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Brian Huang, PhD, MPH

Assistant Professor of Population and Public Health Sciences

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Email brian.huang@usc.edu
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Overview

Dr. Brian Huang is a cancer epidemiologist and an Assistant Professor in the Department of Population and Public Health Sciences at the Keck School of Medicine of USC. His research focuses on the etiologic mechanisms and racial/ethnic disparities of pancreatic, colorectal and lung cancer. Dr. Huang’s work integrates epidemiologic, clinical and multi-omic (e.g., genomic, epigenomic, metabolomic) data from racially/ethnically diverse populations to investigate interethnic differences in the risk and survival of cancer.

Publications

  • Risk Factor Profiles and Elevated Incidence of Pancreatic Cancer in Native Hawaiians. Am J Gastroenterol. 2026 Jan 01; 121(1):274-276.. View in PubMed
  • Alcohol consumption and upper aerodigestive tract squamous cell carcinoma: evidence from 28 prospective cohorts. J Natl Cancer Inst. 2025 Dec 01; 117(12):2598-2611.. View in PubMed
  • Adherence to World Cancer Research Fund/American Institute for Cancer Research Guidelines and Mortality among Participants with Colorectal Cancer in the MEC. Cancer Epidemiol Biomarkers Prev. 2025 Sep 02; 34(9):1558-1565.. View in PubMed
  • A scoping review on per- and poly-fluoroalkyl substances (PFAS) and colorectal cancer: Evidence from in vitro, animal, and epidemiological studies. Environ Int. 2025 Sep; 203:109778.. View in PubMed
  • The Multiethnic Cohort: A Resource for the study of Genetic and non-Genetic Cancer Risk Across Populations. medRxiv. 2025 Jun 11.. View in PubMed
  • Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America. PLoS Med. 2025 May; 22(5):e1004590.. View in PubMed
  • Response to Zhou. Am J Gastroenterol. 2025 Apr 01; 120(4):927-928.. View in PubMed
  • Racial/ethnic differences in risk factors for non-cardia gastric cancer: an analysis of the Multiethnic Cohort (MEC) Study. Cancer Causes Control. 2025 Mar; 36(3):255-263.. View in PubMed
  • Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study. Cell Rep Med. 2024 Dec 17; 5(12):101842.. View in PubMed
  • The Causal Effect of Intrapancreatic Fat Deposition on Acute and Chronic Pancreatitis: A Mendelian Randomization Study. Am J Gastroenterol. 2024 Dec 01; 119(12):2540-2544.. View in PubMed
  • Early COVID-19 Vaccine Initiation and Completion Among Cancer Survivors and Barriers to Vaccine Completion: Implications for Future COVID-19 Vaccination Uptake Rates. Cancer Med. 2024 Nov; 13(22):e70428.. View in PubMed
  • Genetic Evidence for a Causal Link between Intra-Pancreatic Fat Deposition and Pancreatitis: a Mendelian Randomization Study. medRxiv. 2024 Jun 04.. View in PubMed
  • Genetically Determined Circulating Lactase/Phlorizin Hydrolase Concentrations and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study. Nutrients. 2024 Mar 12; 16(6).. View in PubMed
  • Epigenome-wide association study of total nicotine equivalents in multiethnic current smokers from three prospective cohorts. Am J Hum Genet. 2024 03 07; 111(3):456-472.. View in PubMed
  • Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study. Cell Rep Med. 2024 02 20; 5(2):101391.. View in PubMed
  • Genetic Evidence Causally Linking Pancreas Fat to Pancreatic Cancer: A Mendelian Randomization Study. medRxiv. 2023 Apr 26.. View in PubMed
  • The Independent Effect of COVID-19 Vaccinations and Air Pollution Exposure on Risk of COVID-19 Hospitalizations in Southern California. Am J Respir Crit Care Med. 2023 01 15; 207(2):218-221.. View in PubMed
  • The impact of stay-at-home orders on the rate of emergency department child maltreatment diagnoses. Child Abuse Negl. 2022 10; 132:105821.. View in PubMed
  • Ambient Air Pollutant Exposures and COVID-19 Severity and Mortality in a Cohort of Patients with COVID-19 in Southern California. Am J Respir Crit Care Med. 2022 08 15; 206(4):440-448.. View in PubMed
  • Assessment of treatment strategies for stage I non-small cell lung cancer in patients with comorbidities. Lung Cancer. 2022 08; 170:34-40.. View in PubMed
  • Rising Incidence and Racial Disparities of Early-Onset Pancreatic Cancer in the United States, 1995-2018. Gastroenterology. 2022 07; 163(1):310-312.e1.. View in PubMed
  • Ambient air pollution and COVID-19 incidence during four 2020-2021 case surges. Environ Res. 2022 05 15; 208:112758.. View in PubMed
  • Pre-Existing Pancreatitis and Elevated Risks of COVID-19 Severity and Mortality. Gastroenterology. 2022 05; 162(6):1758-1760.e3.. View in PubMed
  • Healthcare Utilization Among Patients Diagnosed with COVID-19 in a Large Integrated Health System. J Gen Intern Med. 2022 03; 37(4):830-837.. View in PubMed
