USC.edu
Are You a Patient?

Bingfei Yu

Assistant Professor of Immunology and Immune Therapeutics and Biomedical Engineering

Image of Bingfei Yu
Is this your profile? Click to edit
Email bingfeiy@usc.edu
CTSI Profile

Overview

Our lab investigates two fundamental aspects of immune system biology: (1) the molecular mechanisms underlying inter-cellular immune recognition, by developing tools to link immune recognition and molecular programming at single-cell resolution and (2) the role of X-chromosome inactivation in immune cells, focusing on how this epigenetic regulation contributes to sex-based differences in immune responses.

Education and Training

  • University of California, San Diego — Ph.D. — 06/2018 — Immunology

Publications

  • Cytokine-mediated intrinsic and extrinsic regulation of anti-tumor adoptive T cell therapy. Cytokine Growth Factor Rev. 2026 Aug; 90:26-38.. View in PubMed
  • Long noncoding RNA regulation of immunity. Nat Immunol. 2026 01; 27(1):16-25.. View in PubMed
  • A metabolic atlas of mouse aging. Cell Metab. 2026 Feb 03; 38(2):399-418.e7.. View in PubMed
  • Tumour priming by ultrasound mechanogenetics for CAR T therapy. Nat Mater. 2026 02; 25(2):310-321.. View in PubMed
  • Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation. Nat Genet. 2025 Aug; 57(8):2062-2073.. View in PubMed
  • T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells. Cell Rep. 2024 06 25; 43(6):114258.. View in PubMed
  • Xist ribonucleoproteins promote female sex-biased autoimmunity. Cell. 2024 02 01; 187(3):733-749.e16.. View in PubMed
  • DNA architectural protein CTCF facilitates subset-specific chromatin interactions to limit the formation of memory CD8+ T cells. Immunity. 2023 05 09; 56(5):959-978.e10.. View in PubMed
  • Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells. bioRxiv. 2023 Mar 22.. View in PubMed
  • Engineered cell entry links receptor biology with single-cell genomics. Cell. 2022 12 22; 185(26):4904-4920.e22.. View in PubMed

Similar People