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Brian Toy, MD

Assistant Professor of Clinical Ophthalmology

Director of Clinical Informatics and Information Technology

Service Chief of the Uveitis and Ocular Inflammation Service

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Phone +1 323 442 6412
Email brian.toy@med.usc.edu
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Overview

Brian Toy, MD, is a vitreoretinal fellow and clinical instructor at the USC Roski Eye Institute. He graduated magna cum laude from the University of California, Berkeley, with a degree in bioengineering, received an MD with distinction from the University of California, San Francisco, and completed a clinical research fellowship at the National Institutes of Health. He completed an internship at Santa Clara Valley Medical Center, a major county healthcare system in the Bay Area, and then completed an ophthalmology residency at Stanford University. Toy’s professional interests include retinal imaging, telemedicine and safety net care, particularly as applied to diabetic retinopathy. Outside of work, he enjoys hiking, skiing, and spending time with friends and family.

Publications

  • Outpatient Oral Doxycycline versus Intravenous Penicillin for Syphilitic Uveitis. Ophthalmology. 2025 Dec; 132(12):1457-1459.. View in PubMed
  • Intravitreal anti-VEGF therapy and risk of limb complications in individuals with diabetic eye disease. Diabetes Res Clin Pract. 2025 Nov; 229:112457.. View in PubMed
  • Longitudinal Trends in Resource Utilization Associated With Newly Diagnosed Primary Angle Closure Glaucoma in the United States. J Glaucoma. 2025 Oct 01; 34(10):776-782.. View in PubMed
  • Uveitis Risk and GLP-1RA Use-Signal, Confounding, or Both? JAMA Ophthalmol. 2025 Oct 01; 143(10):832-833.. View in PubMed
  • Developing Laterality-Specific Computable Phenotypes from Electronic Health Record Data, Employing Treatment-Warranted Diabetic Macular Edema as a Use Case. Ophthalmol Sci. 2025 Sep-Oct; 5(5):100797.. View in PubMed
  • Utility of optometrist referrals for glaucoma evaluation in a young adult population. Clin Exp Optom. 2025 Jun 25; 1-6.. View in PubMed
  • A case of refractory idiopathic retinitis, vasculitis, aneurysms, and neuroretinitis (IRVAN) responsive to infliximab and mycophenolate mofetil. Retin Cases Brief Rep. 2025 Jun 23.. View in PubMed
  • Intraocular Inflammation, Safety Events, and Outcomes After Intravitreal Injection of Ranibizumab, Aflibercept, Brolucizumab, Abicipar Pegol, and Faricimab for nAMD. J Vitreoretin Dis. 2025 Apr 21; 24741264251332515.. View in PubMed
  • Four cases of endogenous Klebsiella endophthalmitis in Los Angeles County: A case series. Taiwan J Ophthalmol. 2025 Apr-Jun; 15(2):313-318.. View in PubMed
  • Purpureocillium lilacinum keratitis in a methamphetamine user: Case report. Taiwan J Ophthalmol. 2025 Apr-Jun; 15(2):308-312.. View in PubMed
  • Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy. JAMA Ophthalmol. 2025 Apr 01; 143(4):304-314.. View in PubMed
  • Relationship Between Chronic Stress Measured by Allostatic Load and Age-Related Macular Degeneration in the All of Us Research Program. Am J Ophthalmol. 2025 Apr; 272:150-160.. View in PubMed
  • Corrigendum to “Practice Patterns and Sociodemographic Disparities in the Clinical Care of Anatomical Narrow Angles in the United States” [American Journal of Ophthalmology Volume 261 (2024) Pages 66-75]. Am J Ophthalmol. 2025 Apr; 272:196.. View in PubMed
  • Implementing a Common Data Model in Ophthalmology: Mapping Structured Electronic Health Record Ophthalmic Examination Data to Standard Vocabularies. Ophthalmol Sci. 2025 Mar-Apr; 5(2):100666.. View in PubMed
  • Outpatient Oral Doxycycline Therapy for Ocular Syphilis. JAMA Netw Open. 2024 Dec 02; 7(12):e2449364.. View in PubMed
  • Clinico-pathologic correlation in ocular sarcoidosis. Am J Ophthalmol Case Rep. 2024 Dec; 36:102220.. View in PubMed
