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Ba xuan Hoang, MD, PhD

Assistant Professor of Research Surgery

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Email baxuanho@usc.edu
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Publications

  • Synergistic anti-tumor effect of fenbendazole and diisopropylamine dichloroacetate in immunodeficient BALB/c nude mice transplanted with A549 lung cancer cells. Transl Lung Cancer Res. 2025 Jul 31; 14(7):2509-2521.. View in PubMed
  • Immunosuppressive Tumor Microenvironment of Osteosarcoma. Cancers (Basel). 2025 Jun 24; 17(13).. View in PubMed
  • ECM Stiffness-Induced Redox Signaling Enhances Stearoyl Gemcitabine Efficacy in Pancreatic Cancer. Cancers (Basel). 2025 Mar 03; 17(5).. View in PubMed
  • Distinct outcomes from targeted perturbations of the multi-subunit SCFSkp2 E3 ubiquitin ligase in blocking Trp53/Rb1-null prostate tumorigenesis. Commun Biol. 2025 Feb 22; 8(1):278.. View in PubMed
  • Viscoelastic Hydrogel Modulates Phenotype of Macrophage-Derived Multinucleated Cells and Macrophage Differentiation in Foreign Body Reactions. J Biomed Mater Res A. 2025 01; 113(1):e37814.. View in PubMed
  • Efficacy and Safety of Vuong Hoat Natural Health Supplement in Managing Low Back Pain: A Randomized Clinical Trial. J Med Food. 2025 Jan; 28(1):87-95.. View in PubMed
  • A Surgical Technique Guide for Percutaneous Screw Fixation for Metastatic Pelvic Lesions. JBJS Essent Surg Tech. 2025 Jan-Mar; 15(1).. View in PubMed
  • Investigation of Effectiveness of Nowarta110 Against Murine Malignant Melanoma in an Implanted Animal Model. Anticancer Res. 2024 Dec; 44(12):5219-5224.. View in PubMed
  • Fenbendazole and Diisopropylamine Dichloroacetate Exert Synergistic Anti-cancer Effects by Inducing Apoptosis and Arresting the Cell Cycle in A549 Lung Cancer Cells. Anticancer Res. 2024 Nov; 44(11):4761-4772.. View in PubMed
  • Investigation of the Efficacy of Nowarta110 in the Treatment of HPV-16 and HPV-18 Oncogenically-transformed Human Cells and Cancer-implanted Animal Models. Anticancer Res. 2024 11; 44(11):4723-4728.. View in PubMed
  • scDAPP: a comprehensive single-cell transcriptomics analysis pipeline optimized for cross-group comparison. NAR Genom Bioinform. 2024 Sep; 6(4):lqae134.. View in PubMed
  • Oral Fenbendazole for Cancer Therapy in Humans and Animals. Anticancer Res. 2024 Sep; 44(9):3725-3735.. View in PubMed
  • Area Socioeconomic Status is Associated with Refusal of Recommended Surgery in Patients with Metastatic Bone and Joint Disease. Ann Surg Oncol. 2024 Aug; 31(8):4882-4893.. View in PubMed
  • Comprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional target pathways. bioRxiv. 2024 Jun 06.. View in PubMed
  • scDAPP: a comprehensive single-cell transcriptomics analysis pipeline optimized for cross-group comparison. bioRxiv. 2024 May 09.. View in PubMed
  • Association of Socioeconomic Status With Worse Overall Survival in Patients With Bone and Joint Cancer. J Am Acad Orthop Surg. 2024 Apr 01; 32(7):e346-e355.. View in PubMed
  • Effectiveness of Bach Nien Kien Health Supplement in the Treatment of Patients With Symptomatic Knee Osteoarthritis. In Vivo. 2024 Mar-Apr; 38(2):963-970.. View in PubMed
  • Pancreatic cancer-derived organoids alter muscle fiber type and increased energy consumption leading to cachexia. Cancer Res (2024) 84 (6_Supplement): 382.