  • Changes in Metabolic Syndrome and Its Implications on the Risk and Racial/Ethnic Disparities of Pancreatic Cancer. Gastroenterology. 2022 02; 162(2):392-394.. View in PubMed
  • The Probability of Lung Cancer in Patients With Incidentally Detected Pulmonary Nodules: Clinical Characteristics and Accuracy of Prediction Models. Chest. 2022 02; 161(2):562-571.. View in PubMed
  • The benefits and harms of adjuvant chemotherapy for non-small cell lung cancer in patients with major comorbidities: A simulation study. PLoS One. 2022; 17(11):e0263911.. View in PubMed
  • Near-roadway air pollution associated with COVID-19 severity and mortality – Multiethnic cohort study in Southern California. Environ Int. 2021 12; 157:106862.. View in PubMed
  • Natural Language Processing to Identify Pulmonary Nodules and Extract Nodule Characteristics From Radiology Reports. Chest. 2021 11; 160(5):1902-1914.. View in PubMed
  • Asthma Disease Status, COPD, and COVID-19 Severity in a Large Multiethnic Population. J Allergy Clin Immunol Pract. 2021 10; 9(10):3621-3628.e2.. View in PubMed
  • Machine Learning for Early Lung Cancer Identification Using Routine Clinical and Laboratory Data. Am J Respir Crit Care Med. 2021 08 15; 204(4):445-453.. View in PubMed
  • Identifying patients with symptoms suspicious for COVID-19 at elevated risk of adverse events: The COVAS score. Am J Emerg Med. 2021 Aug; 46:489-494.. View in PubMed
  • Red meat consumption, cooking mutagens, NAT1/2 genotypes and pancreatic cancer risk in two ethnically diverse prospective cohorts. Int J Cancer. 2021 Apr 12.. View in PubMed
  • Methylation of immune-regulatory cytokine genes and pancreatic cancer outcomes. Epigenomics. 2020 08; 12(15):1273-1285.. View in PubMed
  • New-Onset Diabetes, Longitudinal Trends in Metabolic Markers, and Risk of Pancreatic Cancer in a Heterogeneous Population. Clin Gastroenterol Hepatol. 2020 07; 18(8):1812-1821.e7.. View in PubMed
  • Interethnic differences in pancreatic cancer incidence and risk factors: The Multiethnic Cohort. Cancer Med. 2019 07; 8(7):3592-3603.. View in PubMed
  • Does Providing Positive Airway Pressure for Sleep Apnea Change Health Care Utilization? Med Care. 2018 11; 56(11):901-907.. View in PubMed
  • Polymorphisms in genes related to inflammation and obesity and colorectal adenoma risk. Mol Carcinog. 2018 10; 57(10):1278-1288.. View in PubMed
  • Reduction of Parenteral Opioid Use in Community Emergency Departments Following Implementation of Treatment Guidelines. Acad Emerg Med. 2018 Aug; 25(8):901-910.. View in PubMed
  • Atopic allergic conditions and pancreatic cancer risk: Results from the Multiethnic Cohort Study. Int J Cancer. 2018 05 15; 142(10):2019-2027.. View in PubMed
  • Cachexia, and not obesity, prior to pancreatic cancer diagnosis worsens survival and is negated by chemotherapy. J Gastrointest Oncol. 2018 Feb; 9(1):17-23.. View in PubMed
  • Impact of Integrated Health Care Delivery on Racial and Ethnic Disparities in Pancreatic Cancer. Pancreas. 2018 02; 47(2):221-226.. View in PubMed
  • Implementation of the Canadian CT Head Rule and Its Association With Use of Computed Tomography Among Patients With Head Injury. Ann Emerg Med. 2018 Jan; 71(1):54-63.e2.. View in PubMed
  • Tablet-Based Patient-Centered Decision Support for Minor Head Injury in the Emergency Department: Pilot Study. JMIR Mhealth Uhealth. 2017 Sep 28; 5(9):e144.. View in PubMed
  • Competing Risks for Mortality in Patients With Asymptomatic Pancreatic Cystic Neoplasms: Implications for Clinical Management. Am J Gastroenterol. 2017 Aug; 112(8):1330-1336.. View in PubMed
  • Influence of Statins and Cholesterol on Mortality Among Patients With Pancreatic Cancer. J Natl Cancer Inst. 2017 05; 109(5).. View in PubMed
  • Burden of preoperative cardiovascular disease risk factors on breast cancer surgery outcomes. J Surg Oncol. 2016 Aug; 114(2):144-9.. View in PubMed
  • Impact of statin use on survival in patients undergoing resection for early-stage pancreatic cancer. Am J Gastroenterol. 2015 Aug; 110(8):1233-9.. View in PubMed
  • Stepping toward discharge: Level of ambulation in hospitalized patients. J Hosp Med. 2015 Jun; 10(6):384-9.. View in PubMed
  • Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson’s disease and depression. Mol Psychiatry. 2014 Feb; 19(2):235-42.. View in PubMed
  • Promoting patient-centred care through trainee feedback: assessing residents’ C-I-CARE (ARC) program. BMJ Qual Saf. 2012 Mar; 21(3):225-33.. View in PubMed
  • Correlates and Consequences of Dominance in a Social Rodent. Ethology. 2011; 117(7):573-585.
  • Take only pictures, leave only…fear? The effects of photography on the West Indian anole Anolis cristatellus. Current Zoology. 2011; 57(1):77–82.

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