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Babak Moghimi

Assistant Professor of Clinical Pediatrics and Medicine

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Email [email protected]
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Publications

  • Extracellular Matrix Topography Drives Adrenergic to Mesenchymal Transition in Neuroblastoma. Adv Mater. 2025 Sep; 37(37):e2501526.. View in PubMed
  • CD33-CD123 IF-THEN Gating Reduces Toxicity while Enhancing the Specificity and Memory Phenotype of AML-Targeting CAR-T Cells. Blood Cancer Discov. 2025 Jan 08; 6(1):55-72.. View in PubMed
  • Impact of FilmArray™ Respiratory Panel testing on the clinical management of pediatric bone marrow transplant patients. Eur J Clin Microbiol Infect Dis. 2022 Mar; 41(3):395-405.. View in PubMed
  • Preclinical assessment of the efficacy and specificity of GD2-B7H3 SynNotch CAR-T in metastatic neuroblastoma. Nat Commun. 2021 01 21; 12(1):511.. View in PubMed
  • Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma. Oncoimmunology. 2021 01 04; 10(1):1838140.. View in PubMed
  • High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model. Cancer Immunol Res. 2018 01; 6(1):36-46.. View in PubMed
  • Immune tolerance induction to factor IX through B cell gene transfer: TLR9 signaling delineates between tolerogenic and immunogenic B cells. Mol Ther. 2014 Jun; 22(6):1139-1150.. View in PubMed
  • Induction of tolerance to factor VIII by transient co-administration with rapamycin. J Thromb Haemost. 2011 Aug; 9(8):1524-33.. View in PubMed
  • The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver. Blood. 2011 Jun 16; 117(24):6459-68.. View in PubMed
  • High Efficiency Ex Vivo Gene Transfer to Primary Murine B Cells Using Plasmid or Viral Vectors. J Genet Syndr Gene Ther. 2011 Mar 15; 2(103).. View in PubMed
  • Prevention and Reversal of Antibody Responses Against Factor IX in Gene Therapy for Hemophilia B. Front Microbiol. 2011; 2:244.. View in PubMed
  • Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice. Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15):7101-6.. View in PubMed
  • Defective erythropoiesis in transgenic mice expressing dominant-negative upstream stimulatory factor. Mol Cell Biol. 2009 Nov; 29(21):5900-10.. View in PubMed
  • Impact of the underlying mutation and the route of vector administration on immune responses to factor IX in gene therapy for hemophilia B. Mol Ther. 2009 Oct; 17(10):1733-42.. View in PubMed
  • Calpeptin increases the activity of upstream stimulatory factor and induces high level globin gene expression in erythroid cells. J Biol Chem. 2009 Jul 24; 284(30):20130-5.. View in PubMed
  • Locus control region mediated regulation of adult beta-globin gene expression. J Cell Biochem. 2008 Sep 01; 105(1):9-16.. View in PubMed
  • Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene. Mol Cell Biol. 2008 Mar; 28(5):1584-95.. View in PubMed
  • Recruitment of coregulator complexes to the beta-globin gene locus by TFII-I and upstream stimulatory factor. FEBS J. 2007 Dec; 274(23):6065-73.. View in PubMed
  • The cypriot and Iranian National Mutation Frequency Databases. Hum Mutat. 2006 Jun; 27(6):598-9.. View in PubMed
  • 14C-urea breath test in patients undergoing anti-tuberculosis therapy. World J Gastroenterol. 2005 Mar 21; 11(11):1712-4.. View in PubMed
  • Androgen-induced cerebral venous sinus thrombosis in a young body builder: case report. BMC Neurol. 2004 Dec 03; 4(1):22.. View in PubMed
  • Hb Dhonburi (Neapolis) [beta126(H4)Val–>Gly] identified in a family from northern Iran. Hemoglobin. 2004; 28(4):353-6.. View in PubMed
  • The Iranian Human Mutation Gene Bank: a data and sample resource for worldwide collaborative genetics research. Hum Mutat. 2003 Feb; 21(2):146-50.. View in PubMed
  • An Iranian family with Alzheimer’s disease caused by a novel APP mutation (Thr714Ala). Neurology. 2002 May 28; 58(10):1574-5.. View in PubMed

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