  • Enhanced efficacy of gemcitabine analogs and AZD 1775 combination therapy in patient-derived organoids. Cancer Epidemiology Biomarkers & Prevention. 2024; 33(9).
  • Zinc Iodide Dimethyl Sulfoxide Reduces Collagen Deposition by Increased Matrix Metalloproteinase-2 Expression and Activity in Lung Fibroblasts. Biomedicines. 2024; 12(june 12):1257.
  • Impact of gemcitabine modification on redox-driven responses in pancreatic cancer organoids cultured in distinct 3D microenvironments. Cancer Res (2024) 84 (6_Supplement): 3167.
  • Engineering tissue models to elucidate prostate cancer bone metastasis dynamics. Cancer Res (2024) 84 (6_Supplement): 1501.
  • Enhancement of Chondrogenic Markers by Exosomes Derived from Cultured Human Synovial Fluid-Derived Cells: A Comparative Analysis of 2D and 3D Conditions. Biomedicines. 2023 Nov 25; 11(12).. View in PubMed
  • Editorial Expression of Concern: MNK kinases facilitate c-myc IRES activity in rapamycin-treated multiple myeloma cells. Oncogene. 2023 10; 42(41):3088.. View in PubMed
  • Targeting Skeletal Muscle Dysfunction With L-Carnitine for the Treatment of Patients With Chronic Obstructive Pulmonary Disease. In Vivo. 2023 Jul-Aug; 37(4):1399-1411.. View in PubMed
  • Successful Phytotherapy for Acute Refractory Radiation Cystitis in a Cervical Cancer Patient: A Case Report. Cancer Diagn Progn. 2023 May-Jun; 3(3):383-386.. View in PubMed
  • Nowarta110 Topical Versus Placebo for the Treatment of Plantar Warts: A Phase I/II Randomized Controlled Clinical Trial. Anticancer Res. 2023 May; 43(5):2025-2030.. View in PubMed
  • Efficacy and Tolerability of Ich Nieu Khang Dietary Supplement for Overactive Bladder. J Med Food. 2023 Apr; 26(4):262-269.. View in PubMed
  • Efficacy of Phytotherapy as Nutritional Supplements in Patients with Refractory Immune Thrombocytopenia. 2023.
  • The Rationality of Implementation of Dimethyl Sulfoxide as Differentiation-inducing Agent in Cancer Therapy. Cancer Diagn Progn. 2023 Jan-Feb; 3(1):1-8.. View in PubMed
  • Preoperative Determination of the Size of the Semitendinosus and Gracilis Tendon by Multidetector Row CT Scanner for Anterior Cruciate Ligament Reconstruction. J Knee Surg. 2022 Dec; 35(14):1556-1562.. View in PubMed
  • Targeting the untargetable: RB1-deficient tumours are vulnerable to Skp2 ubiquitin ligase inhibition. Br J Cancer. 2022 10; 127(6):969-975.. View in PubMed
  • Successful phytotherapy for a patient with severe immune thrombocytopenia and failed with corticosteroids, azathioprine, eltrombopag, and platelet transfusion – A case report. Explore (NY). 2022 Sep-Oct; 18(5):601-603.. View in PubMed
  • Corrigendum to “Zinc salicylate reduces airway smooth muscle cells remodelling by blocking mTOR and activating p21(waf1/cip1)” [Journal of nutritional biochemistry 89 (2021) 108563]. J Nutr Biochem. 2021 Dec; 98:108822.. View in PubMed
  • Application of Dimethyl Sulfoxide as a Therapeutic Agent and Drug Vehicle for Eye Diseases. J Ocul Pharmacol Ther. 2021 Oct; 37(8):441-451.. View in PubMed
  • A Case Report Describing Pre-operative Contouring of an Orthopedic Implant using a 3D-Printed Patient-specific Model. J Orthop Case Rep. 2021 Jun; 11(6):27-31.. View in PubMed
  • Zinc salicylate reduces airway smooth muscle cells remodelling by blocking mTOR and activating p21(Waf1/Cip1). J Nutr Biochem. 2021 03; 89:108563.. View in PubMed
  • Micronutrient zinc roles in adjunctive therapy for COVID-19 by enhancing patients immunoregulation and tolerance to the pathogen. 2021; 3(32):149-157.
