Berenice A. Benayoun

Bérénice Benayoun, Ph.D., is an Assistant Professor of Gerontology and Biological Sciences at USC Leonard Davis School of Gerontology. She holds secondary appointments in the Department of Molecular and Computational Biology Department of the USC Dornsife College of Letters, Arts and Sciences and the USC Norris Comprehensive Cancer Center. She joined the USC faculty in 2017.

Dr. Benayoun received her undergraduate and graduate degrees at the École Normale Supérieure de Paris and Université Paris Diderot-Paris 7 in Paris, France. Her PhD work focused on a transcription factor whose mutations lead to a human syndrome associated to premature menopause. During her post-doctoral training, she identified a new key chromatin signature of cell identity and transcriptional consistency, which is partially remodeled during aging. This work has raised important questions about the stability of cellular identity throughout life. Her lab’s current research focuses on epigenome and transcriptome remodeling with aging in vertebrates, how these changes interact with overlooked cues such as biological sex, and the roles that these changes can play in the aging process. Her lab is also one of the pioneering labs in the development of a naturally short-lived vertebrate as a new model for aging research, the African turquoise killifish Nothobranchius furzeri.

Dr. Benayoun was named a 2020 Pew Biomedical Scholar and the 2021 Nathan Shock new Investigator. Since starting as faculty, she has also been the recipient of the 2019 Rosalind Franklin Young Investigator Award in Mammalian Genetics, of a Junior Faculty Award from the American Federation of Aging Research, of Junior Scholar Award from the Global Consortium for Reproductive Longevity and Equality GCRLE. She also serves on the editorial boards of scientific journals Translational Medicine of Aging, Journals of Gerontology series A: Biological Sciences and eLife.

• AGHE Rising Star Early Career Faculty Award, 2023
• USC Mentoring Award recipients for Faculty Mentoring Undergraduate Students, 2023
• Rising Star in Reproductive Biology (awarded by the Society for the Study of Reproduction), 2023
• Nathan Shock New Investigator award (awarded by the Gerontology Society of America), 2021
• Rosalind Franklin Young Investigator Award in Mammalian Genetics, 2019

• Universite Paris Diderot-Paris 7, Paris, France — PhD — 2/2011 — Genetics, reproduction
• Stanford University, Palo Alto, CA — postdoc — 7/2017 — Aging biology
• ENS/Universite Paris Diderot-Paris 7, Paris, France — MSc — 7/2007 — Genetics
• ENS/Universite Paris Diderot-Paris 7, Paris, France — BSc — 7/2005 — Genetics, Cell Biology

• Single-cell exploration of ovarian aging across vertebrates
  CZI · May 1, 2023 – Sep 30, 2024 · Role: PI
• Deciphering hormonal regulation of neutrophil biology
  NIH · R01AG076433 · Sep 30, 2022 – May 31, 2026 · Role: Principal Investigator
• Understanding the regulation and impact of transposable elements in Vertebrate health and disease
  NIH · R35GM142395 · Aug 20, 2021 – Jun 30, 2026 · Role: Principal Investigator
• Simons Collaboration on Plasticity in the Aging Brain
  Simons Foundation · Oct 1, 2020 – Sep 30, 2025
• Transposable elements as drivers of normal and accelerated aging in Vertebrates
  NIH · R21AG063739 · Aug 1, 2019 – Mar 31, 2021 · Role: Principal Investigator
• Regulation of transcriptional consistency by broad H3K4me3 domains in young cells and during aging
  NIH · R00AG049934 · Apr 15, 2015 – May 31, 2021 · Role: Principal Investigator
• Regulation of transcriptional consistency by broad H3K4me3 domains in young cells and during aging
  NIH · K99AG049934 · Apr 15, 2015 – Jul 14, 2017 · Role: Principal Investigator

• Aging
• Macrophages
• Neutrophils
• African turquoise killifish
• Sex-differences
• Transposons
• Big Data

• Finch, Caleb
• Longo, Valter
• Crimmins, Eileen
• Thompson, Paul
• Curran, Sean
• Cohen, Pinchas