Keck School Faculty

Benjamin Yixing Xu

Benjamin Yixing Xu

Assistant Professor Of Clinical Ophthalmology
Director of Inpatient Ophthalmology Service
Ophthalmology
HC4 3610 1450 San Pablo Street Health Sciences Campus Los Angeles

University of Southern California: Resident Teaching Award, 2016

: Medical Knowledge Award, 2015

: Dr. Alfred P. Steiner Dean's Day Research Award, 2011

: MD/PhD Student Research Symposium Award, 2009

: Columbia University Vision Sciences NEI Training Grant, 2008-2009

: MD/PhD Student Research Symposium Award, 2008

: NIH Medical Scientist Training Program Training Grant, 2004-2008

Racial and Sociodemographic Disparities in the Detection of Narrow Angles before Detection of Primary Angle-Closure Glaucoma in the United States Ophthalmol Glaucoma. 2022 Jul-Aug; 5(4):388-395. . View in PubMed

Angle closure extent, anterior segment dimensions and intraocular pressure Br J Ophthalmol. 2022 Mar 02. . View in PubMed

Optimal number and orientation of anterior segment OCT images to measure ocular biometric parameters in angle closure eyes: the Chinese American Eye Study Br J Ophthalmol. 2022 Jan 21. . View in PubMed

Intrasession Repeatability and Intersession Reproducibility of Macular Vessel Parameters on Optical Coherence Tomography Angiography in Glaucomatous and Non-Glaucomatous Eyes Curr Eye Res. 2022 07; 47(7):1068-1076. . View in PubMed

Visual Field Loss Impacts Vision-Specific Quality of Life by Race and Ethnicity: The Multiethnic Ophthalmology Cohorts of California Study Ophthalmology. 2022 06; 129(6):668-678. . View in PubMed

Ocular Biometric Determinants of Dark-to-Light Change in Angle Width: The Chinese American Eye Study Am J Ophthalmol. 2022 05; 237:183-192. . View in PubMed

Ocular Biometric Risk Factors for Progression of Primary Angle Closure Disease: The Zhongshan Angle Closure Prevention Trial Ophthalmology. 2022 03; 129(3):267-275. . View in PubMed

Assessing accommodative presbyopic biometric changes of the entire anterior segment using single swept-source OCT image acquisitions Eye (Lond). 2022 01; 36(1):119-128. . View in PubMed

Wedge Defects on Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma: Prevalence and Associated Clinical Factors J Glaucoma. 2022 04 01; 31(4):242-249. . View in PubMed

5 by 4. 5?mm Peripapillary Optical Coherence Tomography Angiography Scans in Glaucoma and Non-Glaucoma Eyes. J Glaucoma. 2022 09 01; 31(9):773-782. . View in PubMed

Response to Comment on Gange et alIncidence of Proliferative Diabetic Retinopathy and Other Neovascular Sequelae at 5 Years Following Diagnosis of Type 2 Diabetes. Diabetes Care 2021;44:2518-2526. Diabetes Care. 2022 03 01; 45(3):e61-e62. . View in PubMed

Surgical Outcomes of Transposition Surgery for the Correction of Large-Angle Strabismus J Neuroophthalmol. 2021 Dec 01; 41(4):e806-e814. . View in PubMed

Generalisability and performance of an OCT-based deep learning classifier for community-based and hospital-based detection of gonioscopic angle closure Br J Ophthalmol. 2021 Oct 20. . View in PubMed

Anterior segment biometric measurements explain misclassifications by a deep learning classifier for detecting gonioscopic angle closure Br J Ophthalmol. 2021 Oct 06. . View in PubMed

Differences in Ocular Biometric Measurements among Subtypes of Primary Angle Closure Disease: The Chinese American Eye Study Ophthalmol Glaucoma. 2021 Mar-Apr; 4(2):224-231. . View in PubMed

Steps to Measurement Floor of an Optical Microangiography Device in Glaucoma Am J Ophthalmol. 2021 11; 231:58-69. . View in PubMed

Incidence of Proliferative Diabetic Retinopathy and Other Neovascular Sequelae at 5 Years Following Diagnosis of Type 2 Diabetes Diabetes Care. 2021 11; 44(11):2518-2526. . View in PubMed

Intrasession repeatability and intersession reproducibility of peripapillary OCTA vessel parameters in non-glaucomatous and glaucomatous eyes Br J Ophthalmol. 2021 11; 105(11):1534-1541. . View in PubMed

Hemiretinal Asymmetry in Peripapillary Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes Am J Ophthalmol. 2021 10; 230:156-165. . View in PubMed

Impact of Visual Field Loss on Vision-Specific Quality of Life in African Americans: The African American Eye Disease Study Am J Ophthalmol. 2021 09; 229:52-62. . View in PubMed

Anatomic Changes and Predictors of Angle Widening after Laser Peripheral Iridotomy: The Zhongshan Angle Closure Prevention Trial Ophthalmology. 2021 08; 128(8):1161-1168. . View in PubMed

Glaucoma Expert-Level Detection of Angle Closure in Goniophotographs With Convolutional Neural Networks: The Chinese American Eye Study Am J Ophthalmol. 2021 06; 226:100-107. . View in PubMed