  • PEGylated Coating Affects DBM Osteoinductivity In Vivo by Changing Inflammatory Responses. ACS Appl Bio Mater. 2020 Dec 21; 3(12):8722-8730.. View in PubMed
  • Opinions on the current pandemic of COVID-19: Use functional food to boost our immune functions. J Infect Public Health. 2020 Dec; 13(12):1811-1817.. View in PubMed
  • Possible application of high-dose vitamin C in the prevention and therapy of coronavirus infection. J Glob Antimicrob Resist. 2020 12; 23:256-262.. View in PubMed
  • A possible application of hinokitiol as a natural zinc ionophore and anti-infective agent for the prevention and treatment of COVID-19 and viral infections. Med Hypotheses. 2020 Dec; 145:110333.. View in PubMed
  • Zinc sulfide nanoparticles improve skin regeneration. Nanomedicine. 2020 10; 29:102263.. View in PubMed
  • Nattospes as Effective and Safe Functional Supplements in Management of Stroke. J Med Food. 2020 Aug; 23(8):879-885.. View in PubMed
  • Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation. Cell Commun Signal. 2019 03 18; 17(1):25.. View in PubMed
  • Treatment of Nephroblastoma in Developing Countries – Experience from a Single Center in Vietnam with NWTS 5 and SIOP 2001 Protocols. 2019.
  • Nutritional Supplement “Bao Khi Khang” as an Adjuvant Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease. J Med Food. 2018 Oct; 21(10):1053-1059.. View in PubMed
  • Detection of in vivo hepatitis B virus surface antigen mutations-A comparison of four routine screening assays. J Viral Hepat. 2018 10; 25(10):1132-1138.. View in PubMed
  • Effects of Trang Phuc Linh Plus-Food Supplement on Irritable Bowel Syndrome Induced by Mustard Oil. J Med Food. 2017 Apr; 20(4):385-391.. View in PubMed
  • Non invasive imaging assessment of the biodistribution of GSK2849330, an ADCC and CDC optimized anti HER3 mAb, and its role in tumor macrophage recruitment in human tumor-bearing mice. PLoS One. 2017; 12(4):e0176075.. View in PubMed
  • The effect of bone morphogenetic protein-2 on osteosarcoma metastasis. PLoS One. 2017; 12(3):e0173322.. View in PubMed
  • LRP5 Signaling in Osteosarcomagenesis: a Cautionary Tale of Translation from Cell Lines to Tumors. Transl Oncol. 2016 Oct; 9(5):438-444.. View in PubMed
  • Zinc as a possible preventive and therapeutic agent in pancreatic, prostate, and breast cancer. Eur J Cancer Prev. 2016 09; 25(5):457-61.. View in PubMed
  • Therapeutic potential of targeting IRES-dependent c-myc translation in multiple myeloma cells during ER stress. Oncogene. 2016 Feb 25; 35(8):1015-24.. View in PubMed
  • From competency to dormancy: a 3D model to study cancer cells and drug responsiveness. J Transl Med. 2016 Feb 04; 14:38.. View in PubMed
  • Acidosis and Formaldehyde Secretion as a Possible Pathway of Cancer Pain and Options for Improved Cancer Pain Control. J Pain Palliat Care Pharmacother. 2015 Sep; 29(3):276-80.. View in PubMed
  • Palliative treatment for advanced biliary adenocarcinomas with combination dimethyl sulfoxide-sodium bicarbonate infusion and S-adenosyl-L-methionine. J Pain Palliat Care Pharmacother. 2014 Sep; 28(3):206-11.. View in PubMed
  • Wnt signaling in castration-resistant prostate cancer: implications for therapy. Am J Clin Exp Urol. 2014 Apr 15; 2(1):27-44.. View in PubMed
  • Surgical techniques for spinopelvic reconstruction following total sacrectomy: a systematic review. Eur Spine J. 2014 Feb; 23(2):305-19.. View in PubMed
  • Assessment of the Effectiveness of Ich Tam Khang as a Supportive Therapy for Chronic Heart Failure. 2014; 116-121.
