Biju Thomas, PhD

Associate Professor of Research Ophthalmology

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Publications

  • Scaling up polarized RPE cell supernatant production on parylene membrane Exp Eye Res. 2024 Jan 17; 109789. . View in PubMed
  • Author Correction: An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model Sci Rep. 2023 Oct 23; 13(1):18120. . View in PubMed
  • Polarized RPE Secretome Preserves Photoreceptors in Retinal Dystrophic RCS Rats Cells. 2023 Jun 22; 12(13). . View in PubMed
  • Non-Invasive Hybrid Ultrasound Stimulation of Visual Cortex In Vivo Bioengineering (Basel). 2023 May 10; 10(5). . View in PubMed
  • Ultrasound Concave 2-D Ring Array for Retinal Stimulation IEEE Trans Ultrason Ferroelectr Freq Control. 2023 11; 70(11):1527-1535. . View in PubMed
  • An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model Sci Rep. 2023 09 23; 13(1):15924. . View in PubMed
  • Development of a Surgical Technique for Subretinal Implants in Rats J Vis Exp. 2022 Dec 02; (190). . View in PubMed
  • Ultrasound Retinal Stimulation: A Mini-Review of Recent Developments IEEE Trans Ultrason Ferroelectr Freq Control. 2022 12; 69(12):3224-3231. . View in PubMed
  • A New Optokinetic Testing Method to Measure Rat Vision J Vis Exp. 2022 07 27; (185). . View in PubMed
  • Noninvasive Ultrasound Retinal Stimulation for Vision Restoration at High Spatiotemporal Resolution BME Front. 2022; 2022:9829316. . View in PubMed
  • Stem Cell-based Treatment Strategies for Degenerative Diseases of the Retina Curr Stem Cell Res Ther. 2022; 17(3):214-225. . View in PubMed
  • Tissue Engineering Strategies for Retina Regeneration Appl Sci (Basel). 2021 Mar; 11(5). . View in PubMed
  • Transcranial Focused Ultrasound for Noninvasive Neuromodulation of the Visual Cortex IEEE Trans Ultrason Ferroelectr Freq Control. 2021 01; 68(1):21-28. . View in PubMed
  • Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo Sci Rep. 2021 03 18; 11(1):6286. . View in PubMed
  • Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats Cells. 2021 10 29; 10(11). . View in PubMed
  • Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats Front Neurosci. 2021; 15:752958. . View in PubMed
  • Relation of Retinal Oxygen Measures to Electrophysiology and Survival Indicators after Permanent, Incomplete Ischemia in Rats Transl Stroke Res. 2020 12; 11(6):1273-1286. . View in PubMed
  • Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction Invest Ophthalmol Vis Sci. 2020 09 01; 61(11):34. . View in PubMed
  • A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells Graefes Arch Clin Exp Ophthalmol. 2018 Nov; 256(11):2113-2125. . View in PubMed
  • Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats Invest Ophthalmol Vis Sci. 2018 05 01; 59(6):2586-2603. . View in PubMed
  • A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration Sci Transl Med. 2018 04 04; 10(435). . View in PubMed
  • Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models Stem Cells Int. 2017; 2017:9428176. . View in PubMed
  • Vision Recovery and Connectivity by Fetal Retinal Sheet Transplantation in an Immunodeficient Retinal Degenerate Rat Model Invest Ophthalmol Vis Sci. 2017 01 01; 58(1):614-630. . View in PubMed
  • Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs Graefes Arch Clin Exp Ophthalmol. 2016 Aug; 254(8):1553-1565. . View in PubMed
  • Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats Invest Ophthalmol Vis Sci. 2016 05 01; 57(6):2877-87. . View in PubMed
  • Long-term evaluation of Leber’s hereditary optic neuropathy-like symptoms in rotenone administered rats Neurosci Lett. 2015 Jan 12; 585:171-6. . View in PubMed
  • Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer Invest Ophthalmol Vis Sci. 2013 Jul 26; 54(7):5087-96. . View in PubMed
  • In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance Ophthalmic Surg Lasers Imaging Retina. 2013 Jul-Aug; 44(4):380-4. . View in PubMed
  • A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer Ophthalmic Res. 2012; 48(4):186-91. . View in PubMed
  • Modulatory influence of stimulus parameters on optokinetic head-tracking response Neurosci Lett. 2010 Jul 26; 479(2):92-6. . View in PubMed
  • Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model PLoS One. 2010 Jul 08; 5(7):e11472. . View in PubMed
  • Retinal transplants restore visual responses: trans-synaptic tracing from visually responsive sites labels transplant neurons Eur J Neurosci. 2008 Jul; 28(1):208-20. . View in PubMed
  • BDNF-treated retinal progenitor sheets transplanted to degenerate rats: improved restoration of visual function Exp Eye Res. 2008 Jan; 86(1):92-104. . View in PubMed
  • Structure and function of embryonic rat retinal sheet transplants Curr Eye Res. 2007 Sep; 32(9):781-9. . View in PubMed
  • Revisiting nestin expression in retinal progenitor cells in vitro and after transplantation in vivo Exp Eye Res. 2007 Jun; 84(6):1047-59. . View in PubMed
  • Behavioral evaluation of visual function of rats using a visual discrimination apparatus J Neurosci Methods. 2007 May 15; 162(1-2):84-90. . View in PubMed
  • Visual functional effects of constant blue light in a retinal degenerate rat model Photochem Photobiol. 2007 May-Jun; 83(3):759-65. . View in PubMed
  • Retinal transplants evaluated by optical coherence tomography in photoreceptor degenerate rats J Neurosci Methods. 2006 Mar 15; 151(2):186-93. . View in PubMed
  • Retinal transplantationA treatment strategy for retinal degenerative diseases. Adv Exp Med Biol. 2006; 572:367-76. . View in PubMed
  • Light response differences in the superior colliculus of albino and pigmented rats Neurosci Lett. 2005 Sep 09; 385(2):143-7. . View in PubMed
  • Transsynaptic virus tracing from host brain to subretinal transplants Eur J Neurosci. 2005 Jan; 21(1):161-72. . View in PubMed
  • Optokinetic test to evaluate visual acuity of each eye independently J Neurosci Methods. 2004 Sep 30; 138(1-2):7-13. . View in PubMed
  • Superior colliculus responses to light – preserved by transplantation in a slow degeneration rat model Exp Eye Res. 2004 Jul; 79(1):29-39. . View in PubMed