Rates of Eye Care and Diabetic Eye Disease among Insured Patients with Newly Diagnosed Type 2 Diabetes Ophthalmol Retina. 2021 02; 5(2):160-168. . View in PubMed

Relationship Between Macular Vessel Density and Total Retinal Blood Flow in Primary Open-angle Glaucoma J Glaucoma. 2021 08 01; 30(8):666-671. . View in PubMed

Effect of Angle Narrowing on Sectoral Variation of Anterior Chamber Angle Width: The Chinese American Eye Study Ophthalmol Glaucoma. 2020 Mar-Apr; 3(2):130-138. . View in PubMed

Ocular Biometric Determinants of Anterior Chamber Angle Width in Chinese Americans: The Chinese American Eye Study Am J Ophthalmol. 2020 12; 220:19-26. . View in PubMed

A Randomized Controlled Trial Comparing Subconjunctival Injection to Direct Scleral Application of Mitomycin C in Trabeculectomy Am J Ophthalmol. 2020 12; 220:45-52. . View in PubMed

Clinical Utility of Triplicate En Face Image Averaging for Optical Coherence Tomography Angiography in Glaucoma and Glaucoma Suspects J Glaucoma. 2020 09; 29(9):823-830. . View in PubMed

Vessel density and retinal nerve fibre layer thickness following acute primary angle closure Br J Ophthalmol. 2020 08; 104(8):1103-1108. . View in PubMed

Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices Transl Vis Sci Technol. 2020 08; 9(9):14. . View in PubMed

Deep Neural Network for Scleral Spur Detection in Anterior Segment OCT Images: The Chinese American Eye Study Transl Vis Sci Technol. 2020 03; 9(2):18. . View in PubMed

Age- and refraction-related changes in anterior segment anatomical structures measured by swept-source anterior segment OCT PLoS One. 2020; 15(10):e0240110. . View in PubMed

Surgical Management of Primary Angle-Closure Disease-Why Less Is More JAMA Ophthalmol. 2019 Oct 01; 137(10):1113-1114. . View in PubMed

Anterior Segment Optical Coherence Tomography: Applications for Clinical Care and Scientific Research Asia Pac J Ophthalmol (Phila). 2019 Apr 25. . View in PubMed

Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study Transl Vis Sci Technol. 2019 Mar; 8(2):5. . View in PubMed

Deep Learning Classifiers for Automated Detection of Gonioscopic Angle Closure Based on Anterior Segment OCT Images Am J Ophthalmol. 2019 12; 208:273-280. . View in PubMed

Systemic Determinants of Peripapillary Vessel Density in Healthy African Americans: The African American Eye Disease Study Am J Ophthalmol. 2019 11; 207:240-247. . View in PubMed

Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries J Glaucoma. 2019 05; 28(5):465-472. . View in PubMed

Ocular Determinants of Peripapillary Vessel Density in Healthy African Americans: The African American Eye Disease Study Invest Ophthalmol Vis Sci. 2019 08 01; 60(10):3368-3373. . View in PubMed

Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography Transl Vis Sci Technol. 2018 Nov; 7(6):33. . View in PubMed

Correlation between Intraocular Pressure and Angle Configuration Measured by OCT: The Chinese American Eye Study Ophthalmol Glaucoma. 2018 Nov-Dec; 1(3):158-166. . View in PubMed

Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters J Glaucoma. 2018 01; 27(1):16-21. . View in PubMed

Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices J Glaucoma. 2017 Nov; 26(11):974-979. . View in PubMed

Aqueous Angiography: Aqueous Humor Outflow Imaging in Live Human Subjects Ophthalmology. 2017 08; 124(8):1249-1251. . View in PubMed

Benefit of Measuring Anterior Segment Structures Using an Increased Number of Optical Coherence Tomography Images: The Chinese American Eye Study Invest Ophthalmol Vis Sci. 2016 11 01; 57(14):6313-6319. . View in PubMed

The postsaccadic unreliability of gain fields renders it unlikely that the motor system can use them to calculate target position in space Neuron. 2012 Dec 20; 76(6):1201-9. . View in PubMed

Dr. Xu attended Yale University where he graduated cum laude with a bachelor of science in biomedical engineering. He received his MD and PhD degrees from Columbia University where he was part of the NIH-sponsored Medical Scientist Training Program. He completed a well-received thesis studying how the brain uses eye position signals to coordinate accurate eye movements. Dr. Xu completed his residency in ophthalmology at the LAC+USC Medical Center and USC Roski Eye Institute, where he served as Chief Resident and was recognized for his academic and teaching achievements. He completed his glaucoma fellowship with Dr. Robert Weinreb at the UCSD Shiley Eye Institute and Hamilton Glaucoma Center.

Dr. Xu’s primary research interest is preventing vision loss and blindness in patients at risk for angle closure glaucoma (ACG), a common type of glaucoma. His research focuses on studying the pathophysiology of ACG and improving the care of angle closure patients. Dr. Xu collaborates with Dr. Rohit Varma on his population-based eye studies such as the Chinese American Eye Study to identify risk factors for ACG and other ocular diseases. Dr. Xu also uses advanced anterior segment imaging modalities including anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) to study the physiological and biomechanical properties of intraocular structures and aqueous outflow pathways. Finally, Dr. Xu works on designing biomedical devices to assess the function of anterior segment structures, such as the iris and trabecular meshwork.
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