  • Dietary feeding of Flavokawain A, a Kava chalcone, exhibits a satisfactory safety profile and its association with enhancement of phase II enzymes in mice. Toxicol Rep. 2014; 1:2-11.. View in PubMed
  • Vascular tumor in metal-on-polyethylene THA requiring hemipelvectomy. Orthopedics. 2013 Jul; 36(7):e974-7.. View in PubMed
  • Flavokawain B, a kava chalcone, induces apoptosis in synovial sarcoma cell lines. J Orthop Res. 2012 Jul; 30(7):1045-50.. View in PubMed
  • Dimethyl sulfoxide-sodium bicarbonate infusion for palliative care and pain relief in patients with metastatic prostate cancer. J Pain Palliat Care Pharmacother. 2011; 25(4):350-5.. View in PubMed
  • Dimethyl sulfoxide and sodium bicarbonate in the treatment of refractory cancer pain. J Pain Palliat Care Pharmacother. 2011; 25(1):19-24.. View in PubMed
  • Dimethyl sulfoxide as an excitatory modulator and its possible role in cancer pain management. Inflamm Allergy Drug Targets. 2010 Sep; 9(4):306-12.. View in PubMed
  • Lactobacillus rhamnosus cell lysate in the management of resistant childhood atopic eczema. Inflamm Allergy Drug Targets. 2010 Jul; 9(3):192-6.. View in PubMed
  • The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition. Mol Cancer. 2010 Jun 23; 9:162.. View in PubMed
  • Treating asthma as a neuroelectrical disorder. Inflamm Allergy Drug Targets. 2010 Jun; 9(2):130-4.. View in PubMed
  • Polymorphisms and methylation of the reduced folate carrier in osteosarcoma. Clin Orthop Relat Res. 2008 Sep; 466(9):2046-51.. View in PubMed
  • Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier. BMC Cancer. 2008 May 01; 8:124.. View in PubMed
  • Neurobiological effects of melatonin as related to cancer. Eur J Cancer Prev. 2007 Dec; 16(6):511-6.. View in PubMed
  • New approach in asthma treatment using excitatory modulator. Phytother Res. 2007 Jun; 21(6):554-7.. View in PubMed
  • The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate. Clin Cancer Res. 2007 May 01; 13(9):2557-67.. View in PubMed
  • Hypothesis of the cause and development of neoplasms. Eur J Cancer Prev. 2007 Feb; 16(1):55-61.. View in PubMed
  • Restoration of cellular energetic balance with L-carnitine in the neuro-bioenergetic approach for cancer prevention and treatment. Med Hypotheses. 2007; 69(2):262-72.. View in PubMed
  • Neuro-bioenergetic concepts in cancer prevention and treatment. Med Hypotheses. 2007; 68(4):832-43.. View in PubMed
  • Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis. Med Hypotheses. 2006; 67(5):1042-51.. View in PubMed
  • Periprosthetic soft tissue recurrence of chondroblastoma after attempted en bloc excision from the proximal humerus. Skeletal Radiol. 2006 Jan; 35(1):53-7.. View in PubMed
  • Refractory idiopathic thrombocytopenic purpura: An integrated approach to treatment. 2003; 2(18):77-82.
  • Aqueous ethanolic extract of St. John’s wort (Hypericum perforatum L.) induces growth inhibition and apoptosis in human malignant cells in vitro. Pharmazie. 2002 May; 57(5):323-31.. View in PubMed
  • [New combination therapies in hematological malignancies]. Gan To Kagaku Ryoho. 2000 Mar; 27(3):388-94.. View in PubMed

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