  • Similar Risk of Kidney Failure among Patients with Blinding Diseases Who Receive Ranibizumab, Aflibercept, and Bevacizumab: An Observational Health Data Sciences and Informatics Network Study. Ophthalmol Retina. 2024 Aug; 8(8):733-743.. View in PubMed
  • Patterns and Disparities in Recorded Gonioscopy During Initial Glaucoma Evaluations in the United States. Am J Ophthalmol. 2024 08; 264:90-98.. View in PubMed
  • A CASE OF HERPES SIMPLEX VIRUS AND CYTOMEGALOVIRUS RETINITIS COINFECTION. Retin Cases Brief Rep. 2024 Jul 01; 18(4):451-454.. View in PubMed
  • Variations in Electronic Health Record-Based Definitions of Diabetic Retinopathy Cohorts: A Literature Review and Quantitative Analysis. Ophthalmol Sci. 2024 Jul-Aug; 4(4):100468.. View in PubMed
  • Practice Patterns and Sociodemographic Disparities in the Clinical Care of Anatomical Narrow Angles in the United States. Am J Ophthalmol. 2024 05; 261:66-75.. View in PubMed
  • Implementation of a pilot teleretinal screening protocol for hydroxychloroquine retinopathy in a Los Angeles County safety net clinic. J Telemed Telecare. 2023 Sep; 29(8):648-656.. View in PubMed
  • Infectious Uveitis: Conversations with the Experts. Ocul Immunol Inflamm. 2023 09; 31(7):1333-1341.. View in PubMed
  • Mitigating Hydroxychloroquine Toxicity with a Clinical Decision Support Tool. Ophthalmology. 2023 08; 130(8):874-876.. View in PubMed
  • Rates and Patterns of Diagnostic Conversion from Anatomical Narrow Angle to Primary Angle-Closure Glaucoma in the United States. Ophthalmol Glaucoma. 2023 Mar-Apr; 6(2):169-176.. View in PubMed
  • PURTSCHER-LIKE RETINOPATHY ASSOCIATED WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME: CASE REPORT AND REVIEW OF OUTCOMES. Retin Cases Brief Rep. 2023 Mar 01; 17(2):154-159.. View in PubMed
  • Racial and Sociodemographic Disparities in the Detection of Narrow Angles before Detection of Primary Angle-Closure Glaucoma in the United States. Ophthalmol Glaucoma. 2022 Jul-Aug; 5(4):388-395.. View in PubMed
  • Response to Comment on Gange et al. Incidence of Proliferative Diabetic Retinopathy and Other Neovascular Sequelae at 5 Years Following Diagnosis of Type 2 Diabetes. Diabetes Care 2021;44:2518-2526. Diabetes Care. 2022 03 01; 45(3):e61-e62.. View in PubMed
  • A Smartphone-Based Near-Vision Testing System: Design, Accuracy, and Reproducibility Compared With Standard Clinical Measures. Ophthalmic Surg Lasers Imaging Retina. 2022 02; 53(2):79-84.. View in PubMed
  • Factors Affecting Ophthalmology Trainees to Pursue Vitreoretinal Surgery Fellowship. J Acad Ophthalmol (2017). 2022 Jan; 14(1):e110-e119.. View in PubMed
  • Incidence of Proliferative Diabetic Retinopathy and Other Neovascular Sequelae at 5 Years Following Diagnosis of Type 2 Diabetes. Diabetes Care. 2021 11; 44(11):2518-2526.. View in PubMed
  • Comparison of Telemedicine Screening of Diabetic Retinopathy by Mydriatic Smartphone-Based vs Nonmydriatic Tabletop Camera-Based Fundus Imaging. J Vitreoretin Dis. 2021 May; 5(3):199-207.. View in PubMed
  • Rates of Eye Care and Diabetic Eye Disease among Insured Patients with Newly Diagnosed Type 2 Diabetes. Ophthalmol Retina. 2021 02; 5(2):160-168.. View in PubMed
  • Big Data-Based Epidemiology of Uveitis and Related Intraocular Inflammation. Asia Pac J Ophthalmol (Phila). 2021 Jan-Feb 01; 10(1):60-62.. View in PubMed
  • Quantifying Subclinical and Longitudinal Microvascular Changes Following Episcleral Plaque Brachytherapy Using Spectral Domain-Optical Coherence Tomography Angiography. J Vitreoretin Dis. 2020 Nov; 4(6):499-508.. View in PubMed
  • Multimodal imaging reveals pathological edges of disease activity in tuberculosis-associated multifocal serpiginoid chorioiditis. Am J Ophthalmol Case Rep. 2020 Sep; 19:100766.. View in PubMed
