Bino Varghese, PhD

Associate Professor Of Research Radiology

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Overview

Bino Varghese is an Assistant Professor of Research with expertise in imaging, image processing, quantification and biomechanics. He obtained his B.E. in Medical Electronics from Visveswariah Technological University in 2002 and his Master’s degree in Biomedical Engineering with a focus in imaging and image processing, from the Wright State University at Dayton, Ohio in 2005. In 2010, he received his Ph.D. in Biomedical Sciences from Wright State University. His doctoral dissertation was titled “Quantitative Computed-Tomography Based Bone-Strength Indicators for the Identification of Low Bone-Strength Individuals in a Clinical Environment.”

In Feb 2014, he joined the Department of Radiology at USC as a Research Laboratory Specialist. His current work focuses on investigating the technical feasibility and clinical value of quantifying multi-modal imaging biomarkers across various domains with an aim to maximize data utilization and increase clinical translation.

Awards

  • USC’s Mark and Mary Stevens Neuroimaging and Informatics Institute: Big Data to Knowledge Science Rotations for Advancing Discovery (RoAD-Trip) Award, 2017
     – 2017

Education and Training

  • Visveswariah Technological University, Bangalore, India — BE — 2002 — Medical Electronics
  • Wright State University, Dayton, Ohio — MS — 2005 — Imaging and Image Processing
  • Wright State University, Dayton, Ohio — PhD — 2011 — Biomedical Sciences
  • UCLA, Los Angeles, CA — Postdoctoral — 2012 — Cellular Mechanics

Research Funding

  • Reliability Assessment of CT-based Radiomics Metrics in Tissue Characterization
    USC · Mar 1, 2020 – Feb 28, 2021 · Role: PI
  • Radiomic signature of CD+ T cell infiltration and PD-L1 expression in metastatic renal cell carcinoma
    American Cancer Society · Sep 9, 2019 – Aug 31, 2021 · Role: CoI
  • Characterizing Breast Masses Using an Integrative Framework of Machine Learning and Radiomics
    Wright Foundation · Jul 1, 2019 – Dec 31, 2020 · Role: PI
  • Assessing the role of contrast-enhanced ultrasound and MV FlowTM technology of Samsung RS85 in the evaluation of renal masses
    Samsung · May 1, 2018 – Dec 31, 2020 · Role: CoI

Research Keywords

  • Imaging, quantitative imaging, radiomics, performance assessment, image-processing

Publications

  • Influence of scan mode, tilt, and radiation dose on CT radiomic metrics. J Appl Clin Med Phys. 2026 Jan; 27(1):e70462.. View in PubMed
  • Advancing 1.5T MR imaging: toward achieving 3T quality through deep learning super-resolution techniques. Front Hum Neurosci. 2025; 19:1532395.. View in PubMed
  • Diffusion based multi-domain neuroimaging harmonization method with preservation of anatomical details. Neuroimage. 2025 Aug 01; 316:121297.. View in PubMed
  • Integrated Hyperparameter Optimization with Dimensionality Reduction and Clustering for Radiomics: A Bootstrapped Approach. Multimodal Technol Interact. 2025 May; 9(5).. View in PubMed
  • Editorial: Advances in artificial intelligence and machine learning applications for the imaging of bone and soft tissue tumors. Front Radiol. 2024; 4:1523389.. View in PubMed
  • Artificial intelligence and machine learning applications for the imaging of bone and soft tissue tumors. Front Radiol. 2024; 4:1332535.. View in PubMed
  • Technical and clinical considerations of a physical liver phantom for CT radiomics analysis. J Appl Clin Med Phys. 2024 Apr; 25(4):e14309.. View in PubMed
  • Empowering breast cancer diagnosis and radiology practice: advances in artificial intelligence for contrast-enhanced mammography. Front Radiol. 2023; 3:1326831.. View in PubMed
  • Conditional generative learning for medical image imputation. Sci Rep. 2024 01 02; 14(1):171.. View in PubMed
  • Investigating the role of imaging factors in the variability of CT-based texture analysis metrics. J Appl Clin Med Phys. 2024 Apr; 25(4):e14192.. View in PubMed