selection. bioRxiv. 2024 Jan 20.. View in PubMed
  • Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection. Res Sq. 2023 Dec 15.. View in PubMed
  • Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection. medRxiv. 2023 Dec 04.. View in PubMed
  • Age-dependent topic modeling of comorbidities in UK Biobank identifies disease subtypes with differential genetic risk. Nat Genet. 2023 11; 55(11):1854-1865.. View in PubMed
  • The Impact of Genomic Variation on Function (IGVF) Consortium. ArXiv. 2023 Jul 24.. View in PubMed
  • The lingering effects of Neanderthal introgression on human complex traits. Elife. 2023 03 20; 12.. View in PubMed
  • MaLAdapt Reveals Novel Targets of Adaptive Introgression From Neanderthals and Denisovans in Worldwide Human Populations. Mol Biol Evol. 2023 01 04; 40(1).. View in PubMed
  • Advancing admixture graph estimation via maximum likelihood network orientation. Bioinformatics. 2021 07 12; 37(Suppl_1):i142-i150.. View in PubMed
  • Negative selection on complex traits limits phenotype prediction accuracy between populations. Am J Hum Genet. 2021 04 01; 108(4):620-631.. View in PubMed
  • Ancient balancing selection maintains incompatible versions of the galactose pathway in yeast. Science. 2021 01 22; 371(6527):415-419.. View in PubMed
  • A community-maintained standard library of population genetic models. Elife. 2020 06 23; 9.. View in PubMed
  • Recovering signals of ghost archaic introgression in African populations. Sci Adv. 2020 02; 6(7):eaax5097.. View in PubMed
  • A statistical model for reference-free inference of archaic local ancestry. PLoS Genet. 2019 05; 15(5):e1008175.. View in PubMed
  • Gene expression drives the evolution of dominance. Nat Commun. 2018 07 16; 9(1):2750.. View in PubMed
  • Natural selection interacts with recombination to shape the evolution of hybrid genomes. Science. 2018 May 11; 360(6389):656-660.. View in PubMed
  • Natural Selection and Origin of a Melanistic Allele in North American Gray Wolves. Mol Biol Evol. 2018 05 01; 35(5):1190-1209.. View in PubMed
  • African genomes illuminate the early history and transition to selfing in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2017 05 16; 114(20):5213-5218.. View in PubMed
  • angsd-wrapper: utilities for analysing next-generation sequencing data. Mol Ecol Resour. 2016 Nov; 16(6):1449-1454.. View in PubMed
  • Recent demography drives changes in linked selection across the maize genome. Nat Plants. 2016 06 13; 2:16084.. View in PubMed

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