  • Interleukins and cytokine biomarkers in uveitis. Indian J Ophthalmol. 2020 09; 68(9):1750-1763.. View in PubMed
  • Retinal capillary hemangioblastomatosis and renal tumor in Von Hippel-Lindau disease. Am J Ophthalmol Case Rep. 2020 Jun; 18:100718.. View in PubMed
  • Assessment of Eye Disease and Visual Impairment in the Nursing Home Population Using Mobile Health Technology. Ophthalmic Surg Lasers Imaging Retina. 2020 05 01; 51(5):262-270.. View in PubMed
  • Incidence, prevalence, and risk factors of infectious uveitis and scleritis in the United States: A claims-based analysis. PLoS One. 2020; 15(8):e0237995.. View in PubMed
  • Astigmatic outcomes in myopic wavefront-guided laser in situ keratomileusis versus wavefront-guided photorefractive keratectomy using vector analysis. J Cataract Refract Surg. 2018 Nov; 44(11):1350-1354.. View in PubMed
  • Vector Analysis of 1-Year Astigmatic Outcomes From a Randomized Fellow Eye Comparison of Photorefractive Keratectomy Using 2 Excimer Laser Platforms. Eye Contact Lens. 2018 Sep; 44 Suppl 1:S71-S76.. View in PubMed
  • Reply. Retina. 2017 06; 37(6):e77.. View in PubMed
  • Reply. Ophthalmology. 2017 06; 124(6):e53.. View in PubMed
  • POLYPOIDAL CHOROIDAL VASCULOPATHY: A CLINICOPATHOLOGIC STUDY. Retin Cases Brief Rep. 2017 Winter; 11 Suppl 1:S128-S131.. View in PubMed
  • Chronic Vascular Arrest as a Predictor of Bevacizumab Treatment Failure in Retinopathy of Prematurity. Ophthalmology. 2016 10; 123(10):2166-75.. View in PubMed
  • Non-Mydriatic Fundus Camera Screening for Referral-Warranted Diabetic Retinopathy in a Northern California Safety-Net Setting. Ophthalmic Surg Lasers Imaging Retina. 2016 07 01; 47(7):636-42.. View in PubMed
  • SMARTPHONE-BASED DILATED FUNDUS PHOTOGRAPHY AND NEAR VISUAL ACUITY TESTING AS INEXPENSIVE SCREENING TOOLS TO DETECT REFERRAL WARRANTED DIABETIC EYE DISEASE. Retina. 2016 May; 36(5):1000-8.. View in PubMed
  • Vector analysis of 1-year astigmatic outcomes from a prospective, randomized, fellow eye comparison of wavefront-guided and wavefront-optimized LASIK in myopes. J Refract Surg. 2015 May; 31(5):322-7.. View in PubMed
  • Effect of ranibizumab on high-speed indocyanine green angiography and minimum intensity projection optical coherence tomography findings in neovascular age-related macular degeneration. Retina. 2015 Jan; 35(1):58-68.. View in PubMed
  • Assessment of HBV preventive services in a medically underserved Asian and Pacific Islander population using provider and patient data. J Gen Intern Med. 2015 Jan; 30(1):68-74.. View in PubMed
  • Hepatitis B management in vulnerable populations: gaps in disease monitoring and opportunities for improved care. Dig Dis Sci. 2014 Jan; 59(1):46-56.. View in PubMed
  • Drusen regression is associated with local changes in fundus autofluorescence in intermediate age-related macular degeneration. Am J Ophthalmol. 2013 Sep; 156(3):532-542.e1.. View in PubMed
  • Prevalence and progression of pigment clumping associated with idiopathic macular telangiectasia type 2. Retina. 2013 Apr; 33(4):762-70.. View in PubMed
  • Longitudinal analysis of retinal hemangioblastomatosis and visual function in ocular von Hippel-Lindau disease. Ophthalmology. 2012 Dec; 119(12):2622-30.. View in PubMed
  • Treatment of nonneovascular idiopathic macular telangiectasia type 2 with intravitreal ranibizumab: results of a phase II clinical trial. Retina. 2012 May; 32(5):996-1006.. View in PubMed
  • Identification of rat ventral tegmental area GABAergic neurons. PLoS One. 2012; 7(7):e42365.. View in PubMed
  • A model for interprofessional health disparities education: student-led curriculum on chronic hepatitis B infection. J Gen Intern Med. 2010 May; 25 Suppl 2:S140-5.. View in PubMed
  • Delays in neural processing during working memory encoding in normal aging. Neuropsychologia. 2010 Jan; 48(1):13-25.. View in PubMed

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